Predicted complex interactions
CCL22_HUMAN + ACKR3
SUMMARY
- Chemokine
- CCL22_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR3 View partner entry
- Partner description
- UniProt: P25106; Gene: ackr3_human; Family: Chemokine
- Interactions detected
- 92
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm35 | GLN 301 | 7.39x38 | HBDonor |
| GLY 1 | NTc.Cm35 | GLN 301 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm34 | HIS 121 | 3.29x29 | Hydrophobic |
| PRO 2 | NTc.Cm34 | HIS 121 | 3.29x29 | VdWContact |
| PRO 2 | NTc.Cm34 | PHE 124 | 3.32x32 | Hydrophobic |
| TYR 3 | NTc.Cm33 | SER 125 | 3.33x33 | HBAcceptor |
| TYR 3 | NTc.Cm33 | PHE 129 | 3.37x37 | Hydrophobic |
| TYR 3 | NTc.Cm33 | PHE 129 | 3.37x37 | VdWContact |
| TYR 3 | NTc.Cm33 | ASP 179 | 4.60x61 | Hydrophobic |
| TYR 3 | NTc.Cm33 | MET 212 | 5.38x39 | Hydrophobic |
| TYR 3 | NTc.Cm33 | GLU 213 | 5.39x40 | Hydrophobic |
| TYR 3 | NTc.Cm33 | GLU 213 | 5.39x40 | VdWContact |
| TYR 3 | NTc.Cm33 | TYR 268 | 6.51x51 | VdWContact |
| TYR 3 | NTc.Cm33 | VAL 272 | 6.55x55 | Hydrophobic |
| GLY 4 | NTc.Cm32 | GLU 213 | 5.39x40 | HBDonor |
| GLY 4 | NTc.Cm32 | GLU 213 | 5.39x40 | VdWContact |
| GLY 4 | NTc.Cm32 | ASP 275 | 6.58x58 | VdWContact |
| GLY 4 | NTc.Cm32 | LEU 297 | 7.35x34 | VdWContact |
| ASN 6 | NTc.Cm30 | LEU 209 | 5.35x36 | Hydrophobic |
| ASN 6 | NTc.Cm30 | LEU 209 | 5.35x36 | VdWContact |
| MET 7 | NTc.Cm29 | ARG 197 | 45.51x51 | HBAcceptor |
| MET 7 | NTc.Cm29 | ARG 197 | 45.51x51 | VdWContact |
| MET 7 | NTc.Cm29 | LEU 293 | 7.31x30 | Hydrophobic |
| MET 7 | NTc.Cm29 | PHE 294 | 7.32x31 | Hydrophobic |
| MET 7 | NTc.Cm29 | PHE 294 | 7.32x31 | VdWContact |
| MET 7 | NTc.Cm29 | LEU 297 | 7.35x34 | Hydrophobic |
| MET 7 | NTc.Cm29 | HIS 298 | 7.36x35 | Hydrophobic |
| GLU 8 | NTc.Cm28 | ARG 197 | 45.51x51 | VdWContact |
| VAL 11 | NTc.Cm25 | VAL 29 | - | Hydrophobic |
| VAL 11 | NTc.Cm25 | THR 31 | - | Hydrophobic |
| VAL 11 | NTc.Cm25 | THR 31 | - | VdWContact |
| ARG 14 | NTc.Cm22 | ASP 30 | - | Cationic |
| ARG 14 | NTc.Cm22 | ASP 30 | - | Hydrophobic |
| ARG 14 | NTc.Cm22 | VAL 32 | - | Hydrophobic |
| ARG 14 | NTc.Cm22 | PHE 285 | - | HBDonor |
| ARG 14 | NTc.Cm22 | PHE 285 | - | VdWContact |
| ASP 15 | NTc.Cm21 | ILE 27 | - | Hydrophobic |
| ASP 15 | NTc.Cm21 | ILE 27 | - | VdWContact |
| TYR 16 | NTc.Cm20 | ILE 27 | - | VdWContact |
| VAL 17 | NTc.Cm19 | ILE 27 | - | Hydrophobic |
| VAL 17 | NTc.Cm19 | ILE 27 | - | VdWContact |
