Predicted complex interactions
CXCL8_HUMAN + CXCR6
SUMMARY
- Chemokine
- CXCL8_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR6 View partner entry
- Partner description
- UniProt: O00574; Gene: cxcr6_human; Family: Chemokine
- Interactions detected
- 68
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LYS 18 | NTc.Cm16 | ASN 174 | - | HBDonor |
| LYS 18 | NTc.Cm16 | ASN 174 | - | VdWContact |
| LYS 18 | NTc.Cm16 | ASP 176 | - | Cationic |
| TYR 20 | NTc.Cm14 | PHE 173 | - | Hydrophobic |
| TYR 20 | NTc.Cm14 | LEU 175 | - | Hydrophobic |
| TYR 20 | NTc.Cm14 | LEU 175 | - | VdWContact |
| LYS 22 | NTc.Cm12 | ASN 171 | - | VdWContact |
| LYS 22 | NTc.Cm12 | VAL 172 | - | VdWContact |
| LYS 22 | NTc.Cm12 | PHE 173 | - | HBDonor |
| LYS 22 | NTc.Cm12 | PHE 173 | - | VdWContact |
| PRO 23 | NTc.Cm11 | ASP 184 | 5.31x32 | Hydrophobic |
| PRO 23 | NTc.Cm11 | GLU 185 | 5.32x33 | Hydrophobic |
| HIS 25 | NTc.Cm9 | TRP 258 | - | Hydrophobic |
| HIS 25 | NTc.Cm9 | TRP 258 | - | VdWContact |
| HIS 25 | NTc.Cm9 | GLU 259 | 7.24x23 | HBDonor |
| HIS 25 | NTc.Cm9 | GLU 259 | 7.24x23 | VdWContact |
| HIS 25 | NTc.Cm9 | TYR 261 | 7.26x25 | Hydrophobic |
| HIS 25 | NTc.Cm9 | TYR 261 | 7.26x25 | VdWContact |
| HIS 25 | NTc.Cm9 | ALA 262 | 7.27x26 | Hydrophobic |
| HIS 25 | NTc.Cm9 | ALA 262 | 7.27x26 | VdWContact |
| PRO 26 | NTc.Cm8 | ALA 262 | 7.27x26 | Hydrophobic |
| PRO 26 | NTc.Cm8 | ALA 262 | 7.27x26 | VdWContact |
| LYS 27 | NTc.Cm7 | HIS 23 | - | Hydrophobic |
| LYS 27 | NTc.Cm7 | HIS 23 | - | VdWContact |
| LYS 27 | NTc.Cm7 | TYR 261 | 7.26x25 | VdWContact |
| LYS 27 | NTc.Cm7 | ALA 262 | 7.27x26 | Hydrophobic |
| LYS 27 | NTc.Cm7 | ALA 262 | 7.27x26 | VdWContact |
| LYS 27 | NTc.Cm7 | MET 263 | 7.28x27 | HBDonor |
| LYS 27 | NTc.Cm7 | MET 263 | 7.28x27 | VdWContact |
| LYS 27 | NTc.Cm7 | THR 264 | 7.29x28 | VdWContact |
| LYS 27 | NTc.Cm7 | PHE 266 | 7.31x30 | VdWContact |
| LYS 27 | NTc.Cm7 | HIS 267 | 7.32x31 | CationPi |
| LYS 27 | NTc.Cm7 | HIS 267 | 7.32x31 | Hydrophobic |
| LYS 27 | NTc.Cm7 | HIS 267 | 7.32x31 | VdWContact |
| PHE 28 | NTc.Cm6 | HIS 23 | - | Hydrophobic |
| PHE 28 | NTc.Cm6 | TYR 261 | 7.26x25 | Hydrophobic |
| PHE 28 | NTc.Cm6 | TYR 261 | 7.26x25 | VdWContact |
| PHE 28 | NTc.Cm6 | HIS 267 | 7.32x31 | Hydrophobic |
| PHE 28 | NTc.Cm6 | HIS 267 | 7.32x31 | VdWContact |
| LYS 30 | NTc.Cm4 | GLN 20 | - | HBDonor |
| LYS 30 | NTc.Cm4 | GLN 20 | - | Hydrophobic |
| LYS 30 | NTc.Cm4 | GLN 20 | - | VdWContact |
| SER 51 | B1.4 | HIS 23 | - | VdWContact |
| SER 51 | B1.4 | GLN 24 | 1.25x25 | HBAcceptor |
| SER 51 | B1.4 | GLN 24 | 1.25x25 | VdWContact |
| ASP 52 | B1.5 | LEU 27 | 1.28x28 | Hydrophobic |
| ASP 52 | B1.5 | LEU 27 | 1.28x28 | VdWContact |
| ARG 54 | B1.7 | LEU 175 | - | HBDonor |
| ARG 54 | B1.7 | LEU 175 | - | VdWContact |
| ARG 54 | B1.7 | ASP 176 | - | Hydrophobic |
| ARG 54 | B1.7 | ASP 176 | - | VdWContact |
| ARG 54 | B1.7 | ILE 179 | - | VdWContact |
| LEU 56 | b1b2.6 | LEU 175 | - | Hydrophobic |
| LEU 56 | b1b2.6 | LEU 175 | - | VdWContact |
| ARG 67 | B2.3 | TRP 258 | - | Hydrophobic |
| ARG 67 | B2.3 | TRP 258 | - | VdWContact |
| VAL 68 | B2.4 | TRP 258 | - | Hydrophobic |
| LYS 71 | b2b3.2 | TRP 258 | - | Hydrophobic |
| LYS 71 | b2b3.2 | TRP 258 | - | VdWContact |
| LYS 71 | b2b3.2 | GLU 259 | 7.24x23 | Cationic |
| LYS 71 | b2b3.2 | GLU 259 | 7.24x23 | HBDonor |
| LYS 71 | b2b3.2 | GLU 259 | 7.24x23 | VdWContact |
| ARG 75 | B3.1 | SER 19 | - | VdWContact |
| ALA 76 | B3.2 | PHE 12 | - | Hydrophobic |
| GLU 77 | B3.3 | PHE 12 | - | Hydrophobic |
| SER 79 | b3h.1 | PHE 12 | - | VdWContact |
| SER 79 | b3h.1 | PHE 15 | - | HBAcceptor |
| SER 79 | b3h.1 | PHE 15 | - | VdWContact |
