Predicted complex interactions
CCL15_HUMAN + CXCR6
SUMMARY
- Chemokine
- CCL15_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR6 View partner entry
- Partner description
- UniProt: O00574; Gene: cxcr6_human; Family: Chemokine
- Interactions detected
- 103
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ASN 19 | NTc.Cm34 | HIS 183 | - | Hydrophobic |
| ASN 19 | NTc.Cm34 | HIS 183 | - | VdWContact |
| PRO 20 | NTc.Cm33 | HIS 183 | - | HBAcceptor |
| PRO 20 | NTc.Cm33 | HIS 183 | - | Hydrophobic |
| PRO 20 | NTc.Cm33 | HIS 183 | - | VdWContact |
| PRO 20 | NTc.Cm33 | ASP 184 | 5.31x32 | HBAcceptor |
| PRO 20 | NTc.Cm33 | ASP 184 | 5.31x32 | Hydrophobic |
| PRO 20 | NTc.Cm33 | ASP 184 | 5.31x32 | VdWContact |
| VAL 21 | NTc.Cm32 | PHE 173 | - | Hydrophobic |
| VAL 21 | NTc.Cm32 | PHE 173 | - | VdWContact |
| VAL 21 | NTc.Cm32 | LEU 175 | - | Hydrophobic |
| VAL 21 | NTc.Cm32 | LEU 175 | - | VdWContact |
| VAL 22 | NTc.Cm31 | GLY 181 | 45.51x51 | VdWContact |
| VAL 22 | NTc.Cm31 | TYR 182 | 45.52x52 | HBAcceptor |
| VAL 22 | NTc.Cm31 | TYR 182 | 45.52x52 | HBDonor |
| VAL 22 | NTc.Cm31 | TYR 182 | 45.52x52 | Hydrophobic |
| VAL 22 | NTc.Cm31 | TYR 182 | 45.52x52 | VdWContact |
| VAL 22 | NTc.Cm31 | ASP 184 | 5.31x32 | Hydrophobic |
| VAL 22 | NTc.Cm31 | ASP 184 | 5.31x32 | VdWContact |
| LEU 23 | NTc.Cm30 | ILE 179 | - | Hydrophobic |
| LEU 23 | NTc.Cm30 | ILE 179 | - | VdWContact |
| ASN 24 | NTc.Cm29 | TRP 87 | 2.60x60 | Hydrophobic |
| ASN 24 | NTc.Cm29 | TRP 87 | 2.60x60 | VdWContact |
| ASN 24 | NTc.Cm29 | LEU 106 | 3.29x29 | Hydrophobic |
| ASN 24 | NTc.Cm29 | LEU 106 | 3.29x29 | VdWContact |
| ASN 24 | NTc.Cm29 | CYS 180 | 45.50x50 | HBDonor |
| ASN 24 | NTc.Cm29 | CYS 180 | 45.50x50 | VdWContact |
| ASN 24 | NTc.Cm29 | GLY 181 | 45.51x51 | VdWContact |
| ASN 24 | NTc.Cm29 | TYR 182 | 45.52x52 | VdWContact |
| SER 25 | NTc.Cm28 | TYR 38 | 1.39x39 | HBAcceptor |
| SER 25 | NTc.Cm28 | TYR 38 | 1.39x39 | VdWContact |
| SER 25 | NTc.Cm28 | TRP 87 | 2.60x60 | VdWContact |
| SER 25 | NTc.Cm28 | GLU 274 | 7.39x38 | VdWContact |
| PHE 26 | NTc.Cm27 | LEU 106 | 3.29x29 | Hydrophobic |
| PHE 26 | NTc.Cm27 | LEU 106 | 3.29x29 | VdWContact |
| PHE 26 | NTc.Cm27 | TYR 109 | 3.32x32 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TYR 109 | 3.32x32 | PiStacking |
| PHE 26 | NTc.Cm27 | TYR 109 | 3.32x32 | VdWContact |
| PHE 26 | NTc.Cm27 | TYR 182 | 45.52x52 | VdWContact |
| PHE 26 | NTc.Cm27 | PHE 247 | 6.51x51 | Hydrophobic |
| PHE 26 | NTc.Cm27 | PHE 247 | 6.51x51 | VdWContact |
| PHE 26 | NTc.Cm27 | LYS 251 | 6.55x55 | Hydrophobic |
| PHE 26 | NTc.Cm27 | GLU 274 | 7.39x38 | HBDonor |
| PHE 26 | NTc.Cm27 | GLU 274 | 7.39x38 | VdWContact |
| PHE 26 | NTc.Cm27 | TYR 278 | 7.43x42 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TYR 278 | 7.43x42 | VdWContact |
