Predicted complex interactions
CXCL13_HUMAN + CXCR6
SUMMARY
- Chemokine
- CXCL13_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR6 View partner entry
- Partner description
- UniProt: O00574; Gene: cxcr6_human; Family: Chemokine
- Interactions detected
- 104
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm32 | TRP 87 | 2.60x60 | CationPi |
| VAL 1 | NTc.Cm32 | TRP 87 | 2.60x60 | Hydrophobic |
| VAL 1 | NTc.Cm32 | TRP 87 | 2.60x60 | VdWContact |
| VAL 1 | NTc.Cm32 | LEU 106 | 3.29x29 | Hydrophobic |
| VAL 1 | NTc.Cm32 | LEU 106 | 3.29x29 | VdWContact |
| VAL 1 | NTc.Cm32 | TYR 109 | 3.32x32 | Hydrophobic |
| VAL 1 | NTc.Cm32 | TYR 109 | 3.32x32 | VdWContact |
| VAL 1 | NTc.Cm32 | GLU 274 | 7.39x38 | Cationic |
| VAL 1 | NTc.Cm32 | GLU 274 | 7.39x38 | VdWContact |
| VAL 1 | NTc.Cm32 | TYR 278 | 7.43x42 | HBDonor |
| VAL 1 | NTc.Cm32 | TYR 278 | 7.43x42 | VdWContact |
| LEU 2 | NTc.Cm31 | LEU 34 | 1.35x35 | Hydrophobic |
| LEU 2 | NTc.Cm31 | TYR 38 | 1.39x39 | Hydrophobic |
| LEU 2 | NTc.Cm31 | TYR 38 | 1.39x39 | VdWContact |
| LEU 2 | NTc.Cm31 | TRP 87 | 2.60x60 | Hydrophobic |
| GLU 3 | NTc.Cm30 | PHE 247 | 6.51x51 | Hydrophobic |
| GLU 3 | NTc.Cm30 | LYS 251 | 6.55x55 | Anionic |
| GLU 3 | NTc.Cm30 | LYS 251 | 6.55x55 | HBAcceptor |
| GLU 3 | NTc.Cm30 | LYS 251 | 6.55x55 | Hydrophobic |
| GLU 3 | NTc.Cm30 | LYS 251 | 6.55x55 | VdWContact |
| GLU 3 | NTc.Cm30 | ARG 254 | 6.58x58 | Anionic |
| GLU 3 | NTc.Cm30 | ARG 254 | 6.58x58 | HBAcceptor |
| GLU 3 | NTc.Cm30 | ARG 254 | 6.58x58 | VdWContact |
| GLU 3 | NTc.Cm30 | ILE 270 | 7.35x34 | Hydrophobic |
| GLU 3 | NTc.Cm30 | GLU 274 | 7.39x38 | HBDonor |
| GLU 3 | NTc.Cm30 | GLU 274 | 7.39x38 | VdWContact |
| VAL 4 | NTc.Cm29 | PHE 26 | 1.27x27 | Hydrophobic |
| VAL 4 | NTc.Cm29 | HIS 267 | 7.32x31 | Hydrophobic |
| VAL 4 | NTc.Cm29 | ILE 270 | 7.35x34 | Hydrophobic |
| TYR 5 | NTc.Cm28 | ILE 179 | - | Hydrophobic |
| TYR 5 | NTc.Cm28 | ILE 179 | - | VdWContact |
| TYR 5 | NTc.Cm28 | GLY 181 | 45.51x51 | VdWContact |
| TYR 5 | NTc.Cm28 | TYR 182 | 45.52x52 | HBAcceptor |
| TYR 5 | NTc.Cm28 | TYR 182 | 45.52x52 | HBDonor |
| TYR 5 | NTc.Cm28 | TYR 182 | 45.52x52 | VdWContact |
| TYR 6 | NTc.Cm27 | PHE 26 | 1.27x27 | Hydrophobic |
| TYR 6 | NTc.Cm27 | PHE 26 | 1.27x27 | VdWContact |
| TYR 6 | NTc.Cm27 | LEU 27 | 1.28x28 | Hydrophobic |
| TYR 6 | NTc.Cm27 | LEU 27 | 1.28x28 | VdWContact |
| TYR 6 | NTc.Cm27 | SER 30 | 1.31x31 | VdWContact |
| TYR 6 | NTc.Cm27 | LEU 34 | 1.35x35 | Hydrophobic |
| TYR 6 | NTc.Cm27 | LEU 34 | 1.35x35 | VdWContact |
| TYR 6 | NTc.Cm27 | LYS 177 | - | HBAcceptor |
| TYR 6 | NTc.Cm27 | LYS 177 | - | VdWContact |
| TYR 6 | NTc.Cm27 | MET 271 | 7.36x35 | Hydrophobic |
| THR 7 | NTc.Cm26 | HIS 23 | - | HBAcceptor |
| THR 7 | NTc.Cm26 | HIS 23 | - | VdWContact |
