Predicted complex interactions
CXCL16_HUMAN + CXCR6
SUMMARY
- Chemokine
- CXCL16_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR6 View partner entry
- Partner description
- UniProt: O00574; Gene: cxcr6_human; Family: Chemokine
- Interactions detected
- 102
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ASN 1 | NTc.Cm56 | TYR 38 | 1.39x39 | HBDonor |
| ASN 1 | NTc.Cm56 | TYR 38 | 1.39x39 | VdWContact |
| ASN 1 | NTc.Cm56 | TRP 87 | 2.60x60 | Hydrophobic |
| ASN 1 | NTc.Cm56 | TRP 87 | 2.60x60 | VdWContact |
| ASN 1 | NTc.Cm56 | GLU 274 | 7.39x38 | HBDonor |
| ASN 1 | NTc.Cm56 | GLU 274 | 7.39x38 | VdWContact |
| ASN 1 | NTc.Cm56 | TYR 278 | 7.43x42 | VdWContact |
| GLU 2 | NTc.Cm55 | PHE 247 | 6.51x51 | Hydrophobic |
| GLU 2 | NTc.Cm55 | LYS 251 | 6.55x55 | Anionic |
| GLU 2 | NTc.Cm55 | LYS 251 | 6.55x55 | Hydrophobic |
| GLU 2 | NTc.Cm55 | LYS 251 | 6.55x55 | VdWContact |
| GLU 2 | NTc.Cm55 | ARG 254 | 6.58x58 | Anionic |
| GLU 2 | NTc.Cm55 | ARG 254 | 6.58x58 | HBAcceptor |
| GLU 2 | NTc.Cm55 | ARG 254 | 6.58x58 | VdWContact |
| GLU 2 | NTc.Cm55 | ILE 270 | 7.35x34 | Hydrophobic |
| GLU 2 | NTc.Cm55 | GLU 274 | 7.39x38 | HBDonor |
| GLU 2 | NTc.Cm55 | GLU 274 | 7.39x38 | VdWContact |
| GLY 3 | NTc.Cm54 | LEU 34 | 1.35x35 | VdWContact |
| GLY 3 | NTc.Cm54 | GLU 274 | 7.39x38 | HBDonor |
| GLY 3 | NTc.Cm54 | GLU 274 | 7.39x38 | VdWContact |
| VAL 5 | NTc.Cm52 | ILE 179 | - | Hydrophobic |
| THR 6 | NTc.Cm51 | PHE 26 | 1.27x27 | Hydrophobic |
| THR 6 | NTc.Cm51 | PHE 26 | 1.27x27 | VdWContact |
| THR 6 | NTc.Cm51 | HIS 267 | 7.32x31 | Hydrophobic |
| THR 6 | NTc.Cm51 | HIS 267 | 7.32x31 | VdWContact |
| THR 6 | NTc.Cm51 | ILE 270 | 7.35x34 | Hydrophobic |
| GLY 7 | NTc.Cm50 | HIS 23 | - | VdWContact |
| GLY 7 | NTc.Cm50 | LEU 27 | 1.28x28 | VdWContact |
| GLY 7 | NTc.Cm50 | HIS 267 | 7.32x31 | VdWContact |
| TYR 10 | NTc.Cm47 | ASN 16 | - | VdWContact |
| TYR 10 | NTc.Cm47 | SER 19 | - | HBAcceptor |
| TYR 10 | NTc.Cm47 | SER 19 | - | VdWContact |
| TYR 10 | NTc.Cm47 | GLN 20 | - | Hydrophobic |
| TYR 10 | NTc.Cm47 | GLN 20 | - | VdWContact |
| TYR 10 | NTc.Cm47 | HIS 23 | - | Hydrophobic |
| TYR 10 | NTc.Cm47 | HIS 23 | - | VdWContact |
| CYS 11 | NTc.Cm46 | ALA 262 | 7.27x26 | Hydrophobic |
| CYS 11 | NTc.Cm46 | ALA 262 | 7.27x26 | VdWContact |
| GLY 12 | NTc.Cm45 | ASN 16 | - | VdWContact |
| LYS 13 | NTc.Cm44 | PHE 12 | - | Hydrophobic |
| LYS 13 | NTc.Cm44 | PHE 12 | - | VdWContact |
| ARG 14 | NTc.Cm43 | TRP 258 | - | Hydrophobic |
| ARG 14 | NTc.Cm43 | ALA 262 | 7.27x26 | HBDonor |
| ARG 14 | NTc.Cm43 | ALA 262 | 7.27x26 | Hydrophobic |
| ARG 14 | NTc.Cm43 | ALA 262 | 7.27x26 | VdWContact |
| ILE 15 | NTc.Cm42 | TRP 258 | - | VdWContact |
| SER 16 | NTc.Cm41 | GLU 259 | 7.24x23 | HBDonor |
