Predicted complex interactions
CCL3_HUMAN + CXCR6
SUMMARY
- Chemokine
- CCL3_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR6 View partner entry
- Partner description
- UniProt: O00574; Gene: cxcr6_human; Family: Chemokine
- Interactions detected
- 81
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm33 | TYR 38 | 1.39x39 | HBDonor |
| SER 1 | NTc.Cm33 | TYR 38 | 1.39x39 | VdWContact |
| SER 1 | NTc.Cm33 | TRP 87 | 2.60x60 | VdWContact |
| SER 1 | NTc.Cm33 | GLU 274 | 7.39x38 | HBDonor |
| SER 1 | NTc.Cm33 | GLU 274 | 7.39x38 | VdWContact |
| LEU 2 | NTc.Cm32 | PHE 247 | 6.51x51 | Hydrophobic |
| LEU 2 | NTc.Cm32 | LYS 251 | 6.55x55 | Hydrophobic |
| LEU 2 | NTc.Cm32 | LYS 251 | 6.55x55 | VdWContact |
| LEU 2 | NTc.Cm32 | ARG 254 | 6.58x58 | VdWContact |
| LEU 2 | NTc.Cm32 | ILE 270 | 7.35x34 | Hydrophobic |
| LEU 2 | NTc.Cm32 | GLU 274 | 7.39x38 | HBDonor |
| LEU 2 | NTc.Cm32 | GLU 274 | 7.39x38 | VdWContact |
| ALA 3 | NTc.Cm31 | LEU 34 | 1.35x35 | Hydrophobic |
| ALA 3 | NTc.Cm31 | LEU 34 | 1.35x35 | VdWContact |
| ALA 3 | NTc.Cm31 | ILE 270 | 7.35x34 | Hydrophobic |
| ALA 3 | NTc.Cm31 | MET 271 | 7.36x35 | Hydrophobic |
| ALA 3 | NTc.Cm31 | MET 271 | 7.36x35 | VdWContact |
| ALA 3 | NTc.Cm31 | GLU 274 | 7.39x38 | HBDonor |
| ALA 3 | NTc.Cm31 | GLU 274 | 7.39x38 | VdWContact |
| ASP 5 | NTc.Cm29 | ILE 179 | - | Hydrophobic |
| ASP 5 | NTc.Cm29 | ILE 179 | - | VdWContact |
| ASP 5 | NTc.Cm29 | CYS 180 | 45.50x50 | VdWContact |
| THR 6 | NTc.Cm28 | PHE 26 | 1.27x27 | Hydrophobic |
| THR 6 | NTc.Cm28 | PHE 26 | 1.27x27 | VdWContact |
| THR 6 | NTc.Cm28 | HIS 267 | 7.32x31 | Hydrophobic |
| THR 6 | NTc.Cm28 | HIS 267 | 7.32x31 | VdWContact |
| PRO 7 | NTc.Cm27 | HIS 23 | - | HBAcceptor |
| PRO 7 | NTc.Cm27 | HIS 23 | - | VdWContact |
| PRO 7 | NTc.Cm27 | LEU 175 | - | Hydrophobic |
| PRO 7 | NTc.Cm27 | LEU 175 | - | VdWContact |
| THR 8 | NTc.Cm26 | LEU 27 | 1.28x28 | Hydrophobic |
| THR 8 | NTc.Cm26 | LEU 27 | 1.28x28 | VdWContact |
| THR 8 | NTc.Cm26 | ASP 176 | - | HBDonor |
| THR 8 | NTc.Cm26 | ASP 176 | - | VdWContact |
| THR 8 | NTc.Cm26 | LYS 177 | - | VdWContact |
| ALA 9 | NTc.Cm25 | HIS 23 | - | Hydrophobic |
| ALA 9 | NTc.Cm25 | HIS 23 | - | VdWContact |
| CYS 10 | NTc.Cm24 | LEU 175 | - | Hydrophobic |
| CYS 10 | NTc.Cm24 | LEU 175 | - | VdWContact |
| CYS 10 | NTc.Cm24 | ASP 176 | - | VdWContact |
| PHE 12 | NTc.Cm22 | PHE 173 | - | Hydrophobic |
| PHE 12 | NTc.Cm22 | PHE 173 | - | VdWContact |
| PHE 12 | NTc.Cm22 | LEU 175 | - | Hydrophobic |
| PHE 12 | NTc.Cm22 | LEU 175 | - | VdWContact |
| PHE 12 | NTc.Cm22 | ILE 179 | - | Hydrophobic |
| PHE 12 | NTc.Cm22 | ILE 179 | - | VdWContact |
| PHE 12 | NTc.Cm22 | HIS 183 | - | Hydrophobic |
| PHE 12 | NTc.Cm22 | HIS 183 | - | VdWContact |
| SER 13 | NTc.Cm21 | ASP 184 | 5.31x32 | HBDonor |
| SER 13 | NTc.Cm21 | ASP 184 | 5.31x32 | VdWContact |
| ASP 26 | NTc.Cm7 | ASN 16 | - | HBAcceptor |
| ASP 26 | NTc.Cm7 | ASN 16 | - | VdWContact |
| GLN 33 | CX.1 | ASP 176 | - | Hydrophobic |
| GLN 33 | CX.1 | ASP 176 | - | VdWContact |
| CYS 34 | CX.5 | LEU 175 | - | VdWContact |
| CYS 34 | CX.5 | ASP 176 | - | VdWContact |
| SER 35 | cxb1.1 | ASN 174 | - | HBDonor |
| SER 35 | cxb1.1 | ASN 174 | - | VdWContact |
| SER 35 | cxb1.1 | LEU 175 | - | HBDonor |
| SER 35 | cxb1.1 | LEU 175 | - | VdWContact |
| THR 43 | cxb1.14 | TRP 258 | - | Hydrophobic |
| ARG 45 | cxb1.16 | GLU 259 | 7.24x23 | Cationic |
| ARG 45 | cxb1.16 | MET 263 | 7.28x27 | VdWContact |
| SER 46 | B1.1 | MET 263 | 7.28x27 | VdWContact |
| ARG 47 | B1.2 | HIS 257 | 6.61x61 | VdWContact |
| ARG 47 | B1.2 | TRP 258 | - | CationPi |
| ARG 47 | B1.2 | TRP 258 | - | Hydrophobic |
| ARG 47 | B1.2 | TRP 258 | - | VdWContact |
| ARG 47 | B1.2 | GLU 259 | 7.24x23 | Cationic |
| ARG 47 | B1.2 | GLU 259 | 7.24x23 | HBDonor |
| ARG 47 | B1.2 | GLU 259 | 7.24x23 | Hydrophobic |
| ARG 47 | B1.2 | GLU 259 | 7.24x23 | VdWContact |
| GLN 48 | B1.3 | ALA 262 | 7.27x26 | Hydrophobic |
| GLN 48 | B1.3 | ALA 262 | 7.27x26 | VdWContact |
| VAL 49 | B1.4 | TRP 258 | - | Hydrophobic |
| VAL 49 | B1.4 | TRP 258 | - | VdWContact |
| SER 68 | b2b3.4 | PHE 12 | - | VdWContact |
| ALA 69 | b2b3.11 | TYR 10 | - | VdWContact |
| ALA 69 | b2b3.11 | PHE 12 | - | HBAcceptor |
| ALA 69 | b2b3.11 | PHE 12 | - | Hydrophobic |
| ALA 69 | b2b3.11 | PHE 12 | - | VdWContact |
