Predicted complex interactions
CXCL14_HUMAN + CXCR6
SUMMARY
- Chemokine
- CXCL14_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR6 View partner entry
- Partner description
- UniProt: O00574; Gene: cxcr6_human; Family: Chemokine
- Interactions detected
- 128
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ARG 13 | NTc.Cm24 | ASP 176 | - | VdWContact |
| TYR 14 | NTc.Cm23 | LEU 175 | - | Hydrophobic |
| TYR 14 | NTc.Cm23 | LEU 175 | - | VdWContact |
| TYR 14 | NTc.Cm23 | ASP 176 | - | HBDonor |
| TYR 14 | NTc.Cm23 | ASP 176 | - | VdWContact |
| SER 15 | NTc.Cm22 | ASP 176 | - | HBDonor |
| SER 15 | NTc.Cm22 | ASP 176 | - | VdWContact |
| LYS 18 | NTc.Cm19 | GLN 20 | - | HBDonor |
| LYS 18 | NTc.Cm19 | GLN 20 | - | VdWContact |
| LYS 19 | NTc.Cm18 | ASN 16 | - | HBDonor |
| LYS 19 | NTc.Cm18 | ASN 16 | - | VdWContact |
| LYS 19 | NTc.Cm18 | SER 19 | - | HBDonor |
| LYS 19 | NTc.Cm18 | SER 19 | - | VdWContact |
| LYS 19 | NTc.Cm18 | GLN 20 | - | Hydrophobic |
| LYS 19 | NTc.Cm18 | GLN 20 | - | VdWContact |
| LEU 20 | NTc.Cm17 | ALA 262 | 7.27x26 | Hydrophobic |
| GLU 21 | NTc.Cm16 | SER 19 | - | HBAcceptor |
| GLU 21 | NTc.Cm16 | SER 19 | - | VdWContact |
| MET 22 | NTc.Cm15 | TRP 258 | - | Hydrophobic |
| MET 22 | NTc.Cm15 | TRP 258 | - | VdWContact |
| MET 22 | NTc.Cm15 | GLU 259 | 7.24x23 | Hydrophobic |
| MET 22 | NTc.Cm15 | GLU 259 | 7.24x23 | VdWContact |
| MET 22 | NTc.Cm15 | ALA 262 | 7.27x26 | Hydrophobic |
| MET 22 | NTc.Cm15 | ALA 262 | 7.27x26 | VdWContact |
| LYS 23 | NTc.Cm14 | ASN 16 | - | HBDonor |
| LYS 23 | NTc.Cm14 | ASN 16 | - | VdWContact |
| PRO 27 | NTc.Cm10 | PHE 12 | - | Hydrophobic |
| PRO 27 | NTc.Cm10 | PHE 12 | - | VdWContact |
| VAL 34 | NTc.Cm3 | TRP 258 | - | Hydrophobic |
| PRO 53 | B1.4 | TRP 258 | - | Hydrophobic |
| PRO 53 | B1.4 | TRP 258 | - | VdWContact |
| GLN 56 | B1.7 | GLU 185 | 5.32x33 | VdWContact |
| LYS 59 | b1b2.7 | TRP 258 | - | Hydrophobic |
| LYS 59 | b1b2.7 | TRP 258 | - | VdWContact |
| ARG 60 | b1b2.8 | ASP 184 | 5.31x32 | Cationic |
| ARG 60 | b1b2.8 | ASP 184 | 5.31x32 | Hydrophobic |
| ARG 60 | b1b2.8 | ASP 184 | 5.31x32 | VdWContact |
| ILE 62 | b1b2.10 | TRP 258 | - | Hydrophobic |
| ILE 62 | b1b2.10 | TRP 258 | - | VdWContact |
