Predicted complex interactions
CXCL5_HUMAN + CXCR5
SUMMARY
- Chemokine
- CXCL5_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR5 View partner entry
- Partner description
- UniProt: P32302; Gene: cxcr5_human; Family: Chemokine
- Interactions detected
- 142
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm48 | ARG 219 | 5.39x40 | VdWContact |
| ALA 1 | NTc.Cm48 | TYR 275 | 6.51x51 | HBAcceptor |
| ALA 1 | NTc.Cm48 | TYR 275 | 6.51x51 | Hydrophobic |
| ALA 1 | NTc.Cm48 | TYR 275 | 6.51x51 | VdWContact |
| ALA 1 | NTc.Cm48 | ILE 279 | 6.55x55 | Hydrophobic |
| ALA 1 | NTc.Cm48 | ILE 304 | 7.35x34 | Hydrophobic |
| GLY 2 | NTc.Cm47 | HIS 129 | 3.32x32 | VdWContact |
| GLY 2 | NTc.Cm47 | GLU 308 | 7.39x38 | VdWContact |
| PRO 3 | NTc.Cm46 | ILE 103 | 2.56x56 | Hydrophobic |
| PRO 3 | NTc.Cm46 | ALA 107 | 2.60x60 | Hydrophobic |
| PRO 3 | NTc.Cm46 | HIS 129 | 3.32x32 | Hydrophobic |
| PRO 3 | NTc.Cm46 | HIS 129 | 3.32x32 | VdWContact |
| PRO 3 | NTc.Cm46 | GLU 308 | 7.39x38 | VdWContact |
| ALA 4 | NTc.Cm45 | ILE 126 | 3.29x29 | Hydrophobic |
| ALA 5 | NTc.Cm44 | ILE 304 | 7.35x34 | Hydrophobic |
| ALA 6 | NTc.Cm43 | LYS 50 | 1.31x31 | HBAcceptor |
| ALA 6 | NTc.Cm43 | LYS 50 | 1.31x31 | VdWContact |
| ALA 6 | NTc.Cm43 | TYR 58 | 1.39x39 | Hydrophobic |
| ALA 6 | NTc.Cm43 | TYR 58 | 1.39x39 | VdWContact |
| ALA 6 | NTc.Cm43 | THR 305 | 7.36x35 | Hydrophobic |
| ALA 6 | NTc.Cm43 | THR 305 | 7.36x35 | VdWContact |
| ALA 6 | NTc.Cm43 | GLU 308 | 7.39x38 | VdWContact |
| VAL 7 | NTc.Cm42 | LYS 50 | 1.31x31 | VdWContact |
| VAL 7 | NTc.Cm42 | VAL 54 | 1.35x35 | Hydrophobic |
| VAL 7 | NTc.Cm42 | GLY 111 | 2.64x64 | VdWContact |
| LEU 8 | NTc.Cm41 | GLU 110 | 2.63x63 | Hydrophobic |
| LEU 8 | NTc.Cm41 | GLU 110 | 2.63x63 | VdWContact |
| LEU 8 | NTc.Cm41 | ARG 201 | - | Hydrophobic |
| LEU 8 | NTc.Cm41 | ARG 201 | - | VdWContact |
| LEU 8 | NTc.Cm41 | CYS 202 | 45.50x50 | VdWContact |
| LEU 8 | NTc.Cm41 | THR 203 | 45.51x51 | Hydrophobic |
| ARG 9 | NTc.Cm40 | ALA 40 | - | VdWContact |
| ARG 9 | NTc.Cm40 | THR 41 | - | VdWContact |
| ARG 9 | NTc.Cm40 | GLU 42 | - | Cationic |
| ARG 9 | NTc.Cm40 | GLU 42 | - | Hydrophobic |
| ARG 9 | NTc.Cm40 | GLU 42 | - | VdWContact |
| ARG 9 | NTc.Cm40 | ARG 201 | - | HBAcceptor |
| ARG 9 | NTc.Cm40 | ARG 201 | - | VdWContact |
| GLU 10 | NTc.Cm39 | ARG 219 | 5.39x40 | Anionic |
| GLU 10 | NTc.Cm39 | ARG 219 | 5.39x40 | VdWContact |
| GLU 10 | NTc.Cm39 | ARG 286 | 6.62x62 | Anionic |
