Predicted complex interactions
CCL25_HUMAN + CXCR6
SUMMARY
- Chemokine
- CCL25_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR6 View partner entry
- Partner description
- UniProt: O00574; Gene: cxcr6_human; Family: Chemokine
- Interactions detected
- 92
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm29 | SER 14 | - | HBDonor |
| GLN 1 | NTc.Cm29 | SER 14 | - | VdWContact |
| GLN 1 | NTc.Cm29 | PHE 15 | - | VdWContact |
| GLN 1 | NTc.Cm29 | SER 18 | - | HBDonor |
| GLN 1 | NTc.Cm29 | SER 18 | - | VdWContact |
| GLY 2 | NTc.Cm28 | PHE 15 | - | HBDonor |
| GLY 2 | NTc.Cm28 | PHE 15 | - | VdWContact |
| GLY 2 | NTc.Cm28 | SER 19 | - | VdWContact |
| VAL 3 | NTc.Cm27 | PHE 15 | - | HBDonor |
| VAL 3 | NTc.Cm27 | PHE 15 | - | Hydrophobic |
| VAL 3 | NTc.Cm27 | PHE 15 | - | VdWContact |
| VAL 3 | NTc.Cm27 | SER 19 | - | HBDonor |
| VAL 3 | NTc.Cm27 | SER 19 | - | VdWContact |
| PHE 4 | NTc.Cm26 | SER 19 | - | VdWContact |
| GLU 5 | NTc.Cm25 | SER 19 | - | HBDonor |
| GLU 5 | NTc.Cm25 | SER 19 | - | VdWContact |
| GLU 5 | NTc.Cm25 | GLN 20 | - | HBAcceptor |
| GLU 5 | NTc.Cm25 | GLN 20 | - | Hydrophobic |
| GLU 5 | NTc.Cm25 | GLN 20 | - | VdWContact |
| GLU 5 | NTc.Cm25 | HIS 23 | - | HBAcceptor |
| GLU 5 | NTc.Cm25 | HIS 23 | - | Hydrophobic |
| GLU 5 | NTc.Cm25 | HIS 23 | - | VdWContact |
| GLU 5 | NTc.Cm25 | THR 264 | 7.29x28 | VdWContact |
| ASP 6 | NTc.Cm24 | MET 263 | 7.28x27 | VdWContact |
| CYS 7 | NTc.Cm23 | HIS 23 | - | Hydrophobic |
| CYS 7 | NTc.Cm23 | HIS 23 | - | VdWContact |
| LEU 9 | NTc.Cm21 | HIS 23 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | HIS 23 | - | VdWContact |
| LEU 9 | NTc.Cm21 | PHE 26 | 1.27x27 | Hydrophobic |
| LEU 9 | NTc.Cm21 | PHE 26 | 1.27x27 | VdWContact |
| LEU 9 | NTc.Cm21 | LEU 27 | 1.28x28 | Hydrophobic |
| LEU 9 | NTc.Cm21 | LEU 27 | 1.28x28 | VdWContact |
| LEU 9 | NTc.Cm21 | THR 264 | 7.29x28 | Hydrophobic |
| LEU 9 | NTc.Cm21 | HIS 267 | 7.32x31 | Hydrophobic |
| LEU 9 | NTc.Cm21 | HIS 267 | 7.32x31 | VdWContact |
| ALA 10 | NTc.Cm20 | TYR 261 | 7.26x25 | Hydrophobic |
| TYR 11 | NTc.Cm19 | LEU 175 | - | Hydrophobic |
| TYR 11 | NTc.Cm19 | LEU 175 | - | VdWContact |
| HIS 12 | NTc.Cm18 | ASP 184 | 5.31x32 | VdWContact |
| HIS 12 | NTc.Cm18 | TRP 258 | - | HBDonor |
| HIS 12 | NTc.Cm18 | TRP 258 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | TRP 258 | - | VdWContact |
| HIS 12 | NTc.Cm18 | TYR 261 | 7.26x25 | Hydrophobic |
