Predicted complex interactions
CCL16_HUMAN + ACKR3
SUMMARY
- Chemokine
- CCL16_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR3 View partner entry
- Partner description
- UniProt: P25106; Gene: ackr3_human; Family: Chemokine
- Interactions detected
- 122
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm36 | TRP 100 | 2.60x60 | VdWContact |
| GLN 1 | NTc.Cm36 | HIS 121 | 3.29x29 | Hydrophobic |
| GLN 1 | NTc.Cm36 | HIS 121 | 3.29x29 | VdWContact |
| GLN 1 | NTc.Cm36 | PHE 124 | 3.32x32 | Hydrophobic |
| GLN 1 | NTc.Cm36 | ASP 179 | 4.60x61 | Cationic |
| GLN 1 | NTc.Cm36 | ASP 179 | 4.60x61 | HBDonor |
| PRO 2 | NTc.Cm35 | TYR 268 | 6.51x51 | Hydrophobic |
| PRO 2 | NTc.Cm35 | TYR 268 | 6.51x51 | VdWContact |
| PRO 2 | NTc.Cm35 | LEU 297 | 7.35x34 | Hydrophobic |
| PRO 2 | NTc.Cm35 | LEU 297 | 7.35x34 | VdWContact |
| LYS 3 | NTc.Cm34 | LEU 209 | 5.35x36 | Hydrophobic |
| LYS 3 | NTc.Cm34 | LEU 209 | 5.35x36 | VdWContact |
| VAL 4 | NTc.Cm33 | ASN 108 | - | VdWContact |
| VAL 4 | NTc.Cm33 | PHE 294 | 7.32x31 | Hydrophobic |
| VAL 4 | NTc.Cm33 | PHE 294 | 7.32x31 | VdWContact |
| VAL 4 | NTc.Cm33 | HIS 298 | 7.36x35 | Hydrophobic |
| VAL 4 | NTc.Cm33 | HIS 298 | 7.36x35 | VdWContact |
| PRO 5 | NTc.Cm32 | LEU 293 | 7.31x30 | Hydrophobic |
| PRO 5 | NTc.Cm32 | PHE 294 | 7.32x31 | Hydrophobic |
| PRO 5 | NTc.Cm32 | PHE 294 | 7.32x31 | VdWContact |
| PRO 5 | NTc.Cm32 | LEU 297 | 7.35x34 | Hydrophobic |
| PRO 5 | NTc.Cm32 | LEU 297 | 7.35x34 | VdWContact |
| GLU 6 | NTc.Cm31 | ARG 197 | 45.51x51 | Anionic |
| GLU 6 | NTc.Cm31 | ARG 197 | 45.51x51 | HBAcceptor |
| GLU 6 | NTc.Cm31 | ARG 197 | 45.51x51 | VdWContact |
| TRP 7 | NTc.Cm30 | CYS 34 | - | Hydrophobic |
| TRP 7 | NTc.Cm30 | CYS 34 | - | VdWContact |
| TRP 7 | NTc.Cm30 | CYS 287 | 7.25x24 | VdWContact |
| TRP 7 | NTc.Cm30 | GLU 290 | 7.28x27 | Hydrophobic |
| TRP 7 | NTc.Cm30 | GLU 290 | 7.28x27 | VdWContact |
| TRP 7 | NTc.Cm30 | HIS 291 | 7.29x28 | Hydrophobic |
| TRP 7 | NTc.Cm30 | HIS 291 | 7.29x28 | VdWContact |
| VAL 8 | NTc.Cm29 | MET 37 | - | Hydrophobic |
| VAL 8 | NTc.Cm29 | LYS 40 | - | HBAcceptor |
| VAL 8 | NTc.Cm29 | LYS 40 | - | Hydrophobic |
| VAL 8 | NTc.Cm29 | LYS 40 | - | VdWContact |
| VAL 8 | NTc.Cm29 | PHE 294 | 7.32x31 | Hydrophobic |
| VAL 8 | NTc.Cm29 | PHE 294 | 7.32x31 | VdWContact |
| ASN 9 | NTc.Cm28 | LYS 40 | - | HBAcceptor |
| ASN 9 | NTc.Cm28 | LYS 40 | - | VdWContact |
| ASN 9 | NTc.Cm28 | ASN 108 | - | VdWContact |
| ASN 9 | NTc.Cm28 | TYR 195 | - | Hydrophobic |
| ASN 9 | NTc.Cm28 | TYR 195 | - | VdWContact |
| ASN 9 | NTc.Cm28 | ARG 197 | 45.51x51 | VdWContact |
| THR 10 | NTc.Cm27 | TYR 195 | - | Hydrophobic |
| THR 13 | NTc.Cm24 | THR 31 | - | Hydrophobic |
| THR 13 | NTc.Cm24 | THR 31 | - | VdWContact |
| CYS 14 | NTc.Cm23 | VAL 32 | - | HBAcceptor |
| CYS 14 | NTc.Cm23 | VAL 32 | - | HBDonor |
| CYS 14 | NTc.Cm23 | VAL 32 | - | VdWContact |
| CYS 14 | NTc.Cm23 | PHE 285 | - | Hydrophobic |
| LEU 16 | NTc.Cm21 | ASP 30 | - | HBDonor |
| LEU 16 | NTc.Cm21 | ASP 30 | - | Hydrophobic |
| LEU 16 | NTc.Cm21 | ASP 30 | - | VdWContact |
| LEU 16 | NTc.Cm21 | VAL 32 | - | Hydrophobic |
| LEU 16 | NTc.Cm21 | VAL 32 | - | VdWContact |
