Interactions for 1ILP (chain A)


Structure details


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Chemokine diagram


E S G P H C A N T E 30s-loop S D G R 40s-loop D P K E 50s-loopN-term M T S K L A V A L L A A F L I S A A L C E G A V L P R S A K E L R C Q C I K T Y S K P F H P K F N-termC-term A E N S C-term I V R L E K I I I V K L L C L E N W V Q R V V E K F L K R
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Interactions found in structure


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Chemokine Residue Generic number Segment Partner Residue Partner Interaction Type
Gln 8 66 CX PRO 17 C-X-C chemokine receptor type 1 (C) Hydrophobic
Gln 8 66 CX PRO 17 C-X-C chemokine receptor type 1 (C) HBDonor
Gln 8 66 CX PRO 17 C-X-C chemokine receptor type 1 (C) VdWContact
Ile 10 68 N-loop SER 16 C-X-C chemokine receptor type 1 (C) VdWContact
Lys 11 69 N-loop TYR 15 C-X-C chemokine receptor type 1 (C) Hydrophobic
Lys 11 69 N-loop ASP 14 C-X-C chemokine receptor type 1 (C) Hydrophobic
Lys 11 69 N-loop ASP 14 C-X-C chemokine receptor type 1 (C) Cationic
Lys 11 69 N-loop ASP 14 C-X-C chemokine receptor type 1 (C) VdWContact
Tyr 13 71 N-loop PRO 10 C-X-C chemokine receptor type 1 (C) Hydrophobic
Tyr 13 71 N-loop PRO 10 C-X-C chemokine receptor type 1 (C) VdWContact
Tyr 13 71 N-loop ALA 11 C-X-C chemokine receptor type 1 (C) HBAcceptor
Tyr 13 71 N-loop ALA 11 C-X-C chemokine receptor type 1 (C) VdWContact
Tyr 13 71 N-loop TYR 15 C-X-C chemokine receptor type 1 (C) Hydrophobic
Tyr 13 71 N-loop TYR 15 C-X-C chemokine receptor type 1 (C) VdWContact
Tyr 13 71 N-loop ASP 12 C-X-C chemokine receptor type 1 (C) Hydrophobic
Tyr 13 71 N-loop ASP 12 C-X-C chemokine receptor type 1 (C) VdWContact
Lys 15 73 N-loop PRO 9 C-X-C chemokine receptor type 1 (C) HBDonor
Lys 15 73 N-loop PRO 9 C-X-C chemokine receptor type 1 (C) VdWContact
Lys 15 73 N-loop MET 8 C-X-C chemokine receptor type 1 (C) VdWContact
Phe 17 75 N-loop PRO 10 C-X-C chemokine receptor type 1 (C) Hydrophobic
His 18 76 N-loop ASP 6 C-X-C chemokine receptor type 1 (C) Hydrophobic
His 18 76 N-loop ASP 6 C-X-C chemokine receptor type 1 (C) VdWContact
Lys 20 81 N-loop ASP 5 C-X-C chemokine receptor type 1 (C) VdWContact
Lys 20 81 N-loop ASP 6 C-X-C chemokine receptor type 1 (C) HBDonor
Lys 20 81 N-loop ASP 6 C-X-C chemokine receptor type 1 (C) Cationic
Lys 20 81 N-loop ASP 6 C-X-C chemokine receptor type 1 (C) VdWContact
Lys 20 81 N-loop PHE 4 C-X-C chemokine receptor type 1 (C) Hydrophobic
Phe 21 82 N-loop PHE 4 C-X-C chemokine receptor type 1 (C) Hydrophobic
Phe 21 82 N-loop PRO 9 C-X-C chemokine receptor type 1 (C) Hydrophobic
Lys 23 84 B1 GLU 29 Interleukin-8 (precursor) (B) HBAcceptor
Lys 23 84 B1 GLU 29 Interleukin-8 (precursor) (B) VdWContact
Glu 24 85 B1 ARG 26 Interleukin-8 (precursor) (B) Anionic
Glu 24 85 B1 ILE 28 Interleukin-8 (precursor) (B) Hydrophobic
Glu 24 85 B1 ILE 28 Interleukin-8 (precursor) (B) VdWContact
