Predicted complex interactions
CXCL13_HUMAN + CXCR5
SUMMARY
- Chemokine
- CXCL13_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR5 View partner entry
- Partner description
- UniProt: P32302; Gene: cxcr5_human; Family: Chemokine
- Interactions detected
- 172
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm32 | ILE 103 | 2.56x56 | Hydrophobic |
| VAL 1 | NTc.Cm32 | GLU 110 | 2.63x63 | Cationic |
| VAL 1 | NTc.Cm32 | GLU 110 | 2.63x63 | HBDonor |
| VAL 1 | NTc.Cm32 | GLU 110 | 2.63x63 | VdWContact |
| VAL 1 | NTc.Cm32 | TRP 115 | 23.50x50 | Hydrophobic |
| VAL 1 | NTc.Cm32 | TRP 115 | 23.50x50 | VdWContact |
| VAL 1 | NTc.Cm32 | VAL 125 | 3.28x28 | Hydrophobic |
| VAL 1 | NTc.Cm32 | VAL 125 | 3.28x28 | VdWContact |
| VAL 1 | NTc.Cm32 | ILE 126 | 3.29x29 | Hydrophobic |
| VAL 1 | NTc.Cm32 | ILE 126 | 3.29x29 | VdWContact |
| VAL 1 | NTc.Cm32 | CYS 202 | 45.50x50 | Hydrophobic |
| VAL 1 | NTc.Cm32 | CYS 202 | 45.50x50 | VdWContact |
| LEU 2 | NTc.Cm31 | TYR 58 | 1.39x39 | Hydrophobic |
| LEU 2 | NTc.Cm31 | TYR 58 | 1.39x39 | VdWContact |
| LEU 2 | NTc.Cm31 | ALA 107 | 2.60x60 | Hydrophobic |
| LEU 2 | NTc.Cm31 | ALA 107 | 2.60x60 | VdWContact |
| LEU 2 | NTc.Cm31 | HIS 129 | 3.32x32 | Hydrophobic |
| LEU 2 | NTc.Cm31 | GLU 308 | 7.39x38 | VdWContact |
| LEU 2 | NTc.Cm31 | LEU 312 | 7.43x42 | Hydrophobic |
| GLU 3 | NTc.Cm30 | ARG 219 | 5.39x40 | Anionic |
| GLU 3 | NTc.Cm30 | ARG 219 | 5.39x40 | HBAcceptor |
| GLU 3 | NTc.Cm30 | ARG 219 | 5.39x40 | VdWContact |
| GLU 3 | NTc.Cm30 | TYR 275 | 6.51x51 | Hydrophobic |
| GLU 3 | NTc.Cm30 | TYR 275 | 6.51x51 | VdWContact |
| GLU 3 | NTc.Cm30 | ILE 279 | 6.55x55 | Hydrophobic |
| GLU 3 | NTc.Cm30 | ILE 279 | 6.55x55 | VdWContact |
| GLU 3 | NTc.Cm30 | ILE 304 | 7.35x34 | Hydrophobic |
| GLU 3 | NTc.Cm30 | GLU 308 | 7.39x38 | HBDonor |
| GLU 3 | NTc.Cm30 | GLU 308 | 7.39x38 | VdWContact |
| VAL 4 | NTc.Cm29 | LYS 50 | 1.31x31 | Hydrophobic |
| VAL 4 | NTc.Cm29 | LYS 50 | 1.31x31 | VdWContact |
| VAL 4 | NTc.Cm29 | VAL 54 | 1.35x35 | Hydrophobic |
| VAL 4 | NTc.Cm29 | THR 305 | 7.36x35 | Hydrophobic |
| VAL 4 | NTc.Cm29 | THR 305 | 7.36x35 | VdWContact |
| VAL 4 | NTc.Cm29 | GLU 308 | 7.39x38 | HBDonor |
