Predicted complex interactions
CCL18_HUMAN + ACKR3
SUMMARY
- Chemokine
- CCL18_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR3 View partner entry
- Partner description
- UniProt: P25106; Gene: ackr3_human; Family: Chemokine
- Interactions detected
- 134
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 4 | NTc.Cm26 | ASP 16 | - | VdWContact |
| THR 5 | NTc.Cm25 | ASP 16 | - | HBDonor |
| THR 5 | NTc.Cm25 | ASP 16 | - | VdWContact |
| LYS 7 | NTc.Cm23 | ASP 16 | - | HBDonor |
| LYS 7 | NTc.Cm23 | ASP 16 | - | Hydrophobic |
| LYS 7 | NTc.Cm23 | ASP 16 | - | VdWContact |
| LYS 7 | NTc.Cm23 | ILE 17 | - | VdWContact |
| LYS 7 | NTc.Cm23 | SER 18 | - | VdWContact |
| GLU 8 | NTc.Cm22 | SER 18 | - | VdWContact |
| GLU 8 | NTc.Cm22 | TRP 19 | - | Hydrophobic |
| GLU 8 | NTc.Cm22 | TRP 19 | - | VdWContact |
| GLU 8 | NTc.Cm22 | CYS 21 | - | HBAcceptor |
| GLU 8 | NTc.Cm22 | CYS 21 | - | Hydrophobic |
| GLU 8 | NTc.Cm22 | CYS 21 | - | VdWContact |
| LEU 9 | NTc.Cm21 | ILE 17 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | ILE 17 | - | VdWContact |
| LEU 9 | NTc.Cm21 | VAL 29 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | VAL 29 | - | VdWContact |
| LEU 9 | NTc.Cm21 | THR 31 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | THR 31 | - | VdWContact |
| CYS 10 | NTc.Cm20 | TRP 19 | - | Hydrophobic |
| CYS 10 | NTc.Cm20 | TRP 19 | - | VdWContact |
| CYS 10 | NTc.Cm20 | CYS 21 | - | VdWContact |
| CYS 10 | NTc.Cm20 | CYS 26 | - | VdWContact |
| SER 16 | NTc.Cm14 | GLU 202 | - | VdWContact |
| TRP 17 | NTc.Cm13 | ILE 205 | 5.31x32 | Hydrophobic |
| TRP 17 | NTc.Cm13 | ILE 205 | 5.31x32 | VdWContact |
| TRP 17 | NTc.Cm13 | LYS 206 | 5.32x33 | Hydrophobic |
| TRP 17 | NTc.Cm13 | LYS 206 | 5.32x33 | VdWContact |
| TRP 17 | NTc.Cm13 | LEU 209 | 5.35x36 | Hydrophobic |
| ILE 19 | NTc.Cm11 | PHE 6 | - | Hydrophobic |
| ILE 19 | NTc.Cm11 | PHE 6 | - | VdWContact |
| PRO 20 | NTc.Cm10 | PHE 6 | - | Hydrophobic |
| PRO 20 | NTc.Cm10 | PHE 6 | - | VdWContact |
| LYS 22 | NTc.Cm8 | LEU 3 | - | Hydrophobic |
| LYS 22 | NTc.Cm8 | LEU 3 | - | VdWContact |
| LYS 22 | NTc.Cm8 | LEU 5 | - | Hydrophobic |
| LYS 22 | NTc.Cm8 | LEU 5 | - | VdWContact |
| LYS 22 | NTc.Cm8 | PHE 6 | - | Hydrophobic |
| LYS 22 | NTc.Cm8 | PHE 6 | - | VdWContact |
| PHE 23 | NTc.Cm7 | LEU 5 | - | Hydrophobic |
| PHE 23 | NTc.Cm7 | LEU 5 | - | VdWContact |
| PHE 23 | NTc.Cm7 | PHE 6 | - | Hydrophobic |
| PHE 23 | NTc.Cm7 | PHE 6 | - | PiStacking |
| PHE 23 | NTc.Cm7 | PHE 6 | - | VdWContact |
| PHE 23 | NTc.Cm7 | HIS 281 | 6.64x64 | Hydrophobic |
| SER 28 | NTc.Cm2 | VAL 28 | - | VdWContact |
| SER 28 | NTc.Cm2 | VAL 29 | - | VdWContact |
| SER 28 | NTc.Cm2 | ASP 30 | - | HBDonor |
| SER 28 | NTc.Cm2 | ASP 30 | - | VdWContact |
| GLU 29 | NTc.Cm1 | ILE 27 | - | Hydrophobic |
| GLU 29 | NTc.Cm1 | ILE 27 | - | VdWContact |
| GLU 29 | NTc.Cm1 | VAL 28 | - | VdWContact |
| THR 30 | CX.1 | CYS 26 | - | Hydrophobic |
| THR 30 | CX.1 | CYS 26 | - | VdWContact |
| THR 30 | CX.1 | ILE 27 | - | HBAcceptor |
| THR 30 | CX.1 | ILE 27 | - | VdWContact |
| THR 30 | CX.1 | VAL 28 | - | VdWContact |
| THR 30 | CX.1 | VAL 29 | - | HBAcceptor |
| THR 30 | CX.1 | VAL 29 | - | Hydrophobic |
| THR 30 | CX.1 | VAL 29 | - | VdWContact |
| SER 31 | CX.5 | CYS 21 | - | VdWContact |
