Predicted complex interactions
CCL17_HUMAN + ACKR3
SUMMARY
- Chemokine
- CCL17_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR3 View partner entry
- Partner description
- UniProt: P25106; Gene: ackr3_human; Family: Chemokine
- Interactions detected
- 124
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm32 | PHE 124 | 3.32x32 | Hydrophobic |
| ALA 1 | NTc.Cm32 | PHE 124 | 3.32x32 | VdWContact |
| ALA 1 | NTc.Cm32 | TYR 268 | 6.51x51 | VdWContact |
| ARG 2 | NTc.Cm31 | ASP 179 | 4.60x61 | Cationic |
| ARG 2 | NTc.Cm31 | ASP 179 | 4.60x61 | HBDonor |
| ARG 2 | NTc.Cm31 | ASP 179 | 4.60x61 | VdWContact |
| ARG 2 | NTc.Cm31 | TYR 200 | - | VdWContact |
| ARG 2 | NTc.Cm31 | LEU 209 | 5.35x36 | VdWContact |
| ARG 2 | NTc.Cm31 | MET 212 | 5.38x39 | VdWContact |
| ARG 2 | NTc.Cm31 | GLU 213 | 5.39x40 | Cationic |
| ARG 2 | NTc.Cm31 | GLU 213 | 5.39x40 | VdWContact |
| ARG 2 | NTc.Cm31 | TYR 268 | 6.51x51 | HBDonor |
| ARG 2 | NTc.Cm31 | TYR 268 | 6.51x51 | VdWContact |
| THR 4 | NTc.Cm29 | HIS 121 | 3.29x29 | Hydrophobic |
| THR 4 | NTc.Cm29 | HIS 121 | 3.29x29 | VdWContact |
| THR 4 | NTc.Cm29 | LEU 183 | 4.64x65 | Hydrophobic |
| THR 4 | NTc.Cm29 | LEU 183 | 4.64x65 | VdWContact |
| THR 4 | NTc.Cm29 | CYS 196 | 45.50x50 | Hydrophobic |
| THR 4 | NTc.Cm29 | CYS 196 | 45.50x50 | VdWContact |
| THR 4 | NTc.Cm29 | ARG 197 | 45.51x51 | VdWContact |
| ASN 5 | NTc.Cm28 | LEU 209 | 5.35x36 | VdWContact |
| ASN 5 | NTc.Cm28 | GLU 213 | 5.39x40 | HBDonor |
| ASN 5 | NTc.Cm28 | GLU 213 | 5.39x40 | VdWContact |
| VAL 6 | NTc.Cm27 | TYR 195 | - | Hydrophobic |
| VAL 6 | NTc.Cm27 | ARG 197 | 45.51x51 | Hydrophobic |
| VAL 6 | NTc.Cm27 | ARG 197 | 45.51x51 | VdWContact |
| GLY 7 | NTc.Cm26 | ARG 197 | 45.51x51 | VdWContact |
| ARG 8 | NTc.Cm25 | LEU 209 | 5.35x36 | VdWContact |
| GLU 9 | NTc.Cm24 | ARG 197 | 45.51x51 | Anionic |
| GLU 9 | NTc.Cm24 | ARG 197 | 45.51x51 | HBAcceptor |
| GLU 9 | NTc.Cm24 | ARG 197 | 45.51x51 | VdWContact |
| LEU 12 | NTc.Cm21 | CYS 34 | - | Hydrophobic |
| LEU 12 | NTc.Cm21 | CYS 34 | - | VdWContact |
| LEU 12 | NTc.Cm21 | PHE 285 | - | Hydrophobic |
| LEU 12 | NTc.Cm21 | PHE 285 | - | VdWContact |
| LEU 12 | NTc.Cm21 | GLU 290 | 7.28x27 | Hydrophobic |
| GLU 13 | NTc.Cm20 | ASP 30 | - | VdWContact |
| GLU 13 | NTc.Cm20 | VAL 32 | - | Hydrophobic |
| GLU 13 | NTc.Cm20 | VAL 32 | - | VdWContact |
| TYR 14 | NTc.Cm19 | VAL 29 | - | Hydrophobic |
| TYR 14 | NTc.Cm19 | VAL 29 | - | VdWContact |
| TYR 14 | NTc.Cm19 | ASP 30 | - | Hydrophobic |
| TYR 14 | NTc.Cm19 | ASP 30 | - | VdWContact |
| TYR 14 | NTc.Cm19 | THR 31 | - | VdWContact |
| PHE 15 | NTc.Cm18 | PHE 14 | - | Hydrophobic |
| PHE 15 | NTc.Cm18 | PHE 14 | - | VdWContact |
| PHE 15 | NTc.Cm18 | VAL 29 | - | Hydrophobic |
| PHE 15 | NTc.Cm18 | VAL 29 | - | VdWContact |
| PHE 15 | NTc.Cm18 | ASP 30 | - | HBAcceptor |
| PHE 15 | NTc.Cm18 | ASP 30 | - | VdWContact |
| PHE 15 | NTc.Cm18 | THR 31 | - | Hydrophobic |
| PHE 15 | NTc.Cm18 | THR 31 | - | VdWContact |
| LYS 16 | NTc.Cm17 | ASP 30 | - | Cationic |
| LYS 16 | NTc.Cm17 | ASP 30 | - | HBDonor |
| LYS 16 | NTc.Cm17 | ASP 30 | - | VdWContact |
| LYS 16 | NTc.Cm17 | THR 31 | - | HBAcceptor |
| LYS 16 | NTc.Cm17 | THR 31 | - | HBDonor |