| THR 7 | NTc.Cm26 | LEU 27 | 1.28x28 | VdWContact |
| THR 7 | NTc.Cm26 | LEU 175 | - | Hydrophobic |
| THR 7 | NTc.Cm26 | ASP 176 | - | VdWContact |
| THR 7 | NTc.Cm26 | LYS 177 | - | Hydrophobic |
| THR 7 | NTc.Cm26 | ILE 179 | - | Hydrophobic |
| SER 8 | NTc.Cm25 | ASP 176 | - | HBDonor |
| SER 8 | NTc.Cm25 | ASP 176 | - | VdWContact |
| LEU 9 | NTc.Cm24 | LEU 175 | - | Hydrophobic |
| LEU 9 | NTc.Cm24 | LEU 175 | - | VdWContact |
| LEU 9 | NTc.Cm24 | ASP 176 | - | Hydrophobic |
| ARG 10 | NTc.Cm23 | SER 19 | - | HBDonor |
| ARG 10 | NTc.Cm23 | SER 19 | - | VdWContact |
| ARG 10 | NTc.Cm23 | HIS 23 | - | Hydrophobic |
| ARG 10 | NTc.Cm23 | HIS 23 | - | VdWContact |
| ARG 10 | NTc.Cm23 | THR 264 | 7.29x28 | HBDonor |
| ARG 10 | NTc.Cm23 | THR 264 | 7.29x28 | VdWContact |
| CYS 11 | NTc.Cm22 | TYR 261 | 7.26x25 | Hydrophobic |
| CYS 11 | NTc.Cm22 | TYR 261 | 7.26x25 | VdWContact |
| CYS 11 | NTc.Cm22 | ALA 262 | 7.27x26 | Hydrophobic |
| CYS 11 | NTc.Cm22 | ALA 262 | 7.27x26 | VdWContact |
| ARG 12 | NTc.Cm21 | PHE 15 | - | Hydrophobic |
| ARG 12 | NTc.Cm21 | PHE 15 | - | VdWContact |
| ARG 12 | NTc.Cm21 | ASN 16 | - | HBAcceptor |
| ARG 12 | NTc.Cm21 | ASN 16 | - | VdWContact |
| CYS 13 | NTc.Cm20 | SER 14 | - | VdWContact |
| CYS 13 | NTc.Cm20 | TRP 258 | - | Hydrophobic |
| CYS 13 | NTc.Cm20 | TRP 258 | - | VdWContact |
| VAL 14 | NTc.Cm19 | SER 14 | - | HBDonor |
| VAL 14 | NTc.Cm19 | SER 14 | - | VdWContact |
| VAL 14 | NTc.Cm19 | ASN 16 | - | Hydrophobic |
| VAL 14 | NTc.Cm19 | GLU 259 | 7.24x23 | VdWContact |
| VAL 14 | NTc.Cm19 | ALA 262 | 7.27x26 | Hydrophobic |
| GLN 15 | NTc.Cm18 | SER 14 | - | VdWContact |
| GLU 16 | NTc.Cm17 | TRP 258 | - | Hydrophobic |
| GLU 16 | NTc.Cm17 | TRP 258 | - | VdWContact |
| ARG 24 | NTc.Cm9 | TYR 6 | - | VdWContact |
| PHE 25 | NTc.Cm8 | TYR 6 | - | Hydrophobic |
| ARG 34 | CX.4 | HIS 183 | - | Hydrophobic |
| ARG 34 | CX.4 | HIS 183 | - | VdWContact |
| ARG 34 | CX.4 | GLU 185 | 5.32x33 | Cationic |
| ARG 34 | CX.4 | GLU 185 | 5.32x33 | HBDonor |
| ARG 34 | CX.4 | GLU 185 | 5.32x33 | VdWContact |
| GLY 35 | CX.5 | LEU 175 | - | VdWContact |
| GLY 35 | CX.5 | HIS 183 | - | VdWContact |
| PRO 39 | cxb1.6 | GLU 185 | 5.32x33 | Hydrophobic |
| PRO 39 | cxb1.6 | TYR 261 | 7.26x25 | Hydrophobic |
| PRO 39 | cxb1.6 | TYR 261 | 7.26x25 | VdWContact |
| ARG 40 | cxb1.7 | GLU 185 | 5.32x33 | Cationic |
| ARG 40 | cxb1.7 | TRP 258 | - | VdWContact |
| ILE 44 | cxb1.14 | PHE 15 | - | Hydrophobic |
| ILE 44 | cxb1.14 | PHE 15 | - | VdWContact |
| SER 51 | B1.5 | GLY 11 | - | VdWContact |
| ILE 52 | B1.6 | SER 13 | - | VdWContact |
| ILE 52 | B1.6 | SER 14 | - | HBAcceptor |
| ILE 52 | B1.6 | PHE 15 | - | Hydrophobic |
| CYS 54 | b1b2.4 | SER 14 | - | HBDonor |
| CYS 54 | b1b2.4 | SER 14 | - | VdWContact |
