Predicted complex interactions
CXCL6_HUMAN + CXCR6
SUMMARY
- Chemokine
- CXCL6_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR6 View partner entry
- Partner description
- UniProt: O00574; Gene: cxcr6_human; Family: Chemokine
- Interactions detected
- 68
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm48 | LEU 106 | 3.29x29 | HBDonor |
| GLY 1 | NTc.Cm48 | LEU 106 | 3.29x29 | VdWContact |
| PRO 2 | NTc.Cm47 | TYR 38 | 1.39x39 | Hydrophobic |
| PRO 2 | NTc.Cm47 | TYR 38 | 1.39x39 | VdWContact |
| PRO 2 | NTc.Cm47 | TRP 87 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm47 | TRP 87 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm47 | GLU 274 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm47 | TYR 278 | 7.43x42 | Hydrophobic |
| PRO 2 | NTc.Cm47 | TYR 278 | 7.43x42 | VdWContact |
| VAL 3 | NTc.Cm46 | PHE 247 | 6.51x51 | Hydrophobic |
| VAL 3 | NTc.Cm46 | LYS 251 | 6.55x55 | Hydrophobic |
| VAL 3 | NTc.Cm46 | ARG 254 | 6.58x58 | VdWContact |
| VAL 3 | NTc.Cm46 | ILE 270 | 7.35x34 | Hydrophobic |
| VAL 3 | NTc.Cm46 | GLU 274 | 7.39x38 | HBDonor |
| VAL 3 | NTc.Cm46 | GLU 274 | 7.39x38 | VdWContact |
| SER 4 | NTc.Cm45 | MET 271 | 7.36x35 | VdWContact |
| SER 4 | NTc.Cm45 | GLU 274 | 7.39x38 | HBDonor |
| SER 4 | NTc.Cm45 | GLU 274 | 7.39x38 | VdWContact |
| ALA 5 | NTc.Cm44 | LEU 34 | 1.35x35 | Hydrophobic |
| ALA 5 | NTc.Cm44 | LEU 34 | 1.35x35 | VdWContact |
| ALA 5 | NTc.Cm44 | TYR 38 | 1.39x39 | Hydrophobic |
| ALA 5 | NTc.Cm44 | TYR 38 | 1.39x39 | VdWContact |
| ALA 5 | NTc.Cm44 | TRP 87 | 2.60x60 | Hydrophobic |
| VAL 6 | NTc.Cm43 | TRP 87 | 2.60x60 | Hydrophobic |
| VAL 6 | NTc.Cm43 | ILE 179 | - | Hydrophobic |
| VAL 6 | NTc.Cm43 | CYS 180 | 45.50x50 | VdWContact |
| VAL 6 | NTc.Cm43 | GLY 181 | 45.51x51 | VdWContact |
| LEU 7 | NTc.Cm42 | PHE 26 | 1.27x27 | Hydrophobic |
| LEU 7 | NTc.Cm42 | HIS 267 | 7.32x31 | Hydrophobic |
| LEU 7 | NTc.Cm42 | HIS 267 | 7.32x31 | VdWContact |
| THR 8 | NTc.Cm41 | LEU 175 | - | Hydrophobic |
| THR 8 | NTc.Cm41 | ILE 179 | - | Hydrophobic |
| THR 8 | NTc.Cm41 | ILE 179 | - | VdWContact |
| GLU 9 | NTc.Cm40 | LEU 27 | 1.28x28 | Hydrophobic |
| GLU 9 | NTc.Cm40 | LYS 177 | - | Anionic |
| GLU 9 | NTc.Cm40 | LYS 177 | - | HBAcceptor |
| GLU 9 | NTc.Cm40 | LYS 177 | - | VdWContact |
| LEU 10 | NTc.Cm39 | HIS 23 | - | HBDonor |
| LEU 10 | NTc.Cm39 | HIS 23 | - | Hydrophobic |
| LEU 10 | NTc.Cm39 | HIS 23 | - | VdWContact |
| LEU 10 | NTc.Cm39 | HIS 267 | 7.32x31 | Hydrophobic |
| LEU 10 | NTc.Cm39 | HIS 267 | 7.32x31 | VdWContact |
| ARG 11 | NTc.Cm38 | ASP 176 | - | Cationic |
| ARG 11 | NTc.Cm38 | ASP 176 | - | HBDonor |
| ARG 11 | NTc.Cm38 | ASP 176 | - | Hydrophobic |
| ARG 11 | NTc.Cm38 | ASP 176 | - | VdWContact |
| LEU 15 | NTc.Cm34 | ASP 176 | - | VdWContact |
| ALA 34 | NTc.Cm15 | TRP 258 | - | Hydrophobic |
| ALA 34 | NTc.Cm15 | TRP 258 | - | VdWContact |
| PRO 36 | NTc.Cm13 | ASP 184 | 5.31x32 | Hydrophobic |
| PRO 36 | NTc.Cm13 | ASP 184 | 5.31x32 | VdWContact |
| PRO 36 | NTc.Cm13 | TYR 261 | 7.26x25 | Hydrophobic |
| PRO 36 | NTc.Cm13 | TYR 261 | 7.26x25 | VdWContact |
| GLN 37 | NTc.Cm12 | LEU 175 | - | Hydrophobic |
| GLN 37 | NTc.Cm12 | LEU 175 | - | VdWContact |
| SER 39 | NTc.Cm10 | ALA 262 | 7.27x26 | VdWContact |
| LYS 40 | NTc.Cm9 | PHE 15 | - | Hydrophobic |
| LYS 40 | NTc.Cm9 | PHE 15 | - | VdWContact |
| GLU 58 | cxb1.11 | PHE 12 | - | Hydrophobic |
| GLU 58 | cxb1.11 | PHE 12 | - | VdWContact |
| GLU 58 | cxb1.11 | PHE 15 | - | Hydrophobic |
| ALA 59 | cxb1.14 | PHE 12 | - | Hydrophobic |
| ALA 59 | cxb1.14 | PHE 12 | - | VdWContact |
| PRO 60 | cxb1.15 | TYR 10 | - | Hydrophobic |
| PRO 60 | cxb1.15 | PHE 12 | - | Hydrophobic |
| PRO 60 | cxb1.15 | PHE 12 | - | VdWContact |
| LYS 64 | B1.3 | TYR 10 | - | HBDonor |
| LYS 64 | B1.3 | TYR 10 | - | VdWContact |