| GLU 10 | NTc.Cm39 | ARG 286 | 6.62x62 | HBAcceptor |
| GLU 10 | NTc.Cm39 | ARG 286 | 6.62x62 | VdWContact |
| LEU 11 | NTc.Cm38 | GLY 193 | - | VdWContact |
| ARG 12 | NTc.Cm37 | ASP 282 | 6.58x58 | Cationic |
| ARG 12 | NTc.Cm37 | ASP 282 | 6.58x58 | VdWContact |
| ARG 12 | NTc.Cm37 | ASN 297 | 7.28x27 | HBDonor |
| ARG 12 | NTc.Cm37 | ASN 297 | 7.28x27 | VdWContact |
| ARG 12 | NTc.Cm37 | LEU 300 | 7.31x30 | VdWContact |
| CYS 13 | NTc.Cm36 | ASN 297 | 7.28x27 | HBAcceptor |
| CYS 13 | NTc.Cm36 | ASN 297 | 7.28x27 | VdWContact |
| VAL 14 | NTc.Cm35 | LEU 37 | - | Hydrophobic |
| VAL 14 | NTc.Cm35 | LEU 37 | - | VdWContact |
| VAL 14 | NTc.Cm35 | CYS 38 | - | HBAcceptor |
| VAL 14 | NTc.Cm35 | CYS 38 | - | VdWContact |
| VAL 14 | NTc.Cm35 | ALA 40 | - | Hydrophobic |
| VAL 14 | NTc.Cm35 | HIS 195 | - | Hydrophobic |
| LEU 16 | NTc.Cm33 | CYS 38 | - | Hydrophobic |
| LEU 16 | NTc.Cm33 | CYS 38 | - | VdWContact |
| LEU 16 | NTc.Cm33 | ASN 292 | - | Hydrophobic |
| LEU 16 | NTc.Cm33 | ASN 292 | - | VdWContact |
| LEU 16 | NTc.Cm33 | ASN 297 | 7.28x27 | Hydrophobic |
| GLN 17 | NTc.Cm32 | HIS 36 | - | Hydrophobic |
| GLN 17 | NTc.Cm32 | HIS 36 | - | VdWContact |
| THR 19 | NTc.Cm30 | VAL 33 | - | Hydrophobic |
| GLN 20 | NTc.Cm29 | TYR 27 | - | HBAcceptor |
| GLN 20 | NTc.Cm29 | TYR 27 | - | VdWContact |
| GLY 21 | NTc.Cm28 | TYR 27 | - | VdWContact |
| VAL 22 | NTc.Cm27 | LEU 32 | - | Hydrophobic |
| HIS 23 | NTc.Cm26 | ASP 22 | - | VdWContact |
| PRO 24 | NTc.Cm25 | LEU 11 | - | VdWContact |
| PRO 24 | NTc.Cm25 | PHE 18 | - | Hydrophobic |
| PRO 24 | NTc.Cm25 | PHE 18 | - | VdWContact |
| LYS 25 | NTc.Cm24 | PHE 18 | - | Hydrophobic |
| MET 26 | NTc.Cm23 | LEU 32 | - | Hydrophobic |
| MET 26 | NTc.Cm23 | LEU 32 | - | VdWContact |
| ILE 27 | NTc.Cm22 | MET 9 | - | Hydrophobic |
| ILE 27 | NTc.Cm22 | MET 9 | - | VdWContact |
| ILE 27 | NTc.Cm22 | LEU 11 | - | VdWContact |
| ASN 29 | NTc.Cm20 | LEU 7 | - | VdWContact |
| LEU 30 | NTc.Cm19 | LEU 7 | - | HBAcceptor |
| LEU 30 | NTc.Cm19 | LEU 7 | - | HBDonor |
| LEU 30 | NTc.Cm19 | LEU 7 | - | Hydrophobic |
| LEU 30 | NTc.Cm19 | LEU 7 | - | VdWContact |
| LEU 30 | NTc.Cm19 | MET 9 | - | Hydrophobic |
| LEU 30 | NTc.Cm19 | MET 9 | - | VdWContact |
| GLN 31 | NTc.Cm18 | THR 6 | - | Hydrophobic |
| GLN 31 | NTc.Cm18 | THR 6 | - | VdWContact |
| VAL 32 | NTc.Cm17 | PRO 4 | - | VdWContact |
| VAL 32 | NTc.Cm17 | LEU 5 | - | HBAcceptor |
