Predicted complex interactions
CXCL4_HUMAN + CXCR6
SUMMARY
- Chemokine
- CXCL4_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR6 View partner entry
- Partner description
- UniProt: O00574; Gene: cxcr6_human; Family: Chemokine
- Interactions detected
- 87
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| THR 15 | NTc.Cm26 | HIS 183 | - | VdWContact |
| THR 16 | NTc.Cm25 | ASP 184 | 5.31x32 | VdWContact |
| SER 17 | NTc.Cm24 | ASP 184 | 5.31x32 | VdWContact |
| GLN 18 | NTc.Cm23 | ASP 184 | 5.31x32 | HBDonor |
| GLN 18 | NTc.Cm23 | ASP 184 | 5.31x32 | Hydrophobic |
| GLN 18 | NTc.Cm23 | ASP 184 | 5.31x32 | VdWContact |
| GLN 18 | NTc.Cm23 | GLU 185 | 5.32x33 | HBAcceptor |
| GLN 18 | NTc.Cm23 | GLU 185 | 5.32x33 | HBDonor |
| GLN 18 | NTc.Cm23 | GLU 185 | 5.32x33 | Hydrophobic |
| GLN 18 | NTc.Cm23 | GLU 185 | 5.32x33 | VdWContact |
| GLN 18 | NTc.Cm23 | TYR 261 | 7.26x25 | Hydrophobic |
| GLN 18 | NTc.Cm23 | TYR 261 | 7.26x25 | VdWContact |
| VAL 19 | NTc.Cm22 | ALA 262 | 7.27x26 | Hydrophobic |
| VAL 19 | NTc.Cm22 | ALA 262 | 7.27x26 | VdWContact |
| ARG 20 | NTc.Cm21 | ARG 254 | 6.58x58 | VdWContact |
| ARG 20 | NTc.Cm21 | HIS 257 | 6.61x61 | HBDonor |
| ARG 20 | NTc.Cm21 | HIS 257 | 6.61x61 | VdWContact |
| ARG 20 | NTc.Cm21 | TRP 258 | - | Hydrophobic |
| ARG 20 | NTc.Cm21 | TRP 258 | - | VdWContact |
| ARG 20 | NTc.Cm21 | TYR 260 | 7.25x24 | VdWContact |
| ARG 20 | NTc.Cm21 | TYR 261 | 7.26x25 | CationPi |
| ARG 20 | NTc.Cm21 | TYR 261 | 7.26x25 | Hydrophobic |
| ARG 20 | NTc.Cm21 | TYR 261 | 7.26x25 | VdWContact |
| ARG 20 | NTc.Cm21 | ALA 262 | 7.27x26 | VdWContact |
| ARG 20 | NTc.Cm21 | PHE 266 | 7.31x30 | VdWContact |
| PRO 21 | NTc.Cm20 | TRP 258 | - | Hydrophobic |
| PRO 21 | NTc.Cm20 | TRP 258 | - | VdWContact |
| PRO 21 | NTc.Cm20 | GLU 259 | 7.24x23 | VdWContact |
| PRO 21 | NTc.Cm20 | ALA 262 | 7.27x26 | VdWContact |
| ARG 22 | NTc.Cm19 | GLU 259 | 7.24x23 | HBDonor |
| ARG 22 | NTc.Cm19 | GLU 259 | 7.24x23 | VdWContact |
| ARG 22 | NTc.Cm19 | TYR 260 | 7.25x24 | VdWContact |
| ARG 22 | NTc.Cm19 | ALA 262 | 7.27x26 | VdWContact |
| ARG 22 | NTc.Cm19 | MET 263 | 7.28x27 | Hydrophobic |
| ARG 22 | NTc.Cm19 | MET 263 | 7.28x27 | VdWContact |
| ARG 22 | NTc.Cm19 | PHE 266 | 7.31x30 | VdWContact |
| HIS 23 | NTc.Cm18 | HIS 23 | - | Hydrophobic |
| HIS 23 | NTc.Cm18 | HIS 23 | - | PiStacking |
| HIS 23 | NTc.Cm18 | HIS 23 | - | VdWContact |
