Predicted complex interactions
CXCL17_HUMAN + CXCR5
SUMMARY
- Chemokine
- CXCL17_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR5 View partner entry
- Partner description
- UniProt: P32302; Gene: cxcr5_human; Family: Chemokine
- Interactions detected
- 134
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 25 | NTc.Cm25 | HIS 195 | - | VdWContact |
| GLY 26 | NTc.Cm24 | HIS 195 | - | VdWContact |
| GLN 27 | NTc.Cm23 | HIS 195 | - | HBDonor |
| GLN 27 | NTc.Cm23 | HIS 195 | - | Hydrophobic |
| GLN 27 | NTc.Cm23 | HIS 195 | - | VdWContact |
| LYS 32 | NTc.Cm18 | ARG 201 | - | Hydrophobic |
| LYS 32 | NTc.Cm18 | ARG 201 | - | VdWContact |
| LYS 32 | NTc.Cm18 | THR 203 | 45.51x51 | Hydrophobic |
| LYS 32 | NTc.Cm18 | THR 203 | 45.51x51 | VdWContact |
| ASP 33 | NTc.Cm17 | ARG 219 | 5.39x40 | Anionic |
| ASP 33 | NTc.Cm17 | ARG 219 | 5.39x40 | HBAcceptor |
| ASP 33 | NTc.Cm17 | ARG 219 | 5.39x40 | VdWContact |
| ASP 33 | NTc.Cm17 | ARG 286 | 6.62x62 | Anionic |
| ASP 33 | NTc.Cm17 | ARG 286 | 6.62x62 | HBAcceptor |
| ASP 33 | NTc.Cm17 | ARG 286 | 6.62x62 | VdWContact |
| ASP 33 | NTc.Cm17 | ILE 304 | 7.35x34 | Hydrophobic |
| ASP 33 | NTc.Cm17 | ILE 304 | 7.35x34 | VdWContact |
| TRP 34 | NTc.Cm16 | ALA 107 | 2.60x60 | Hydrophobic |
| TRP 34 | NTc.Cm16 | ALA 107 | 2.60x60 | VdWContact |
| TRP 34 | NTc.Cm16 | GLU 110 | 2.63x63 | HBDonor |
| TRP 34 | NTc.Cm16 | GLU 110 | 2.63x63 | Hydrophobic |
| TRP 34 | NTc.Cm16 | GLU 110 | 2.63x63 | VdWContact |
| PHE 35 | NTc.Cm15 | ILE 103 | 2.56x56 | Hydrophobic |
| PHE 35 | NTc.Cm15 | VAL 125 | 3.28x28 | Hydrophobic |
| PHE 35 | NTc.Cm15 | VAL 125 | 3.28x28 | VdWContact |
| PHE 35 | NTc.Cm15 | ILE 126 | 3.29x29 | Hydrophobic |
| PHE 35 | NTc.Cm15 | ILE 126 | 3.29x29 | VdWContact |
| PHE 35 | NTc.Cm15 | HIS 129 | 3.32x32 | Hydrophobic |
| PHE 35 | NTc.Cm15 | HIS 129 | 3.32x32 | VdWContact |
| LEU 36 | NTc.Cm14 | LYS 130 | 3.33x33 | VdWContact |
| LEU 36 | NTc.Cm14 | TRP 215 | 5.35x36 | HBAcceptor |
| LEU 36 | NTc.Cm14 | TRP 215 | 5.35x36 | VdWContact |
| LEU 36 | NTc.Cm14 | ARG 219 | 5.39x40 | Hydrophobic |
| LEU 36 | NTc.Cm14 | ARG 219 | 5.39x40 | VdWContact |
| LEU 36 | NTc.Cm14 | TYR 222 | 5.42x43 | Hydrophobic |
| LEU 36 | NTc.Cm14 | TYR 275 | 6.51x51 | Hydrophobic |
| LEU 36 | NTc.Cm14 | ILE 279 | 6.55x55 | Hydrophobic |
| LEU 36 | NTc.Cm14 | ILE 279 | 6.55x55 | VdWContact |
| ARG 37 | NTc.Cm13 | GLU 110 | 2.63x63 | Cationic |
