Predicted complex interactions
CXCL2_HUMAN + CXCR6
SUMMARY
- Chemokine
- CXCL2_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR6 View partner entry
- Partner description
- UniProt: O00574; Gene: cxcr6_human; Family: Chemokine
- Interactions detected
- 94
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm42 | TRP 87 | 2.60x60 | CationPi |
| ALA 1 | NTc.Cm42 | TRP 87 | 2.60x60 | Hydrophobic |
| ALA 1 | NTc.Cm42 | LEU 106 | 3.29x29 | Hydrophobic |
| ALA 1 | NTc.Cm42 | LEU 106 | 3.29x29 | VdWContact |
| ALA 1 | NTc.Cm42 | GLU 274 | 7.39x38 | Cationic |
| ALA 1 | NTc.Cm42 | GLU 274 | 7.39x38 | VdWContact |
| ALA 1 | NTc.Cm42 | TYR 278 | 7.43x42 | VdWContact |
| PRO 2 | NTc.Cm41 | LEU 34 | 1.35x35 | Hydrophobic |
| PRO 2 | NTc.Cm41 | TYR 38 | 1.39x39 | Hydrophobic |
| PRO 2 | NTc.Cm41 | TYR 38 | 1.39x39 | VdWContact |
| PRO 2 | NTc.Cm41 | TRP 87 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm41 | TRP 87 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm41 | GLU 274 | 7.39x38 | VdWContact |
| LEU 3 | NTc.Cm40 | PHE 247 | 6.51x51 | Hydrophobic |
| LEU 3 | NTc.Cm40 | LYS 251 | 6.55x55 | Hydrophobic |
| LEU 3 | NTc.Cm40 | LYS 251 | 6.55x55 | VdWContact |
| LEU 3 | NTc.Cm40 | ARG 254 | 6.58x58 | HBAcceptor |
| LEU 3 | NTc.Cm40 | ARG 254 | 6.58x58 | VdWContact |
| LEU 3 | NTc.Cm40 | ILE 270 | 7.35x34 | Hydrophobic |
| LEU 3 | NTc.Cm40 | GLU 274 | 7.39x38 | HBDonor |
| LEU 3 | NTc.Cm40 | GLU 274 | 7.39x38 | VdWContact |
| ALA 4 | NTc.Cm39 | PHE 26 | 1.27x27 | Hydrophobic |
| ALA 4 | NTc.Cm39 | LEU 34 | 1.35x35 | Hydrophobic |
| ALA 4 | NTc.Cm39 | MET 271 | 7.36x35 | Hydrophobic |
| THR 5 | NTc.Cm38 | LEU 34 | 1.35x35 | Hydrophobic |
| THR 5 | NTc.Cm38 | GLY 91 | 2.64x64 | VdWContact |
| GLU 6 | NTc.Cm37 | ILE 179 | - | Hydrophobic |
| GLU 6 | NTc.Cm37 | ILE 179 | - | VdWContact |
| GLU 6 | NTc.Cm37 | GLY 181 | 45.51x51 | VdWContact |
| GLU 6 | NTc.Cm37 | ARG 254 | 6.58x58 | Anionic |
| GLU 6 | NTc.Cm37 | ARG 254 | 6.58x58 | HBAcceptor |
| GLU 6 | NTc.Cm37 | ARG 254 | 6.58x58 | VdWContact |
| LEU 7 | NTc.Cm36 | HIS 23 | - | VdWContact |
| LEU 7 | NTc.Cm36 | PHE 26 | 1.27x27 | Hydrophobic |
| LEU 7 | NTc.Cm36 | PHE 26 | 1.27x27 | VdWContact |
| LEU 7 | NTc.Cm36 | LEU 27 | 1.28x28 | Hydrophobic |
| LEU 7 | NTc.Cm36 | HIS 267 | 7.32x31 | Hydrophobic |
| LEU 7 | NTc.Cm36 | HIS 267 | 7.32x31 | VdWContact |
| ARG 8 | NTc.Cm35 | HIS 23 | - | HBAcceptor |
| ARG 8 | NTc.Cm35 | HIS 23 | - | VdWContact |
| ARG 8 | NTc.Cm35 | LEU 27 | 1.28x28 | Hydrophobic |
| ARG 8 | NTc.Cm35 | LEU 27 | 1.28x28 | VdWContact |
| ARG 8 | NTc.Cm35 | LYS 177 | - | VdWContact |
