Predicted complex interactions
CXCL9_HUMAN + CXCR6
SUMMARY
- Chemokine
- CXCL9_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR6 View partner entry
- Partner description
- UniProt: O00574; Gene: cxcr6_human; Family: Chemokine
- Interactions detected
- 95
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| THR 1 | NTc.Cm30 | LEU 106 | 3.29x29 | Hydrophobic |
| THR 1 | NTc.Cm30 | LEU 106 | 3.29x29 | VdWContact |
| THR 1 | NTc.Cm30 | TYR 109 | 3.32x32 | Hydrophobic |
| THR 1 | NTc.Cm30 | TYR 109 | 3.32x32 | VdWContact |
| THR 1 | NTc.Cm30 | TYR 182 | 45.52x52 | Hydrophobic |
| THR 1 | NTc.Cm30 | TYR 182 | 45.52x52 | VdWContact |
| THR 1 | NTc.Cm30 | GLU 274 | 7.39x38 | Cationic |
| THR 1 | NTc.Cm30 | TYR 278 | 7.43x42 | VdWContact |
| PRO 2 | NTc.Cm29 | TRP 87 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm29 | TRP 87 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm29 | GLU 274 | 7.39x38 | VdWContact |
| VAL 3 | NTc.Cm28 | LYS 251 | 6.55x55 | Hydrophobic |
| VAL 3 | NTc.Cm28 | TYR 261 | 7.26x25 | Hydrophobic |
| VAL 3 | NTc.Cm28 | ILE 270 | 7.35x34 | Hydrophobic |
| VAL 3 | NTc.Cm28 | GLU 274 | 7.39x38 | HBDonor |
| VAL 3 | NTc.Cm28 | GLU 274 | 7.39x38 | VdWContact |
| VAL 4 | NTc.Cm27 | PHE 26 | 1.27x27 | Hydrophobic |
| VAL 4 | NTc.Cm27 | LEU 34 | 1.35x35 | Hydrophobic |
| VAL 4 | NTc.Cm27 | ILE 270 | 7.35x34 | Hydrophobic |
| VAL 4 | NTc.Cm27 | MET 271 | 7.36x35 | Hydrophobic |
| VAL 4 | NTc.Cm27 | MET 271 | 7.36x35 | VdWContact |
| ARG 5 | NTc.Cm26 | TRP 87 | 2.60x60 | VdWContact |
| ARG 5 | NTc.Cm26 | TRP 95 | 23.50x50 | VdWContact |
| ARG 5 | NTc.Cm26 | ILE 179 | - | Hydrophobic |
| ARG 5 | NTc.Cm26 | CYS 180 | 45.50x50 | Cationic |
| ARG 5 | NTc.Cm26 | CYS 180 | 45.50x50 | VdWContact |
| LYS 6 | NTc.Cm25 | LYS 31 | 1.32x32 | VdWContact |
| LYS 6 | NTc.Cm25 | GLY 91 | 2.64x64 | HBDonor |
| LYS 6 | NTc.Cm25 | GLY 91 | 2.64x64 | VdWContact |
| LYS 6 | NTc.Cm25 | ILE 179 | - | VdWContact |
| GLY 7 | NTc.Cm24 | ILE 179 | - | VdWContact |
| ARG 8 | NTc.Cm23 | PHE 173 | - | HBDonor |
| ARG 8 | NTc.Cm23 | PHE 173 | - | VdWContact |
| ARG 8 | NTc.Cm23 | ASN 174 | - | HBDonor |
| ARG 8 | NTc.Cm23 | ASN 174 | - | VdWContact |
| ARG 8 | NTc.Cm23 | LEU 175 | - | HBDonor |
| ARG 8 | NTc.Cm23 | LEU 175 | - | Hydrophobic |
| ARG 8 | NTc.Cm23 | LEU 175 | - | VdWContact |
| ARG 8 | NTc.Cm23 | ASP 176 | - | HBDonor |
| ARG 8 | NTc.Cm23 | ASP 176 | - | Hydrophobic |
| ARG 8 | NTc.Cm23 | ASP 176 | - | VdWContact |
| ARG 8 | NTc.Cm23 | LYS 177 | - | VdWContact |
