Predicted complex interactions
CXCL6_HUMAN + CXCR5
SUMMARY
- Chemokine
- CXCL6_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR5 View partner entry
- Partner description
- UniProt: P32302; Gene: cxcr5_human; Family: Chemokine
- Interactions detected
- 164
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm48 | ALA 40 | - | VdWContact |
| GLY 1 | NTc.Cm48 | THR 41 | - | VdWContact |
| GLY 1 | NTc.Cm48 | GLU 42 | - | VdWContact |
| GLY 1 | NTc.Cm48 | ARG 201 | - | HBAcceptor |
| GLY 1 | NTc.Cm48 | ARG 201 | - | VdWContact |
| PRO 2 | NTc.Cm47 | GLU 42 | - | VdWContact |
| PRO 2 | NTc.Cm47 | LYS 50 | 1.31x31 | HBAcceptor |
| PRO 2 | NTc.Cm47 | LYS 50 | 1.31x31 | Hydrophobic |
| PRO 2 | NTc.Cm47 | LYS 50 | 1.31x31 | VdWContact |
| PRO 2 | NTc.Cm47 | ARG 201 | - | VdWContact |
| VAL 3 | NTc.Cm46 | LYS 50 | 1.31x31 | HBAcceptor |
| VAL 3 | NTc.Cm46 | LYS 50 | 1.31x31 | VdWContact |
| VAL 3 | NTc.Cm46 | ARG 201 | - | VdWContact |
| VAL 3 | NTc.Cm46 | PRO 301 | 7.32x31 | Hydrophobic |
| SER 4 | NTc.Cm45 | ILE 304 | 7.35x34 | VdWContact |
| SER 4 | NTc.Cm45 | THR 305 | 7.36x35 | VdWContact |
| SER 4 | NTc.Cm45 | GLU 308 | 7.39x38 | HBDonor |
| SER 4 | NTc.Cm45 | GLU 308 | 7.39x38 | VdWContact |
| ALA 5 | NTc.Cm44 | VAL 54 | 1.35x35 | Hydrophobic |
| ALA 5 | NTc.Cm44 | TYR 58 | 1.39x39 | Hydrophobic |
| ALA 5 | NTc.Cm44 | TYR 58 | 1.39x39 | VdWContact |
| ALA 5 | NTc.Cm44 | ALA 107 | 2.60x60 | VdWContact |
| ALA 5 | NTc.Cm44 | THR 305 | 7.36x35 | Hydrophobic |
| VAL 6 | NTc.Cm43 | TYR 58 | 1.39x39 | Hydrophobic |
| VAL 6 | NTc.Cm43 | ILE 103 | 2.56x56 | Hydrophobic |
| VAL 6 | NTc.Cm43 | ALA 107 | 2.60x60 | Hydrophobic |
| VAL 6 | NTc.Cm43 | HIS 129 | 3.32x32 | Hydrophobic |
| VAL 6 | NTc.Cm43 | HIS 129 | 3.32x32 | VdWContact |
| VAL 6 | NTc.Cm43 | GLU 308 | 7.39x38 | VdWContact |
| VAL 6 | NTc.Cm43 | LEU 312 | 7.43x42 | Hydrophobic |
| LEU 7 | NTc.Cm42 | ILE 126 | 3.29x29 | Hydrophobic |
| LEU 7 | NTc.Cm42 | ILE 126 | 3.29x29 | VdWContact |
| LEU 7 | NTc.Cm42 | HIS 129 | 3.32x32 | Hydrophobic |
| LEU 7 | NTc.Cm42 | TYR 275 | 6.51x51 | VdWContact |
| THR 8 | NTc.Cm41 | ARG 201 | - | VdWContact |
| THR 8 | NTc.Cm41 | THR 203 | 45.51x51 | VdWContact |
| GLU 9 | NTc.Cm40 | TRP 215 | 5.35x36 | HBAcceptor |
| GLU 9 | NTc.Cm40 | TRP 215 | 5.35x36 | VdWContact |
| GLU 9 | NTc.Cm40 | ARG 219 | 5.39x40 | Anionic |
| GLU 9 | NTc.Cm40 | ARG 219 | 5.39x40 | HBAcceptor |
| GLU 9 | NTc.Cm40 | ARG 219 | 5.39x40 | VdWContact |
| GLU 9 | NTc.Cm40 | ASP 282 | 6.58x58 | VdWContact |
| GLU 9 | NTc.Cm40 | ARG 286 | 6.62x62 | Anionic |
| GLU 9 | NTc.Cm40 | ARG 286 | 6.62x62 | HBAcceptor |
| GLU 9 | NTc.Cm40 | ARG 286 | 6.62x62 | VdWContact |
| LEU 10 | NTc.Cm39 | THR 203 | 45.51x51 | Hydrophobic |
| LEU 10 | NTc.Cm39 | THR 203 | 45.51x51 | VdWContact |