| ARG 37 | NTc.Cm13 | GLU 110 | 2.63x63 | HBDonor |
| ARG 37 | NTc.Cm13 | GLU 110 | 2.63x63 | VdWContact |
| ARG 37 | NTc.Cm13 | CYS 202 | 45.50x50 | Cationic |
| ARG 37 | NTc.Cm13 | CYS 202 | 45.50x50 | HBDonor |
| ARG 37 | NTc.Cm13 | CYS 202 | 45.50x50 | VdWContact |
| ARG 37 | NTc.Cm13 | THR 203 | 45.51x51 | Hydrophobic |
| ARG 37 | NTc.Cm13 | THR 203 | 45.51x51 | VdWContact |
| ARG 37 | NTc.Cm13 | PHE 204 | 45.52x52 | HBAcceptor |
| ARG 37 | NTc.Cm13 | PHE 204 | 45.52x52 | Hydrophobic |
| ARG 37 | NTc.Cm13 | PHE 204 | 45.52x52 | VdWContact |
| ALA 38 | NTc.Cm12 | GLN 206 | - | Hydrophobic |
| ALA 38 | NTc.Cm12 | GLN 206 | - | VdWContact |
| ALA 38 | NTc.Cm12 | TRP 215 | 5.35x36 | Hydrophobic |
| ALA 38 | NTc.Cm12 | TRP 215 | 5.35x36 | VdWContact |
| ALA 38 | NTc.Cm12 | ARG 286 | 6.62x62 | HBAcceptor |
| ALA 38 | NTc.Cm12 | ARG 286 | 6.62x62 | VdWContact |
| PRO 39 | NTc.Cm11 | PHE 204 | 45.52x52 | VdWContact |
| PRO 39 | NTc.Cm11 | GLN 206 | - | Hydrophobic |
| PRO 39 | NTc.Cm11 | GLN 206 | - | VdWContact |
| ARG 40 | NTc.Cm10 | ASP 282 | 6.58x58 | Cationic |
| ARG 40 | NTc.Cm10 | ASP 282 | 6.58x58 | HBDonor |
| ARG 40 | NTc.Cm10 | ASP 282 | 6.58x58 | VdWContact |
| ARG 40 | NTc.Cm10 | ALA 285 | 6.61x61 | VdWContact |
| ARG 40 | NTc.Cm10 | ARG 286 | 6.62x62 | Hydrophobic |
| ARG 40 | NTc.Cm10 | ARG 286 | 6.62x62 | VdWContact |
| ARG 40 | NTc.Cm10 | ASN 292 | - | HBDonor |
| ARG 40 | NTc.Cm10 | ASN 292 | - | VdWContact |
| ARG 40 | NTc.Cm10 | ASN 297 | 7.28x27 | VdWContact |
| ARG 41 | NTc.Cm9 | GLU 207 | - | Cationic |
| ARG 41 | NTc.Cm9 | GLU 207 | - | HBDonor |
| ARG 41 | NTc.Cm9 | GLU 207 | - | VdWContact |
| PHE 43 | NTc.Cm7 | GLN 209 | - | Hydrophobic |
| PHE 59 | cxb1.11 | ASN 35 | - | Hydrophobic |
| PHE 59 | cxb1.11 | ASN 35 | - | VdWContact |
| PHE 59 | cxb1.11 | LEU 37 | - | Hydrophobic |
| PHE 59 | cxb1.11 | LEU 37 | - | VdWContact |
| HIS 78 | b1b2.13 | LEU 37 | - | Hydrophobic |
| PHE 85 | b1b2.21 | ALA 40 | - | Hydrophobic |
| PHE 85 | b1b2.21 | ALA 40 | - | VdWContact |
| PHE 85 | b1b2.21 | GLU 42 | - | Hydrophobic |
| PHE 85 | b1b2.21 | GLU 42 | - | VdWContact |
| PHE 85 | b1b2.21 | GLY 298 | 7.29x28 | VdWContact |
| GLN 88 | b1b2.24 | PRO 44 | - | VdWContact |
| GLN 88 | b1b2.24 | ALA 47 | - | Hydrophobic |
| GLN 90 | B2.1 | SER 198 | - | VdWContact |
| GLN 90 | B2.1 | ARG 201 | - | HBAcceptor |
| GLN 90 | B2.1 | ARG 201 | - | VdWContact |