| ARG 18 | NTc.Cm18 | ILE 27 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | TRP 19 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | PRO 20 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | CYS 21 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | CYS 21 | - | VdWContact |
| TYR 19 | NTc.Cm17 | ASP 25 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | ASP 25 | - | VdWContact |
| TYR 19 | NTc.Cm17 | CYS 26 | - | VdWContact |
| LEU 21 | NTc.Cm15 | TRP 19 | - | Hydrophobic |
| LEU 21 | NTc.Cm15 | TRP 19 | - | VdWContact |
| PRO 22 | NTc.Cm14 | PRO 20 | - | Hydrophobic |
| PRO 22 | NTc.Cm14 | PRO 20 | - | VdWContact |
| ARG 24 | NTc.Cm12 | PHE 14 | - | VdWContact |
| ARG 24 | NTc.Cm12 | ILE 17 | - | Hydrophobic |
| ARG 24 | NTc.Cm12 | ILE 17 | - | VdWContact |
| VAL 25 | NTc.Cm11 | ILE 17 | - | Hydrophobic |
| VAL 25 | NTc.Cm11 | ILE 17 | - | VdWContact |
| VAL 25 | NTc.Cm11 | TRP 19 | - | Hydrophobic |
| VAL 25 | NTc.Cm11 | TRP 19 | - | VdWContact |
| ASP 34 | NTc.Cm2 | ILE 205 | 5.31x32 | Hydrophobic |
| ASP 34 | NTc.Cm2 | ILE 205 | 5.31x32 | VdWContact |
| ASP 34 | NTc.Cm2 | LYS 206 | 5.32x33 | VdWContact |
| SER 35 | NTc.Cm1 | LYS 206 | 5.32x33 | VdWContact |
| CYS 36 | CX.1 | LYS 206 | 5.32x33 | VdWContact |
| PRO 37 | CX.5 | HIS 281 | 6.64x64 | Hydrophobic |
| PRO 37 | CX.5 | HIS 281 | 6.64x64 | VdWContact |
| PRO 37 | CX.5 | PHE 285 | - | Hydrophobic |
| VAL 42 | cxb1.7 | VAL 29 | - | Hydrophobic |
| VAL 42 | cxb1.7 | VAL 29 | - | VdWContact |
| THR 45 | cxb1.11 | TRP 19 | - | Hydrophobic |
| THR 45 | cxb1.11 | TRP 19 | - | VdWContact |
| PHE 46 | cxb1.14 | PHE 14 | - | Hydrophobic |
| PHE 46 | cxb1.14 | PHE 14 | - | PiStacking |
| ARG 47 | cxb1.15 | PHE 14 | - | HBDonor |
| ARG 47 | cxb1.15 | PHE 14 | - | VdWContact |
| ARG 47 | cxb1.15 | SER 15 | - | VdWContact |
| LYS 49 | B1.1 | TRP 19 | - | Hydrophobic |
| LYS 49 | B1.1 | CYS 21 | - | Cationic |
| LYS 49 | B1.1 | CYS 26 | - | Cationic |
| GLU 50 | B1.2 | VAL 29 | - | HBAcceptor |
| GLU 50 | B1.2 | VAL 29 | - | Hydrophobic |
| GLU 50 | B1.2 | VAL 29 | - | VdWContact |
| GLU 50 | B1.2 | THR 31 | - | Hydrophobic |
| GLU 50 | B1.2 | THR 31 | - | VdWContact |
| ILE 51 | B1.3 | TRP 19 | - | Hydrophobic |
| ILE 51 | B1.3 | TRP 19 | - | VdWContact |
| ILE 51 | B1.3 | ILE 27 | - | VdWContact |
| ILE 51 | B1.3 | VAL 28 | - | VdWContact |
| ILE 51 | B1.3 | VAL 29 | - | VdWContact |
| CYS 52 | B1.4 | VAL 29 | - | Hydrophobic |
| CYS 52 | B1.4 | VAL 29 | - | VdWContact |