| VAL 32 | NTc.Cm17 | LEU 5 | - | HBDonor |
| VAL 32 | NTc.Cm17 | LEU 5 | - | Hydrophobic |
| VAL 32 | NTc.Cm17 | LEU 5 | - | VdWContact |
| VAL 32 | NTc.Cm17 | LEU 7 | - | Hydrophobic |
| PHE 33 | NTc.Cm16 | PRO 4 | - | Hydrophobic |
| PHE 33 | NTc.Cm16 | PRO 4 | - | VdWContact |
| PHE 33 | NTc.Cm16 | HIS 194 | - | Hydrophobic |
| PHE 33 | NTc.Cm16 | HIS 194 | - | VdWContact |
| PHE 33 | NTc.Cm16 | HIS 195 | - | Hydrophobic |
| ILE 35 | NTc.Cm14 | ASN 2 | - | HBAcceptor |
| ILE 35 | NTc.Cm14 | ASN 2 | - | VdWContact |
| ILE 35 | NTc.Cm14 | GLU 207 | - | VdWContact |
| GLY 36 | NTc.Cm13 | GLN 206 | - | VdWContact |
| PRO 37 | NTc.Cm12 | SER 191 | - | VdWContact |
| PRO 37 | NTc.Cm12 | SER 205 | - | VdWContact |
| PRO 37 | NTc.Cm12 | GLN 206 | - | VdWContact |
| PRO 37 | NTc.Cm12 | GLU 207 | - | Hydrophobic |
| PRO 37 | NTc.Cm12 | GLU 207 | - | VdWContact |
| GLN 38 | NTc.Cm11 | HIS 194 | - | VdWContact |
| LYS 41 | NTc.Cm8 | LYS 288 | 6.64x64 | VdWContact |
| VAL 45 | NTc.Cm4 | LEU 37 | - | Hydrophobic |
| VAL 45 | NTc.Cm4 | LEU 37 | - | VdWContact |
| LEU 48 | NTc.Cm1 | LEU 32 | - | Hydrophobic |
| LYS 49 | CX.1 | LEU 11 | - | VdWContact |
| GLU 53 | cxb1.2 | LEU 37 | - | Hydrophobic |
| GLU 53 | cxb1.2 | LEU 37 | - | VdWContact |
| ILE 54 | cxb1.5 | LEU 32 | - | Hydrophobic |
| CYS 55 | cxb1.6 | LEU 37 | - | VdWContact |
| ALA 60 | cxb1.15 | TYR 27 | - | VdWContact |
| PHE 62 | B1.1 | LEU 21 | - | Hydrophobic |
| PHE 62 | B1.1 | LEU 21 | - | VdWContact |
| PHE 62 | B1.1 | TYR 27 | - | Hydrophobic |
| PHE 62 | B1.1 | TYR 27 | - | VdWContact |
| LYS 65 | B1.4 | LEU 17 | - | Hydrophobic |
| LYS 65 | B1.4 | LEU 21 | - | Hydrophobic |
| VAL 66 | B1.5 | MET 9 | - | Hydrophobic |
| VAL 66 | B1.5 | MET 9 | - | VdWContact |
| VAL 66 | B1.5 | LEU 14 | - | Hydrophobic |
| VAL 66 | B1.5 | LEU 17 | - | Hydrophobic |
| ILE 67 | B1.6 | LEU 7 | - | Hydrophobic |
| LYS 69 | b1b2.4 | ASN 13 | - | HBDonor |
| LYS 69 | b1b2.4 | ASN 13 | - | VdWContact |
| LYS 69 | b1b2.4 | LEU 14 | - | Hydrophobic |
| LYS 69 | b1b2.4 | LEU 14 | - | VdWContact |
| LYS 69 | b1b2.4 | ASP 16 | - | Cationic |
| LYS 69 | b1b2.4 | ASP 16 | - | VdWContact |
| LYS 69 | b1b2.4 | LEU 17 | - | HBDonor |
| LYS 69 | b1b2.4 | LEU 17 | - | Hydrophobic |
| LYS 69 | b1b2.4 | LEU 17 | - | VdWContact |
| ILE 70 | b1b2.6 | LEU 7 | - | Hydrophobic |
| ILE 70 | b1b2.6 | LEU 7 | - | VdWContact |
| ILE 70 | b1b2.6 | LEU 14 | - | Hydrophobic |
