Predicted complex interactions
CCL22_HUMAN + CXCR6
SUMMARY
- Chemokine
- CCL22_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR6 View partner entry
- Partner description
- UniProt: O00574; Gene: cxcr6_human; Family: Chemokine
- Interactions detected
- 90
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm35 | TYR 38 | 1.39x39 | HBDonor |
| GLY 1 | NTc.Cm35 | TYR 38 | 1.39x39 | VdWContact |
| GLY 1 | NTc.Cm35 | TRP 87 | 2.60x60 | VdWContact |
| GLY 1 | NTc.Cm35 | GLU 274 | 7.39x38 | Cationic |
| GLY 1 | NTc.Cm35 | GLU 274 | 7.39x38 | VdWContact |
| GLY 1 | NTc.Cm35 | TYR 278 | 7.43x42 | VdWContact |
| PRO 2 | NTc.Cm34 | TRP 87 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TRP 87 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm34 | LEU 106 | 3.29x29 | Hydrophobic |
| PRO 2 | NTc.Cm34 | LEU 106 | 3.29x29 | VdWContact |
| PRO 2 | NTc.Cm34 | TYR 109 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TYR 278 | 7.43x42 | VdWContact |
| TYR 3 | NTc.Cm33 | TYR 109 | 3.32x32 | Hydrophobic |
| TYR 3 | NTc.Cm33 | PHE 247 | 6.51x51 | Hydrophobic |
| TYR 3 | NTc.Cm33 | PHE 247 | 6.51x51 | VdWContact |
| TYR 3 | NTc.Cm33 | LYS 251 | 6.55x55 | Hydrophobic |
| TYR 3 | NTc.Cm33 | ILE 270 | 7.35x34 | Hydrophobic |
| TYR 3 | NTc.Cm33 | GLU 274 | 7.39x38 | HBDonor |
| TYR 3 | NTc.Cm33 | GLU 274 | 7.39x38 | VdWContact |
| GLY 4 | NTc.Cm32 | GLU 274 | 7.39x38 | HBDonor |
| GLY 4 | NTc.Cm32 | GLU 274 | 7.39x38 | VdWContact |
| ALA 5 | NTc.Cm31 | LEU 34 | 1.35x35 | Hydrophobic |
| ALA 5 | NTc.Cm31 | TRP 87 | 2.60x60 | Hydrophobic |
| ASN 6 | NTc.Cm30 | ILE 179 | - | Hydrophobic |
| ASN 6 | NTc.Cm30 | ILE 179 | - | VdWContact |
| ASN 6 | NTc.Cm30 | CYS 180 | 45.50x50 | HBAcceptor |
| ASN 6 | NTc.Cm30 | CYS 180 | 45.50x50 | HBDonor |
| ASN 6 | NTc.Cm30 | CYS 180 | 45.50x50 | VdWContact |
| MET 7 | NTc.Cm29 | PHE 26 | 1.27x27 | Hydrophobic |
| MET 7 | NTc.Cm29 | PHE 26 | 1.27x27 | VdWContact |
| MET 7 | NTc.Cm29 | LYS 177 | - | HBAcceptor |
| MET 7 | NTc.Cm29 | LYS 177 | - | VdWContact |
| MET 7 | NTc.Cm29 | HIS 267 | 7.32x31 | Hydrophobic |
| MET 7 | NTc.Cm29 | HIS 267 | 7.32x31 | VdWContact |
| MET 7 | NTc.Cm29 | ILE 270 | 7.35x34 | Hydrophobic |
| MET 7 | NTc.Cm29 | MET 271 | 7.36x35 | Hydrophobic |
| GLU 8 | NTc.Cm28 | HIS 23 | - | HBAcceptor |
| GLU 8 | NTc.Cm28 | HIS 23 | - | VdWContact |
| GLU 8 | NTc.Cm28 | LEU 27 | 1.28x28 | VdWContact |
| GLU 8 | NTc.Cm28 | LEU 175 | - | Hydrophobic |
