Predicted complex interactions
CXCL16_HUMAN + CXCR5
SUMMARY
- Chemokine
- CXCL16_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR5 View partner entry
- Partner description
- UniProt: P32302; Gene: cxcr5_human; Family: Chemokine
- Interactions detected
- 102
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ASN 1 | NTc.Cm56 | TYR 58 | 1.39x39 | HBDonor |
| ASN 1 | NTc.Cm56 | TYR 58 | 1.39x39 | VdWContact |
| ASN 1 | NTc.Cm56 | GLU 110 | 2.63x63 | Cationic |
| ASN 1 | NTc.Cm56 | GLU 308 | 7.39x38 | Cationic |
| ASN 1 | NTc.Cm56 | GLU 308 | 7.39x38 | HBDonor |
| ASN 1 | NTc.Cm56 | GLU 308 | 7.39x38 | VdWContact |
| GLU 2 | NTc.Cm55 | LYS 130 | 3.33x33 | Anionic |
| GLU 2 | NTc.Cm55 | LYS 130 | 3.33x33 | HBAcceptor |
| GLU 2 | NTc.Cm55 | LYS 130 | 3.33x33 | VdWContact |
| GLU 2 | NTc.Cm55 | ARG 219 | 5.39x40 | Anionic |
| GLU 2 | NTc.Cm55 | ARG 219 | 5.39x40 | VdWContact |
| GLU 2 | NTc.Cm55 | TYR 275 | 6.51x51 | HBAcceptor |
| GLU 2 | NTc.Cm55 | TYR 275 | 6.51x51 | VdWContact |
| GLU 2 | NTc.Cm55 | GLU 308 | 7.39x38 | HBDonor |
| GLU 2 | NTc.Cm55 | GLU 308 | 7.39x38 | VdWContact |
| GLY 3 | NTc.Cm54 | ILE 304 | 7.35x34 | VdWContact |
| SER 4 | NTc.Cm53 | ARG 201 | - | VdWContact |
| VAL 5 | NTc.Cm52 | ARG 201 | - | Hydrophobic |
| VAL 5 | NTc.Cm52 | ARG 201 | - | VdWContact |
| VAL 5 | NTc.Cm52 | THR 203 | 45.51x51 | Hydrophobic |
| VAL 5 | NTc.Cm52 | THR 203 | 45.51x51 | VdWContact |
| THR 6 | NTc.Cm51 | TRP 215 | 5.35x36 | Hydrophobic |
| THR 6 | NTc.Cm51 | TRP 215 | 5.35x36 | VdWContact |
| THR 6 | NTc.Cm51 | ARG 286 | 6.62x62 | HBAcceptor |
| THR 6 | NTc.Cm51 | ARG 286 | 6.62x62 | VdWContact |
| TYR 10 | NTc.Cm47 | ALA 285 | 6.61x61 | Hydrophobic |
| TYR 10 | NTc.Cm47 | ARG 286 | 6.62x62 | Hydrophobic |
| TYR 10 | NTc.Cm47 | ASN 292 | - | HBDonor |
| TYR 10 | NTc.Cm47 | ASN 292 | - | Hydrophobic |
| TYR 10 | NTc.Cm47 | ASN 292 | - | VdWContact |
| LYS 13 | NTc.Cm44 | ASN 13 | - | HBDonor |
| LYS 13 | NTc.Cm44 | ASN 13 | - | Hydrophobic |
| LYS 13 | NTc.Cm44 | ASN 13 | - | VdWContact |
| LYS 13 | NTc.Cm44 | LEU 14 | - | VdWContact |
| LYS 13 | NTc.Cm44 | LEU 17 | - | Hydrophobic |
| LYS 13 | NTc.Cm44 | LEU 17 | - | VdWContact |
| GLN 24 | NTc.Cm33 | PHE 18 | - | Hydrophobic |
| GLN 24 | NTc.Cm33 | PHE 18 | - | VdWContact |
| PHE 25 | NTc.Cm32 | LEU 17 | - | Hydrophobic |
| PHE 25 | NTc.Cm32 | LEU 17 | - | VdWContact |
| PHE 25 | NTc.Cm32 | PHE 18 | - | Hydrophobic |
| PHE 25 | NTc.Cm32 | PHE 18 | - | VdWContact |
| PHE 25 | NTc.Cm32 | LEU 21 | - | Hydrophobic |
| PHE 25 | NTc.Cm32 | LEU 21 | - | VdWContact |
| ARG 28 | NTc.Cm29 | PHE 18 | - | VdWContact |
| ARG 28 | NTc.Cm29 | LEU 21 | - | Hydrophobic |