| HIS 23 | NTc.Cm18 | TYR 261 | 7.26x25 | HBDonor |
| HIS 23 | NTc.Cm18 | TYR 261 | 7.26x25 | VdWContact |
| HIS 23 | NTc.Cm18 | ALA 262 | 7.27x26 | HBDonor |
| HIS 23 | NTc.Cm18 | ALA 262 | 7.27x26 | Hydrophobic |
| HIS 23 | NTc.Cm18 | ALA 262 | 7.27x26 | VdWContact |
| HIS 23 | NTc.Cm18 | MET 263 | 7.28x27 | VdWContact |
| HIS 23 | NTc.Cm18 | THR 264 | 7.29x28 | Hydrophobic |
| HIS 23 | NTc.Cm18 | THR 264 | 7.29x28 | VdWContact |
| HIS 23 | NTc.Cm18 | HIS 267 | 7.32x31 | HBAcceptor |
| HIS 23 | NTc.Cm18 | HIS 267 | 7.32x31 | Hydrophobic |
| HIS 23 | NTc.Cm18 | HIS 267 | 7.32x31 | VdWContact |
| ILE 24 | NTc.Cm17 | ALA 262 | 7.27x26 | Hydrophobic |
| ILE 24 | NTc.Cm17 | ALA 262 | 7.27x26 | VdWContact |
| THR 25 | NTc.Cm16 | ASN 16 | - | Hydrophobic |
| THR 25 | NTc.Cm16 | ASN 16 | - | VdWContact |
| THR 25 | NTc.Cm16 | SER 19 | - | HBDonor |
| THR 25 | NTc.Cm16 | SER 19 | - | VdWContact |
| THR 25 | NTc.Cm16 | GLN 20 | - | HBDonor |
| THR 25 | NTc.Cm16 | GLN 20 | - | Hydrophobic |
| THR 25 | NTc.Cm16 | GLN 20 | - | VdWContact |
| THR 44 | cxb1.1 | GLN 20 | - | VdWContact |
| LYS 46 | cxb1.5 | SER 19 | - | VdWContact |
| LYS 46 | cxb1.5 | GLN 20 | - | VdWContact |
| LYS 46 | cxb1.5 | GLU 22 | - | Cationic |
| LYS 46 | cxb1.5 | GLU 22 | - | HBDonor |
| LYS 46 | cxb1.5 | GLU 22 | - | VdWContact |
| LYS 46 | cxb1.5 | HIS 23 | - | Hydrophobic |
| LYS 46 | cxb1.5 | HIS 23 | - | VdWContact |
| LYS 46 | cxb1.5 | GLN 24 | 1.25x25 | VdWContact |
| LYS 46 | cxb1.5 | THR 264 | 7.29x28 | HBDonor |
| LYS 46 | cxb1.5 | THR 264 | 7.29x28 | VdWContact |
| ASN 47 | cxb1.6 | HIS 23 | - | Hydrophobic |
| ASN 47 | cxb1.6 | HIS 23 | - | VdWContact |
| ASN 47 | cxb1.6 | LEU 27 | 1.28x28 | Hydrophobic |
| ASN 47 | cxb1.6 | LEU 27 | 1.28x28 | VdWContact |
| ARG 49 | cxb1.10 | ASP 176 | - | Cationic |
| ARG 49 | cxb1.10 | ASP 176 | - | Hydrophobic |
| ARG 49 | cxb1.10 | ASP 176 | - | VdWContact |
| ARG 49 | cxb1.10 | LYS 177 | - | VdWContact |
| ARG 49 | cxb1.10 | ILE 179 | - | VdWContact |
| LYS 50 | cxb1.11 | ASP 176 | - | HBDonor |
| LYS 50 | cxb1.11 | ASP 176 | - | VdWContact |
| ILE 51 | cxb1.14 | LEU 175 | - | Hydrophobic |
| LEU 59 | B1.6 | TRP 258 | - | VdWContact |
| LEU 59 | B1.6 | GLU 259 | 7.24x23 | VdWContact |
| TYR 60 | B1.7 | TRP 258 | - | Hydrophobic |
| TYR 60 | B1.7 | TRP 258 | - | VdWContact |
| ILE 63 | b1b2.7 | TRP 258 | - | Hydrophobic |