| GLU 8 | NTc.Cm28 | LEU 175 | - | VdWContact |
| GLU 8 | NTc.Cm28 | ASP 176 | - | VdWContact |
| ASP 9 | NTc.Cm27 | HIS 23 | - | VdWContact |
| ASP 9 | NTc.Cm27 | LEU 27 | 1.28x28 | Hydrophobic |
| ASP 9 | NTc.Cm27 | LEU 27 | 1.28x28 | VdWContact |
| ASP 9 | NTc.Cm27 | ASP 176 | - | HBDonor |
| ASP 9 | NTc.Cm27 | ASP 176 | - | VdWContact |
| ASP 9 | NTc.Cm27 | LYS 177 | - | Anionic |
| ASP 9 | NTc.Cm27 | LYS 177 | - | HBAcceptor |
| ASP 9 | NTc.Cm27 | LYS 177 | - | VdWContact |
| SER 10 | NTc.Cm26 | HIS 23 | - | HBAcceptor |
| SER 10 | NTc.Cm26 | HIS 23 | - | VdWContact |
| SER 10 | NTc.Cm26 | ASP 176 | - | HBDonor |
| SER 10 | NTc.Cm26 | ASP 176 | - | VdWContact |
| VAL 11 | NTc.Cm25 | HIS 23 | - | Hydrophobic |
| VAL 11 | NTc.Cm25 | ALA 262 | 7.27x26 | Hydrophobic |
| ARG 14 | NTc.Cm22 | TYR 261 | 7.26x25 | Hydrophobic |
| ARG 14 | NTc.Cm22 | TYR 261 | 7.26x25 | VdWContact |
| ASP 15 | NTc.Cm21 | TRP 258 | - | Hydrophobic |
| ASP 15 | NTc.Cm21 | TRP 258 | - | VdWContact |
| TYR 16 | NTc.Cm20 | TRP 258 | - | VdWContact |
| VAL 17 | NTc.Cm19 | TRP 258 | - | Hydrophobic |
| VAL 17 | NTc.Cm19 | TRP 258 | - | VdWContact |
| ARG 18 | NTc.Cm18 | GLU 185 | 5.32x33 | Cationic |
| TYR 19 | NTc.Cm17 | GLU 259 | 7.24x23 | VdWContact |
| LYS 27 | NTc.Cm9 | PHE 15 | - | VdWContact |
| HIS 28 | NTc.Cm8 | PHE 12 | - | HBDonor |
| HIS 28 | NTc.Cm8 | PHE 12 | - | Hydrophobic |
| HIS 28 | NTc.Cm8 | PHE 12 | - | VdWContact |
| HIS 28 | NTc.Cm8 | PHE 15 | - | Hydrophobic |
| HIS 28 | NTc.Cm8 | PHE 15 | - | VdWContact |
| PHE 29 | NTc.Cm7 | PHE 12 | - | Hydrophobic |
| PHE 29 | NTc.Cm7 | PHE 12 | - | VdWContact |
| TYR 30 | NTc.Cm6 | ASN 16 | - | Hydrophobic |
| TYR 30 | NTc.Cm6 | ASN 16 | - | VdWContact |
| PRO 37 | CX.5 | LEU 175 | - | Hydrophobic |
| PRO 37 | CX.5 | LEU 175 | - | VdWContact |
| VAL 42 | cxb1.7 | ALA 262 | 7.27x26 | Hydrophobic |
| LEU 44 | cxb1.10 | PHE 15 | - | Hydrophobic |
| GLU 50 | B1.2 | ALA 262 | 7.27x26 | Hydrophobic |
| GLU 50 | B1.2 | MET 263 | 7.28x27 | VdWContact |
| ILE 51 | B1.3 | TRP 258 | - | Hydrophobic |
| ILE 51 | B1.3 | GLU 259 | 7.24x23 | Hydrophobic |
| CYS 52 | B1.4 | TRP 258 | - | Hydrophobic |
| CYS 52 | B1.4 | TRP 258 | - | VdWContact |
| LEU 67 | B2.4 | PHE 12 | - | Hydrophobic |
| LEU 67 | B2.4 | PHE 12 | - | VdWContact |
| SER 68 | B2.5 | PHE 12 | - | VdWContact |
| GLN 69 | B2.6 | HIS 7 | - | HBAcceptor |
| GLN 69 | B2.6 | HIS 7 | - | VdWContact |