| LEU 10 | NTc.Cm39 | ARG 286 | 6.62x62 | HBAcceptor |
| LEU 10 | NTc.Cm39 | ARG 286 | 6.62x62 | VdWContact |
| ARG 11 | NTc.Cm38 | ASP 282 | 6.58x58 | Cationic |
| ARG 11 | NTc.Cm38 | ASP 282 | 6.58x58 | HBDonor |
| ARG 11 | NTc.Cm38 | ASP 282 | 6.58x58 | VdWContact |
| ARG 11 | NTc.Cm38 | ASN 297 | 7.28x27 | HBDonor |
| ARG 11 | NTc.Cm38 | ASN 297 | 7.28x27 | VdWContact |
| ARG 11 | NTc.Cm38 | LEU 300 | 7.31x30 | VdWContact |
| ARG 11 | NTc.Cm38 | PRO 301 | 7.32x31 | VdWContact |
| CYS 12 | NTc.Cm37 | ASN 297 | 7.28x27 | HBAcceptor |
| CYS 12 | NTc.Cm37 | ASN 297 | 7.28x27 | VdWContact |
| THR 13 | NTc.Cm36 | LEU 37 | - | Hydrophobic |
| THR 13 | NTc.Cm36 | CYS 38 | - | HBAcceptor |
| THR 13 | NTc.Cm36 | CYS 38 | - | VdWContact |
| LEU 15 | NTc.Cm34 | CYS 38 | - | Hydrophobic |
| LEU 15 | NTc.Cm34 | CYS 38 | - | VdWContact |
| LEU 15 | NTc.Cm34 | ASN 292 | - | Hydrophobic |
| LEU 15 | NTc.Cm34 | ASN 292 | - | VdWContact |
| LEU 15 | NTc.Cm34 | ASN 297 | 7.28x27 | Hydrophobic |
| LEU 15 | NTc.Cm34 | ASN 297 | 7.28x27 | VdWContact |
| ARG 16 | NTc.Cm33 | GLU 34 | - | Cationic |
| ARG 16 | NTc.Cm33 | HIS 36 | - | Hydrophobic |
| ARG 16 | NTc.Cm33 | HIS 36 | - | VdWContact |
| THR 18 | NTc.Cm31 | VAL 33 | - | Hydrophobic |
| LEU 19 | NTc.Cm30 | TYR 27 | - | HBAcceptor |
| LEU 19 | NTc.Cm30 | TYR 27 | - | VdWContact |
| ARG 20 | NTc.Cm29 | TYR 27 | - | Hydrophobic |
| ARG 20 | NTc.Cm29 | TYR 27 | - | VdWContact |
| ARG 20 | NTc.Cm29 | ASP 29 | - | Cationic |
| VAL 21 | NTc.Cm28 | TYR 27 | - | VdWContact |
| VAL 21 | NTc.Cm28 | VAL 33 | - | Hydrophobic |
| PRO 23 | NTc.Cm26 | PHE 18 | - | Hydrophobic |
| PRO 23 | NTc.Cm26 | PHE 18 | - | VdWContact |
| LYS 24 | NTc.Cm25 | PHE 18 | - | Hydrophobic |
| LYS 24 | NTc.Cm25 | ASP 22 | - | Cationic |
| LYS 24 | NTc.Cm25 | ASP 22 | - | HBDonor |
| LYS 24 | NTc.Cm25 | ASP 22 | - | VdWContact |
| ILE 26 | NTc.Cm23 | LEU 11 | - | Hydrophobic |
| GLY 27 | NTc.Cm22 | LEU 11 | - | HBAcceptor |
| GLY 27 | NTc.Cm22 | LEU 11 | - | VdWContact |
| LYS 28 | NTc.Cm21 | GLU 8 | - | Cationic |
| LYS 28 | NTc.Cm21 | GLU 8 | - | HBDonor |
| LYS 28 | NTc.Cm21 | GLU 8 | - | Hydrophobic |
| LYS 28 | NTc.Cm21 | GLU 8 | - | VdWContact |
| LYS 28 | NTc.Cm21 | MET 9 | - | VdWContact |
| LYS 28 | NTc.Cm21 | ASP 10 | - | VdWContact |
| LEU 29 | NTc.Cm20 | GLU 8 | - | VdWContact |
| LEU 29 | NTc.Cm20 | MET 9 | - | HBAcceptor |
| LEU 29 | NTc.Cm20 | MET 9 | - | HBDonor |
| LEU 29 | NTc.Cm20 | MET 9 | - | Hydrophobic |
| LEU 29 | NTc.Cm20 | MET 9 | - | VdWContact |
| LEU 29 | NTc.Cm20 | LEU 11 | - | Hydrophobic |
| GLN 30 | NTc.Cm19 | LEU 7 | - | VdWContact |
| GLN 30 | NTc.Cm19 | GLU 8 | - | HBDonor |
| GLN 30 | NTc.Cm19 | GLU 8 | - | Hydrophobic |
| GLN 30 | NTc.Cm19 | GLU 8 | - | VdWContact |
| VAL 31 | NTc.Cm18 | TYR 3 | - | Hydrophobic |
