Predicted complex interactions
CXCL17_HUMAN + CXCR6
SUMMARY
- Chemokine
- CXCL17_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR6 View partner entry
- Partner description
- UniProt: O00574; Gene: cxcr6_human; Family: Chemokine
- Interactions detected
- 106
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LYS 32 | NTc.Cm18 | LEU 27 | 1.28x28 | Hydrophobic |
| LYS 32 | NTc.Cm18 | ASP 176 | - | Cationic |
| TRP 34 | NTc.Cm16 | TYR 261 | 7.26x25 | Hydrophobic |
| TRP 34 | NTc.Cm16 | TYR 261 | 7.26x25 | VdWContact |
| TRP 34 | NTc.Cm16 | ALA 262 | 7.27x26 | Hydrophobic |
| TRP 34 | NTc.Cm16 | ALA 262 | 7.27x26 | VdWContact |
| PHE 35 | NTc.Cm15 | HIS 23 | - | Hydrophobic |
| PHE 35 | NTc.Cm15 | HIS 23 | - | VdWContact |
| PHE 35 | NTc.Cm15 | LEU 27 | 1.28x28 | Hydrophobic |
| PHE 35 | NTc.Cm15 | HIS 267 | 7.32x31 | Hydrophobic |
| PHE 35 | NTc.Cm15 | HIS 267 | 7.32x31 | PiStacking |
| PHE 35 | NTc.Cm15 | HIS 267 | 7.32x31 | VdWContact |
| LEU 36 | NTc.Cm14 | GLN 20 | - | VdWContact |
| LEU 36 | NTc.Cm14 | GLN 24 | 1.25x25 | Hydrophobic |
| LEU 36 | NTc.Cm14 | GLN 24 | 1.25x25 | VdWContact |
| LEU 36 | NTc.Cm14 | LEU 27 | 1.28x28 | Hydrophobic |
| ALA 38 | NTc.Cm12 | SER 19 | - | VdWContact |
| ALA 38 | NTc.Cm12 | GLN 20 | - | HBAcceptor |
| ALA 38 | NTc.Cm12 | GLN 20 | - | Hydrophobic |
| ALA 38 | NTc.Cm12 | GLN 20 | - | VdWContact |
| ALA 38 | NTc.Cm12 | HIS 23 | - | Hydrophobic |
| PRO 39 | NTc.Cm11 | ASN 16 | - | Hydrophobic |
| PRO 39 | NTc.Cm11 | ASN 16 | - | VdWContact |
| ARG 40 | NTc.Cm10 | GLN 20 | - | Hydrophobic |
| ARG 40 | NTc.Cm10 | GLN 20 | - | VdWContact |
| ARG 40 | NTc.Cm10 | GLU 21 | - | Cationic |
| ARG 40 | NTc.Cm10 | GLN 24 | 1.25x25 | HBDonor |
| ARG 40 | NTc.Cm10 | GLN 24 | 1.25x25 | VdWContact |
| ARG 41 | NTc.Cm9 | ASP 17 | - | Cationic |
| ARG 41 | NTc.Cm9 | ASP 17 | - | HBDonor |
| ARG 41 | NTc.Cm9 | ASP 17 | - | VdWContact |
| PHE 59 | cxb1.11 | TRP 258 | - | Hydrophobic |
| PHE 59 | cxb1.11 | TRP 258 | - | VdWContact |
| PHE 59 | cxb1.11 | GLU 259 | 7.24x23 | Hydrophobic |
| PHE 59 | cxb1.11 | GLU 259 | 7.24x23 | VdWContact |
| LYS 60 | cxb1.14 | ALA 262 | 7.27x26 | Hydrophobic |
| LYS 60 | cxb1.14 | ALA 262 | 7.27x26 | VdWContact |
| LYS 65 | B1.4 | GLU 8 | - | Cationic |
| LYS 65 | B1.4 | GLU 8 | - | HBDonor |
| LYS 65 | B1.4 | GLU 8 | - | VdWContact |
| SER 79 | b1b2.14 | TRP 258 | - | VdWContact |
| ARG 80 | b1b2.16 | GLU 185 | 5.32x33 | Cationic |
| ARG 80 | b1b2.16 | GLU 185 | 5.32x33 | VdWContact |
| CYS 82 | b1b2.18 | TRP 258 | - | Hydrophobic |
| CYS 82 | b1b2.18 | TRP 258 | - | VdWContact |
| GLN 83 | b1b2.19 | TRP 258 | - | Hydrophobic |
| GLN 83 | b1b2.19 | TRP 258 | - | VdWContact |
| GLN 84 | b1b2.20 | ASP 184 | 5.31x32 | Hydrophobic |
| GLN 84 | b1b2.20 | ASP 184 | 5.31x32 | VdWContact |
| LYS 87 | b1b2.23 | ASP 184 | 5.31x32 | HBDonor |
