Predicted complex interactions
CCL2_HUMAN + CXCR6
SUMMARY
- Chemokine
- CCL2_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR6 View partner entry
- Partner description
- UniProt: O00574; Gene: cxcr6_human; Family: Chemokine
- Interactions detected
- 93
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm33 | LEU 106 | 3.29x29 | Hydrophobic |
| GLN 1 | NTc.Cm33 | LEU 106 | 3.29x29 | VdWContact |
| GLN 1 | NTc.Cm33 | TYR 109 | 3.32x32 | VdWContact |
| GLN 1 | NTc.Cm33 | TYR 182 | 45.52x52 | Hydrophobic |
| GLN 1 | NTc.Cm33 | TYR 182 | 45.52x52 | VdWContact |
| GLN 1 | NTc.Cm33 | PHE 247 | 6.51x51 | VdWContact |
| GLN 1 | NTc.Cm33 | TYR 278 | 7.43x42 | HBDonor |
| GLN 1 | NTc.Cm33 | TYR 278 | 7.43x42 | VdWContact |
| PRO 2 | NTc.Cm32 | TYR 38 | 1.39x39 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TRP 87 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TRP 87 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm32 | GLU 274 | 7.39x38 | VdWContact |
| ASP 3 | NTc.Cm31 | LYS 251 | 6.55x55 | Anionic |
| ASP 3 | NTc.Cm31 | LYS 251 | 6.55x55 | VdWContact |
| ASP 3 | NTc.Cm31 | ARG 254 | 6.58x58 | Anionic |
| ASP 3 | NTc.Cm31 | ARG 254 | 6.58x58 | HBAcceptor |
| ASP 3 | NTc.Cm31 | ARG 254 | 6.58x58 | VdWContact |
| ASP 3 | NTc.Cm31 | ILE 270 | 7.35x34 | Hydrophobic |
| ASP 3 | NTc.Cm31 | GLU 274 | 7.39x38 | HBDonor |
| ASP 3 | NTc.Cm31 | GLU 274 | 7.39x38 | VdWContact |
| ALA 4 | NTc.Cm30 | LEU 34 | 1.35x35 | Hydrophobic |
| ALA 4 | NTc.Cm30 | ILE 270 | 7.35x34 | Hydrophobic |
| ALA 4 | NTc.Cm30 | MET 271 | 7.36x35 | Hydrophobic |
| ALA 4 | NTc.Cm30 | MET 271 | 7.36x35 | VdWContact |
| ALA 4 | NTc.Cm30 | GLU 274 | 7.39x38 | HBDonor |
| ALA 4 | NTc.Cm30 | GLU 274 | 7.39x38 | VdWContact |
| ILE 5 | NTc.Cm29 | LEU 34 | 1.35x35 | Hydrophobic |
| ILE 5 | NTc.Cm29 | TYR 38 | 1.39x39 | Hydrophobic |
| ILE 5 | NTc.Cm29 | TYR 38 | 1.39x39 | VdWContact |
| ILE 5 | NTc.Cm29 | TRP 87 | 2.60x60 | Hydrophobic |
| ILE 5 | NTc.Cm29 | TRP 87 | 2.60x60 | VdWContact |
| ILE 5 | NTc.Cm29 | GLY 91 | 2.64x64 | VdWContact |
| ASN 6 | NTc.Cm28 | ILE 179 | - | VdWContact |
| ASN 6 | NTc.Cm28 | CYS 180 | 45.50x50 | HBDonor |
| ASN 6 | NTc.Cm28 | CYS 180 | 45.50x50 | VdWContact |
| ALA 7 | NTc.Cm27 | PHE 26 | 1.27x27 | Hydrophobic |
| ALA 7 | NTc.Cm27 | HIS 267 | 7.32x31 | Hydrophobic |
| PRO 8 | NTc.Cm26 | TYR 261 | 7.26x25 | VdWContact |
| PRO 8 | NTc.Cm26 | HIS 267 | 7.32x31 | Hydrophobic |
| PRO 8 | NTc.Cm26 | HIS 267 | 7.32x31 | VdWContact |
| VAL 9 | NTc.Cm25 | LEU 175 | - | Hydrophobic |