| ARG 28 | NTc.Cm29 | LEU 21 | - | VdWContact |
| ARG 28 | NTc.Cm29 | ASP 22 | - | Cationic |
| ARG 28 | NTc.Cm29 | ASP 22 | - | HBDonor |
| ARG 28 | NTc.Cm29 | ASP 22 | - | VdWContact |
| ARG 28 | NTc.Cm29 | ASP 25 | - | Cationic |
| ARG 28 | NTc.Cm29 | ASP 25 | - | HBDonor |
| ARG 28 | NTc.Cm29 | ASP 25 | - | VdWContact |
| LEU 29 | NTc.Cm28 | LEU 21 | - | Hydrophobic |
| LYS 31 | NTc.Cm26 | LEU 24 | - | HBDonor |
| LYS 31 | NTc.Cm26 | LEU 24 | - | VdWContact |
| LYS 31 | NTc.Cm26 | ASP 25 | - | Cationic |
| LYS 31 | NTc.Cm26 | ASP 25 | - | HBDonor |
| LYS 31 | NTc.Cm26 | ASP 25 | - | VdWContact |
| HIS 32 | NTc.Cm25 | LEU 21 | - | Hydrophobic |
| HIS 32 | NTc.Cm25 | LEU 24 | - | Hydrophobic |
| HIS 32 | NTc.Cm25 | LEU 24 | - | VdWContact |
| ARG 34 | NTc.Cm23 | LEU 37 | - | VdWContact |
| ALA 35 | NTc.Cm22 | HIS 195 | - | Hydrophobic |
| ALA 35 | NTc.Cm22 | HIS 195 | - | VdWContact |
| TYR 36 | NTc.Cm21 | HIS 194 | - | Hydrophobic |
| TYR 36 | NTc.Cm21 | HIS 194 | - | VdWContact |
| TYR 36 | NTc.Cm21 | HIS 195 | - | HBDonor |
| TYR 36 | NTc.Cm21 | HIS 195 | - | Hydrophobic |
| TYR 36 | NTc.Cm21 | HIS 195 | - | VdWContact |
| ARG 38 | NTc.Cm19 | HIS 194 | - | HBDonor |
| ARG 38 | NTc.Cm19 | HIS 194 | - | Hydrophobic |
| ARG 38 | NTc.Cm19 | HIS 194 | - | VdWContact |
| LEU 40 | NTc.Cm17 | SER 205 | - | VdWContact |
| LEU 40 | NTc.Cm17 | GLN 206 | - | VdWContact |
| LEU 40 | NTc.Cm17 | GLU 207 | - | Hydrophobic |
| LEU 40 | NTc.Cm17 | GLU 207 | - | VdWContact |
| TYR 41 | NTc.Cm16 | GLN 206 | - | VdWContact |
| TYR 41 | NTc.Cm16 | GLU 207 | - | VdWContact |
| TYR 41 | NTc.Cm16 | ASN 208 | - | Hydrophobic |
| TYR 41 | NTc.Cm16 | ASN 208 | - | VdWContact |
| TYR 41 | NTc.Cm16 | GLU 211 | - | Hydrophobic |
| TYR 41 | NTc.Cm16 | GLU 211 | - | VdWContact |
| TYR 42 | NTc.Cm15 | GLN 206 | - | HBDonor |
| TYR 42 | NTc.Cm15 | GLN 206 | - | VdWContact |
| LEU 47 | NTc.Cm10 | LEU 17 | - | Hydrophobic |
| LEU 48 | NTc.Cm9 | LEU 24 | - | Hydrophobic |
| LEU 48 | NTc.Cm9 | LEU 37 | - | Hydrophobic |
| LEU 48 | NTc.Cm9 | LEU 37 | - | VdWContact |
| SER 49 | NTc.Cm8 | GLU 20 | - | HBDonor |
| SER 49 | NTc.Cm8 | GLU 20 | - | VdWContact |
| SER 49 | NTc.Cm8 | LEU 37 | - | VdWContact |
| TRP 50 | NTc.Cm7 | LEU 17 | - | Hydrophobic |
| TRP 50 | NTc.Cm7 | GLU 20 | - | HBDonor |
| TRP 50 | NTc.Cm7 | GLU 20 | - | VdWContact |
| VAL 52 | NTc.Cm5 | LEU 17 | - | Hydrophobic |
| VAL 52 | NTc.Cm5 | LEU 17 | - | VdWContact |
| MET 65 | cxb1.8 | HIS 194 | - | Hydrophobic |
| LEU 68 | cxb1.14 | HIS 195 | - | Hydrophobic |
| LEU 68 | cxb1.14 | HIS 195 | - | VdWContact |
| ASP 69 | cxb1.15 | HIS 195 | - | HBAcceptor |
| ASP 69 | cxb1.15 | HIS 195 | - | VdWContact |