| ARG 8 | NTc.Cm23 | LEU 178 | - | VdWContact |
| ARG 8 | NTc.Cm23 | ILE 179 | - | Hydrophobic |
| ARG 8 | NTc.Cm23 | ILE 179 | - | VdWContact |
| CYS 9 | NTc.Cm22 | LEU 175 | - | VdWContact |
| CYS 9 | NTc.Cm22 | ASP 176 | - | HBDonor |
| CYS 9 | NTc.Cm22 | ASP 176 | - | VdWContact |
| SER 10 | NTc.Cm21 | LEU 175 | - | VdWContact |
| ILE 12 | NTc.Cm19 | LEU 175 | - | Hydrophobic |
| ILE 12 | NTc.Cm19 | LEU 175 | - | VdWContact |
| LYS 28 | NTc.Cm3 | GLU 185 | 5.32x33 | Cationic |
| LYS 28 | NTc.Cm3 | TRP 258 | - | Hydrophobic |
| GLN 29 | NTc.Cm2 | PHE 12 | - | Hydrophobic |
| GLN 29 | NTc.Cm2 | PHE 12 | - | VdWContact |
| PHE 30 | NTc.Cm1 | TRP 258 | - | Hydrophobic |
| ALA 31 | CX.1 | PHE 15 | - | Hydrophobic |
| ALA 31 | CX.1 | PHE 15 | - | VdWContact |
| ALA 31 | CX.1 | ALA 262 | 7.27x26 | Hydrophobic |
| ALA 31 | CX.1 | ALA 262 | 7.27x26 | VdWContact |
| PRO 32 | CX.4 | GLN 20 | - | Hydrophobic |
| PRO 32 | CX.4 | HIS 23 | - | Hydrophobic |
| PRO 32 | CX.4 | HIS 23 | - | VdWContact |
| SER 33 | CX.5 | HIS 23 | - | HBAcceptor |
| SER 33 | CX.5 | HIS 23 | - | VdWContact |
| SER 33 | CX.5 | HIS 267 | 7.32x31 | VdWContact |
| PRO 34 | cxb1.1 | HIS 23 | - | VdWContact |
| PRO 34 | cxb1.1 | PHE 26 | 1.27x27 | Hydrophobic |
| PRO 34 | cxb1.1 | PHE 26 | 1.27x27 | VdWContact |
| PRO 34 | cxb1.1 | LEU 27 | 1.28x28 | VdWContact |
| PRO 34 | cxb1.1 | HIS 267 | 7.32x31 | Hydrophobic |
| PRO 34 | cxb1.1 | HIS 267 | 7.32x31 | VdWContact |
| SER 35 | cxb1.2 | TYR 261 | 7.26x25 | VdWContact |
| GLU 37 | cxb1.6 | LEU 27 | 1.28x28 | Hydrophobic |
| GLU 37 | cxb1.6 | LEU 27 | 1.28x28 | VdWContact |
| GLU 37 | cxb1.6 | LYS 177 | - | Anionic |
| LYS 38 | cxb1.7 | ASP 176 | - | Cationic |
| ILE 64 | B2.3 | PHE 12 | - | Hydrophobic |
| ILE 64 | B2.3 | PHE 12 | - | VdWContact |
| GLU 68 | b2b3.2 | PHE 12 | - | Hydrophobic |
| LYS 74 | B3.3 | HIS 7 | - | Hydrophobic |
| LYS 74 | B3.3 | HIS 7 | - | VdWContact |
| LYS 75 | B3.4 | HIS 7 | - | Hydrophobic |
| LYS 75 | B3.4 | HIS 7 | - | VdWContact |
| LYS 75 | B3.4 | ASP 9 | - | Cationic |
| LYS 75 | B3.4 | ASP 9 | - | HBDonor |
| LYS 75 | B3.4 | ASP 9 | - | VdWContact |
| LYS 78 | b3h.3 | ASP 5 | - | Cationic |
| LYS 78 | b3h.3 | ASP 5 | - | HBDonor |
| LYS 78 | b3h.3 | ASP 5 | - | Hydrophobic |
| LYS 78 | b3h.3 | ASP 5 | - | VdWContact |
| LYS 78 | b3h.3 | HIS 7 | - | Hydrophobic |
| LYS 78 | b3h.3 | HIS 7 | - | VdWContact |
| LYS 82 | H.3 | HIS 4 | - | CationPi |
| LYS 82 | H.3 | HIS 4 | - | VdWContact |
