Predicted complex interactions
CCL19_HUMAN + ACKR3
SUMMARY
- Chemokine
- CCL19_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR3 View partner entry
- Partner description
- UniProt: P25106; Gene: ackr3_human; Family: Chemokine
- Interactions detected
- 135
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm28 | GLU 213 | 5.39x40 | Cationic |
| GLY 1 | NTc.Cm28 | GLU 213 | 5.39x40 | HBDonor |
| GLY 1 | NTc.Cm28 | GLU 213 | 5.39x40 | VdWContact |
| GLY 1 | NTc.Cm28 | ASP 275 | 6.58x58 | Cationic |
| GLY 1 | NTc.Cm28 | ASP 275 | 6.58x58 | HBDonor |
| GLY 1 | NTc.Cm28 | ASP 275 | 6.58x58 | VdWContact |
| THR 2 | NTc.Cm27 | PHE 294 | 7.32x31 | Hydrophobic |
| THR 2 | NTc.Cm27 | PHE 294 | 7.32x31 | VdWContact |
| THR 2 | NTc.Cm27 | LEU 297 | 7.35x34 | Hydrophobic |
| THR 2 | NTc.Cm27 | HIS 298 | 7.36x35 | Hydrophobic |
| THR 2 | NTc.Cm27 | HIS 298 | 7.36x35 | VdWContact |
| ASP 4 | NTc.Cm25 | ASN 108 | - | HBAcceptor |
| ASP 4 | NTc.Cm25 | ASN 108 | - | Hydrophobic |
| ASP 4 | NTc.Cm25 | ASN 108 | - | VdWContact |
| ASP 4 | NTc.Cm25 | TYR 195 | - | Hydrophobic |
| ASP 4 | NTc.Cm25 | ARG 197 | 45.51x51 | Anionic |
| ASP 4 | NTc.Cm25 | ARG 197 | 45.51x51 | VdWContact |
| ASP 4 | NTc.Cm25 | PHE 294 | 7.32x31 | VdWContact |
| ALA 5 | NTc.Cm24 | ARG 197 | 45.51x51 | HBAcceptor |
| ALA 5 | NTc.Cm24 | ARG 197 | 45.51x51 | VdWContact |
| GLU 6 | NTc.Cm23 | ASN 36 | - | Hydrophobic |
| GLU 6 | NTc.Cm23 | ASN 36 | - | VdWContact |
| GLU 6 | NTc.Cm23 | LYS 40 | - | Anionic |
| GLU 6 | NTc.Cm23 | LYS 40 | - | HBAcceptor |
| GLU 6 | NTc.Cm23 | LYS 40 | - | VdWContact |
| ASP 7 | NTc.Cm22 | MET 33 | - | Hydrophobic |
| ASP 7 | NTc.Cm22 | MET 33 | - | VdWContact |
| ASP 7 | NTc.Cm22 | SER 190 | - | HBAcceptor |
| ASP 7 | NTc.Cm22 | SER 190 | - | VdWContact |
| CYS 9 | NTc.Cm20 | THR 31 | - | Hydrophobic |
| CYS 9 | NTc.Cm20 | THR 31 | - | VdWContact |
| LEU 10 | NTc.Cm19 | THR 31 | - | VdWContact |
| LEU 10 | NTc.Cm19 | PHE 285 | - | Hydrophobic |
| LEU 10 | NTc.Cm19 | PHE 285 | - | VdWContact |
| LEU 10 | NTc.Cm19 | GLU 290 | 7.28x27 | Hydrophobic |
| LEU 10 | NTc.Cm19 | GLU 290 | 7.28x27 | VdWContact |
| SER 11 | NTc.Cm18 | ASP 30 | - | VdWContact |
| SER 11 | NTc.Cm18 | THR 31 | - | VdWContact |
| SER 11 | NTc.Cm18 | PHE 285 | - | VdWContact |