| VAL 9 | NTc.Cm25 | ASP 176 | - | Hydrophobic |
| VAL 9 | NTc.Cm25 | ASP 176 | - | VdWContact |
| THR 10 | NTc.Cm24 | GLN 20 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | HIS 23 | - | HBDonor |
| THR 10 | NTc.Cm24 | HIS 23 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | HIS 23 | - | VdWContact |
| CYS 11 | NTc.Cm23 | ALA 262 | 7.27x26 | Hydrophobic |
| CYS 11 | NTc.Cm23 | ALA 262 | 7.27x26 | VdWContact |
| TYR 13 | NTc.Cm21 | TRP 258 | - | Hydrophobic |
| TYR 13 | NTc.Cm21 | TRP 258 | - | VdWContact |
| TYR 13 | NTc.Cm21 | GLU 259 | 7.24x23 | Hydrophobic |
| TYR 13 | NTc.Cm21 | GLU 259 | 7.24x23 | VdWContact |
| TYR 13 | NTc.Cm21 | ALA 262 | 7.27x26 | HBAcceptor |
| TYR 13 | NTc.Cm21 | ALA 262 | 7.27x26 | Hydrophobic |
| TYR 13 | NTc.Cm21 | ALA 262 | 7.27x26 | VdWContact |
| TYR 13 | NTc.Cm21 | MET 263 | 7.28x27 | HBDonor |
| TYR 13 | NTc.Cm21 | MET 263 | 7.28x27 | Hydrophobic |
| TYR 13 | NTc.Cm21 | MET 263 | 7.28x27 | VdWContact |
| ARG 18 | NTc.Cm16 | TYR 10 | - | HBDonor |
| ARG 18 | NTc.Cm16 | TYR 10 | - | VdWContact |
| ARG 18 | NTc.Cm16 | GLY 11 | - | HBDonor |
| ARG 18 | NTc.Cm16 | GLY 11 | - | VdWContact |
| ARG 18 | NTc.Cm16 | PHE 12 | - | CationPi |
| ARG 18 | NTc.Cm16 | PHE 12 | - | Hydrophobic |
| ARG 18 | NTc.Cm16 | PHE 12 | - | VdWContact |
| LYS 19 | NTc.Cm15 | PHE 12 | - | VdWContact |
| ILE 20 | NTc.Cm14 | PHE 12 | - | Hydrophobic |
| ARG 29 | NTc.Cm5 | ASP 176 | - | Cationic |
| ARG 29 | NTc.Cm5 | ASP 176 | - | VdWContact |
| SER 34 | CX.1 | HIS 183 | - | VdWContact |
| SER 34 | CX.1 | ASP 184 | 5.31x32 | VdWContact |
| LYS 35 | CX.5 | PHE 173 | - | Hydrophobic |
| LYS 35 | CX.5 | PHE 173 | - | VdWContact |
| LYS 35 | CX.5 | LEU 175 | - | Hydrophobic |
| LYS 35 | CX.5 | LEU 175 | - | VdWContact |
| LYS 35 | CX.5 | ILE 179 | - | VdWContact |
| LYS 35 | CX.5 | TYR 182 | 45.52x52 | VdWContact |
| LYS 35 | CX.5 | ASP 184 | 5.31x32 | VdWContact |
| LYS 35 | CX.5 | TYR 261 | 7.26x25 | VdWContact |
| PRO 37 | cxb1.2 | TRP 258 | - | Hydrophobic |
| PRO 37 | cxb1.2 | TRP 258 | - | VdWContact |
| LYS 38 | cxb1.5 | TRP 258 | - | Hydrophobic |
| LYS 38 | cxb1.5 | TRP 258 | - | VdWContact |
| ALA 48 | B1.2 | GLN 20 | - | HBAcceptor |
| ALA 48 | B1.2 | GLN 20 | - | VdWContact |
| LYS 49 | B1.3 | ASP 17 | - | Cationic |
| LYS 49 | B1.3 | ASP 17 | - | HBDonor |
| LYS 49 | B1.3 | ASP 17 | - | VdWContact |
| LYS 49 | B1.3 | GLN 20 | - | VdWContact |
| GLU 50 | B1.4 | GLN 20 | - | HBDonor |
| GLU 50 | B1.4 | GLN 20 | - | Hydrophobic |
| GLU 50 | B1.4 | GLN 20 | - | VdWContact |