| LEU 16 | NTc.Cm21 | PHE 285 | - | Hydrophobic |
| LEU 16 | NTc.Cm21 | PHE 285 | - | VdWContact |
| TYR 18 | NTc.Cm19 | LYS 206 | 5.32x33 | VdWContact |
| TYR 19 | NTc.Cm18 | ILE 27 | - | Hydrophobic |
| TYR 19 | NTc.Cm18 | ILE 27 | - | VdWContact |
| LYS 21 | NTc.Cm16 | ASP 25 | - | Cationic |
| LYS 21 | NTc.Cm16 | ASP 25 | - | HBDonor |
| LYS 21 | NTc.Cm16 | ASP 25 | - | VdWContact |
| LEU 23 | NTc.Cm14 | ILE 27 | - | Hydrophobic |
| LEU 27 | NTc.Cm10 | TRP 19 | - | Hydrophobic |
| VAL 29 | NTc.Cm8 | PHE 14 | - | Hydrophobic |
| LYS 33 | NTc.Cm4 | GLU 202 | - | Cationic |
| LYS 33 | NTc.Cm4 | GLU 202 | - | VdWContact |
| LEU 35 | NTc.Cm2 | GLU 202 | - | Hydrophobic |
| LEU 35 | NTc.Cm2 | ILE 205 | 5.31x32 | Hydrophobic |
| LEU 35 | NTc.Cm2 | ILE 205 | 5.31x32 | VdWContact |
| ASN 36 | NTc.Cm1 | ARG 197 | 45.51x51 | VdWContact |
| HIS 38 | CX.5 | SER 278 | 6.61x61 | HBDonor |
| HIS 38 | CX.5 | SER 278 | 6.61x61 | VdWContact |
| HIS 38 | CX.5 | ILE 279 | 6.62x62 | Hydrophobic |
| HIS 38 | CX.5 | ILE 279 | 6.62x62 | VdWContact |
| HIS 38 | CX.5 | PHE 285 | - | Hydrophobic |
| HIS 38 | CX.5 | PHE 285 | - | VdWContact |
| LEU 39 | cxb1.1 | LYS 206 | 5.32x33 | VdWContact |
| LEU 39 | cxb1.1 | HIS 281 | 6.64x64 | Hydrophobic |
| LEU 39 | cxb1.1 | HIS 281 | 6.64x64 | VdWContact |
| PRO 40 | cxb1.2 | ILE 205 | 5.31x32 | Hydrophobic |
| PRO 40 | cxb1.2 | LYS 206 | 5.32x33 | Hydrophobic |
| PRO 40 | cxb1.2 | LYS 206 | 5.32x33 | VdWContact |
| ILE 43 | cxb1.7 | THR 31 | - | Hydrophobic |
| LYS 47 | cxb1.14 | PHE 14 | - | VdWContact |
| LYS 47 | cxb1.14 | ILE 17 | - | VdWContact |
| ARG 48 | cxb1.15 | PHE 14 | - | VdWContact |
| ARG 48 | cxb1.15 | ILE 17 | - | HBDonor |
| ARG 48 | cxb1.15 | ILE 17 | - | Hydrophobic |
| ARG 48 | cxb1.15 | ILE 17 | - | VdWContact |
| ARG 48 | cxb1.15 | SER 18 | - | HBDonor |
| ARG 48 | cxb1.15 | SER 18 | - | VdWContact |
| ARG 48 | cxb1.15 | TRP 19 | - | CationPi |
| ARG 48 | cxb1.15 | TRP 19 | - | VdWContact |
| ASN 49 | cxb1.16 | PHE 14 | - | Hydrophobic |
| ASN 49 | cxb1.16 | PHE 14 | - | VdWContact |
| ARG 50 | B1.1 | CYS 21 | - | Cationic |
| ARG 50 | B1.1 | VAL 29 | - | Hydrophobic |
| GLU 51 | B1.2 | VAL 29 | - | Hydrophobic |
| GLU 51 | B1.2 | VAL 29 | - | VdWContact |
| GLU 51 | B1.2 | THR 31 | - | Hydrophobic |
| VAL 52 | B1.3 | ILE 27 | - | Hydrophobic |
| VAL 52 | B1.3 | VAL 29 | - | Hydrophobic |
| CYS 53 | B1.4 | THR 31 | - | VdWContact |
| PRO 56 | B1.7 | GLU 202 | - | VdWContact |
| ASN 57 | b1b2.4 | HIS 203 | - | VdWContact |
| ASN 57 | b1b2.4 | GLU 207 | 5.33x34 | HBDonor |
| ASN 57 | b1b2.4 | GLU 207 | 5.33x34 | VdWContact |
| PRO 71 | b2b3.4 | TYR 8 | - | Hydrophobic |
| PRO 71 | b2b3.4 | TYR 8 | - | VdWContact |
| LEU 73 | b2b3.12 | TYR 8 | - | Hydrophobic |
| ASN 77 | B3.4 | SER 190 | - | HBDonor |
| ASN 77 | B3.4 | SER 190 | - | VdWContact |
| LEU 78 | b3h.1 | MET 33 | - | Hydrophobic |
| LEU 78 | b3h.1 | MET 33 | - | VdWContact |
| LYS 82 | H.1 | SER 9 | - | HBDonor |
| LYS 82 | H.1 | SER 9 | - | VdWContact |
| LYS 82 | H.1 | PRO 11 | - | Hydrophobic |
| ILE 84 | H.3 | PRO 11 | - | Hydrophobic |
| ILE 84 | H.3 | PRO 11 | - | VdWContact |