| ILE 62 | b1b2.10 | TYR 261 | 7.26x25 | Hydrophobic |
| ILE 62 | b1b2.10 | TYR 261 | 7.26x25 | VdWContact |
| LYS 63 | b1b2.12 | TYR 261 | 7.26x25 | Hydrophobic |
| LYS 63 | b1b2.12 | TYR 261 | 7.26x25 | VdWContact |
| TRP 64 | b1b2.13 | PHE 173 | - | Hydrophobic |
| TRP 64 | b1b2.13 | PHE 173 | - | VdWContact |
| TRP 64 | b1b2.13 | LEU 175 | - | Hydrophobic |
| TRP 64 | b1b2.13 | LEU 175 | - | VdWContact |
| TRP 64 | b1b2.13 | HIS 183 | - | Hydrophobic |
| TRP 64 | b1b2.13 | HIS 183 | - | VdWContact |
| TRP 64 | b1b2.13 | ASP 184 | 5.31x32 | HBDonor |
| TRP 64 | b1b2.13 | ASP 184 | 5.31x32 | VdWContact |
| TYR 65 | b1b2.14 | HIS 23 | - | HBAcceptor |
| TYR 65 | b1b2.14 | HIS 23 | - | VdWContact |
| ASN 66 | b1b2.16 | TYR 261 | 7.26x25 | HBDonor |
| ASN 66 | b1b2.16 | TYR 261 | 7.26x25 | Hydrophobic |
| ASN 66 | b1b2.16 | TYR 261 | 7.26x25 | VdWContact |
| ASN 66 | b1b2.16 | HIS 267 | 7.32x31 | Hydrophobic |
| TRP 68 | B2.1 | LEU 175 | - | Hydrophobic |
| TRP 68 | B2.1 | LEU 175 | - | VdWContact |
| TRP 68 | B2.1 | LYS 177 | - | HBAcceptor |
| TRP 68 | B2.1 | LYS 177 | - | Hydrophobic |
| TRP 68 | B2.1 | LYS 177 | - | PiCation |
| TRP 68 | B2.1 | LYS 177 | - | VdWContact |
| TRP 68 | B2.1 | ILE 179 | - | Hydrophobic |
| TRP 68 | B2.1 | ILE 179 | - | VdWContact |
| ASN 69 | B2.2 | HIS 23 | - | VdWContact |
| ASN 69 | B2.2 | LEU 27 | 1.28x28 | Hydrophobic |
| GLU 70 | B2.3 | ARG 254 | 6.58x58 | Anionic |
| GLU 70 | B2.3 | ARG 254 | 6.58x58 | HBAcceptor |
| GLU 70 | B2.3 | ARG 254 | 6.58x58 | VdWContact |
| GLU 70 | B2.3 | HIS 267 | 7.32x31 | HBAcceptor |
| GLU 70 | B2.3 | HIS 267 | 7.32x31 | Hydrophobic |
| GLU 70 | B2.3 | HIS 267 | 7.32x31 | VdWContact |
| LYS 71 | B2.4 | ILE 179 | - | Hydrophobic |
| LYS 71 | B2.4 | ILE 179 | - | VdWContact |
| LYS 71 | B2.4 | CYS 180 | 45.50x50 | HBDonor |
| LYS 71 | B2.4 | CYS 180 | 45.50x50 | VdWContact |
| LYS 71 | B2.4 | GLY 181 | 45.51x51 | VdWContact |
| LYS 71 | B2.4 | TYR 182 | 45.52x52 | VdWContact |
| ARG 72 | B2.5 | LYS 31 | 1.32x32 | VdWContact |
| ARG 72 | B2.5 | ALA 90 | 2.63x63 | VdWContact |
| ARG 72 | B2.5 | GLY 91 | 2.64x64 | VdWContact |
| ARG 72 | B2.5 | ILE 92 | 2.65x65 | HBDonor |
| ARG 72 | B2.5 | ILE 92 | 2.65x65 | VdWContact |
| ARG 72 | B2.5 | LYS 177 | - | VdWContact |