| LYS 16 | NTc.Cm17 | THR 31 | - | VdWContact |
| GLY 17 | NTc.Cm16 | VAL 28 | - | VdWContact |
| GLY 17 | NTc.Cm16 | VAL 29 | - | HBAcceptor |
| GLY 17 | NTc.Cm16 | VAL 29 | - | VdWContact |
| ALA 18 | NTc.Cm15 | TRP 19 | - | VdWContact |
| ALA 18 | NTc.Cm15 | CYS 21 | - | Hydrophobic |
| ALA 18 | NTc.Cm15 | CYS 21 | - | VdWContact |
| ALA 18 | NTc.Cm15 | CYS 26 | - | Hydrophobic |
| ALA 18 | NTc.Cm15 | CYS 26 | - | VdWContact |
| ALA 18 | NTc.Cm15 | ILE 27 | - | VdWContact |
| ILE 19 | NTc.Cm14 | CYS 26 | - | VdWContact |
| ILE 19 | NTc.Cm14 | ILE 27 | - | HBAcceptor |
| ILE 19 | NTc.Cm14 | ILE 27 | - | HBDonor |
| ILE 19 | NTc.Cm14 | ILE 27 | - | Hydrophobic |
| ILE 19 | NTc.Cm14 | ILE 27 | - | VdWContact |
| ILE 19 | NTc.Cm14 | VAL 29 | - | Hydrophobic |
| PRO 20 | NTc.Cm13 | TRP 19 | - | Hydrophobic |
| PRO 20 | NTc.Cm13 | TRP 19 | - | VdWContact |
| PRO 20 | NTc.Cm13 | ASP 25 | - | VdWContact |
| LEU 21 | NTc.Cm12 | ASP 25 | - | HBDonor |
| LEU 21 | NTc.Cm12 | ASP 25 | - | VdWContact |
| LEU 21 | NTc.Cm12 | ILE 27 | - | Hydrophobic |
| LYS 23 | NTc.Cm10 | PHE 6 | - | VdWContact |
| LYS 23 | NTc.Cm10 | TRP 19 | - | Hydrophobic |
| LYS 23 | NTc.Cm10 | TRP 19 | - | VdWContact |
| LEU 24 | NTc.Cm9 | ILE 27 | - | Hydrophobic |
| SER 31 | NTc.Cm2 | ILE 205 | 5.31x32 | VdWContact |
| GLU 32 | NTc.Cm1 | GLU 202 | - | VdWContact |
| GLU 32 | NTc.Cm1 | HIS 203 | - | VdWContact |
| GLU 32 | NTc.Cm1 | SER 204 | 5.30x31 | VdWContact |
| GLU 32 | NTc.Cm1 | ILE 205 | 5.31x32 | HBAcceptor |
| GLU 32 | NTc.Cm1 | ILE 205 | 5.31x32 | VdWContact |
| GLU 32 | NTc.Cm1 | LYS 206 | 5.32x33 | HBAcceptor |
| GLU 32 | NTc.Cm1 | LYS 206 | 5.32x33 | VdWContact |
| ASP 33 | CX.1 | ILE 205 | 5.31x32 | Hydrophobic |
| ASP 33 | CX.1 | ILE 205 | 5.31x32 | VdWContact |
| ASP 33 | CX.1 | LYS 206 | 5.32x33 | VdWContact |
| ASP 33 | CX.1 | LEU 209 | 5.35x36 | VdWContact |
| ASP 33 | CX.1 | ILE 279 | 6.62x62 | VdWContact |
| CYS 34 | CX.5 | LYS 206 | 5.32x33 | HBAcceptor |
| CYS 34 | CX.5 | LYS 206 | 5.32x33 | VdWContact |
| SER 35 | cxb1.1 | HIS 281 | 6.64x64 | VdWContact |
| PHE 41 | cxb1.10 | ILE 27 | - | Hydrophobic |
| PHE 41 | cxb1.10 | ILE 27 | - | VdWContact |
| GLN 45 | cxb1.16 | PHE 6 | - | Hydrophobic |
| GLN 45 | cxb1.16 | PHE 6 | - | VdWContact |
| GLN 45 | cxb1.16 | TYR 8 | - | Hydrophobic |
| GLN 45 | cxb1.16 | TYR 8 | - | VdWContact |
| GLY 46 | B1.1 | SER 190 | - | VdWContact |
| ARG 47 | B1.2 | TYR 8 | - | VdWContact |
| ARG 47 | B1.2 | PHE 14 | - | Hydrophobic |
| ILE 49 | B1.4 | PHE 14 | - | Hydrophobic |
| ILE 49 | B1.4 | PHE 14 | - | VdWContact |
| SER 51 | B1.6 | VAL 29 | - | VdWContact |
| ASP 52 | B1.7 | VAL 29 | - | Hydrophobic |
| ASP 52 | B1.7 | VAL 29 | - | VdWContact |
| ASN 55 | b1b2.9 | VAL 28 | - | HBDonor |
| ASN 55 | b1b2.9 | VAL 28 | - | VdWContact |
| ARG 57 | b1b2.12 | CYS 21 | - | Cationic |
| ARG 57 | b1b2.12 | CYS 26 | - | HBDonor |
| ARG 57 | b1b2.12 | CYS 26 | - | VdWContact |
| ARG 57 | b1b2.12 | ILE 27 | - | Hydrophobic |
| ARG 57 | b1b2.12 | ILE 27 | - | VdWContact |
| ARG 57 | b1b2.12 | VAL 28 | - | VdWContact |
| VAL 58 | b1b2.13 | VAL 29 | - | Hydrophobic |
| ALA 61 | B2.1 | ILE 27 | - | Hydrophobic |
| ALA 61 | B2.1 | ILE 27 | - | VdWContact |
