Predicted complex interactions
XCL2_HUMAN + CXCR5
SUMMARY
- Chemokine
- XCL2_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR5 View partner entry
- Partner description
- UniProt: P32302; Gene: cxcr5_human; Family: Chemokine
- Interactions detected
- 72
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm30 | TYR 58 | 1.39x39 | Hydrophobic |
| VAL 1 | NTc.Cm30 | TYR 58 | 1.39x39 | VdWContact |
| VAL 1 | NTc.Cm30 | ILE 103 | 2.56x56 | Hydrophobic |
| VAL 1 | NTc.Cm30 | ALA 107 | 2.60x60 | Hydrophobic |
| VAL 1 | NTc.Cm30 | ALA 107 | 2.60x60 | VdWContact |
| VAL 1 | NTc.Cm30 | GLU 308 | 7.39x38 | Cationic |
| VAL 1 | NTc.Cm30 | GLU 308 | 7.39x38 | HBDonor |
| VAL 1 | NTc.Cm30 | GLU 308 | 7.39x38 | VdWContact |
| VAL 1 | NTc.Cm30 | LEU 312 | 7.43x42 | Hydrophobic |
| GLY 2 | NTc.Cm29 | GLU 308 | 7.39x38 | HBDonor |
| GLY 2 | NTc.Cm29 | GLU 308 | 7.39x38 | VdWContact |
| SER 3 | NTc.Cm28 | ILE 126 | 3.29x29 | VdWContact |
| SER 3 | NTc.Cm28 | PHE 204 | 45.52x52 | VdWContact |
| GLU 4 | NTc.Cm27 | LYS 130 | 3.33x33 | Anionic |
| GLU 4 | NTc.Cm27 | LYS 130 | 3.33x33 | HBAcceptor |
| GLU 4 | NTc.Cm27 | LYS 130 | 3.33x33 | VdWContact |
| GLU 4 | NTc.Cm27 | ARG 219 | 5.39x40 | Anionic |
| GLU 4 | NTc.Cm27 | ARG 219 | 5.39x40 | VdWContact |
| GLU 4 | NTc.Cm27 | TYR 275 | 6.51x51 | Hydrophobic |
| GLU 4 | NTc.Cm27 | TYR 275 | 6.51x51 | VdWContact |
| GLU 4 | NTc.Cm27 | ILE 279 | 6.55x55 | VdWContact |
| GLU 4 | NTc.Cm27 | ARG 286 | 6.62x62 | HBAcceptor |
| GLU 4 | NTc.Cm27 | ARG 286 | 6.62x62 | VdWContact |
| GLU 4 | NTc.Cm27 | ILE 304 | 7.35x34 | Hydrophobic |
| VAL 5 | NTc.Cm26 | PRO 301 | 7.32x31 | Hydrophobic |
| VAL 5 | NTc.Cm26 | PRO 301 | 7.32x31 | VdWContact |
| VAL 5 | NTc.Cm26 | ILE 304 | 7.35x34 | Hydrophobic |
| VAL 5 | NTc.Cm26 | THR 305 | 7.36x35 | VdWContact |
| SER 6 | NTc.Cm25 | ARG 286 | 6.62x62 | VdWContact |
| HIS 7 | NTc.Cm24 | ARG 201 | - | PiCation |
| HIS 7 | NTc.Cm24 | ARG 201 | - | VdWContact |
| ARG 8 | NTc.Cm23 | GLN 206 | - | HBDonor |
| ARG 8 | NTc.Cm23 | GLN 206 | - | VdWContact |
| ARG 8 | NTc.Cm23 | ARG 286 | 6.62x62 | VdWContact |
| ARG 9 | NTc.Cm22 | LEU 37 | - | Hydrophobic |
| ARG 9 | NTc.Cm22 | ALA 40 | - | Hydrophobic |
| ARG 9 | NTc.Cm22 | ALA 40 | - | VdWContact |
| ARG 9 | NTc.Cm22 | HIS 195 | - | CationPi |
| CYS 11 | NTc.Cm20 | HIS 36 | - | VdWContact |
| VAL 12 | NTc.Cm19 | HIS 36 | - | HBDonor |
| VAL 12 | NTc.Cm19 | HIS 36 | - | VdWContact |
| VAL 12 | NTc.Cm19 | CYS 38 | - | VdWContact |
| VAL 12 | NTc.Cm19 | ASN 292 | - | Hydrophobic |
| VAL 12 | NTc.Cm19 | ASN 292 | - | VdWContact |
| VAL 12 | NTc.Cm19 | CYS 294 | 7.25x24 | VdWContact |
| VAL 12 | NTc.Cm19 | ASN 297 | 7.28x27 | VdWContact |
| SER 13 | NTc.Cm18 | HIS 36 | - | HBAcceptor |
| SER 13 | NTc.Cm18 | HIS 36 | - | VdWContact |
| GLN 17 | NTc.Cm14 | LEU 32 | - | Hydrophobic |
| GLN 17 | NTc.Cm14 | LEU 32 | - | VdWContact |
| LEU 19 | NTc.Cm12 | TYR 27 | - | Hydrophobic |
| PRO 20 | NTc.Cm11 | GLU 20 | - | Hydrophobic |
| SER 22 | NTc.Cm9 | GLU 20 | - | HBDonor |
| SER 22 | NTc.Cm9 | GLU 20 | - | VdWContact |
| ARG 23 | NTc.Cm8 | LEU 24 | - | HBDonor |
| ARG 23 | NTc.Cm8 | LEU 24 | - | VdWContact |
| ARG 23 | NTc.Cm8 | TYR 27 | - | VdWContact |
| THR 28 | NTc.Cm3 | HIS 194 | - | Hydrophobic |
| ILE 29 | NTc.Cm2 | HIS 194 | - | Hydrophobic |
| GLU 31 | CX.4 | GLU 207 | - | Hydrophobic |
| ILE 38 | cxb1.8 | LEU 37 | - | Hydrophobic |
| ILE 38 | cxb1.8 | LEU 37 | - | VdWContact |
| ILE 40 | cxb1.11 | HIS 195 | - | Hydrophobic |
| LEU 45 | B1.2 | VAL 33 | - | Hydrophobic |
| LEU 45 | B1.2 | VAL 33 | - | VdWContact |
| LYS 46 | B1.3 | LEU 37 | - | Hydrophobic |
| LYS 46 | B1.3 | LEU 37 | - | VdWContact |
| VAL 47 | B1.4 | HIS 36 | - | Hydrophobic |
| VAL 47 | B1.4 | HIS 36 | - | VdWContact |
| CYS 48 | B1.5 | HIS 36 | - | Hydrophobic |
| CYS 48 | B1.5 | HIS 36 | - | VdWContact |
| CYS 48 | B1.5 | LEU 37 | - | VdWContact |
