Predicted complex interactions
CCL20_HUMAN + CXCR6
SUMMARY
- Chemokine
- CCL20_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR6 View partner entry
- Partner description
- UniProt: O00574; Gene: cxcr6_human; Family: Chemokine
- Interactions detected
- 101
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm31 | SER 14 | - | HBDonor |
| ALA 1 | NTc.Cm31 | SER 14 | - | VdWContact |
| ALA 1 | NTc.Cm31 | PHE 15 | - | Hydrophobic |
| ALA 1 | NTc.Cm31 | PHE 15 | - | VdWContact |
| ALA 1 | NTc.Cm31 | ASN 16 | - | HBAcceptor |
| ALA 1 | NTc.Cm31 | ASN 16 | - | HBDonor |
| ALA 1 | NTc.Cm31 | ASN 16 | - | VdWContact |
| SER 2 | NTc.Cm30 | PHE 15 | - | VdWContact |
| ASN 3 | NTc.Cm29 | SER 18 | - | HBAcceptor |
| ASN 3 | NTc.Cm29 | SER 18 | - | HBDonor |
| ASN 3 | NTc.Cm29 | SER 18 | - | VdWContact |
| ASN 3 | NTc.Cm29 | SER 19 | - | VdWContact |
| ASN 3 | NTc.Cm29 | GLU 22 | - | HBDonor |
| ASN 3 | NTc.Cm29 | GLU 22 | - | VdWContact |
| PHE 4 | NTc.Cm28 | SER 19 | - | VdWContact |
| PHE 4 | NTc.Cm28 | ALA 262 | 7.27x26 | Hydrophobic |
| PHE 4 | NTc.Cm28 | ALA 262 | 7.27x26 | VdWContact |
| ASP 5 | NTc.Cm27 | HIS 23 | - | HBAcceptor |
| ASP 5 | NTc.Cm27 | HIS 23 | - | Hydrophobic |
| ASP 5 | NTc.Cm27 | HIS 23 | - | VdWContact |
| ASP 5 | NTc.Cm27 | THR 264 | 7.29x28 | HBAcceptor |
| ASP 5 | NTc.Cm27 | THR 264 | 7.29x28 | Hydrophobic |
| ASP 5 | NTc.Cm27 | THR 264 | 7.29x28 | VdWContact |
| ASP 5 | NTc.Cm27 | HIS 267 | 7.32x31 | Hydrophobic |
| CYS 6 | NTc.Cm26 | HIS 23 | - | Hydrophobic |
| CYS 6 | NTc.Cm26 | HIS 23 | - | VdWContact |
| CYS 6 | NTc.Cm26 | LEU 27 | 1.28x28 | Hydrophobic |
| LEU 8 | NTc.Cm24 | PHE 26 | 1.27x27 | Hydrophobic |
| LEU 8 | NTc.Cm24 | PHE 26 | 1.27x27 | VdWContact |
| LEU 8 | NTc.Cm24 | LEU 27 | 1.28x28 | Hydrophobic |
| LEU 8 | NTc.Cm24 | LEU 27 | 1.28x28 | VdWContact |
| LEU 8 | NTc.Cm24 | HIS 267 | 7.32x31 | Hydrophobic |
| TYR 10 | NTc.Cm22 | LEU 175 | - | Hydrophobic |
| TYR 10 | NTc.Cm22 | LEU 175 | - | VdWContact |
| TYR 10 | NTc.Cm22 | ASP 184 | 5.31x32 | VdWContact |
| TYR 10 | NTc.Cm22 | TYR 261 | 7.26x25 | VdWContact |
| THR 11 | NTc.Cm21 | TRP 258 | - | VdWContact |
| ASP 12 | NTc.Cm20 | ASP 184 | 5.31x32 | VdWContact |
| ASP 12 | NTc.Cm20 | GLU 185 | 5.32x33 | HBAcceptor |
| ASP 12 | NTc.Cm20 | GLU 185 | 5.32x33 | Hydrophobic |
| ASP 12 | NTc.Cm20 | GLU 185 | 5.32x33 | VdWContact |
| ASP 12 | NTc.Cm20 | TYR 261 | 7.26x25 | VdWContact |
| ARG 13 | NTc.Cm19 | GLU 185 | 5.32x33 | Cationic |
| ARG 13 | NTc.Cm19 | GLU 185 | 5.32x33 | HBDonor |
| ARG 13 | NTc.Cm19 | GLU 185 | 5.32x33 | VdWContact |
| ARG 13 | NTc.Cm19 | SER 255 | 6.59x59 | VdWContact |