| ARG 73 | B2.6 | LEU 34 | 1.35x35 | HBDonor |
| ARG 73 | B2.6 | LEU 34 | 1.35x35 | Hydrophobic |
| ARG 73 | B2.6 | LEU 34 | 1.35x35 | VdWContact |
| ARG 73 | B2.6 | MET 37 | 1.38x38 | VdWContact |
| ARG 73 | B2.6 | TYR 38 | 1.39x39 | Hydrophobic |
| ARG 73 | B2.6 | TYR 38 | 1.39x39 | VdWContact |
| ARG 73 | B2.6 | MET 271 | 7.36x35 | HBDonor |
| ARG 73 | B2.6 | MET 271 | 7.36x35 | VdWContact |
| ARG 73 | B2.6 | GLU 274 | 7.39x38 | Cationic |
| ARG 73 | B2.6 | GLU 274 | 7.39x38 | HBDonor |
| ARG 73 | B2.6 | GLU 274 | 7.39x38 | VdWContact |
| VAL 74 | b2b3.2 | TRP 87 | 2.60x60 | Hydrophobic |
| VAL 74 | b2b3.2 | TRP 87 | 2.60x60 | VdWContact |
| VAL 74 | b2b3.2 | LEU 106 | 3.29x29 | Hydrophobic |
| VAL 74 | b2b3.2 | LEU 106 | 3.29x29 | VdWContact |
| VAL 74 | b2b3.2 | ILE 179 | - | Hydrophobic |
| VAL 74 | b2b3.2 | CYS 180 | 45.50x50 | Hydrophobic |
| VAL 74 | b2b3.2 | CYS 180 | 45.50x50 | VdWContact |
| TYR 75 | b2b3.3 | TYR 109 | 3.32x32 | Hydrophobic |
| TYR 75 | b2b3.3 | TYR 109 | 3.32x32 | VdWContact |
| TYR 75 | b2b3.3 | PHE 247 | 6.51x51 | Hydrophobic |
| TYR 75 | b2b3.3 | PHE 247 | 6.51x51 | PiStacking |
| TYR 75 | b2b3.3 | PHE 247 | 6.51x51 | VdWContact |
| TYR 75 | b2b3.3 | LYS 251 | 6.55x55 | Hydrophobic |
| TYR 75 | b2b3.3 | LYS 251 | 6.55x55 | VdWContact |
| TYR 75 | b2b3.3 | ARG 254 | 6.58x58 | HBAcceptor |
| TYR 75 | b2b3.3 | ARG 254 | 6.58x58 | VdWContact |
| TYR 75 | b2b3.3 | GLU 274 | 7.39x38 | Hydrophobic |
| TYR 75 | b2b3.3 | GLU 274 | 7.39x38 | VdWContact |
| TYR 75 | b2b3.3 | TYR 278 | 7.43x42 | HBDonor |
| TYR 75 | b2b3.3 | TYR 278 | 7.43x42 | Hydrophobic |
| TYR 75 | b2b3.3 | TYR 278 | 7.43x42 | VdWContact |
| GLU 76 | b2b3.4 | PHE 173 | - | VdWContact |
| GLU 76 | b2b3.4 | GLY 181 | 45.51x51 | VdWContact |
| GLU 76 | b2b3.4 | TYR 182 | 45.52x52 | Hydrophobic |
| GLU 76 | b2b3.4 | TYR 182 | 45.52x52 | VdWContact |
| GLU 76 | b2b3.4 | ARG 254 | 6.58x58 | HBAcceptor |
| GLU 76 | b2b3.4 | ARG 254 | 6.58x58 | VdWContact |
| GLU 77 | b2b3.5 | ASP 184 | 5.31x32 | Hydrophobic |
| GLU 77 | b2b3.5 | ASP 184 | 5.31x32 | VdWContact |
| GLU 77 | b2b3.5 | GLU 185 | 5.32x33 | HBAcceptor |
| GLU 77 | b2b3.5 | GLU 185 | 5.32x33 | VdWContact |
| GLU 77 | b2b3.5 | TYR 261 | 7.26x25 | VdWContact |