| VAL 4 | NTc.Cm29 | GLU 308 | 7.39x38 | VdWContact |
| TYR 5 | NTc.Cm28 | VAL 54 | 1.35x35 | Hydrophobic |
| TYR 5 | NTc.Cm28 | ALA 107 | 2.60x60 | HBDonor |
| TYR 5 | NTc.Cm28 | ALA 107 | 2.60x60 | Hydrophobic |
| TYR 5 | NTc.Cm28 | ALA 107 | 2.60x60 | VdWContact |
| TYR 5 | NTc.Cm28 | GLU 110 | 2.63x63 | Hydrophobic |
| TYR 5 | NTc.Cm28 | GLY 111 | 2.64x64 | VdWContact |
| TYR 5 | NTc.Cm28 | ARG 201 | - | HBAcceptor |
| TYR 5 | NTc.Cm28 | ARG 201 | - | VdWContact |
| TYR 6 | NTc.Cm27 | THR 203 | 45.51x51 | Hydrophobic |
| TYR 6 | NTc.Cm27 | THR 203 | 45.51x51 | VdWContact |
| TYR 6 | NTc.Cm27 | PHE 204 | 45.52x52 | HBDonor |
| TYR 6 | NTc.Cm27 | PHE 204 | 45.52x52 | Hydrophobic |
| TYR 6 | NTc.Cm27 | PHE 204 | 45.52x52 | VdWContact |
| TYR 6 | NTc.Cm27 | ARG 286 | 6.62x62 | HBAcceptor |
| TYR 6 | NTc.Cm27 | ARG 286 | 6.62x62 | VdWContact |
| THR 7 | NTc.Cm26 | LYS 50 | 1.31x31 | VdWContact |
| THR 7 | NTc.Cm26 | PRO 301 | 7.32x31 | Hydrophobic |
| THR 7 | NTc.Cm26 | PRO 301 | 7.32x31 | VdWContact |
| THR 7 | NTc.Cm26 | ILE 304 | 7.35x34 | Hydrophobic |
| THR 7 | NTc.Cm26 | ILE 304 | 7.35x34 | VdWContact |
| SER 8 | NTc.Cm25 | ARG 201 | - | HBAcceptor |
| SER 8 | NTc.Cm25 | ARG 201 | - | VdWContact |
| LEU 9 | NTc.Cm24 | THR 203 | 45.51x51 | Hydrophobic |
| LEU 9 | NTc.Cm24 | ARG 286 | 6.62x62 | HBAcceptor |
| LEU 9 | NTc.Cm24 | ARG 286 | 6.62x62 | VdWContact |
| ARG 10 | NTc.Cm23 | ASP 282 | 6.58x58 | Cationic |
| ARG 10 | NTc.Cm23 | ASP 282 | 6.58x58 | VdWContact |
| ARG 10 | NTc.Cm23 | ASN 297 | 7.28x27 | HBDonor |
| ARG 10 | NTc.Cm23 | ASN 297 | 7.28x27 | VdWContact |
| ARG 10 | NTc.Cm23 | LEU 300 | 7.31x30 | VdWContact |
| ARG 12 | NTc.Cm21 | LEU 37 | - | Hydrophobic |
| ARG 12 | NTc.Cm21 | LEU 37 | - | VdWContact |
| ARG 12 | NTc.Cm21 | CYS 38 | - | HBAcceptor |
| ARG 12 | NTc.Cm21 | CYS 38 | - | VdWContact |
| ARG 12 | NTc.Cm21 | ALA 40 | - | Hydrophobic |
| ARG 12 | NTc.Cm21 | ALA 40 | - | VdWContact |
| VAL 14 | NTc.Cm19 | HIS 36 | - | HBDonor |
| VAL 14 | NTc.Cm19 | HIS 36 | - | VdWContact |
| VAL 14 | NTc.Cm19 | CYS 38 | - | VdWContact |
| VAL 14 | NTc.Cm19 | ASN 292 | - | Hydrophobic |
| VAL 14 | NTc.Cm19 | ASN 292 | - | VdWContact |
| GLN 15 | NTc.Cm18 | HIS 36 | - | Hydrophobic |
