Predicted complex interactions
CXCL9_HUMAN + CXCR5
SUMMARY
- Chemokine
- CXCL9_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR5 View partner entry
- Partner description
- UniProt: P32302; Gene: cxcr5_human; Family: Chemokine
- Interactions detected
- 91
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| THR 1 | NTc.Cm30 | TYR 275 | 6.51x51 | Hydrophobic |
| THR 1 | NTc.Cm30 | ILE 304 | 7.35x34 | Hydrophobic |
| THR 1 | NTc.Cm30 | ILE 304 | 7.35x34 | VdWContact |
| THR 1 | NTc.Cm30 | THR 305 | 7.36x35 | HBDonor |
| THR 1 | NTc.Cm30 | THR 305 | 7.36x35 | VdWContact |
| THR 1 | NTc.Cm30 | GLU 308 | 7.39x38 | Cationic |
| THR 1 | NTc.Cm30 | GLU 308 | 7.39x38 | Hydrophobic |
| THR 1 | NTc.Cm30 | GLU 308 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm29 | VAL 54 | 1.35x35 | Hydrophobic |
| PRO 2 | NTc.Cm29 | VAL 54 | 1.35x35 | VdWContact |
| PRO 2 | NTc.Cm29 | TYR 58 | 1.39x39 | Hydrophobic |
| PRO 2 | NTc.Cm29 | TYR 58 | 1.39x39 | VdWContact |
| PRO 2 | NTc.Cm29 | ALA 107 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm29 | ALA 107 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm29 | THR 305 | 7.36x35 | VdWContact |
| VAL 3 | NTc.Cm28 | TYR 58 | 1.39x39 | Hydrophobic |
| VAL 3 | NTc.Cm28 | ILE 103 | 2.56x56 | Hydrophobic |
| VAL 3 | NTc.Cm28 | ALA 107 | 2.60x60 | Hydrophobic |
| VAL 3 | NTc.Cm28 | ALA 107 | 2.60x60 | VdWContact |
| VAL 3 | NTc.Cm28 | VAL 125 | 3.28x28 | Hydrophobic |
| VAL 3 | NTc.Cm28 | HIS 129 | 3.32x32 | Hydrophobic |
| VAL 4 | NTc.Cm27 | HIS 129 | 3.32x32 | Hydrophobic |
| LYS 6 | NTc.Cm25 | GLU 184 | 4.60x61 | Cationic |
| LYS 6 | NTc.Cm25 | GLU 184 | 4.60x61 | VdWContact |
| LYS 6 | NTc.Cm25 | THR 203 | 45.51x51 | VdWContact |
| LYS 6 | NTc.Cm25 | PHE 204 | 45.52x52 | Hydrophobic |
| LYS 6 | NTc.Cm25 | PHE 204 | 45.52x52 | VdWContact |
| LYS 6 | NTc.Cm25 | TRP 215 | 5.35x36 | Hydrophobic |
| GLY 7 | NTc.Cm24 | THR 203 | 45.51x51 | VdWContact |
| GLY 7 | NTc.Cm24 | GLN 206 | - | VdWContact |
| GLY 7 | NTc.Cm24 | ARG 286 | 6.62x62 | HBAcceptor |
| GLY 7 | NTc.Cm24 | ARG 286 | 6.62x62 | VdWContact |
| ARG 8 | NTc.Cm23 | ASP 282 | 6.58x58 | Cationic |
| ARG 8 | NTc.Cm23 | ASP 282 | 6.58x58 | VdWContact |
| ARG 8 | NTc.Cm23 | ARG 286 | 6.62x62 | VdWContact |
| ARG 8 | NTc.Cm23 | LEU 300 | 7.31x30 | VdWContact |
| ARG 8 | NTc.Cm23 | ILE 304 | 7.35x34 | VdWContact |
| ILE 12 | NTc.Cm19 | THR 212 | - | Hydrophobic |
| ILE 12 | NTc.Cm19 | THR 212 | - | VdWContact |
