Predicted complex interactions
CXCL11_HUMAN + CXCR5
SUMMARY
- Chemokine
- CXCL11_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR5 View partner entry
- Partner description
- UniProt: P32302; Gene: cxcr5_human; Family: Chemokine
- Interactions detected
- 134
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PHE 1 | NTc.Cm29 | ILE 103 | 2.56x56 | Hydrophobic |
| PHE 1 | NTc.Cm29 | ILE 103 | 2.56x56 | VdWContact |
| PHE 1 | NTc.Cm29 | ALA 107 | 2.60x60 | Hydrophobic |
| PHE 1 | NTc.Cm29 | ALA 107 | 2.60x60 | VdWContact |
| PHE 1 | NTc.Cm29 | VAL 125 | 3.28x28 | Hydrophobic |
| PHE 1 | NTc.Cm29 | VAL 125 | 3.28x28 | VdWContact |
| PHE 1 | NTc.Cm29 | HIS 129 | 3.32x32 | Hydrophobic |
| PHE 1 | NTc.Cm29 | GLU 308 | 7.39x38 | Cationic |
| PHE 1 | NTc.Cm29 | GLU 308 | 7.39x38 | HBDonor |
| PHE 1 | NTc.Cm29 | GLU 308 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm28 | GLU 110 | 2.63x63 | Hydrophobic |
| PRO 2 | NTc.Cm28 | GLU 110 | 2.63x63 | VdWContact |
| MET 3 | NTc.Cm27 | ILE 126 | 3.29x29 | Hydrophobic |
| MET 3 | NTc.Cm27 | ILE 126 | 3.29x29 | VdWContact |
| MET 3 | NTc.Cm27 | HIS 129 | 3.32x32 | Hydrophobic |
| MET 3 | NTc.Cm27 | HIS 129 | 3.32x32 | VdWContact |
| PHE 4 | NTc.Cm26 | ARG 219 | 5.39x40 | VdWContact |
| PHE 4 | NTc.Cm26 | TYR 275 | 6.51x51 | Hydrophobic |
| PHE 4 | NTc.Cm26 | TYR 275 | 6.51x51 | VdWContact |
| PHE 4 | NTc.Cm26 | ILE 304 | 7.35x34 | Hydrophobic |
| PHE 4 | NTc.Cm26 | ILE 304 | 7.35x34 | VdWContact |
| LYS 5 | NTc.Cm25 | LYS 50 | 1.31x31 | VdWContact |
| ARG 6 | NTc.Cm24 | GLN 206 | - | HBDonor |
| ARG 6 | NTc.Cm24 | GLN 206 | - | VdWContact |
| ARG 6 | NTc.Cm24 | ARG 286 | 6.62x62 | VdWContact |
| ARG 8 | NTc.Cm22 | ASP 282 | 6.58x58 | Cationic |
| ARG 8 | NTc.Cm22 | ALA 285 | 6.61x61 | VdWContact |
| ARG 8 | NTc.Cm22 | LEU 296 | 7.27x26 | VdWContact |
| ARG 8 | NTc.Cm22 | ASN 297 | 7.28x27 | HBDonor |
| ARG 8 | NTc.Cm22 | ASN 297 | 7.28x27 | Hydrophobic |
| ARG 8 | NTc.Cm22 | ASN 297 | 7.28x27 | VdWContact |
| ARG 8 | NTc.Cm22 | LEU 300 | 7.31x30 | VdWContact |
| CYS 9 | NTc.Cm21 | ASN 297 | 7.28x27 | VdWContact |
| LEU 10 | NTc.Cm20 | LEU 37 | - | Hydrophobic |
| LEU 10 | NTc.Cm20 | LEU 37 | - | VdWContact |
| LEU 10 | NTc.Cm20 | CYS 38 | - | HBAcceptor |
| LEU 10 | NTc.Cm20 | CYS 38 | - | VdWContact |