| GLU 16 | NTc.Cm17 | LYS 288 | 6.64x64 | Anionic |
| GLU 16 | NTc.Cm17 | LYS 288 | 6.64x64 | HBAcceptor |
| GLU 16 | NTc.Cm17 | LYS 288 | 6.64x64 | VdWContact |
| VAL 19 | NTc.Cm14 | TYR 27 | - | Hydrophobic |
| VAL 19 | NTc.Cm14 | TYR 27 | - | VdWContact |
| PHE 20 | NTc.Cm13 | PHE 18 | - | Hydrophobic |
| PHE 20 | NTc.Cm13 | LEU 21 | - | Hydrophobic |
| PHE 20 | NTc.Cm13 | LEU 21 | - | VdWContact |
| PHE 20 | NTc.Cm13 | ASP 22 | - | VdWContact |
| PHE 20 | NTc.Cm13 | ASP 25 | - | Hydrophobic |
| PHE 20 | NTc.Cm13 | ASP 25 | - | VdWContact |
| PHE 20 | NTc.Cm13 | TYR 27 | - | VdWContact |
| ILE 21 | NTc.Cm12 | TYR 27 | - | Hydrophobic |
| PRO 22 | NTc.Cm11 | ASP 22 | - | VdWContact |
| PRO 22 | NTc.Cm11 | TYR 27 | - | Hydrophobic |
| PRO 22 | NTc.Cm11 | TYR 27 | - | VdWContact |
| ARG 23 | NTc.Cm10 | LEU 11 | - | VdWContact |
| ARG 23 | NTc.Cm10 | PHE 18 | - | Hydrophobic |
| ARG 23 | NTc.Cm10 | PHE 18 | - | VdWContact |
| ARG 23 | NTc.Cm10 | ASP 22 | - | HBDonor |
| ARG 23 | NTc.Cm10 | ASP 22 | - | VdWContact |
| PHE 25 | NTc.Cm8 | TYR 27 | - | Hydrophobic |
| PHE 25 | NTc.Cm8 | ASP 29 | - | Hydrophobic |
| PHE 25 | NTc.Cm8 | ASP 29 | - | VdWContact |
| ILE 26 | NTc.Cm7 | LEU 11 | - | Hydrophobic |
| ILE 26 | NTc.Cm7 | PHE 18 | - | Hydrophobic |
| ILE 26 | NTc.Cm7 | PHE 18 | - | VdWContact |
| ASP 27 | NTc.Cm6 | LEU 11 | - | VdWContact |
| ARG 28 | NTc.Cm5 | GLU 8 | - | Cationic |
| ARG 28 | NTc.Cm5 | GLU 8 | - | VdWContact |
| ARG 28 | NTc.Cm5 | LEU 11 | - | VdWContact |
| ILE 29 | NTc.Cm4 | GLU 8 | - | VdWContact |
| ILE 29 | NTc.Cm4 | MET 9 | - | HBAcceptor |
| ILE 29 | NTc.Cm4 | MET 9 | - | Hydrophobic |
| ILE 29 | NTc.Cm4 | MET 9 | - | VdWContact |
| ILE 29 | NTc.Cm4 | LEU 11 | - | Hydrophobic |
| ILE 29 | NTc.Cm4 | PHE 18 | - | Hydrophobic |
| ILE 31 | NTc.Cm2 | LEU 5 | - | Hydrophobic |
| ILE 31 | NTc.Cm2 | LEU 5 | - | VdWContact |
| ILE 31 | NTc.Cm2 | THR 6 | - | VdWContact |
| ILE 31 | NTc.Cm2 | MET 9 | - | Hydrophobic |
| ILE 31 | NTc.Cm2 | MET 9 | - | VdWContact |
| PRO 33 | CX.1 | LEU 5 | - | Hydrophobic |
| PRO 33 | CX.1 | LEU 5 | - | VdWContact |
| PRO 33 | CX.1 | HIS 194 | - | Hydrophobic |
| PRO 33 | CX.1 | HIS 194 | - | VdWContact |
