Predicted complex interactions
CXCL10_HUMAN + CXCR6
SUMMARY
- Chemokine
- CXCL10_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR6 View partner entry
- Partner description
- UniProt: O00574; Gene: cxcr6_human; Family: Chemokine
- Interactions detected
- 90
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm29 | LEU 106 | 3.29x29 | Hydrophobic |
| VAL 1 | NTc.Cm29 | LEU 106 | 3.29x29 | VdWContact |
| VAL 1 | NTc.Cm29 | TYR 109 | 3.32x32 | Hydrophobic |
| VAL 1 | NTc.Cm29 | TYR 109 | 3.32x32 | VdWContact |
| VAL 1 | NTc.Cm29 | TYR 182 | 45.52x52 | Hydrophobic |
| VAL 1 | NTc.Cm29 | TYR 278 | 7.43x42 | VdWContact |
| PRO 2 | NTc.Cm28 | LEU 34 | 1.35x35 | Hydrophobic |
| PRO 2 | NTc.Cm28 | TYR 38 | 1.39x39 | Hydrophobic |
| PRO 2 | NTc.Cm28 | TYR 38 | 1.39x39 | VdWContact |
| PRO 2 | NTc.Cm28 | TRP 87 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm28 | TRP 87 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm28 | GLU 274 | 7.39x38 | VdWContact |
| LEU 3 | NTc.Cm27 | PHE 247 | 6.51x51 | Hydrophobic |
| LEU 3 | NTc.Cm27 | LYS 251 | 6.55x55 | Hydrophobic |
| LEU 3 | NTc.Cm27 | LYS 251 | 6.55x55 | VdWContact |
| LEU 3 | NTc.Cm27 | ARG 254 | 6.58x58 | VdWContact |
| LEU 3 | NTc.Cm27 | ILE 270 | 7.35x34 | Hydrophobic |
| LEU 3 | NTc.Cm27 | GLU 274 | 7.39x38 | HBDonor |
| LEU 3 | NTc.Cm27 | GLU 274 | 7.39x38 | VdWContact |
| SER 4 | NTc.Cm26 | LEU 34 | 1.35x35 | VdWContact |
| ARG 5 | NTc.Cm25 | LEU 34 | 1.35x35 | Hydrophobic |
| ARG 5 | NTc.Cm25 | LEU 34 | 1.35x35 | VdWContact |
| ARG 5 | NTc.Cm25 | PRO 35 | 1.36x36 | VdWContact |
| ARG 5 | NTc.Cm25 | TRP 87 | 2.60x60 | VdWContact |
| ARG 5 | NTc.Cm25 | ALA 88 | 2.61x61 | HBDonor |
| ARG 5 | NTc.Cm25 | ALA 88 | 2.61x61 | VdWContact |
| ARG 5 | NTc.Cm25 | ALA 90 | 2.63x63 | HBDonor |
| ARG 5 | NTc.Cm25 | ALA 90 | 2.63x63 | VdWContact |
| ARG 5 | NTc.Cm25 | GLY 91 | 2.64x64 | VdWContact |
| ARG 5 | NTc.Cm25 | ILE 179 | - | VdWContact |
| VAL 7 | NTc.Cm23 | ILE 179 | - | Hydrophobic |
| VAL 7 | NTc.Cm23 | ILE 179 | - | VdWContact |
| ARG 8 | NTc.Cm22 | HIS 23 | - | VdWContact |
| ARG 8 | NTc.Cm22 | LEU 27 | 1.28x28 | Hydrophobic |
| ARG 8 | NTc.Cm22 | HIS 267 | 7.32x31 | CationPi |
| ARG 8 | NTc.Cm22 | HIS 267 | 7.32x31 | HBDonor |
| ARG 8 | NTc.Cm22 | HIS 267 | 7.32x31 | Hydrophobic |
| ARG 8 | NTc.Cm22 | HIS 267 | 7.32x31 | VdWContact |
| ARG 8 | NTc.Cm22 | ILE 270 | 7.35x34 | VdWContact |
| CYS 9 | NTc.Cm21 | TYR 261 | 7.26x25 | VdWContact |
