Predicted complex interactions
CXCL7_HUMAN + CXCR5
SUMMARY
- Chemokine
- CXCL7_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR5 View partner entry
- Partner description
- UniProt: P32302; Gene: cxcr5_human; Family: Chemokine
- Interactions detected
- 133
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 21 | NTc.Cm42 | THR 41 | - | VdWContact |
| LEU 23 | NTc.Cm40 | SER 198 | - | VdWContact |
| LEU 23 | NTc.Cm40 | LEU 199 | - | Hydrophobic |
| LEU 23 | NTc.Cm40 | ARG 201 | - | VdWContact |
| TYR 24 | NTc.Cm39 | ALA 47 | - | Hydrophobic |
| TYR 24 | NTc.Cm39 | GLY 111 | 2.64x64 | VdWContact |
| TYR 24 | NTc.Cm39 | ARG 201 | - | VdWContact |
| ALA 25 | NTc.Cm38 | ALA 40 | - | Hydrophobic |
| ALA 25 | NTc.Cm38 | THR 41 | - | Hydrophobic |
| ALA 25 | NTc.Cm38 | THR 41 | - | VdWContact |
| GLU 26 | NTc.Cm37 | ALA 40 | - | HBDonor |
| GLU 26 | NTc.Cm37 | ALA 40 | - | VdWContact |
| GLU 26 | NTc.Cm37 | LYS 50 | 1.31x31 | Anionic |
| GLU 26 | NTc.Cm37 | PRO 301 | 7.32x31 | Hydrophobic |
| GLU 26 | NTc.Cm37 | PRO 301 | 7.32x31 | VdWContact |
| ARG 28 | NTc.Cm35 | ASP 282 | 6.58x58 | Cationic |
| ARG 28 | NTc.Cm35 | ASP 282 | 6.58x58 | HBDonor |
| ARG 28 | NTc.Cm35 | ASP 282 | 6.58x58 | VdWContact |
| ARG 28 | NTc.Cm35 | LEU 300 | 7.31x30 | VdWContact |
| ARG 28 | NTc.Cm35 | PRO 301 | 7.32x31 | VdWContact |
| ARG 28 | NTc.Cm35 | ILE 304 | 7.35x34 | VdWContact |
| CYS 29 | NTc.Cm34 | ASN 297 | 7.28x27 | HBAcceptor |
| CYS 29 | NTc.Cm34 | ASN 297 | 7.28x27 | VdWContact |
| MET 30 | NTc.Cm33 | LEU 37 | - | Hydrophobic |
| MET 30 | NTc.Cm33 | CYS 38 | - | HBAcceptor |
| MET 30 | NTc.Cm33 | CYS 38 | - | VdWContact |
| MET 30 | NTc.Cm33 | ALA 40 | - | Hydrophobic |
| MET 30 | NTc.Cm33 | ALA 40 | - | VdWContact |
| MET 30 | NTc.Cm33 | HIS 195 | - | Hydrophobic |
| ILE 32 | NTc.Cm31 | CYS 38 | - | Hydrophobic |
| ILE 32 | NTc.Cm31 | CYS 38 | - | VdWContact |
| ILE 32 | NTc.Cm31 | ASN 292 | - | Hydrophobic |
| ILE 32 | NTc.Cm31 | ASN 292 | - | VdWContact |
| ILE 32 | NTc.Cm31 | ASN 297 | 7.28x27 | Hydrophobic |
| ILE 32 | NTc.Cm31 | ASN 297 | 7.28x27 | VdWContact |
| LYS 33 | NTc.Cm30 | HIS 36 | - | Hydrophobic |
| LYS 33 | NTc.Cm30 | HIS 36 | - | VdWContact |
| ILE 38 | NTc.Cm25 | TYR 27 | - | VdWContact |
