Predicted complex interactions
CCL2_HUMAN + ACKR3
SUMMARY
- Chemokine
- CCL2_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR3 View partner entry
- Partner description
- UniProt: P25106; Gene: ackr3_human; Family: Chemokine
- Interactions detected
- 81
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm33 | TRP 100 | 2.60x60 | VdWContact |
| GLN 1 | NTc.Cm33 | HIS 121 | 3.29x29 | Hydrophobic |
| GLN 1 | NTc.Cm33 | HIS 121 | 3.29x29 | VdWContact |
| GLN 1 | NTc.Cm33 | PHE 124 | 3.32x32 | Hydrophobic |
| GLN 1 | NTc.Cm33 | PHE 124 | 3.32x32 | VdWContact |
| GLN 1 | NTc.Cm33 | ASP 179 | 4.60x61 | Cationic |
| GLN 1 | NTc.Cm33 | ASP 179 | 4.60x61 | HBDonor |
| GLN 1 | NTc.Cm33 | ASP 179 | 4.60x61 | VdWContact |
| PRO 2 | NTc.Cm32 | TYR 268 | 6.51x51 | VdWContact |
| PRO 2 | NTc.Cm32 | LEU 297 | 7.35x34 | Hydrophobic |
| PRO 2 | NTc.Cm32 | GLN 301 | 7.39x38 | VdWContact |
| ASP 3 | NTc.Cm31 | LEU 209 | 5.35x36 | VdWContact |
| ALA 4 | NTc.Cm30 | ARG 197 | 45.51x51 | HBAcceptor |
| ALA 4 | NTc.Cm30 | ARG 197 | 45.51x51 | Hydrophobic |
| ALA 4 | NTc.Cm30 | ARG 197 | 45.51x51 | VdWContact |
| ILE 5 | NTc.Cm29 | ASP 275 | 6.58x58 | VdWContact |
| ILE 5 | NTc.Cm29 | GLU 290 | 7.28x27 | VdWContact |
| ILE 5 | NTc.Cm29 | LEU 293 | 7.31x30 | Hydrophobic |
| ILE 5 | NTc.Cm29 | PHE 294 | 7.32x31 | Hydrophobic |
| ILE 5 | NTc.Cm29 | LEU 297 | 7.35x34 | Hydrophobic |
| ILE 5 | NTc.Cm29 | LEU 297 | 7.35x34 | VdWContact |
| ASN 6 | NTc.Cm28 | LYS 40 | - | VdWContact |
| ASN 6 | NTc.Cm28 | ASN 108 | - | VdWContact |
| ASN 6 | NTc.Cm28 | PHE 294 | 7.32x31 | Hydrophobic |
| ASN 6 | NTc.Cm28 | PHE 294 | 7.32x31 | VdWContact |
| ALA 7 | NTc.Cm27 | ARG 197 | 45.51x51 | VdWContact |
| THR 10 | NTc.Cm24 | THR 31 | - | Hydrophobic |
| CYS 11 | NTc.Cm23 | THR 31 | - | VdWContact |
| CYS 11 | NTc.Cm23 | VAL 32 | - | HBAcceptor |
| CYS 11 | NTc.Cm23 | VAL 32 | - | VdWContact |
| TYR 13 | NTc.Cm21 | ASP 30 | - | HBDonor |
| TYR 13 | NTc.Cm21 | ASP 30 | - | Hydrophobic |
| TYR 13 | NTc.Cm21 | ASP 30 | - | VdWContact |
| TYR 13 | NTc.Cm21 | VAL 32 | - | Hydrophobic |
| TYR 13 | NTc.Cm21 | PHE 285 | - | Hydrophobic |
| TYR 13 | NTc.Cm21 | PHE 285 | - | VdWContact |
| ASN 14 | NTc.Cm20 | ASP 30 | - | HBDonor |
| ASN 14 | NTc.Cm20 | ASP 30 | - | Hydrophobic |
| ASN 14 | NTc.Cm20 | ASP 30 | - | VdWContact |
| PHE 15 | NTc.Cm19 | ILE 27 | - | VdWContact |
| THR 16 | NTc.Cm18 | ILE 27 | - | VdWContact |
| ASN 17 | NTc.Cm17 | ILE 27 | - | Hydrophobic |
| ASN 17 | NTc.Cm17 | ILE 27 | - | VdWContact |
| ARG 18 | NTc.Cm16 | SER 23 | - | HBDonor |
| ARG 18 | NTc.Cm16 | SER 23 | - | VdWContact |
| ARG 18 | NTc.Cm16 | ASP 25 | - | Cationic |
| ARG 18 | NTc.Cm16 | ASP 25 | - | HBDonor |
| ARG 18 | NTc.Cm16 | ASP 25 | - | Hydrophobic |
| ARG 18 | NTc.Cm16 | ASP 25 | - | VdWContact |
| ARG 18 | NTc.Cm16 | ILE 27 | - | Hydrophobic |
| ARG 18 | NTc.Cm16 | ILE 27 | - | VdWContact |
| ARG 24 | NTc.Cm10 | TRP 19 | - | VdWContact |
| ARG 30 | NTc.Cm4 | GLU 202 | - | Cationic |
| THR 32 | NTc.Cm2 | GLU 202 | - | Hydrophobic |
| THR 32 | NTc.Cm2 | ILE 205 | 5.31x32 | Hydrophobic |
| THR 32 | NTc.Cm2 | ILE 205 | 5.31x32 | VdWContact |
| SER 34 | CX.1 | LYS 206 | 5.32x33 | VdWContact |
| SER 34 | CX.1 | LEU 209 | 5.35x36 | VdWContact |
| LYS 35 | CX.5 | ASP 275 | 6.58x58 | Cationic |
| LYS 35 | CX.5 | ASP 275 | 6.58x58 | HBDonor |
| LYS 35 | CX.5 | ASP 275 | 6.58x58 | VdWContact |
| LYS 35 | CX.5 | ILE 279 | 6.62x62 | Hydrophobic |
| LYS 35 | CX.5 | HIS 281 | 6.64x64 | VdWContact |
| LYS 35 | CX.5 | GLU 290 | 7.28x27 | Cationic |
| LYS 35 | CX.5 | GLU 290 | 7.28x27 | HBDonor |
| LYS 35 | CX.5 | GLU 290 | 7.28x27 | VdWContact |
| CYS 36 | cxb1.1 | LYS 206 | 5.32x33 | HBAcceptor |
| CYS 36 | cxb1.1 | LYS 206 | 5.32x33 | VdWContact |
| PRO 37 | cxb1.2 | HIS 281 | 6.64x64 | Hydrophobic |
| PRO 37 | cxb1.2 | HIS 281 | 6.64x64 | VdWContact |
| VAL 47 | B1.1 | ILE 17 | - | Hydrophobic |
| VAL 47 | B1.1 | ILE 17 | - | VdWContact |
| ALA 48 | B1.2 | PHE 14 | - | VdWContact |
| LYS 49 | B1.3 | PHE 14 | - | Hydrophobic |
| LYS 49 | B1.3 | ILE 17 | - | Hydrophobic |
| LYS 49 | B1.3 | ILE 17 | - | VdWContact |
| ILE 51 | B1.5 | VAL 29 | - | Hydrophobic |
| ILE 51 | B1.5 | VAL 29 | - | VdWContact |
| CYS 52 | B1.6 | VAL 29 | - | Hydrophobic |
| CYS 52 | B1.6 | VAL 29 | - | VdWContact |
| CYS 52 | B1.6 | THR 31 | - | VdWContact |