| LEU 91 | B2.2 | LEU 199 | - | Hydrophobic |
| ARG 92 | B2.3 | GLU 42 | - | Cationic |
| ARG 92 | B2.3 | GLU 42 | - | HBDonor |
| ARG 92 | B2.3 | GLU 42 | - | VdWContact |
| ARG 92 | B2.3 | GLY 43 | - | HBDonor |
| ARG 92 | B2.3 | GLY 43 | - | VdWContact |
| ARG 92 | B2.3 | MET 46 | - | VdWContact |
| ARG 92 | B2.3 | ALA 47 | - | Hydrophobic |
| ARG 92 | B2.3 | ALA 47 | - | VdWContact |
| ARG 92 | B2.3 | LYS 50 | 1.31x31 | HBAcceptor |
| ARG 92 | B2.3 | LYS 50 | 1.31x31 | Hydrophobic |
| ARG 92 | B2.3 | LYS 50 | 1.31x31 | VdWContact |
| ARG 92 | B2.3 | VAL 302 | 7.33x32 | VdWContact |
| SER 93 | B2.4 | ARG 201 | - | VdWContact |
| PHE 94 | B2.5 | LYS 50 | 1.31x31 | VdWContact |
| PHE 94 | B2.5 | VAL 54 | 1.35x35 | Hydrophobic |
| PHE 94 | B2.5 | VAL 54 | 1.35x35 | VdWContact |
| PHE 94 | B2.5 | PRO 55 | 1.36x36 | Hydrophobic |
| PHE 94 | B2.5 | GLY 111 | 2.64x64 | VdWContact |
| ALA 95 | B2.6 | LYS 50 | 1.31x31 | VdWContact |
| ALA 95 | B2.6 | THR 305 | 7.36x35 | VdWContact |
| LEU 96 | b2b3.2 | TYR 58 | 1.39x39 | Hydrophobic |
| LEU 96 | b2b3.2 | TYR 58 | 1.39x39 | VdWContact |
| LEU 96 | b2b3.2 | LEU 104 | 2.57x57 | Hydrophobic |
| LEU 96 | b2b3.2 | ALA 107 | 2.60x60 | Hydrophobic |
| LEU 96 | b2b3.2 | THR 305 | 7.36x35 | VdWContact |
| LEU 96 | b2b3.2 | GLU 308 | 7.39x38 | HBDonor |
| LEU 96 | b2b3.2 | GLU 308 | 7.39x38 | Hydrophobic |
| LEU 96 | b2b3.2 | GLU 308 | 7.39x38 | VdWContact |
| LEU 96 | b2b3.2 | PHE 309 | 7.40x39 | Hydrophobic |
| LEU 96 | b2b3.2 | LEU 312 | 7.43x42 | Hydrophobic |
| LEU 96 | b2b3.2 | LEU 312 | 7.43x42 | VdWContact |
| PRO 97 | b2b3.3 | GLU 308 | 7.39x38 | VdWContact |
| LEU 98 | b2b3.4 | LEU 100 | 2.53x53 | Hydrophobic |
| LEU 98 | b2b3.4 | HIS 129 | 3.32x32 | HBAcceptor |
| LEU 98 | b2b3.4 | HIS 129 | 3.32x32 | Hydrophobic |
| LEU 98 | b2b3.4 | HIS 129 | 3.32x32 | VdWContact |
| LEU 98 | b2b3.4 | LYS 130 | 3.33x33 | Anionic |
| LEU 98 | b2b3.4 | LYS 130 | 3.33x33 | HBAcceptor |
| LEU 98 | b2b3.4 | LYS 130 | 3.33x33 | VdWContact |
| LEU 98 | b2b3.4 | TRP 272 | 6.48x48 | Hydrophobic |
| LEU 98 | b2b3.4 | TRP 272 | 6.48x48 | VdWContact |
| LEU 98 | b2b3.4 | TYR 275 | 6.51x51 | HBAcceptor |
| LEU 98 | b2b3.4 | TYR 275 | 6.51x51 | Hydrophobic |
| LEU 98 | b2b3.4 | TYR 275 | 6.51x51 | VdWContact |
| LEU 98 | b2b3.4 | GLU 308 | 7.39x38 | Hydrophobic |
| LEU 98 | b2b3.4 | GLU 308 | 7.39x38 | VdWContact |
| LEU 98 | b2b3.4 | LEU 312 | 7.43x42 | Hydrophobic |