| ILE 38 | NTc.Cm25 | VAL 33 | - | Hydrophobic |
| HIS 39 | NTc.Cm24 | ASP 22 | - | Hydrophobic |
| HIS 39 | NTc.Cm24 | ASP 22 | - | VdWContact |
| HIS 39 | NTc.Cm24 | TYR 27 | - | Hydrophobic |
| HIS 39 | NTc.Cm24 | TYR 27 | - | VdWContact |
| PRO 40 | NTc.Cm23 | PHE 18 | - | Hydrophobic |
| PRO 40 | NTc.Cm23 | PHE 18 | - | VdWContact |
| PRO 40 | NTc.Cm23 | LEU 21 | - | Hydrophobic |
| LYS 41 | NTc.Cm22 | PHE 18 | - | Hydrophobic |
| LYS 41 | NTc.Cm22 | ASP 22 | - | Cationic |
| LYS 41 | NTc.Cm22 | ASP 22 | - | HBDonor |
| LYS 41 | NTc.Cm22 | ASP 22 | - | VdWContact |
| ILE 43 | NTc.Cm20 | LEU 11 | - | Hydrophobic |
| ILE 43 | NTc.Cm20 | LEU 11 | - | VdWContact |
| GLN 44 | NTc.Cm19 | LEU 11 | - | HBAcceptor |
| GLN 44 | NTc.Cm19 | LEU 11 | - | VdWContact |
| SER 45 | NTc.Cm18 | MET 9 | - | VdWContact |
| SER 45 | NTc.Cm18 | ASP 10 | - | VdWContact |
| LEU 46 | NTc.Cm17 | GLU 8 | - | VdWContact |
| LEU 46 | NTc.Cm17 | MET 9 | - | HBAcceptor |
| LEU 46 | NTc.Cm17 | MET 9 | - | HBDonor |
| LEU 46 | NTc.Cm17 | MET 9 | - | Hydrophobic |
| LEU 46 | NTc.Cm17 | MET 9 | - | VdWContact |
| LEU 46 | NTc.Cm17 | LEU 11 | - | Hydrophobic |
| LEU 46 | NTc.Cm17 | LEU 11 | - | VdWContact |
| GLU 47 | NTc.Cm16 | LEU 7 | - | VdWContact |
| GLU 47 | NTc.Cm16 | GLU 8 | - | Hydrophobic |
| VAL 48 | NTc.Cm15 | TYR 3 | - | Hydrophobic |
| VAL 48 | NTc.Cm15 | THR 6 | - | VdWContact |
| VAL 48 | NTc.Cm15 | LEU 7 | - | HBAcceptor |
| VAL 48 | NTc.Cm15 | LEU 7 | - | HBDonor |
| VAL 48 | NTc.Cm15 | LEU 7 | - | Hydrophobic |
| VAL 48 | NTc.Cm15 | LEU 7 | - | VdWContact |
| ILE 49 | NTc.Cm14 | LEU 5 | - | VdWContact |
| ILE 49 | NTc.Cm14 | HIS 194 | - | Hydrophobic |
| ILE 49 | NTc.Cm14 | HIS 194 | - | VdWContact |
| ILE 49 | NTc.Cm14 | HIS 195 | - | Hydrophobic |
| GLY 50 | NTc.Cm13 | LEU 5 | - | HBDonor |
| GLY 50 | NTc.Cm13 | LEU 5 | - | VdWContact |
| GLY 50 | NTc.Cm13 | HIS 194 | - | HBAcceptor |
| GLY 50 | NTc.Cm13 | HIS 194 | - | VdWContact |
| THR 53 | NTc.Cm10 | SER 191 | - | VdWContact |
| THR 53 | NTc.Cm10 | SER 205 | - | VdWContact |
| THR 53 | NTc.Cm10 | GLN 206 | - | VdWContact |
| THR 53 | NTc.Cm10 | GLU 207 | - | Hydrophobic |
| THR 53 | NTc.Cm10 | GLU 207 | - | VdWContact |
| HIS 54 | NTc.Cm9 | THR 203 | 45.51x51 | HBAcceptor |
