Interactions for 1F2L (chain C)


Structure details


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Chemokine diagram


Q A S C G K R A 30s-loop R Q H R 40s-loop D P K E 50s-loopN-term M A P I S L S W L L R L A T F C H L T V L L A G Q H H G V T K C N I T C S K M T S K I P V A L N-termC-term A A A L T R N G G T F E K Q I G E V K P R T T P A A G G M D E S V V L E P E A T G E S S S L E P T P S S Q E A Q R A L G T S P E L P T G V T G S S G T R L P P T P K A Q D G G P V G T E L F R V P P V S T A A T W Q S S A P H Q P G P S L W A E A K T S E A P S T Q D P S T Q A S T A S S P A P E E N A P S E G Q R V W G Q G Q S P R P E N S L E R E E M G P V P A H T D A F Q D W G P G S M A H V S V V P V S S E G T P S R E P V A S G S W T P K A E E P I H A T M D P Q R L G V L I T P V P D A Q A A T R R Q A V G L L A F L G L L F C L G V A M F T Y Q S L Q G C P R K M A G E M A E G L R Y I P R S C G S N S Y V L V P V C-term N Q Q Y H I L I I L E T A C F L Q W V K D A M Q H L D R Q
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Interactions found in structure


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Chemokine Residue Generic number Segment Partner Residue Partner Interaction Type
Lys 7 62 N-term LYS 14 FRACTALKINE (B) Hydrophobic
Lys 7 62 N-term LYS 14 FRACTALKINE (B) VdWContact
Cys 8 63 CX SER 13 FRACTALKINE (B) VdWContact
Cys 8 63 CX LYS 14 FRACTALKINE (B) HBAcceptor
Cys 8 63 CX LYS 14 FRACTALKINE (B) VdWContact
Asn 9 64 CX CYS 12 FRACTALKINE (B) VdWContact
Asn 9 64 CX SER 13 FRACTALKINE (B) HBAcceptor
Asn 9 64 CX SER 13 FRACTALKINE (B) VdWContact
Ile 10 65 CX ILE 10 FRACTALKINE (B) Hydrophobic
Ile 10 65 CX ILE 10 FRACTALKINE (B) VdWContact
Ile 10 65 CX LEU 48 FRACTALKINE (B) Hydrophobic
Ile 10 65 CX THR 11 FRACTALKINE (B) VdWContact
Ile 10 65 CX ILE 40 FRACTALKINE (B) Hydrophobic
Ile 10 65 CX CYS 50 FRACTALKINE (B) VdWContact
Thr 11 66 CX ILE 10 FRACTALKINE (B) VdWContact
Thr 11 66 CX THR 11 FRACTALKINE (B) Hydrophobic
Thr 11 66 CX THR 11 FRACTALKINE (B) HBAcceptor
Thr 11 66 CX THR 11 FRACTALKINE (B) HBDonor
Thr 11 66 CX THR 11 FRACTALKINE (B) VdWContact
Cys 12 67 CX ILE 10 FRACTALKINE (B) Hydrophobic
Cys 12 67 CX ASN 9 FRACTALKINE (B) VdWContact
Ser 13 68 N-loop ASN 9 FRACTALKINE (B) HBDonor
Ser 13 68 N-loop ASN 9 FRACTALKINE (B) VdWContact
Lys 14 69 N-loop ASN 9 FRACTALKINE (B) Hydrophobic
Lys 14 69 N-loop ASN 9 FRACTALKINE (B) HBDonor
Lys 14 69 N-loop ASN 9 FRACTALKINE (B) VdWContact
Leu 23 82 N-loop LEU 72 FRACTALKINE (D) Hydrophobic
Ile 25 84 B1 HIS 46 FRACTALKINE (B) Hydrophobic
His 26 85 B1 HIS 46 FRACTALKINE (B) Hydrophobic
His 26 85 B1 HIS 46 FRACTALKINE (B) VdWContact
Gln 28 87 B1 LEU 48 FRACTALKINE (B) HBAcceptor
Gln 28 87 B1 LEU 48 FRACTALKINE (B) HBDonor
Gln 28 87 B1 LEU 48 FRACTALKINE (B) VdWContact
Ile 40 102 B2 LEU 48 FRACTALKINE (B) Hydrophobic
Thr 43 105 B2 LEU 72 FRACTALKINE (D) Hydrophobic
Arg 44 106 40s-loop HIS 46 FRACTALKINE (A) VdWContact
His 46 113 40s-loop GLN 28 FRACTALKINE (B) VdWContact
His 46 113 40s-loop HIS 46 FRACTALKINE (A) Hydrophobic
His 46 113 40s-loop ARG 44 FRACTALKINE (A) Hydrophobic
Arg 47 114 40s-loop ALA 69 FRACTALKINE (D) HBDonor
Arg 47 114 40s-loop ALA 69 FRACTALKINE (D) VdWContact
Leu 48 115 B3 GLN 28 FRACTALKINE (B) Hydrophobic
Leu 48 115 B3 GLN 28 FRACTALKINE (B) VdWContact
Leu 48 115 B3 ILE 10 FRACTALKINE (B) Hydrophobic
Leu 48 115 B3 LEU 48 FRACTALKINE (B) Hydrophobic
Leu 48 115 B3 ILE 40 FRACTALKINE (B) Hydrophobic
Phe 49 116 B3 LEU 72 FRACTALKINE (D) Hydrophobic
Phe 49 116 B3 LEU 72 FRACTALKINE (D) VdWContact
Cys 50 117 B3 ASN 9 FRACTALKINE (B) VdWContact

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