| HIS 12 | NTc.Cm18 | TYR 261 | 7.26x25 | VdWContact |
| HIS 12 | NTc.Cm18 | ALA 262 | 7.27x26 | Hydrophobic |
| TYR 13 | NTc.Cm17 | PHE 173 | - | Hydrophobic |
| TYR 13 | NTc.Cm17 | LEU 175 | - | Hydrophobic |
| TYR 13 | NTc.Cm17 | HIS 183 | - | HBAcceptor |
| TYR 13 | NTc.Cm17 | HIS 183 | - | Hydrophobic |
| TYR 13 | NTc.Cm17 | HIS 183 | - | PiStacking |
| TYR 13 | NTc.Cm17 | HIS 183 | - | VdWContact |
| TYR 13 | NTc.Cm17 | ASP 184 | 5.31x32 | HBAcceptor |
| TYR 13 | NTc.Cm17 | ASP 184 | 5.31x32 | VdWContact |
| PRO 14 | NTc.Cm16 | HIS 183 | - | Hydrophobic |
| PRO 14 | NTc.Cm16 | HIS 183 | - | VdWContact |
| PRO 14 | NTc.Cm16 | ASP 184 | 5.31x32 | VdWContact |
| VAL 19 | NTc.Cm11 | TRP 258 | - | Hydrophobic |
| ARG 27 | NTc.Cm3 | ASN 16 | - | VdWContact |
| GLY 33 | cxb1.2 | GLN 24 | 1.25x25 | VdWContact |
| SER 34 | cxb1.5 | GLN 20 | - | VdWContact |
| SER 34 | cxb1.5 | HIS 23 | - | VdWContact |
| SER 34 | cxb1.5 | GLN 24 | 1.25x25 | VdWContact |
| SER 34 | cxb1.5 | LEU 27 | 1.28x28 | VdWContact |
| CYS 35 | cxb1.7 | HIS 23 | - | Hydrophobic |
| ASN 36 | cxb1.8 | LEU 27 | 1.28x28 | Hydrophobic |
| ASN 36 | cxb1.8 | LEU 27 | 1.28x28 | VdWContact |
| ASN 36 | cxb1.8 | LYS 31 | 1.32x32 | VdWContact |
| LEU 37 | cxb1.10 | LEU 175 | - | VdWContact |
| LEU 37 | cxb1.10 | ASP 176 | - | Hydrophobic |
| LEU 44 | B1.3 | TRP 258 | - | Hydrophobic |
| LEU 44 | B1.3 | TRP 258 | - | VdWContact |
| ARG 47 | B1.6 | HIS 257 | 6.61x61 | VdWContact |
| ARG 47 | B1.6 | GLU 259 | 7.24x23 | Cationic |
| ARG 47 | B1.6 | GLU 259 | 7.24x23 | HBDonor |
| ARG 47 | B1.6 | GLU 259 | 7.24x23 | VdWContact |
| ARG 49 | b1b2.1 | TRP 258 | - | CationPi |
| ARG 49 | b1b2.1 | TRP 258 | - | Hydrophobic |
| ARG 49 | b1b2.1 | TRP 258 | - | VdWContact |
| ARG 49 | b1b2.1 | GLU 259 | 7.24x23 | Cationic |
| ARG 49 | b1b2.1 | GLU 259 | 7.24x23 | HBDonor |
| ARG 49 | b1b2.1 | GLU 259 | 7.24x23 | Hydrophobic |
| ARG 49 | b1b2.1 | GLU 259 | 7.24x23 | VdWContact |
| LYS 50 | b1b2.2 | ALA 262 | 7.27x26 | HBDonor |
| LYS 50 | b1b2.2 | ALA 262 | 7.27x26 | Hydrophobic |
| LYS 50 | b1b2.2 | ALA 262 | 7.27x26 | VdWContact |
| VAL 51 | b1b2.3 | TRP 258 | - | Hydrophobic |
| VAL 51 | b1b2.3 | TRP 258 | - | VdWContact |
| ASN 54 | b1b2.6 | ASP 176 | - | HBDonor |
| ASN 54 | b1b2.6 | ASP 176 | - | VdWContact |
| LYS 56 | b1b2.9 | ASP 176 | - | Cationic |
| LYS 56 | b1b2.9 | ASP 176 | - | HBDonor |
| LYS 56 | b1b2.9 | ASP 176 | - | VdWContact |