| HIS 54 | NTc.Cm9 | THR 203 | 45.51x51 | Hydrophobic |
| HIS 54 | NTc.Cm9 | THR 203 | 45.51x51 | VdWContact |
| HIS 54 | NTc.Cm9 | ARG 286 | 6.62x62 | HBAcceptor |
| HIS 54 | NTc.Cm9 | ARG 286 | 6.62x62 | VdWContact |
| ASN 56 | NTc.Cm7 | THR 212 | - | Hydrophobic |
| ASN 56 | NTc.Cm7 | THR 212 | - | VdWContact |
| GLN 57 | NTc.Cm6 | LYS 288 | 6.64x64 | HBAcceptor |
| GLN 57 | NTc.Cm6 | LYS 288 | 6.64x64 | VdWContact |
| VAL 58 | NTc.Cm5 | TYR 3 | - | Hydrophobic |
| ILE 61 | NTc.Cm2 | LEU 37 | - | Hydrophobic |
| ARG 68 | cxb1.5 | VAL 33 | - | HBDonor |
| ARG 68 | cxb1.5 | VAL 33 | - | VdWContact |
| ARG 68 | cxb1.5 | ASN 35 | - | VdWContact |
| LYS 69 | cxb1.6 | LEU 37 | - | Hydrophobic |
| LYS 69 | cxb1.6 | LEU 37 | - | VdWContact |
| ILE 70 | cxb1.8 | VAL 33 | - | Hydrophobic |
| ILE 70 | cxb1.8 | VAL 33 | - | VdWContact |
| ARG 78 | B1.3 | LEU 21 | - | Hydrophobic |
| ARG 78 | B1.3 | ASP 25 | - | Cationic |
| ARG 78 | B1.3 | ASP 25 | - | HBDonor |
| ARG 78 | B1.3 | ASP 25 | - | VdWContact |
| ARG 78 | B1.3 | TYR 27 | - | CationPi |
| ARG 78 | B1.3 | TYR 27 | - | VdWContact |
| ILE 82 | B1.7 | MET 9 | - | Hydrophobic |
| ILE 82 | B1.7 | LEU 11 | - | Hydrophobic |
| ILE 82 | B1.7 | LEU 17 | - | Hydrophobic |
| ILE 82 | B1.7 | LEU 17 | - | VdWContact |
| ILE 82 | B1.7 | LEU 21 | - | Hydrophobic |
| ILE 82 | B1.7 | LEU 21 | - | VdWContact |
| VAL 83 | b1b2.4 | TYR 3 | - | Hydrophobic |
| VAL 83 | b1b2.4 | MET 9 | - | Hydrophobic |
| GLN 84 | b1b2.6 | MET 1 | - | Hydrophobic |
| GLN 84 | b1b2.6 | MET 1 | - | VdWContact |
| LYS 85 | b1b2.7 | LEU 17 | - | Hydrophobic |
| LYS 85 | b1b2.7 | LEU 17 | - | VdWContact |
| LYS 85 | b1b2.7 | GLU 20 | - | Cationic |
| LYS 85 | b1b2.7 | GLU 20 | - | HBDonor |
| LYS 85 | b1b2.7 | GLU 20 | - | VdWContact |
| LYS 86 | b1b2.8 | MET 9 | - | Hydrophobic |
| LYS 86 | b1b2.8 | MET 9 | - | VdWContact |
| LYS 86 | b1b2.8 | ASP 10 | - | HBDonor |
| LYS 86 | b1b2.8 | ASP 10 | - | VdWContact |
| LYS 86 | b1b2.8 | LEU 14 | - | Hydrophobic |
| LYS 86 | b1b2.8 | LEU 14 | - | VdWContact |
| LEU 87 | b1b2.9 | TYR 3 | - | Hydrophobic |
| LEU 87 | b1b2.9 | TYR 3 | - | VdWContact |
| LEU 87 | b1b2.9 | LEU 7 | - | Hydrophobic |
| LEU 87 | b1b2.9 | LEU 7 | - | VdWContact |