| LYS 87 | b1b2.23 | ASP 184 | 5.31x32 | Hydrophobic |
| LYS 87 | b1b2.23 | ASP 184 | 5.31x32 | VdWContact |
| LYS 87 | b1b2.23 | TYR 261 | 7.26x25 | Hydrophobic |
| LYS 87 | b1b2.23 | TYR 261 | 7.26x25 | VdWContact |
| GLN 88 | b1b2.24 | LEU 175 | - | Hydrophobic |
| GLN 90 | B2.1 | ARG 254 | 6.58x58 | VdWContact |
| GLN 90 | B2.1 | TYR 261 | 7.26x25 | Hydrophobic |
| GLN 90 | B2.1 | TYR 261 | 7.26x25 | VdWContact |
| GLN 90 | B2.1 | HIS 267 | 7.32x31 | Hydrophobic |
| GLN 90 | B2.1 | HIS 267 | 7.32x31 | VdWContact |
| GLN 90 | B2.1 | ILE 270 | 7.35x34 | VdWContact |
| LEU 91 | B2.2 | PHE 173 | - | Hydrophobic |
| LEU 91 | B2.2 | ILE 179 | - | VdWContact |
| LEU 91 | B2.2 | GLY 181 | 45.51x51 | VdWContact |
| LEU 91 | B2.2 | TYR 182 | 45.52x52 | VdWContact |
| ARG 92 | B2.3 | LEU 175 | - | Hydrophobic |
| ARG 92 | B2.3 | LEU 175 | - | VdWContact |
| ARG 92 | B2.3 | ASP 176 | - | Cationic |
| ARG 92 | B2.3 | ASP 176 | - | HBDonor |
| ARG 92 | B2.3 | ASP 176 | - | VdWContact |
| ARG 92 | B2.3 | ILE 179 | - | Hydrophobic |
| ARG 92 | B2.3 | ILE 179 | - | VdWContact |
| SER 93 | B2.4 | LEU 27 | 1.28x28 | VdWContact |
| PHE 94 | B2.5 | PHE 26 | 1.27x27 | Hydrophobic |
| PHE 94 | B2.5 | PHE 26 | 1.27x27 | VdWContact |
| PHE 94 | B2.5 | HIS 267 | 7.32x31 | Hydrophobic |
| PHE 94 | B2.5 | HIS 267 | 7.32x31 | VdWContact |
| PHE 94 | B2.5 | ILE 270 | 7.35x34 | Hydrophobic |
| PHE 94 | B2.5 | ILE 270 | 7.35x34 | VdWContact |
| PHE 94 | B2.5 | MET 271 | 7.36x35 | Hydrophobic |
| ALA 95 | B2.6 | TRP 87 | 2.60x60 | VdWContact |
| ALA 95 | B2.6 | ILE 179 | - | Hydrophobic |
| LEU 96 | b2b3.2 | LEU 34 | 1.35x35 | Hydrophobic |
| LEU 96 | b2b3.2 | LEU 34 | 1.35x35 | VdWContact |
| LEU 96 | b2b3.2 | TYR 38 | 1.39x39 | Hydrophobic |
| LEU 96 | b2b3.2 | TYR 38 | 1.39x39 | VdWContact |
| LEU 96 | b2b3.2 | GLU 274 | 7.39x38 | Hydrophobic |
| LEU 96 | b2b3.2 | GLU 274 | 7.39x38 | VdWContact |
| PRO 97 | b2b3.3 | TYR 38 | 1.39x39 | VdWContact |
| PRO 97 | b2b3.3 | TRP 87 | 2.60x60 | Hydrophobic |
| PRO 97 | b2b3.3 | TRP 87 | 2.60x60 | VdWContact |
| PRO 97 | b2b3.3 | LEU 106 | 3.29x29 | Hydrophobic |
| PRO 97 | b2b3.3 | LYS 251 | 6.55x55 | HBAcceptor |
| PRO 97 | b2b3.3 | LYS 251 | 6.55x55 | VdWContact |
| PRO 97 | b2b3.3 | TYR 278 | 7.43x42 | Hydrophobic |
| PRO 97 | b2b3.3 | TYR 278 | 7.43x42 | VdWContact |
| LEU 98 | b2b3.4 | TYR 182 | 45.52x52 | VdWContact |
| LEU 98 | b2b3.4 | PHE 247 | 6.51x51 | Hydrophobic |
| LEU 98 | b2b3.4 | LYS 251 | 6.55x55 | Anionic |
| LEU 98 | b2b3.4 | LYS 251 | 6.55x55 | HBAcceptor |
| LEU 98 | b2b3.4 | LYS 251 | 6.55x55 | Hydrophobic |
| LEU 98 | b2b3.4 | LYS 251 | 6.55x55 | VdWContact |
| LEU 98 | b2b3.4 | ARG 254 | 6.58x58 | Anionic |
| LEU 98 | b2b3.4 | ARG 254 | 6.58x58 | VdWContact |
| LEU 98 | b2b3.4 | ILE 270 | 7.35x34 | Hydrophobic |
| LEU 98 | b2b3.4 | ILE 270 | 7.35x34 | VdWContact |