| LEU 10 | NTc.Cm20 | ALA 40 | - | Hydrophobic |
| LEU 10 | NTc.Cm20 | ALA 40 | - | VdWContact |
| ILE 12 | NTc.Cm18 | HIS 36 | - | HBDonor |
| ILE 12 | NTc.Cm18 | HIS 36 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | HIS 36 | - | VdWContact |
| ILE 12 | NTc.Cm18 | CYS 38 | - | VdWContact |
| ILE 12 | NTc.Cm18 | ASN 292 | - | VdWContact |
| ILE 12 | NTc.Cm18 | THR 293 | 7.24x23 | VdWContact |
| ILE 12 | NTc.Cm18 | CYS 294 | 7.25x24 | Hydrophobic |
| ILE 12 | NTc.Cm18 | CYS 294 | 7.25x24 | VdWContact |
| VAL 16 | NTc.Cm14 | VAL 33 | - | Hydrophobic |
| LYS 17 | NTc.Cm13 | ASP 29 | - | Cationic |
| ALA 18 | NTc.Cm12 | ASP 25 | - | VdWContact |
| LYS 20 | NTc.Cm10 | ASN 28 | - | VdWContact |
| VAL 21 | NTc.Cm9 | PHE 18 | - | Hydrophobic |
| VAL 21 | NTc.Cm9 | PHE 18 | - | VdWContact |
| VAL 21 | NTc.Cm9 | LEU 21 | - | Hydrophobic |
| ALA 22 | NTc.Cm8 | PHE 18 | - | Hydrophobic |
| ALA 22 | NTc.Cm8 | PHE 18 | - | VdWContact |
| ILE 24 | NTc.Cm6 | LEU 11 | - | Hydrophobic |
| ILE 24 | NTc.Cm6 | LEU 11 | - | VdWContact |
| ILE 24 | NTc.Cm6 | LEU 14 | - | Hydrophobic |
| GLU 25 | NTc.Cm5 | LEU 11 | - | HBAcceptor |
| GLU 25 | NTc.Cm5 | LEU 11 | - | VdWContact |
| LYS 26 | NTc.Cm4 | GLU 8 | - | Cationic |
| LYS 26 | NTc.Cm4 | GLU 8 | - | HBDonor |
| LYS 26 | NTc.Cm4 | GLU 8 | - | VdWContact |
| LYS 26 | NTc.Cm4 | ASP 10 | - | Cationic |
| LYS 26 | NTc.Cm4 | ASP 10 | - | HBDonor |
| LYS 26 | NTc.Cm4 | ASP 10 | - | VdWContact |
| ALA 27 | NTc.Cm3 | GLU 8 | - | VdWContact |
| ALA 27 | NTc.Cm3 | MET 9 | - | HBAcceptor |
| ALA 27 | NTc.Cm3 | MET 9 | - | HBDonor |
| ALA 27 | NTc.Cm3 | MET 9 | - | VdWContact |
| ALA 27 | NTc.Cm3 | LEU 14 | - | Hydrophobic |
| SER 28 | NTc.Cm2 | GLU 8 | - | VdWContact |
| ILE 29 | NTc.Cm1 | THR 6 | - | VdWContact |
| ILE 29 | NTc.Cm1 | LEU 7 | - | HBAcceptor |
| ILE 29 | NTc.Cm1 | LEU 7 | - | HBDonor |
| ILE 29 | NTc.Cm1 | LEU 7 | - | VdWContact |
| MET 30 | CX.1 | LEU 5 | - | VdWContact |
| MET 30 | CX.1 | THR 6 | - | Hydrophobic |
| MET 30 | CX.1 | THR 6 | - | VdWContact |
| MET 30 | CX.1 | HIS 195 | - | Hydrophobic |
| TYR 31 | CX.4 | LEU 5 | - | HBDonor |
| TYR 31 | CX.4 | LEU 5 | - | VdWContact |
| TYR 31 | CX.4 | LEU 7 | - | Hydrophobic |
| TYR 31 | CX.4 | LEU 7 | - | VdWContact |
