Predicted complex interactions
CXCL4_HUMAN + CXCR5
SUMMARY
- Chemokine
- CXCL4_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR5 View partner entry
- Partner description
- UniProt: P32302; Gene: cxcr5_human; Family: Chemokine
- Interactions detected
- 111
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLU 3 | NTc.Cm38 | HIS 195 | - | Hydrophobic |
| GLU 4 | NTc.Cm37 | THR 41 | - | HBAcceptor |
| GLU 4 | NTc.Cm37 | THR 41 | - | Hydrophobic |
| GLU 4 | NTc.Cm37 | THR 41 | - | VdWContact |
| ASP 5 | NTc.Cm36 | SER 198 | - | VdWContact |
| GLY 6 | NTc.Cm35 | ALA 40 | - | VdWContact |
| ASP 7 | NTc.Cm34 | LYS 50 | 1.31x31 | Anionic |
| ASP 7 | NTc.Cm34 | LYS 50 | 1.31x31 | VdWContact |
| ASP 7 | NTc.Cm34 | ARG 201 | - | Anionic |
| ASP 7 | NTc.Cm34 | ARG 201 | - | HBAcceptor |
| ASP 7 | NTc.Cm34 | ARG 201 | - | VdWContact |
| LEU 8 | NTc.Cm33 | THR 203 | 45.51x51 | Hydrophobic |
| LEU 8 | NTc.Cm33 | THR 203 | 45.51x51 | VdWContact |
| GLN 9 | NTc.Cm32 | ASN 297 | 7.28x27 | VdWContact |
| GLN 9 | NTc.Cm32 | GLY 298 | 7.29x28 | HBDonor |
| GLN 9 | NTc.Cm32 | GLY 298 | 7.29x28 | VdWContact |
| GLN 9 | NTc.Cm32 | PRO 301 | 7.32x31 | Hydrophobic |
| GLN 9 | NTc.Cm32 | PRO 301 | 7.32x31 | VdWContact |
| CYS 10 | NTc.Cm31 | ASN 297 | 7.28x27 | HBAcceptor |
| CYS 10 | NTc.Cm31 | ASN 297 | 7.28x27 | VdWContact |
| LEU 11 | NTc.Cm30 | LEU 37 | - | Hydrophobic |
| LEU 11 | NTc.Cm30 | LEU 37 | - | VdWContact |
| LEU 11 | NTc.Cm30 | CYS 38 | - | HBAcceptor |
| LEU 11 | NTc.Cm30 | CYS 38 | - | VdWContact |
| LEU 11 | NTc.Cm30 | ALA 40 | - | Hydrophobic |
| LEU 11 | NTc.Cm30 | HIS 195 | - | Hydrophobic |
| VAL 13 | NTc.Cm28 | HIS 36 | - | HBDonor |
| VAL 13 | NTc.Cm28 | HIS 36 | - | VdWContact |
| VAL 13 | NTc.Cm28 | CYS 38 | - | VdWContact |
| VAL 13 | NTc.Cm28 | ASN 292 | - | Hydrophobic |
| VAL 13 | NTc.Cm28 | ASN 292 | - | VdWContact |
| VAL 13 | NTc.Cm28 | THR 293 | 7.24x23 | VdWContact |
| VAL 13 | NTc.Cm28 | ASN 297 | 7.28x27 | Hydrophobic |
| LYS 14 | NTc.Cm27 | HIS 36 | - | Hydrophobic |
| LYS 14 | NTc.Cm27 | HIS 36 | - | VdWContact |
| THR 16 | NTc.Cm25 | VAL 33 | - | Hydrophobic |
| THR 16 | NTc.Cm25 | VAL 33 | - | VdWContact |
| GLN 18 | NTc.Cm23 | SER 31 | - | HBAcceptor |
| GLN 18 | NTc.Cm23 | SER 31 | - | VdWContact |
| VAL 19 | NTc.Cm22 | VAL 33 | - | Hydrophobic |
| ARG 20 | NTc.Cm21 | TYR 27 | - | HBDonor |
| ARG 20 | NTc.Cm21 | TYR 27 | - | VdWContact |
| ARG 20 | NTc.Cm21 | ASN 28 | - | HBDonor |
| ARG 20 | NTc.Cm21 | ASN 28 | - | VdWContact |
| PRO 21 | NTc.Cm20 | PHE 18 | - | Hydrophobic |
| PRO 21 | NTc.Cm20 | PHE 18 | - | VdWContact |
| PRO 21 | NTc.Cm20 | LEU 21 | - | Hydrophobic |
| PRO 21 | NTc.Cm20 | LEU 21 | - | VdWContact |
| ARG 22 | NTc.Cm19 | TRP 19 | - | VdWContact |
| ARG 22 | NTc.Cm19 | ASP 22 | - | Cationic |
| ARG 22 | NTc.Cm19 | ASP 22 | - | HBDonor |