| HIS 27 | NTc.Cm26 | LEU 34 | 1.35x35 | Hydrophobic |
| HIS 27 | NTc.Cm26 | LEU 34 | 1.35x35 | VdWContact |
| HIS 27 | NTc.Cm26 | GLU 274 | 7.39x38 | VdWContact |
| PHE 28 | NTc.Cm25 | TYR 182 | 45.52x52 | Hydrophobic |
| PHE 28 | NTc.Cm25 | TYR 182 | 45.52x52 | VdWContact |
| PHE 28 | NTc.Cm25 | ARG 254 | 6.58x58 | HBAcceptor |
| PHE 28 | NTc.Cm25 | ARG 254 | 6.58x58 | VdWContact |
| PHE 28 | NTc.Cm25 | TYR 261 | 7.26x25 | VdWContact |
| ALA 29 | NTc.Cm24 | LEU 175 | - | Hydrophobic |
| ALA 29 | NTc.Cm24 | ARG 254 | 6.58x58 | HBAcceptor |
| ALA 29 | NTc.Cm24 | ARG 254 | 6.58x58 | VdWContact |
| ALA 29 | NTc.Cm24 | TYR 261 | 7.26x25 | VdWContact |
| ALA 30 | NTc.Cm23 | LEU 175 | - | VdWContact |
| ALA 30 | NTc.Cm23 | TYR 261 | 7.26x25 | VdWContact |
| CYS 32 | NTc.Cm21 | LEU 175 | - | Hydrophobic |
| CYS 32 | NTc.Cm21 | LEU 175 | - | VdWContact |
| THR 34 | NTc.Cm19 | LEU 175 | - | Hydrophobic |
| THR 34 | NTc.Cm19 | LEU 175 | - | VdWContact |
| THR 34 | NTc.Cm19 | ASP 176 | - | Hydrophobic |
| THR 34 | NTc.Cm19 | ASP 176 | - | VdWContact |
| PHE 50 | NTc.Cm3 | TRP 258 | - | Hydrophobic |
| PHE 50 | NTc.Cm3 | TRP 258 | - | VdWContact |
| GLU 51 | NTc.Cm2 | ALA 262 | 7.27x26 | Hydrophobic |
| GLU 51 | NTc.Cm2 | ALA 262 | 7.27x26 | VdWContact |
| SER 53 | CX.1 | TYR 261 | 7.26x25 | VdWContact |
| SER 53 | CX.1 | HIS 267 | 7.32x31 | VdWContact |
| SER 54 | CX.5 | HIS 23 | - | VdWContact |
| SER 54 | CX.5 | PHE 26 | 1.27x27 | VdWContact |
| SER 54 | CX.5 | LEU 27 | 1.28x28 | VdWContact |
| SER 54 | CX.5 | HIS 267 | 7.32x31 | VdWContact |
| GLU 55 | cxb1.1 | PHE 26 | 1.27x27 | Hydrophobic |
| GLU 55 | cxb1.1 | LEU 27 | 1.28x28 | VdWContact |
| CYS 56 | cxb1.2 | HIS 23 | - | HBAcceptor |
| CYS 56 | cxb1.2 | HIS 23 | - | VdWContact |
| CYS 56 | cxb1.2 | LEU 27 | 1.28x28 | VdWContact |
| SER 57 | cxb1.5 | ASP 176 | - | HBDonor |
| SER 57 | cxb1.5 | ASP 176 | - | VdWContact |
| LYS 58 | cxb1.6 | ASP 176 | - | Cationic |
| PRO 59 | cxb1.7 | GLN 20 | - | Hydrophobic |
| PRO 59 | cxb1.7 | HIS 23 | - | Hydrophobic |
| PRO 59 | cxb1.7 | HIS 23 | - | VdWContact |
| PRO 75 | b1b2.9 | GLN 20 | - | VdWContact |
| SER 76 | b1b2.10 | GLN 20 | - | HBAcceptor |
| SER 76 | b1b2.10 | GLN 20 | - | VdWContact |
| GLN 81 | B2.1 | ASN 16 | - | VdWContact |
| LYS 85 | B2.5 | PHE 12 | - | CationPi |
| LYS 85 | B2.5 | PHE 12 | - | Hydrophobic |
| LYS 85 | B2.5 | PHE 12 | - | VdWContact |
| PRO 89 | b2b3.11 | TRP 258 | - | Hydrophobic |
| PRO 89 | b2b3.11 | TRP 258 | - | VdWContact |
| PRO 89 | b2b3.11 | GLU 259 | 7.24x23 | Hydrophobic |
| TYR 90 | b2b3.12 | TRP 258 | - | VdWContact |
| SER 91 | B3.1 | TRP 258 | - | VdWContact |
| ILE 92 | B3.2 | ASP 184 | 5.31x32 | Hydrophobic |
| ILE 92 | B3.2 | GLU 185 | 5.32x33 | Hydrophobic |
| ILE 92 | B3.2 | TRP 258 | - | Hydrophobic |
| ILE 92 | B3.2 | TRP 258 | - | VdWContact |
