Predicted complex interactions
CCL18_HUMAN + CXCR6
SUMMARY
- Chemokine
- CCL18_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR6 View partner entry
- Partner description
- UniProt: O00574; Gene: cxcr6_human; Family: Chemokine
- Interactions detected
- 131
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm29 | ASP 9 | - | Cationic |
| ALA 1 | NTc.Cm29 | ASP 9 | - | Hydrophobic |
| ALA 1 | NTc.Cm29 | ASP 9 | - | VdWContact |
| ALA 1 | NTc.Cm29 | TYR 10 | - | VdWContact |
| ALA 1 | NTc.Cm29 | GLY 11 | - | HBAcceptor |
| ALA 1 | NTc.Cm29 | GLY 11 | - | VdWContact |
| GLN 2 | NTc.Cm28 | ASP 9 | - | HBDonor |
| GLN 2 | NTc.Cm28 | ASP 9 | - | VdWContact |
| GLN 2 | NTc.Cm28 | TYR 10 | - | Hydrophobic |
| GLN 2 | NTc.Cm28 | TYR 10 | - | VdWContact |
| GLN 2 | NTc.Cm28 | SER 13 | - | VdWContact |
| VAL 3 | NTc.Cm27 | GLY 11 | - | VdWContact |
| VAL 3 | NTc.Cm27 | PHE 12 | - | Hydrophobic |
| VAL 3 | NTc.Cm27 | PHE 12 | - | VdWContact |
| VAL 3 | NTc.Cm27 | SER 13 | - | HBAcceptor |
| VAL 3 | NTc.Cm27 | SER 13 | - | VdWContact |
| VAL 3 | NTc.Cm27 | SER 14 | - | VdWContact |
| GLY 4 | NTc.Cm26 | GLY 11 | - | VdWContact |
| GLY 4 | NTc.Cm26 | PHE 12 | - | HBDonor |
| GLY 4 | NTc.Cm26 | PHE 12 | - | VdWContact |
| GLY 4 | NTc.Cm26 | SER 14 | - | VdWContact |
| THR 5 | NTc.Cm25 | SER 14 | - | VdWContact |
| THR 5 | NTc.Cm25 | PHE 15 | - | VdWContact |
| ASN 6 | NTc.Cm24 | SER 13 | - | VdWContact |
| ASN 6 | NTc.Cm24 | SER 14 | - | VdWContact |
| ASN 6 | NTc.Cm24 | PHE 15 | - | HBAcceptor |
| ASN 6 | NTc.Cm24 | PHE 15 | - | VdWContact |
| ASN 6 | NTc.Cm24 | ASN 16 | - | HBAcceptor |
| ASN 6 | NTc.Cm24 | ASN 16 | - | VdWContact |
| ASN 6 | NTc.Cm24 | ASP 17 | - | HBAcceptor |
| ASN 6 | NTc.Cm24 | ASP 17 | - | HBDonor |
| ASN 6 | NTc.Cm24 | ASP 17 | - | Hydrophobic |
| ASN 6 | NTc.Cm24 | ASP 17 | - | VdWContact |
| ASN 6 | NTc.Cm24 | SER 18 | - | HBAcceptor |
| ASN 6 | NTc.Cm24 | SER 18 | - | VdWContact |
| LYS 7 | NTc.Cm23 | PHE 15 | - | HBDonor |
| LYS 7 | NTc.Cm23 | PHE 15 | - | VdWContact |
| LYS 7 | NTc.Cm23 | ASN 16 | - | HBDonor |
| LYS 7 | NTc.Cm23 | ASN 16 | - | VdWContact |
| LYS 7 | NTc.Cm23 | ASP 17 | - | HBAcceptor |
| LYS 7 | NTc.Cm23 | ASP 17 | - | VdWContact |