| LEU 27 | NTc.Cm4 | HIS 36 | - | HBAcceptor |
| LEU 27 | NTc.Cm4 | HIS 36 | - | Hydrophobic |
| LEU 27 | NTc.Cm4 | HIS 36 | - | VdWContact |
| LYS 28 | NTc.Cm3 | HIS 36 | - | HBAcceptor |
| LYS 28 | NTc.Cm3 | HIS 36 | - | VdWContact |
| LYS 28 | NTc.Cm3 | ASN 292 | - | VdWContact |
| GLN 29 | NTc.Cm2 | HIS 36 | - | HBDonor |
| GLN 29 | NTc.Cm2 | HIS 36 | - | Hydrophobic |
| GLN 29 | NTc.Cm2 | HIS 36 | - | VdWContact |
| GLN 29 | NTc.Cm2 | LEU 37 | - | Hydrophobic |
| GLN 29 | NTc.Cm2 | LEU 37 | - | VdWContact |
| GLN 29 | NTc.Cm2 | CYS 38 | - | HBAcceptor |
| GLN 29 | NTc.Cm2 | CYS 38 | - | VdWContact |
| PHE 30 | NTc.Cm1 | CYS 38 | - | Hydrophobic |
| PHE 30 | NTc.Cm1 | CYS 38 | - | VdWContact |
| PHE 30 | NTc.Cm1 | ASN 292 | - | Hydrophobic |
| PHE 30 | NTc.Cm1 | ASN 292 | - | VdWContact |
| PHE 30 | NTc.Cm1 | ASN 297 | 7.28x27 | Hydrophobic |
| PHE 30 | NTc.Cm1 | ASN 297 | 7.28x27 | VdWContact |
| ALA 31 | CX.1 | ALA 40 | - | Hydrophobic |
| PRO 32 | CX.4 | ALA 40 | - | VdWContact |
| SER 33 | CX.5 | ALA 40 | - | VdWContact |
| PRO 34 | cxb1.1 | ARG 201 | - | VdWContact |
| GLU 37 | cxb1.6 | SER 191 | - | HBAcceptor |
| GLU 37 | cxb1.6 | SER 191 | - | VdWContact |
| GLU 37 | cxb1.6 | GLY 193 | - | VdWContact |
| GLU 37 | cxb1.6 | SER 198 | - | HBAcceptor |
| GLU 37 | cxb1.6 | SER 198 | - | VdWContact |
| ILE 41 | cxb1.11 | HIS 36 | - | Hydrophobic |
| ILE 42 | cxb1.14 | ASN 292 | - | Hydrophobic |
| GLN 50 | B1.6 | LYS 288 | 6.64x64 | HBAcceptor |
| GLN 50 | B1.6 | LYS 288 | 6.64x64 | Hydrophobic |
| GLN 50 | B1.6 | LYS 288 | 6.64x64 | VdWContact |
| GLN 50 | B1.6 | VAL 290 | - | HBDonor |
| GLN 50 | B1.6 | VAL 290 | - | VdWContact |
| GLN 50 | B1.6 | ASP 291 | - | HBDonor |
| GLN 50 | B1.6 | ASP 291 | - | VdWContact |
| GLN 50 | B1.6 | ASN 292 | - | HBAcceptor |
| GLN 50 | B1.6 | ASN 292 | - | VdWContact |
| CYS 52 | b1b2.4 | LYS 288 | 6.64x64 | Anionic |
| CYS 52 | b1b2.4 | LYS 288 | 6.64x64 | HBAcceptor |
| CYS 52 | b1b2.4 | LYS 288 | 6.64x64 | VdWContact |
| ILE 64 | B2.3 | HIS 36 | - | Hydrophobic |
| ILE 64 | B2.3 | HIS 36 | - | VdWContact |
| TRP 67 | B2.6 | HIS 36 | - | Hydrophobic |
| VAL 71 | b2b3.12 | VAL 33 | - | Hydrophobic |
| VAL 71 | b2b3.12 | VAL 33 | - | VdWContact |
| LYS 75 | B3.4 | SER 31 | - | HBDonor |
| LYS 75 | B3.4 | SER 31 | - | VdWContact |
| LYS 75 | B3.4 | VAL 33 | - | Hydrophobic |
| LYS 86 | H.7 | ASP 22 | - | Cationic |
| LYS 86 | H.7 | ASP 22 | - | VdWContact |