| VAL 12 | NTc.Cm17 | ASP 30 | - | Hydrophobic |
| VAL 12 | NTc.Cm17 | ASP 30 | - | VdWContact |
| VAL 12 | NTc.Cm17 | THR 31 | - | Hydrophobic |
| VAL 12 | NTc.Cm17 | THR 31 | - | VdWContact |
| VAL 12 | NTc.Cm17 | HIS 281 | 6.64x64 | Hydrophobic |
| THR 13 | NTc.Cm16 | VAL 29 | - | HBDonor |
| THR 13 | NTc.Cm16 | VAL 29 | - | VdWContact |
| THR 13 | NTc.Cm16 | ASP 30 | - | HBDonor |
| THR 13 | NTc.Cm16 | ASP 30 | - | VdWContact |
| GLN 14 | NTc.Cm15 | VAL 28 | - | Hydrophobic |
| GLN 14 | NTc.Cm15 | VAL 28 | - | VdWContact |
| LYS 15 | NTc.Cm14 | SER 15 | - | HBDonor |
| LYS 15 | NTc.Cm14 | SER 15 | - | VdWContact |
| LYS 15 | NTc.Cm14 | VAL 28 | - | VdWContact |
| LYS 15 | NTc.Cm14 | VAL 29 | - | HBAcceptor |
| LYS 15 | NTc.Cm14 | VAL 29 | - | VdWContact |
| PRO 16 | NTc.Cm13 | CYS 21 | - | VdWContact |
| PRO 16 | NTc.Cm13 | CYS 26 | - | Hydrophobic |
| PRO 16 | NTc.Cm13 | CYS 26 | - | VdWContact |
| PRO 16 | NTc.Cm13 | ILE 27 | - | VdWContact |
| PRO 16 | NTc.Cm13 | VAL 28 | - | Hydrophobic |
| PRO 16 | NTc.Cm13 | VAL 28 | - | VdWContact |
| ILE 17 | NTc.Cm12 | TRP 19 | - | Hydrophobic |
| ILE 17 | NTc.Cm12 | TRP 19 | - | VdWContact |
| ILE 17 | NTc.Cm12 | CYS 26 | - | VdWContact |
| ILE 17 | NTc.Cm12 | ILE 27 | - | HBAcceptor |
| ILE 17 | NTc.Cm12 | ILE 27 | - | HBDonor |
| ILE 17 | NTc.Cm12 | ILE 27 | - | Hydrophobic |
| ILE 17 | NTc.Cm12 | ILE 27 | - | VdWContact |
| ILE 17 | NTc.Cm12 | VAL 29 | - | Hydrophobic |
| ILE 17 | NTc.Cm12 | VAL 29 | - | VdWContact |
| PRO 18 | NTc.Cm11 | TRP 19 | - | Hydrophobic |
| PRO 18 | NTc.Cm11 | TRP 19 | - | VdWContact |
| PRO 18 | NTc.Cm11 | ILE 27 | - | VdWContact |
| GLY 19 | NTc.Cm10 | ASP 25 | - | HBDonor |
| GLY 19 | NTc.Cm10 | ASP 25 | - | VdWContact |
| GLY 19 | NTc.Cm10 | ILE 27 | - | VdWContact |
| ILE 21 | NTc.Cm8 | TRP 19 | - | Hydrophobic |
| ILE 21 | NTc.Cm8 | TRP 19 | - | VdWContact |
| VAL 22 | NTc.Cm7 | ILE 27 | - | Hydrophobic |
| LEU 28 | NTc.Cm1 | MET 33 | - | Hydrophobic |
| LEU 28 | NTc.Cm1 | MET 33 | - | VdWContact |
| ILE 30 | CX.5 | VAL 186 | - | VdWContact |
| ILE 30 | CX.5 | PHE 199 | - | Hydrophobic |
| ILE 30 | CX.5 | PHE 199 | - | VdWContact |
| ILE 30 | CX.5 | GLU 202 | - | Hydrophobic |
| ILE 30 | CX.5 | ILE 205 | 5.31x32 | Hydrophobic |