| LYS 7 | NTc.Cm23 | SER 18 | - | VdWContact |
| LYS 7 | NTc.Cm23 | SER 19 | - | VdWContact |
| LYS 7 | NTc.Cm23 | GLU 22 | - | Cationic |
| LYS 7 | NTc.Cm23 | GLU 22 | - | HBDonor |
| LYS 7 | NTc.Cm23 | GLU 22 | - | VdWContact |
| GLU 8 | NTc.Cm22 | ASN 16 | - | VdWContact |
| GLU 8 | NTc.Cm22 | ASP 17 | - | HBDonor |
| GLU 8 | NTc.Cm22 | ASP 17 | - | Hydrophobic |
| GLU 8 | NTc.Cm22 | ASP 17 | - | VdWContact |
| GLU 8 | NTc.Cm22 | GLN 20 | - | HBAcceptor |
| GLU 8 | NTc.Cm22 | GLN 20 | - | Hydrophobic |
| GLU 8 | NTc.Cm22 | GLN 20 | - | VdWContact |
| LEU 9 | NTc.Cm21 | HIS 23 | - | Hydrophobic |
| CYS 10 | NTc.Cm20 | GLN 20 | - | Hydrophobic |
| CYS 10 | NTc.Cm20 | GLN 20 | - | VdWContact |
| CYS 10 | NTc.Cm20 | GLN 24 | 1.25x25 | Hydrophobic |
| CYS 10 | NTc.Cm20 | GLN 24 | 1.25x25 | VdWContact |
| LEU 12 | NTc.Cm18 | GLN 24 | 1.25x25 | Hydrophobic |
| LEU 12 | NTc.Cm18 | GLN 24 | 1.25x25 | VdWContact |
| LEU 12 | NTc.Cm18 | LEU 27 | 1.28x28 | Hydrophobic |
| VAL 13 | NTc.Cm17 | LEU 175 | - | Hydrophobic |
| VAL 13 | NTc.Cm17 | ASP 176 | - | VdWContact |
| VAL 13 | NTc.Cm17 | ILE 179 | - | Hydrophobic |
| VAL 13 | NTc.Cm17 | ILE 179 | - | VdWContact |
| TYR 14 | NTc.Cm16 | LEU 175 | - | Hydrophobic |
| TYR 14 | NTc.Cm16 | LEU 175 | - | VdWContact |
| TYR 14 | NTc.Cm16 | ASP 176 | - | HBDonor |
| TYR 14 | NTc.Cm16 | ASP 176 | - | Hydrophobic |
| TYR 14 | NTc.Cm16 | ASP 176 | - | VdWContact |
| THR 15 | NTc.Cm15 | LEU 175 | - | VdWContact |
| SER 16 | NTc.Cm14 | PHE 173 | - | VdWContact |
| SER 16 | NTc.Cm14 | LEU 175 | - | VdWContact |
| SER 16 | NTc.Cm14 | ILE 179 | - | VdWContact |
| TRP 17 | NTc.Cm13 | PHE 173 | - | Hydrophobic |
| TRP 17 | NTc.Cm13 | PHE 173 | - | VdWContact |
| TRP 17 | NTc.Cm13 | ILE 179 | - | Hydrophobic |
| TRP 17 | NTc.Cm13 | GLY 181 | 45.51x51 | VdWContact |
| TRP 17 | NTc.Cm13 | TYR 182 | 45.52x52 | VdWContact |
| TRP 17 | NTc.Cm13 | HIS 183 | - | Hydrophobic |
| TRP 17 | NTc.Cm13 | HIS 183 | - | VdWContact |
| TRP 17 | NTc.Cm13 | ASP 184 | 5.31x32 | VdWContact |
| GLN 18 | NTc.Cm12 | HIS 183 | - | Hydrophobic |
| GLN 18 | NTc.Cm12 | HIS 183 | - | VdWContact |
| ILE 19 | NTc.Cm11 | ASP 184 | 5.31x32 | Hydrophobic |
| LYS 22 | NTc.Cm8 | GLU 185 | 5.32x33 | Cationic |