| SER 31 | CX.5 | CYS 26 | - | VdWContact |
| SER 31 | CX.5 | ILE 27 | - | VdWContact |
| SER 31 | CX.5 | VAL 28 | - | VdWContact |
| PRO 32 | cxb1.1 | SER 24 | - | VdWContact |
| PRO 32 | cxb1.1 | ASP 25 | - | VdWContact |
| PRO 32 | cxb1.1 | CYS 26 | - | HBAcceptor |
| PRO 32 | cxb1.1 | CYS 26 | - | VdWContact |
| PRO 32 | cxb1.1 | ILE 27 | - | VdWContact |
| GLN 33 | cxb1.2 | CYS 21 | - | Hydrophobic |
| GLN 33 | cxb1.2 | CYS 21 | - | VdWContact |
| GLN 33 | cxb1.2 | ASN 22 | - | HBAcceptor |
| GLN 33 | cxb1.2 | ASN 22 | - | VdWContact |
| GLN 33 | cxb1.2 | SER 23 | - | HBAcceptor |
| GLN 33 | cxb1.2 | SER 23 | - | VdWContact |
| GLN 33 | cxb1.2 | CYS 26 | - | VdWContact |
| CYS 34 | cxb1.5 | CYS 21 | - | VdWContact |
| CYS 34 | cxb1.5 | SER 23 | - | HBAcceptor |
| CYS 34 | cxb1.5 | SER 23 | - | VdWContact |
| CYS 34 | cxb1.5 | CYS 26 | - | HBDonor |
| CYS 34 | cxb1.5 | CYS 26 | - | Hydrophobic |
| CYS 34 | cxb1.5 | CYS 26 | - | VdWContact |
| PRO 37 | cxb1.8 | ASP 25 | - | Hydrophobic |
| PRO 37 | cxb1.8 | ASP 25 | - | VdWContact |
| PRO 37 | cxb1.8 | ILE 27 | - | Hydrophobic |
| GLY 38 | cxb1.10 | VAL 29 | - | VdWContact |
| VAL 39 | cxb1.11 | VAL 29 | - | VdWContact |
| ILE 40 | cxb1.14 | VAL 29 | - | Hydrophobic |
| ILE 40 | cxb1.14 | VAL 29 | - | VdWContact |
| ILE 40 | cxb1.14 | ASP 30 | - | Hydrophobic |
| ILE 40 | cxb1.14 | ASP 30 | - | VdWContact |
| ILE 40 | cxb1.14 | THR 31 | - | Hydrophobic |
| ILE 40 | cxb1.14 | THR 31 | - | VdWContact |
| LEU 42 | cxb1.16 | PHE 14 | - | Hydrophobic |
| LEU 42 | cxb1.16 | PHE 14 | - | VdWContact |
| LEU 42 | cxb1.16 | ASP 30 | - | Hydrophobic |
| LEU 42 | cxb1.16 | ASP 30 | - | VdWContact |
| THR 43 | B1.1 | TYR 8 | - | VdWContact |
| LYS 44 | B1.2 | LEU 3 | - | VdWContact |
| LYS 44 | B1.2 | TYR 8 | - | Hydrophobic |
| LYS 44 | B1.2 | TYR 8 | - | VdWContact |
| ARG 45 | B1.3 | ASP 7 | - | HBDonor |
| ARG 45 | B1.3 | ASP 7 | - | VdWContact |
| ARG 45 | B1.3 | TYR 8 | - | Hydrophobic |
| ARG 45 | B1.3 | TYR 8 | - | VdWContact |
| ARG 45 | B1.3 | SER 9 | - | VdWContact |
| ARG 45 | B1.3 | GLU 10 | - | VdWContact |
| ARG 45 | B1.3 | GLY 12 | - | VdWContact |
| ARG 45 | B1.3 | PRO 284 | - | VdWContact |
| ARG 45 | B1.3 | PHE 285 | - | Hydrophobic |
| ARG 45 | B1.3 | PHE 285 | - | VdWContact |
| ARG 45 | B1.3 | THR 286 | 7.24x23 | HBDonor |
| ARG 45 | B1.3 | THR 286 | 7.24x23 | Hydrophobic |
| ARG 45 | B1.3 | THR 286 | 7.24x23 | VdWContact |
| GLY 46 | B1.4 | VAL 32 | - | VdWContact |
| GLY 46 | B1.4 | PHE 285 | - | VdWContact |
| ARG 47 | B1.5 | SER 278 | 6.61x61 | HBDonor |
| ARG 47 | B1.5 | SER 278 | 6.61x61 | VdWContact |
| ARG 47 | B1.5 | HIS 281 | 6.64x64 | VdWContact |
| ARG 47 | B1.5 | PHE 285 | - | Hydrophobic |
| ARG 47 | B1.5 | PHE 285 | - | VdWContact |
| ARG 47 | B1.5 | GLU 290 | 7.28x27 | Cationic |
| ARG 47 | B1.5 | GLU 290 | 7.28x27 | HBDonor |
| ARG 47 | B1.5 | GLU 290 | 7.28x27 | VdWContact |
| GLN 48 | B1.6 | PHE 14 | - | VdWContact |
| GLN 48 | B1.6 | ASP 30 | - | Hydrophobic |
| GLN 48 | B1.6 | ASP 30 | - | VdWContact |
| GLN 48 | B1.6 | THR 31 | - | VdWContact |
| GLN 48 | B1.6 | VAL 32 | - | Hydrophobic |
| GLN 48 | B1.6 | VAL 32 | - | VdWContact |
| ILE 49 | B1.7 | HIS 281 | 6.64x64 | Hydrophobic |
| ILE 49 | B1.7 | HIS 281 | 6.64x64 | VdWContact |
| PRO 53 | b1b2.10 | ILE 27 | - | Hydrophobic |