Leu 25 86 B1 VAL 27 Interleukin-8 (precursor) (B) Hydrophobic
Leu 25 86 B1 VAL 27 Interleukin-8 (precursor) (B) HBAcceptor
Leu 25 86 B1 VAL 27 Interleukin-8 (precursor) (B) HBDonor
Leu 25 86 B1 VAL 27 Interleukin-8 (precursor) (B) VdWContact
Arg 26 87 B1 ARG 26 Interleukin-8 (precursor) (B) Hydrophobic
Arg 26 87 B1 ARG 26 Interleukin-8 (precursor) (B) VdWContact
Arg 26 87 B1 GLU 24 Interleukin-8 (precursor) (B) Cationic
Val 27 88 B1 LEU 25 Interleukin-8 (precursor) (B) Hydrophobic
Val 27 88 B1 LEU 25 Interleukin-8 (precursor) (B) HBAcceptor
Val 27 88 B1 LEU 25 Interleukin-8 (precursor) (B) HBDonor
Val 27 88 B1 LEU 25 Interleukin-8 (precursor) (B) VdWContact
Val 27 88 B1 PHE 65 Interleukin-8 (precursor) (B) Hydrophobic
Ile 28 89 B1 GLU 24 Interleukin-8 (precursor) (B) Hydrophobic
Ile 28 89 B1 GLU 24 Interleukin-8 (precursor) (B) VdWContact
Glu 29 90 30s-loop LYS 23 Interleukin-8 (precursor) (B) HBDonor
Glu 29 90 30s-loop LYS 23 Interleukin-8 (precursor) (B) VdWContact
Glu 29 90 30s-loop ARG 68 Interleukin-8 (precursor) (B) Anionic
Glu 29 90 30s-loop ARG 68 Interleukin-8 (precursor) (B) VdWContact
Glu 29 90 30s-loop PHE 65 Interleukin-8 (precursor) (B) Hydrophobic
Glu 29 90 30s-loop PHE 65 Interleukin-8 (precursor) (B) VdWContact
Glu 29 90 30s-loop ALA 69 Interleukin-8 (precursor) (B) Hydrophobic
Thr 37 99 30s-loop ALA 69 Interleukin-8 (precursor) (B) Hydrophobic
Thr 37 99 30s-loop ALA 69 Interleukin-8 (precursor) (B) HBDonor
Thr 37 99 30s-loop ALA 69 Interleukin-8 (precursor) (B) VdWContact
Ile 40 102 B2 PRO 17 C-X-C chemokine receptor type 1 (C) Hydrophobic
Leu 43 105 B2 PRO 9 C-X-C chemokine receptor type 1 (C) Hydrophobic
Leu 43 105 B2 PRO 10 C-X-C chemokine receptor type 1 (C) Hydrophobic
Arg 47 114 40s-loop GLU 13 C-X-C chemokine receptor type 1 (C) VdWContact
Arg 47 114 40s-loop TYR 15 C-X-C chemokine receptor type 1 (C) HBDonor
Arg 47 114 40s-loop TYR 15 C-X-C chemokine receptor type 1 (C) VdWContact
Glu 48 115 B3 TYR 15 C-X-C chemokine receptor type 1 (C) VdWContact
Leu 49 116 B3 PRO 10 C-X-C chemokine receptor type 1 (C) Hydrophobic
Leu 49 116 B3 PRO 10 C-X-C chemokine receptor type 1 (C) VdWContact
Leu 49 116 B3 TYR 15 C-X-C chemokine receptor type 1 (C) Hydrophobic
Cys 50 117 B3 PRO 17 C-X-C chemokine receptor type 1 (C) VdWContact
Phe 65 132 Helix GLU 29 Interleukin-8 (precursor) (B) Hydrophobic
Phe 65 132 Helix GLU 29 Interleukin-8 (precursor) (B) VdWContact
Phe 65 132 Helix VAL 27 Interleukin-8 (precursor) (B) Hydrophobic
Arg 68 135 Helix GLU 29 Interleukin-8 (precursor) (B) Cationic
Arg 68 135 Helix GLU 29 Interleukin-8 (precursor) (B) VdWContact
Ala 69 136 C-term GLU 29 Interleukin-8 (precursor) (B) Hydrophobic
Ala 69 136 C-term THR 37 Interleukin-8 (precursor) (B) Hydrophobic
Ala 69 136 C-term THR 37 Interleukin-8 (precursor) (B) HBAcceptor
Ala 69 136 C-term THR 37 Interleukin-8 (precursor) (B) VdWContact

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