| ILE 30 | CX.5 | ILE 205 | 5.31x32 | VdWContact |
| LYS 31 | cxb1.1 | VAL 186 | - | VdWContact |
| LYS 31 | cxb1.1 | PHE 199 | - | Hydrophobic |
| LYS 31 | cxb1.1 | PHE 199 | - | VdWContact |
| GLY 33 | cxb1.5 | ARG 197 | 45.51x51 | VdWContact |
| ARG 35 | cxb1.8 | ILE 205 | 5.31x32 | VdWContact |
| ARG 35 | cxb1.8 | LEU 209 | 5.35x36 | Hydrophobic |
| ARG 35 | cxb1.8 | GLU 213 | 5.39x40 | Cationic |
| ARG 35 | cxb1.8 | ASP 275 | 6.58x58 | Cationic |
| PRO 37 | cxb1.10 | ILE 205 | 5.31x32 | Hydrophobic |
| PRO 37 | cxb1.10 | ILE 205 | 5.31x32 | VdWContact |
| VAL 40 | cxb1.15 | MET 33 | - | Hydrophobic |
| PHE 41 | cxb1.16 | ILE 27 | - | Hydrophobic |
| ARG 45 | B1.4 | LEU 3 | - | HBDonor |
| ARG 45 | B1.4 | LEU 3 | - | VdWContact |
| ARG 45 | B1.4 | PHE 6 | - | HBDonor |
| ARG 45 | B1.4 | PHE 6 | - | VdWContact |
| ARG 45 | B1.4 | TYR 8 | - | VdWContact |
| ARG 47 | B1.6 | TYR 8 | - | HBDonor |
| ARG 47 | B1.6 | TYR 8 | - | VdWContact |
| ARG 47 | B1.6 | GLU 10 | - | HBDonor |
| ARG 47 | B1.6 | GLU 10 | - | VdWContact |
| ARG 47 | B1.6 | PHE 14 | - | Hydrophobic |
| ARG 47 | B1.6 | PHE 14 | - | VdWContact |
| GLN 48 | B1.7 | MET 33 | - | Hydrophobic |
| GLN 48 | B1.7 | MET 33 | - | VdWContact |
| LEU 49 | b1b2.4 | PHE 14 | - | Hydrophobic |
| LEU 49 | b1b2.4 | PHE 14 | - | VdWContact |
| LEU 49 | b1b2.4 | VAL 29 | - | Hydrophobic |
| LEU 49 | b1b2.4 | VAL 29 | - | VdWContact |
| CYS 50 | b1b2.6 | ASP 30 | - | HBAcceptor |
| CYS 50 | b1b2.6 | ASP 30 | - | VdWContact |
| CYS 50 | b1b2.6 | THR 31 | - | HBAcceptor |
| CYS 50 | b1b2.6 | THR 31 | - | HBDonor |
| CYS 50 | b1b2.6 | THR 31 | - | Hydrophobic |
| CYS 50 | b1b2.6 | THR 31 | - | VdWContact |
| PRO 52 | b1b2.8 | ASP 30 | - | Hydrophobic |
| PRO 52 | b1b2.8 | ASP 30 | - | VdWContact |
| TRP 57 | b1b2.14 | ILE 27 | - | Hydrophobic |
| TRP 57 | b1b2.14 | ILE 27 | - | VdWContact |
| TRP 57 | b1b2.14 | VAL 28 | - | Hydrophobic |
| TRP 57 | b1b2.14 | VAL 28 | - | VdWContact |
| ARG 60 | B2.2 | SER 24 | - | HBDonor |
| ARG 60 | B2.2 | SER 24 | - | VdWContact |
| ILE 61 | B2.3 | ILE 27 | - | Hydrophobic |
| ILE 61 | B2.3 | ILE 27 | - | VdWContact |
| ARG 64 | B2.6 | ASP 25 | - | Cationic |
| ARG 64 | B2.6 | ASP 25 | - | HBDonor |
| ARG 64 | B2.6 | ASP 25 | - | VdWContact |