| ARG 22 | NTc.Cm19 | ASP 22 | - | VdWContact |
| ILE 24 | NTc.Cm17 | LEU 11 | - | Hydrophobic |
| ILE 24 | NTc.Cm17 | LEU 11 | - | VdWContact |
| ILE 24 | NTc.Cm17 | PHE 18 | - | Hydrophobic |
| ILE 24 | NTc.Cm17 | PHE 18 | - | VdWContact |
| THR 25 | NTc.Cm16 | LEU 11 | - | VdWContact |
| LEU 27 | NTc.Cm14 | GLU 8 | - | VdWContact |
| LEU 27 | NTc.Cm14 | MET 9 | - | HBAcceptor |
| LEU 27 | NTc.Cm14 | MET 9 | - | VdWContact |
| LEU 27 | NTc.Cm14 | PHE 18 | - | Hydrophobic |
| GLU 28 | NTc.Cm13 | THR 6 | - | Hydrophobic |
| GLU 28 | NTc.Cm13 | THR 6 | - | VdWContact |
| GLU 28 | NTc.Cm13 | LEU 7 | - | VdWContact |
| GLU 28 | NTc.Cm13 | GLU 8 | - | Hydrophobic |
| GLU 28 | NTc.Cm13 | HIS 194 | - | HBAcceptor |
| GLU 28 | NTc.Cm13 | HIS 194 | - | VdWContact |
| VAL 29 | NTc.Cm12 | LEU 5 | - | VdWContact |
| VAL 29 | NTc.Cm12 | THR 6 | - | VdWContact |
| VAL 29 | NTc.Cm12 | LEU 7 | - | HBAcceptor |
| VAL 29 | NTc.Cm12 | LEU 7 | - | HBDonor |
| VAL 29 | NTc.Cm12 | LEU 7 | - | Hydrophobic |
| VAL 29 | NTc.Cm12 | LEU 7 | - | VdWContact |
| ILE 30 | NTc.Cm11 | LEU 5 | - | Hydrophobic |
| ILE 30 | NTc.Cm11 | LEU 5 | - | VdWContact |
| ILE 30 | NTc.Cm11 | HIS 194 | - | Hydrophobic |
| ILE 30 | NTc.Cm11 | HIS 194 | - | VdWContact |
| LYS 31 | NTc.Cm10 | LEU 5 | - | HBDonor |
| LYS 31 | NTc.Cm10 | LEU 5 | - | Hydrophobic |
| LYS 31 | NTc.Cm10 | LEU 5 | - | VdWContact |
| GLY 33 | NTc.Cm8 | GLN 206 | - | VdWContact |
| PRO 34 | NTc.Cm7 | SER 191 | - | VdWContact |
| PRO 34 | NTc.Cm7 | THR 203 | 45.51x51 | Hydrophobic |
| PRO 34 | NTc.Cm7 | THR 203 | 45.51x51 | VdWContact |
| PRO 34 | NTc.Cm7 | PHE 204 | 45.52x52 | VdWContact |
| PRO 34 | NTc.Cm7 | ARG 286 | 6.62x62 | HBAcceptor |
| PRO 34 | NTc.Cm7 | ARG 286 | 6.62x62 | VdWContact |
| HIS 35 | NTc.Cm6 | LEU 5 | - | Hydrophobic |
| HIS 35 | NTc.Cm6 | LEU 5 | - | VdWContact |
| PRO 37 | NTc.Cm4 | ARG 286 | 6.62x62 | Hydrophobic |
| ILE 42 | CX.4 | LEU 37 | - | Hydrophobic |
| ILE 42 | CX.4 | LEU 37 | - | VdWContact |
| LYS 50 | cxb1.11 | ASN 35 | - | VdWContact |
| LYS 50 | cxb1.11 | LEU 37 | - | Hydrophobic |
| ILE 51 | cxb1.14 | VAL 33 | - | Hydrophobic |
| ILE 51 | cxb1.14 | VAL 33 | - | VdWContact |
| CYS 52 | cxb1.15 | HIS 36 | - | Hydrophobic |
| LEU 59 | B1.6 | LEU 21 | - | Hydrophobic |
| LEU 59 | B1.6 | LEU 21 | - | VdWContact |
| LEU 59 | B1.6 | ASP 25 | - | Hydrophobic |
| ILE 63 | b1b2.7 | LEU 14 | - | Hydrophobic |
| ILE 63 | b1b2.7 | LEU 17 | - | Hydrophobic |
| ILE 63 | b1b2.7 | LEU 17 | - | VdWContact |
| ILE 63 | b1b2.7 | PHE 18 | - | Hydrophobic |
| ILE 63 | b1b2.7 | LEU 21 | - | Hydrophobic |
| LYS 66 | b1b2.10 | LEU 17 | - | Hydrophobic |
| LYS 66 | b1b2.10 | LEU 17 | - | VdWContact |
| LEU 67 | b1b2.12 | LEU 7 | - | Hydrophobic |
| LEU 67 | b1b2.12 | MET 9 | - | Hydrophobic |
| LEU 67 | b1b2.12 | MET 9 | - | VdWContact |
| LEU 68 | b1b2.13 | LEU 7 | - | Hydrophobic |