| GLN 10 | NTc.Cm33 | PHE 15 | - | VdWContact |
| GLN 10 | NTc.Cm33 | SER 19 | - | VdWContact |
| GLN 10 | NTc.Cm33 | HIS 23 | - | Hydrophobic |
| GLN 10 | NTc.Cm33 | TYR 261 | 7.26x25 | VdWContact |
| GLN 10 | NTc.Cm33 | ALA 262 | 7.27x26 | VdWContact |
| LEU 12 | NTc.Cm31 | ASP 184 | 5.31x32 | VdWContact |
| LEU 12 | NTc.Cm31 | TYR 261 | 7.26x25 | Hydrophobic |
| LEU 12 | NTc.Cm31 | TYR 261 | 7.26x25 | VdWContact |
| LEU 12 | NTc.Cm31 | HIS 267 | 7.32x31 | Hydrophobic |
| GLN 13 | NTc.Cm30 | ASP 184 | 5.31x32 | Hydrophobic |
| GLN 13 | NTc.Cm30 | ASP 184 | 5.31x32 | VdWContact |
| GLN 13 | NTc.Cm30 | TYR 261 | 7.26x25 | Hydrophobic |
| GLN 13 | NTc.Cm30 | TYR 261 | 7.26x25 | VdWContact |
| THR 14 | NTc.Cm29 | ASP 184 | 5.31x32 | HBDonor |
| THR 14 | NTc.Cm29 | ASP 184 | 5.31x32 | VdWContact |
| LEU 15 | NTc.Cm28 | TRP 258 | - | Hydrophobic |
| LEU 15 | NTc.Cm28 | TRP 258 | - | VdWContact |
| GLN 16 | NTc.Cm27 | GLU 185 | 5.32x33 | HBDonor |
| GLN 16 | NTc.Cm27 | GLU 185 | 5.32x33 | VdWContact |
| ILE 18 | NTc.Cm25 | TRP 258 | - | Hydrophobic |
| ILE 18 | NTc.Cm25 | TRP 258 | - | VdWContact |
| LYS 27 | NTc.Cm16 | SER 14 | - | VdWContact |
| LYS 27 | NTc.Cm16 | PHE 15 | - | Hydrophobic |
| LYS 27 | NTc.Cm16 | PHE 15 | - | VdWContact |
| LYS 29 | NTc.Cm14 | PHE 15 | - | Hydrophobic |
| LYS 29 | NTc.Cm14 | PHE 15 | - | VdWContact |
| GLY 32 | NTc.Cm11 | ASP 176 | - | VdWContact |
| HIS 34 | NTc.Cm9 | GLN 24 | 1.25x25 | Hydrophobic |
| HIS 34 | NTc.Cm9 | LEU 27 | 1.28x28 | Hydrophobic |
| HIS 34 | NTc.Cm9 | ASP 176 | - | VdWContact |
| CYS 35 | NTc.Cm8 | ASP 176 | - | VdWContact |
| ALA 36 | NTc.Cm7 | LEU 175 | - | VdWContact |
| ALA 36 | NTc.Cm7 | ASP 176 | - | HBDonor |
| ALA 36 | NTc.Cm7 | ASP 176 | - | Hydrophobic |
| ALA 36 | NTc.Cm7 | ASP 176 | - | VdWContact |
| GLN 37 | NTc.Cm6 | LEU 175 | - | Hydrophobic |
| ILE 41 | NTc.Cm2 | PHE 15 | - | Hydrophobic |
| LYS 45 | CX.5 | GLU 8 | - | Cationic |
| LYS 45 | CX.5 | GLU 8 | - | HBDonor |
| LYS 45 | CX.5 | GLU 8 | - | VdWContact |
| GLN 48 | cxb1.5 | GLU 259 | 7.24x23 | HBDonor |
| GLN 48 | cxb1.5 | GLU 259 | 7.24x23 | VdWContact |
| LYS 49 | cxb1.6 | ALA 262 | 7.27x26 | Hydrophobic |
| ALA 50 | cxb1.8 | TRP 258 | - | Hydrophobic |
| ALA 50 | cxb1.8 | TRP 258 | - | VdWContact |
| CYS 51 | cxb1.10 | TRP 258 | - | Hydrophobic |
| CYS 51 | cxb1.10 | TRP 258 | - | VdWContact |
| MET 66 | b1b2.8 | TYR 10 | - | Hydrophobic |
| MET 66 | b1b2.8 | TYR 10 | - | VdWContact |
| MET 66 | b1b2.8 | PHE 12 | - | Hydrophobic |
| MET 66 | b1b2.8 | PHE 12 | - | VdWContact |