| ARG 13 | NTc.Cm19 | THR 256 | 6.60x60 | HBDonor |
| ARG 13 | NTc.Cm19 | THR 256 | 6.60x60 | VdWContact |
| ARG 13 | NTc.Cm19 | TRP 258 | - | Hydrophobic |
| ARG 13 | NTc.Cm19 | TRP 258 | - | VdWContact |
| LEU 15 | NTc.Cm17 | TRP 258 | - | Hydrophobic |
| LEU 15 | NTc.Cm17 | TRP 258 | - | VdWContact |
| THR 24 | NTc.Cm8 | GLN 20 | - | VdWContact |
| ALA 28 | NTc.Cm4 | ASP 176 | - | HBDonor |
| ALA 28 | NTc.Cm4 | ASP 176 | - | Hydrophobic |
| ALA 28 | NTc.Cm4 | ASP 176 | - | VdWContact |
| GLU 30 | NTc.Cm2 | GLN 24 | 1.25x25 | VdWContact |
| GLY 31 | NTc.Cm1 | GLN 24 | 1.25x25 | VdWContact |
| CYS 32 | CX.1 | LEU 27 | 1.28x28 | Hydrophobic |
| CYS 32 | CX.1 | LEU 27 | 1.28x28 | VdWContact |
| ASP 33 | CX.5 | LEU 27 | 1.28x28 | VdWContact |
| ASP 33 | CX.5 | LYS 31 | 1.32x32 | Anionic |
| ASP 33 | CX.5 | LYS 177 | - | Anionic |
| ASP 33 | CX.5 | LYS 177 | - | HBAcceptor |
| ASP 33 | CX.5 | LYS 177 | - | VdWContact |
| ILE 34 | cxb1.1 | LEU 175 | - | Hydrophobic |
| ILE 34 | cxb1.1 | ILE 179 | - | Hydrophobic |
| ILE 34 | cxb1.1 | ILE 179 | - | VdWContact |
| ASN 35 | cxb1.2 | ASP 176 | - | HBDonor |
| ASN 35 | cxb1.2 | ASP 176 | - | VdWContact |
| HIS 40 | cxb1.10 | PHE 15 | - | Hydrophobic |
| HIS 40 | cxb1.10 | PHE 15 | - | PiStacking |
| HIS 40 | cxb1.10 | PHE 15 | - | VdWContact |
| THR 41 | cxb1.11 | TRP 258 | - | Hydrophobic |
| THR 41 | cxb1.11 | TRP 258 | - | VdWContact |
| LYS 43 | cxb1.15 | GLU 259 | 7.24x23 | Cationic |
| LYS 43 | cxb1.15 | GLU 259 | 7.24x23 | HBDonor |
| LYS 43 | cxb1.15 | GLU 259 | 7.24x23 | VdWContact |
| LEU 45 | B1.1 | GLU 259 | 7.24x23 | Hydrophobic |
| LEU 45 | B1.1 | GLU 259 | 7.24x23 | VdWContact |
| LEU 45 | B1.1 | MET 263 | 7.28x27 | Hydrophobic |
| SER 46 | B1.2 | ALA 262 | 7.27x26 | VdWContact |
| VAL 47 | B1.3 | TRP 258 | - | Hydrophobic |
| VAL 47 | B1.3 | TRP 258 | - | VdWContact |
| VAL 47 | B1.3 | ALA 262 | 7.27x26 | Hydrophobic |
| VAL 47 | B1.3 | ALA 262 | 7.27x26 | VdWContact |
| CYS 48 | B1.4 | TYR 261 | 7.26x25 | VdWContact |
| ASN 50 | B1.6 | LEU 175 | - | VdWContact |
| LYS 52 | b1b2.4 | ASN 174 | - | HBDonor |
| LYS 52 | b1b2.4 | ASN 174 | - | VdWContact |
| LYS 52 | b1b2.4 | LEU 175 | - | VdWContact |
| GLN 53 | b1b2.6 | HIS 183 | - | Hydrophobic |
| GLN 53 | b1b2.6 | HIS 183 | - | VdWContact |
| GLN 53 | b1b2.6 | ASP 184 | 5.31x32 | HBDonor |
| GLN 53 | b1b2.6 | ASP 184 | 5.31x32 | VdWContact |
| VAL 67 | B2.6 | TYR 10 | - | Hydrophobic |
| VAL 67 | B2.6 | TYR 10 | - | VdWContact |
| LYS 68 | b2b3.2 | TYR 10 | - | VdWContact |
| MET 70 | b2b3.11 | TYR 10 | - | HBAcceptor |
| MET 70 | b2b3.11 | TYR 10 | - | Hydrophobic |
| MET 70 | b2b3.11 | TYR 10 | - | VdWContact |