| LYS 22 | NTc.Cm8 | GLU 185 | 5.32x33 | VdWContact |
| PHE 23 | NTc.Cm7 | GLU 185 | 5.32x33 | Hydrophobic |
| PHE 23 | NTc.Cm7 | GLU 185 | 5.32x33 | VdWContact |
| PHE 23 | NTc.Cm7 | TRP 258 | - | Hydrophobic |
| CYS 34 | cxb1.5 | GLN 20 | - | VdWContact |
| LYS 36 | cxb1.7 | ASP 176 | - | Cationic |
| LYS 36 | cxb1.7 | ASP 176 | - | HBDonor |
| LYS 36 | cxb1.7 | ASP 176 | - | VdWContact |
| LEU 42 | cxb1.16 | TRP 258 | - | Hydrophobic |
| LEU 42 | cxb1.16 | TRP 258 | - | VdWContact |
| THR 43 | B1.1 | TRP 258 | - | Hydrophobic |
| THR 43 | B1.1 | TRP 258 | - | VdWContact |
| LYS 44 | B1.2 | TRP 258 | - | Hydrophobic |
| LYS 44 | B1.2 | TRP 258 | - | VdWContact |
| ARG 45 | B1.3 | GLU 185 | 5.32x33 | Cationic |
| ARG 45 | B1.3 | SER 255 | 6.59x59 | HBDonor |
| ARG 45 | B1.3 | SER 255 | 6.59x59 | VdWContact |
| ARG 45 | B1.3 | THR 256 | 6.60x60 | VdWContact |
| ARG 45 | B1.3 | TRP 258 | - | Hydrophobic |
| ARG 45 | B1.3 | TRP 258 | - | VdWContact |
| ARG 45 | B1.3 | GLU 259 | 7.24x23 | Hydrophobic |
| ARG 45 | B1.3 | GLU 259 | 7.24x23 | VdWContact |
| GLY 46 | B1.4 | TRP 258 | - | HBDonor |
| GLY 46 | B1.4 | TRP 258 | - | VdWContact |
| GLY 46 | B1.4 | GLU 259 | 7.24x23 | VdWContact |
| GLY 46 | B1.4 | ALA 262 | 7.27x26 | VdWContact |
| ARG 47 | B1.5 | ARG 254 | 6.58x58 | HBDonor |
| ARG 47 | B1.5 | ARG 254 | 6.58x58 | VdWContact |
| ARG 47 | B1.5 | TRP 258 | - | HBDonor |
| ARG 47 | B1.5 | TRP 258 | - | Hydrophobic |
| ARG 47 | B1.5 | TRP 258 | - | VdWContact |
| ARG 47 | B1.5 | GLU 259 | 7.24x23 | VdWContact |
| ARG 47 | B1.5 | TYR 260 | 7.25x24 | HBDonor |
| ARG 47 | B1.5 | TYR 260 | 7.25x24 | VdWContact |
| ARG 47 | B1.5 | TYR 261 | 7.26x25 | CationPi |
| ARG 47 | B1.5 | TYR 261 | 7.26x25 | Hydrophobic |
| ARG 47 | B1.5 | TYR 261 | 7.26x25 | VdWContact |
| ARG 47 | B1.5 | ALA 262 | 7.27x26 | Hydrophobic |
| ARG 47 | B1.5 | ALA 262 | 7.27x26 | VdWContact |
| GLN 48 | B1.6 | ALA 262 | 7.27x26 | Hydrophobic |
| GLN 48 | B1.6 | ALA 262 | 7.27x26 | VdWContact |
| ILE 49 | B1.7 | TYR 261 | 7.26x25 | Hydrophobic |
| ILE 49 | B1.7 | TYR 261 | 7.26x25 | VdWContact |
| LYS 55 | b1b2.13 | ASN 174 | - | HBDonor |
| LYS 55 | b1b2.13 | ASN 174 | - | VdWContact |
