Interactions for 1F2L (chain D)


Structure details


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Chemokine diagram


Q A S C G K R A 30s-loop R Q H R 40s-loop D P K E 50s-loopN-term M A P I S L S W L L R L A T F C H L T V L L A G Q H H G V T K C N I T C S K M T S K I P V A L N-termC-term A A A L T R N G G T F E K Q I G E V K P R T T P A A G G M D E S V V L E P E A T G E S S S L E P T P S S Q E A Q R A L G T S P E L P T G V T G S S G T R L P P T P K A Q D G G P V G T E L F R V P P V S T A A T W Q S S A P H Q P G P S L W A E A K T S E A P S T Q D P S T Q A S T A S S P A P E E N A P S E G Q R V W G Q G Q S P R P E N S L E R E E M G P V P A H T D A F Q D W G P G S M A H V S V V P V S S E G T P S R E P V A S G S W T P K A E E P I H A T M D P Q R L G V L I T P V P D A Q A A T R R Q A V G L L A F L G L L F C L G V A M F T Y Q S L Q G C P R K M A G E M A E G L R Y I P R S C G S N S Y V L V P V C-term N Q Q Y H I L I I L E T A C F L Q W V K D A M Q H L D R Q
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Interactions found in structure


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Chemokine Residue Generic number Segment Partner Residue Partner Interaction Type
Lys 7 62 N-term LYS 14 FRACTALKINE (A) Hydrophobic
Lys 7 62 N-term LYS 14 FRACTALKINE (A) VdWContact
Asn 9 64 CX LYS 14 FRACTALKINE (A) Hydrophobic
Asn 9 64 CX LYS 14 FRACTALKINE (A) VdWContact
Ile 10 65 CX CYS 12 FRACTALKINE (A) Hydrophobic
Ile 10 65 CX CYS 12 FRACTALKINE (A) VdWContact
Ile 10 65 CX ILE 10 FRACTALKINE (A) Hydrophobic
Ile 10 65 CX ILE 10 FRACTALKINE (A) VdWContact
Ile 10 65 CX LEU 48 FRACTALKINE (A) Hydrophobic
Thr 11 66 CX THR 11 FRACTALKINE (A) HBAcceptor
Thr 11 66 CX THR 11 FRACTALKINE (A) HBDonor
Thr 11 66 CX THR 11 FRACTALKINE (A) VdWContact
Cys 12 67 CX ASN 9 FRACTALKINE (A) VdWContact
Ser 13 68 N-loop CYS 8 FRACTALKINE (A) VdWContact
Ser 13 68 N-loop ASN 9 FRACTALKINE (A) HBDonor
Ser 13 68 N-loop ASN 9 FRACTALKINE (A) VdWContact
Lys 14 69 N-loop CYS 8 FRACTALKINE (A) HBDonor
Lys 14 69 N-loop CYS 8 FRACTALKINE (A) VdWContact
Lys 14 69 N-loop LYS 7 FRACTALKINE (A) Hydrophobic
Lys 14 69 N-loop LYS 7 FRACTALKINE (A) VdWContact
Lys 14 69 N-loop ASN 9 FRACTALKINE (A) HBAcceptor
Lys 14 69 N-loop ASN 9 FRACTALKINE (A) VdWContact
Gln 28 87 B1 HIS 46 FRACTALKINE (A) HBDonor
Gln 28 87 B1 HIS 46 FRACTALKINE (A) VdWContact
Ile 40 102 B2 ILE 10 FRACTALKINE (A) Hydrophobic
Ile 40 102 B2 LEU 48 FRACTALKINE (A) Hydrophobic
His 46 113 40s-loop HIS 26 FRACTALKINE (A) Hydrophobic
His 46 113 40s-loop HIS 26 FRACTALKINE (A) VdWContact
Arg 47 114 40s-loop GLN 28 FRACTALKINE (A) VdWContact
Leu 48 115 B3 GLN 28 FRACTALKINE (A) HBAcceptor
Leu 48 115 B3 GLN 28 FRACTALKINE (A) HBDonor
Leu 48 115 B3 GLN 28 FRACTALKINE (A) VdWContact
Leu 48 115 B3 LEU 48 FRACTALKINE (A) Hydrophobic
Leu 48 115 B3 HIS 26 FRACTALKINE (A) Hydrophobic
Leu 48 115 B3 ILE 40 FRACTALKINE (A) Hydrophobic
Cys 50 117 B3 ILE 10 FRACTALKINE (A) VdWContact
Cys 50 117 B3 ASN 9 FRACTALKINE (A) HBAcceptor
Cys 50 117 B3 ASN 9 FRACTALKINE (A) HBDonor
Cys 50 117 B3 ASN 9 FRACTALKINE (A) VdWContact
Ala 69 136 C-term ARG 47 FRACTALKINE (C) HBAcceptor
Ala 69 136 C-term ARG 47 FRACTALKINE (C) VdWContact
Leu 72 139 C-term PHE 49 FRACTALKINE (C) Hydrophobic
Leu 72 139 C-term PHE 49 FRACTALKINE (C) VdWContact
Leu 72 139 C-term LEU 23 FRACTALKINE (C) Hydrophobic
Leu 72 139 C-term THR 43 FRACTALKINE (C) Hydrophobic

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