| GLY 35 | CX.5 | GLN 206 | - | VdWContact |
| ASN 36 | cxb1.1 | GLN 192 | - | HBDonor |
| ASN 36 | cxb1.1 | GLN 192 | - | VdWContact |
| ASN 36 | cxb1.1 | GLY 193 | - | VdWContact |
| ASN 36 | cxb1.1 | HIS 194 | - | VdWContact |
| GLY 37 | cxb1.2 | ARG 286 | 6.62x62 | VdWContact |
| PRO 39 | cxb1.6 | THR 212 | - | Hydrophobic |
| PRO 39 | cxb1.6 | PHE 216 | 5.36x37 | Hydrophobic |
| PRO 39 | cxb1.6 | ARG 286 | 6.62x62 | Hydrophobic |
| ARG 40 | cxb1.7 | LYS 288 | 6.64x64 | VdWContact |
| ILE 44 | cxb1.14 | LEU 37 | - | Hydrophobic |
| ILE 44 | cxb1.14 | LEU 37 | - | VdWContact |
| LYS 47 | B1.1 | TYR 27 | - | HBDonor |
| LYS 47 | B1.1 | TYR 27 | - | VdWContact |
| LYS 47 | B1.1 | ASP 29 | - | Cationic |
| SER 51 | B1.5 | VAL 33 | - | VdWContact |
| SER 51 | B1.5 | GLU 34 | - | HBAcceptor |
| SER 51 | B1.5 | GLU 34 | - | VdWContact |
| ILE 52 | B1.6 | GLU 34 | - | HBDonor |
| ILE 52 | B1.6 | GLU 34 | - | VdWContact |
| ILE 52 | B1.6 | ASN 35 | - | VdWContact |
| ILE 52 | B1.6 | HIS 36 | - | HBAcceptor |
| ILE 52 | B1.6 | HIS 36 | - | VdWContact |
| ILE 52 | B1.6 | LEU 37 | - | Hydrophobic |
| ILE 52 | B1.6 | LEU 37 | - | VdWContact |
| VAL 53 | B1.7 | HIS 36 | - | Hydrophobic |
| VAL 53 | B1.7 | HIS 36 | - | VdWContact |
| CYS 54 | b1b2.4 | HIS 36 | - | Hydrophobic |
| CYS 54 | b1b2.4 | HIS 36 | - | VdWContact |
| TRP 61 | b1b2.13 | PHE 18 | - | Hydrophobic |
| TRP 61 | b1b2.13 | LEU 21 | - | Hydrophobic |
| ARG 64 | B2.1 | LEU 17 | - | Hydrophobic |
| MET 65 | B2.2 | MET 9 | - | Hydrophobic |
| MET 65 | B2.2 | MET 9 | - | VdWContact |
| MET 65 | B2.2 | LEU 14 | - | Hydrophobic |
| MET 65 | B2.2 | LEU 17 | - | Hydrophobic |
| MET 65 | B2.2 | LEU 17 | - | VdWContact |
| VAL 68 | B2.5 | LEU 14 | - | Hydrophobic |
| VAL 68 | B2.5 | LEU 17 | - | Hydrophobic |
| LEU 69 | B2.6 | MET 9 | - | Hydrophobic |
| LEU 69 | B2.6 | MET 9 | - | VdWContact |
| LEU 69 | B2.6 | LEU 14 | - | Hydrophobic |
| LEU 69 | B2.6 | LEU 14 | - | VdWContact |
| ARG 72 | b2b3.11 | ASN 13 | - | HBDonor |
| ARG 72 | b2b3.11 | ASN 13 | - | VdWContact |
| ARG 72 | b2b3.11 | ASP 16 | - | Cationic |
| ARG 72 | b2b3.11 | ASP 16 | - | VdWContact |
| SER 73 | b2b3.12 | TYR 3 | - | VdWContact |