| SER 33 | cxb1.1 | LEU 5 | - | VdWContact |
| ASN 34 | cxb1.2 | PHE 204 | 45.52x52 | VdWContact |
| ASN 34 | cxb1.2 | SER 205 | - | VdWContact |
| ASN 34 | cxb1.2 | GLN 206 | - | HBAcceptor |
| ASN 34 | cxb1.2 | GLN 206 | - | Hydrophobic |
| ASN 34 | cxb1.2 | GLN 206 | - | VdWContact |
| ASP 37 | cxb1.7 | LYS 288 | 6.64x64 | Anionic |
| ASP 37 | cxb1.7 | LYS 288 | 6.64x64 | HBAcceptor |
| ASP 37 | cxb1.7 | LYS 288 | 6.64x64 | VdWContact |
| ILE 42 | cxb1.15 | LEU 37 | - | Hydrophobic |
| LYS 46 | B1.3 | LEU 11 | - | VdWContact |
| GLN 51 | b1b2.4 | ASN 35 | - | HBAcceptor |
| GLN 51 | b1b2.4 | ASN 35 | - | VdWContact |
| GLN 51 | b1b2.4 | LEU 37 | - | Hydrophobic |
| GLN 51 | b1b2.4 | LEU 37 | - | VdWContact |
| ARG 52 | b1b2.6 | VAL 33 | - | VdWContact |
| ARG 52 | b1b2.6 | ASN 35 | - | VdWContact |
| CYS 53 | b1b2.7 | LEU 37 | - | VdWContact |
| LYS 59 | b1b2.14 | LEU 24 | - | Hydrophobic |
| LYS 59 | b1b2.14 | LEU 24 | - | VdWContact |
| GLN 60 | b1b2.16 | LEU 21 | - | Hydrophobic |
| GLN 60 | b1b2.16 | LEU 21 | - | VdWContact |
| GLN 60 | b1b2.16 | ASP 25 | - | HBDonor |
| GLN 60 | b1b2.16 | ASP 25 | - | VdWContact |
| LEU 63 | B2.3 | LEU 17 | - | Hydrophobic |
| LEU 63 | B2.3 | GLU 20 | - | Hydrophobic |
| LEU 63 | B2.3 | GLU 20 | - | VdWContact |
| LEU 63 | B2.3 | LEU 21 | - | Hydrophobic |
| LEU 63 | B2.3 | LEU 24 | - | Hydrophobic |
| LEU 63 | B2.3 | LEU 24 | - | VdWContact |
| ILE 64 | B2.4 | LEU 14 | - | Hydrophobic |
| ILE 64 | B2.4 | LEU 17 | - | Hydrophobic |
| LYS 67 | b2b3.2 | MET 9 | - | Hydrophobic |
| LYS 67 | b2b3.2 | ASN 13 | - | HBDonor |
| LYS 67 | b2b3.2 | ASN 13 | - | VdWContact |
| LYS 67 | b2b3.2 | ASP 16 | - | Cationic |
| LYS 67 | b2b3.2 | ASP 16 | - | HBDonor |
| LYS 67 | b2b3.2 | ASP 16 | - | VdWContact |
| LYS 67 | b2b3.2 | LEU 17 | - | HBDonor |
| LYS 67 | b2b3.2 | LEU 17 | - | Hydrophobic |
| LYS 67 | b2b3.2 | LEU 17 | - | VdWContact |
| VAL 68 | b2b3.3 | LEU 7 | - | Hydrophobic |
| VAL 68 | b2b3.3 | LEU 7 | - | VdWContact |
| VAL 68 | b2b3.3 | MET 9 | - | Hydrophobic |
| VAL 68 | b2b3.3 | MET 9 | - | VdWContact |
| LYS 71 | b2b3.12 | ASN 13 | - | Hydrophobic |
| LYS 71 | b2b3.12 | ASN 13 | - | VdWContact |
| ASN 72 | B3.1 | LEU 7 | - | Hydrophobic |
| PHE 73 | B3.2 | TYR 3 | - | Hydrophobic |