| THR 10 | NTc.Cm20 | TYR 261 | 7.26x25 | VdWContact |
| THR 10 | NTc.Cm20 | ALA 262 | 7.27x26 | VdWContact |
| ILE 12 | NTc.Cm18 | ARG 254 | 6.58x58 | Anionic |
| ILE 12 | NTc.Cm18 | ARG 254 | 6.58x58 | VdWContact |
| ILE 12 | NTc.Cm18 | TYR 261 | 7.26x25 | VdWContact |
| SER 13 | NTc.Cm17 | GLU 185 | 5.32x33 | HBDonor |
| SER 13 | NTc.Cm17 | GLU 185 | 5.32x33 | VdWContact |
| LYS 26 | NTc.Cm4 | SER 13 | - | VdWContact |
| GLU 28 | NTc.Cm2 | PHE 15 | - | Hydrophobic |
| ILE 29 | NTc.Cm1 | PHE 15 | - | Hydrophobic |
| ILE 29 | NTc.Cm1 | PHE 15 | - | VdWContact |
| GLN 34 | cxb1.2 | LYS 177 | - | HBAcceptor |
| GLN 34 | cxb1.2 | LYS 177 | - | VdWContact |
| PHE 35 | cxb1.5 | GLN 24 | 1.25x25 | Hydrophobic |
| PHE 35 | cxb1.5 | LEU 27 | 1.28x28 | Hydrophobic |
| PHE 35 | cxb1.5 | LEU 27 | 1.28x28 | VdWContact |
| PHE 35 | cxb1.5 | GLN 28 | 1.29x29 | Hydrophobic |
| PHE 35 | cxb1.5 | GLN 28 | 1.29x29 | VdWContact |
| PHE 35 | cxb1.5 | LYS 31 | 1.32x32 | Hydrophobic |
| PRO 37 | cxb1.7 | LEU 175 | - | Hydrophobic |
| PRO 37 | cxb1.7 | LEU 175 | - | VdWContact |
| PRO 37 | cxb1.7 | ASP 176 | - | HBAcceptor |
| PRO 37 | cxb1.7 | ASP 176 | - | Hydrophobic |
| PRO 37 | cxb1.7 | ASP 176 | - | VdWContact |
| PRO 37 | cxb1.7 | ILE 179 | - | Hydrophobic |
| PRO 37 | cxb1.7 | ILE 179 | - | VdWContact |
| ARG 38 | cxb1.8 | LEU 175 | - | Hydrophobic |
| ARG 38 | cxb1.8 | LEU 175 | - | VdWContact |
| ARG 38 | cxb1.8 | ASP 184 | 5.31x32 | Cationic |
| ARG 38 | cxb1.8 | ASP 184 | 5.31x32 | HBDonor |
| ARG 38 | cxb1.8 | ASP 184 | 5.31x32 | VdWContact |
| ILE 42 | cxb1.15 | TRP 258 | - | Hydrophobic |
| ILE 42 | cxb1.15 | ALA 262 | 7.27x26 | Hydrophobic |
| LYS 46 | B1.3 | GLU 8 | - | Cationic |
| LYS 51 | b1b2.4 | TRP 258 | - | Hydrophobic |
| LYS 51 | b1b2.4 | TRP 258 | - | VdWContact |
| LYS 51 | b1b2.4 | GLU 259 | 7.24x23 | HBDonor |
| LYS 51 | b1b2.4 | GLU 259 | 7.24x23 | Hydrophobic |
| LYS 51 | b1b2.4 | GLU 259 | 7.24x23 | VdWContact |
| CYS 53 | b1b2.7 | TRP 258 | - | Hydrophobic |
| CYS 53 | b1b2.7 | TRP 258 | - | VdWContact |
| VAL 68 | b2b3.3 | PHE 12 | - | Hydrophobic |
| VAL 68 | b2b3.3 | PHE 12 | - | VdWContact |
| ARG 72 | B3.1 | PHE 12 | - | VdWContact |
| ARG 75 | B3.4 | HIS 7 | - | VdWContact |
| ARG 75 | B3.4 | GLU 8 | - | HBDonor |
| ARG 75 | B3.4 | GLU 8 | - | VdWContact |
| ARG 75 | B3.4 | ASP 9 | - | Cationic |
| ARG 75 | B3.4 | ASP 9 | - | HBDonor |
| ARG 75 | B3.4 | ASP 9 | - | VdWContact |