| SER 16 | NTc.Cm41 | GLU 259 | 7.24x23 | VdWContact |
| SER 17 | NTc.Cm40 | TRP 258 | - | HBAcceptor |
| SER 17 | NTc.Cm40 | TRP 258 | - | VdWContact |
| SER 17 | NTc.Cm40 | GLU 259 | 7.24x23 | HBDonor |
| SER 17 | NTc.Cm40 | GLU 259 | 7.24x23 | VdWContact |
| PHE 25 | NTc.Cm32 | PHE 12 | - | Hydrophobic |
| ARG 28 | NTc.Cm29 | ASP 5 | - | Cationic |
| ARG 28 | NTc.Cm29 | ASP 5 | - | HBDonor |
| ARG 28 | NTc.Cm29 | ASP 5 | - | VdWContact |
| ARG 28 | NTc.Cm29 | GLU 8 | - | Cationic |
| ARG 28 | NTc.Cm29 | GLU 8 | - | VdWContact |
| ARG 28 | NTc.Cm29 | ASP 9 | - | Cationic |
| ARG 28 | NTc.Cm29 | ASP 9 | - | HBDonor |
| ARG 28 | NTc.Cm29 | ASP 9 | - | VdWContact |
| HIS 37 | NTc.Cm20 | ASP 176 | - | HBDonor |
| HIS 37 | NTc.Cm20 | ASP 176 | - | VdWContact |
| ARG 38 | NTc.Cm19 | LEU 175 | - | VdWContact |
| ARG 38 | NTc.Cm19 | ASP 184 | 5.31x32 | Cationic |
| ARG 38 | NTc.Cm19 | ASP 184 | 5.31x32 | HBDonor |
| ARG 38 | NTc.Cm19 | ASP 184 | 5.31x32 | VdWContact |
| CYS 39 | NTc.Cm18 | LEU 175 | - | VdWContact |
| LEU 40 | NTc.Cm17 | PHE 173 | - | Hydrophobic |
| LEU 40 | NTc.Cm17 | PHE 173 | - | VdWContact |
| LEU 40 | NTc.Cm17 | LEU 175 | - | Hydrophobic |
| LEU 40 | NTc.Cm17 | ILE 179 | - | Hydrophobic |
| LEU 40 | NTc.Cm17 | ASP 184 | 5.31x32 | VdWContact |
| TYR 41 | NTc.Cm16 | ASP 184 | 5.31x32 | VdWContact |
| TYR 41 | NTc.Cm16 | TRP 258 | - | Hydrophobic |
| TYR 41 | NTc.Cm16 | TYR 261 | 7.26x25 | Hydrophobic |
| TYR 41 | NTc.Cm16 | TYR 261 | 7.26x25 | PiStacking |
| TYR 41 | NTc.Cm16 | TYR 261 | 7.26x25 | VdWContact |
| TYR 42 | NTc.Cm15 | TRP 258 | - | Hydrophobic |
| TYR 42 | NTc.Cm15 | TRP 258 | - | VdWContact |
| TYR 42 | NTc.Cm15 | TYR 261 | 7.26x25 | Hydrophobic |
| TYR 42 | NTc.Cm15 | TYR 261 | 7.26x25 | VdWContact |
| TYR 42 | NTc.Cm15 | ALA 262 | 7.27x26 | Hydrophobic |
| TYR 42 | NTc.Cm15 | ALA 262 | 7.27x26 | VdWContact |
| ARG 44 | NTc.Cm13 | ASP 176 | - | Cationic |
| ARG 44 | NTc.Cm13 | ASP 176 | - | HBDonor |
| ARG 44 | NTc.Cm13 | ASP 176 | - | VdWContact |
| TRP 50 | NTc.Cm7 | ASP 9 | - | HBDonor |
| TRP 50 | NTc.Cm7 | ASP 9 | - | VdWContact |
| TRP 50 | NTc.Cm7 | PHE 12 | - | Hydrophobic |
| TRP 50 | NTc.Cm7 | ASN 16 | - | VdWContact |
| SER 51 | NTc.Cm6 | ASN 16 | - | HBAcceptor |
| SER 51 | NTc.Cm6 | ASN 16 | - | VdWContact |
| CYS 53 | NTc.Cm4 | TRP 258 | - | Hydrophobic |
| CYS 53 | NTc.Cm4 | TRP 258 | - | VdWContact |
| GLY 54 | NTc.Cm3 | TRP 258 | - | VdWContact |
| GLY 55 | NTc.Cm2 | TRP 258 | - | VdWContact |
| ASN 56 | NTc.Cm1 | ASP 184 | 5.31x32 | HBDonor |
| ASN 56 | NTc.Cm1 | ASP 184 | 5.31x32 | VdWContact |
| LYS 57 | CX.1 | GLU 185 | 5.32x33 | Cationic |
| LYS 57 | CX.1 | GLU 185 | 5.32x33 | HBDonor |
| LYS 57 | CX.1 | GLU 185 | 5.32x33 | VdWContact |
