Predicted complex interactions
CCL8_HUMAN + CXCR6
SUMMARY
- Chemokine
- CCL8_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR6 View partner entry
- Partner description
- UniProt: O00574; Gene: cxcr6_human; Family: Chemokine
- Interactions detected
- 84
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm33 | TRP 87 | 2.60x60 | Hydrophobic |
| GLN 1 | NTc.Cm33 | LEU 106 | 3.29x29 | Hydrophobic |
| GLN 1 | NTc.Cm33 | CYS 180 | 45.50x50 | VdWContact |
| GLN 1 | NTc.Cm33 | GLY 181 | 45.51x51 | VdWContact |
| PRO 2 | NTc.Cm32 | TRP 87 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TRP 87 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm32 | TYR 109 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm32 | GLU 274 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm32 | TYR 278 | 7.43x42 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TYR 278 | 7.43x42 | VdWContact |
| ASP 3 | NTc.Cm31 | LYS 251 | 6.55x55 | Anionic |
| ASP 3 | NTc.Cm31 | LYS 251 | 6.55x55 | HBAcceptor |
| ASP 3 | NTc.Cm31 | LYS 251 | 6.55x55 | VdWContact |
| ASP 3 | NTc.Cm31 | ARG 254 | 6.58x58 | Anionic |
| ASP 3 | NTc.Cm31 | ARG 254 | 6.58x58 | HBAcceptor |
| ASP 3 | NTc.Cm31 | ARG 254 | 6.58x58 | VdWContact |
| ASP 3 | NTc.Cm31 | ILE 270 | 7.35x34 | Hydrophobic |
| ASP 3 | NTc.Cm31 | GLU 274 | 7.39x38 | HBDonor |
| ASP 3 | NTc.Cm31 | GLU 274 | 7.39x38 | VdWContact |
| SER 4 | NTc.Cm30 | LEU 34 | 1.35x35 | VdWContact |
| SER 4 | NTc.Cm30 | GLU 274 | 7.39x38 | HBDonor |
| SER 4 | NTc.Cm30 | GLU 274 | 7.39x38 | VdWContact |
| VAL 5 | NTc.Cm29 | LEU 34 | 1.35x35 | Hydrophobic |
| VAL 5 | NTc.Cm29 | TRP 87 | 2.60x60 | Hydrophobic |
| VAL 5 | NTc.Cm29 | ALA 90 | 2.63x63 | Hydrophobic |
| VAL 5 | NTc.Cm29 | LYS 177 | - | HBAcceptor |
| VAL 5 | NTc.Cm29 | LYS 177 | - | VdWContact |
| SER 6 | NTc.Cm28 | ILE 179 | - | VdWContact |
| ILE 7 | NTc.Cm27 | PHE 26 | 1.27x27 | Hydrophobic |
| ILE 7 | NTc.Cm27 | PHE 26 | 1.27x27 | VdWContact |
| ILE 7 | NTc.Cm27 | HIS 267 | 7.32x31 | Hydrophobic |
| ILE 7 | NTc.Cm27 | HIS 267 | 7.32x31 | VdWContact |
| ILE 7 | NTc.Cm27 | MET 271 | 7.36x35 | Hydrophobic |
| ILE 9 | NTc.Cm25 | HIS 23 | - | HBAcceptor |
| ILE 9 | NTc.Cm25 | HIS 23 | - | VdWContact |
| ILE 9 | NTc.Cm25 | LEU 27 | 1.28x28 | Hydrophobic |
| ILE 9 | NTc.Cm25 | LEU 27 | 1.28x28 | VdWContact |
| ILE 9 | NTc.Cm25 | ASP 176 | - | HBDonor |
| ILE 9 | NTc.Cm25 | ASP 176 | - | VdWContact |
| ILE 9 | NTc.Cm25 | LYS 177 | - | Hydrophobic |
| ILE 9 | NTc.Cm25 | LYS 177 | - | VdWContact |
| THR 10 | NTc.Cm24 | ASP 176 | - | HBDonor |
| THR 10 | NTc.Cm24 | ASP 176 | - | VdWContact |
| PHE 13 | NTc.Cm21 | SER 19 | - | VdWContact |
| PHE 13 | NTc.Cm21 | GLN 20 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | HIS 23 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | HIS 23 | - | VdWContact |
| ASN 14 | NTc.Cm20 | ASN 16 | - | HBDonor |
| ASN 14 | NTc.Cm20 | ASN 16 | - | Hydrophobic |
| ASN 14 | NTc.Cm20 | ASN 16 | - | VdWContact |
| ILE 16 | NTc.Cm18 | TYR 10 | - | Hydrophobic |
| ILE 16 | NTc.Cm18 | TYR 10 | - | VdWContact |
| ARG 18 | NTc.Cm16 | GLU 8 | - | Cationic |
| ARG 18 | NTc.Cm16 | GLU 8 | - | HBDonor |
| ARG 18 | NTc.Cm16 | GLU 8 | - | VdWContact |
| ARG 18 | NTc.Cm16 | ASP 9 | - | HBDonor |
| ARG 18 | NTc.Cm16 | ASP 9 | - | VdWContact |
| ARG 18 | NTc.Cm16 | TYR 10 | - | CationPi |
| ARG 18 | NTc.Cm16 | TYR 10 | - | HBDonor |
| ARG 18 | NTc.Cm16 | TYR 10 | - | Hydrophobic |
| ARG 18 | NTc.Cm16 | TYR 10 | - | VdWContact |
| ILE 20 | NTc.Cm14 | TYR 10 | - | Hydrophobic |
| ARG 24 | NTc.Cm10 | GLU 8 | - | Cationic |
| ARG 24 | NTc.Cm10 | GLU 8 | - | HBDonor |
| ARG 24 | NTc.Cm10 | GLU 8 | - | VdWContact |
| ARG 24 | NTc.Cm10 | TYR 10 | - | HBDonor |
| ARG 24 | NTc.Cm10 | TYR 10 | - | VdWContact |
| ILE 31 | NTc.Cm3 | ASP 176 | - | Hydrophobic |
| ASN 33 | NTc.Cm1 | LEU 175 | - | Hydrophobic |
| ASN 33 | NTc.Cm1 | LEU 175 | - | VdWContact |
| ASN 33 | NTc.Cm1 | ASP 176 | - | HBDonor |
| ASN 33 | NTc.Cm1 | ASP 176 | - | VdWContact |
| ILE 34 | CX.1 | HIS 183 | - | Hydrophobic |
| GLN 35 | CX.5 | TYR 261 | 7.26x25 | Hydrophobic |
| GLN 35 | CX.5 | TYR 261 | 7.26x25 | VdWContact |
| GLN 35 | CX.5 | ALA 262 | 7.27x26 | VdWContact |
| GLN 35 | CX.5 | HIS 267 | 7.32x31 | Hydrophobic |
| GLN 35 | CX.5 | HIS 267 | 7.32x31 | VdWContact |
| PRO 37 | cxb1.2 | ALA 262 | 7.27x26 | Hydrophobic |
| PRO 37 | cxb1.2 | ALA 262 | 7.27x26 | VdWContact |
| ARG 47 | B1.1 | ASP 5 | - | Cationic |
| ARG 47 | B1.1 | ASP 5 | - | HBDonor |
| ARG 47 | B1.1 | ASP 5 | - | VdWContact |
| VAL 51 | B1.5 | PHE 12 | - | Hydrophobic |