| VAL 31 | NTc.Cm18 | TYR 3 | - | VdWContact |
| VAL 31 | NTc.Cm18 | THR 6 | - | VdWContact |
| VAL 31 | NTc.Cm18 | LEU 7 | - | HBAcceptor |
| VAL 31 | NTc.Cm18 | LEU 7 | - | HBDonor |
| VAL 31 | NTc.Cm18 | LEU 7 | - | Hydrophobic |
| VAL 31 | NTc.Cm18 | LEU 7 | - | VdWContact |
| PHE 32 | NTc.Cm17 | THR 6 | - | Hydrophobic |
| PHE 32 | NTc.Cm17 | HIS 194 | - | Hydrophobic |
| PHE 32 | NTc.Cm17 | HIS 194 | - | VdWContact |
| PHE 32 | NTc.Cm17 | HIS 195 | - | Hydrophobic |
| PHE 32 | NTc.Cm17 | HIS 195 | - | VdWContact |
| PRO 33 | NTc.Cm16 | TYR 3 | - | Hydrophobic |
| PRO 33 | NTc.Cm16 | TYR 3 | - | VdWContact |
| PRO 33 | NTc.Cm16 | HIS 194 | - | Hydrophobic |
| PRO 33 | NTc.Cm16 | HIS 194 | - | VdWContact |
| GLY 35 | NTc.Cm14 | GLU 207 | - | VdWContact |
| PRO 36 | NTc.Cm13 | SER 191 | - | VdWContact |
| PRO 36 | NTc.Cm13 | GLN 206 | - | VdWContact |
| PRO 36 | NTc.Cm13 | GLU 207 | - | Hydrophobic |
| PRO 36 | NTc.Cm13 | GLU 207 | - | VdWContact |
| GLN 37 | NTc.Cm12 | GLY 193 | - | VdWContact |
| VAL 41 | NTc.Cm8 | TYR 3 | - | Hydrophobic |
| VAL 44 | NTc.Cm5 | LEU 37 | - | Hydrophobic |
| VAL 44 | NTc.Cm5 | LEU 37 | - | VdWContact |
| LYS 48 | NTc.Cm1 | GLU 12 | - | VdWContact |
| LYS 51 | CX.5 | ASN 35 | - | VdWContact |
| GLN 52 | cxb1.1 | ASN 35 | - | HBDonor |
| GLN 52 | cxb1.1 | LEU 37 | - | Hydrophobic |
| GLN 52 | cxb1.1 | LEU 37 | - | VdWContact |
| VAL 53 | cxb1.2 | VAL 33 | - | Hydrophobic |
| VAL 53 | cxb1.2 | VAL 33 | - | VdWContact |
| CYS 54 | cxb1.5 | LEU 37 | - | VdWContact |
| GLU 58 | cxb1.11 | MET 1 | - | Anionic |
| GLU 58 | cxb1.11 | MET 1 | - | HBAcceptor |
| PHE 61 | cxb1.16 | LEU 21 | - | Hydrophobic |
| PHE 61 | cxb1.16 | LEU 21 | - | VdWContact |
| PHE 61 | cxb1.16 | TYR 27 | - | Hydrophobic |
| LYS 63 | B1.2 | MET 1 | - | Hydrophobic |
| LYS 64 | B1.3 | LEU 21 | - | Hydrophobic |
| LYS 64 | B1.3 | LEU 24 | - | Hydrophobic |
| LYS 64 | B1.3 | LEU 24 | - | VdWContact |
| VAL 65 | B1.4 | MET 9 | - | Hydrophobic |
| VAL 65 | B1.4 | MET 9 | - | VdWContact |
| VAL 65 | B1.4 | LEU 11 | - | Hydrophobic |
| VAL 65 | B1.4 | LEU 17 | - | Hydrophobic |
| VAL 65 | B1.4 | LEU 17 | - | VdWContact |
| VAL 65 | B1.4 | LEU 21 | - | Hydrophobic |
| ILE 66 | B1.5 | TYR 3 | - | Hydrophobic |
| ILE 66 | B1.5 | TYR 3 | - | VdWContact |
| ILE 66 | B1.5 | MET 9 | - | Hydrophobic |
| LYS 68 | B1.7 | LEU 17 | - | Hydrophobic |
| LYS 68 | B1.7 | LEU 17 | - | VdWContact |
| LYS 68 | B1.7 | GLU 20 | - | Cationic |
| LYS 68 | B1.7 | GLU 20 | - | HBDonor |
| LYS 68 | B1.7 | GLU 20 | - | VdWContact |
| ILE 69 | b1b2.4 | MET 9 | - | Hydrophobic |
| ILE 69 | b1b2.4 | MET 9 | - | VdWContact |
| ILE 69 | b1b2.4 | LEU 14 | - | Hydrophobic |
| ILE 69 | b1b2.4 | LEU 14 | - | VdWContact |
| LEU 70 | b1b2.6 | TYR 3 | - | Hydrophobic |
