Interactions for 1ILP (chain A)
Structure details
- PDB ID: 1ILP open_in_new
- Protein: CXCL8_HUMAN
- Organism: Homo sapiens
- UniProt ID: P10145 open_in_new
- Method: Solution nmr
- Resolution: 0.0 Å
- Date: Dec. 23, 1998
- Reference: 10.1016/S0969-2126(99)80022-7 open_in_new
- State: dimer
Chemokine diagram
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Interactions found in structure
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Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
---|---|---|---|---|---|
Gln 8 | 66 | CX | PRO 17 | C-X-C chemokine receptor type 1 (C) | Hydrophobic |
Gln 8 | 66 | CX | PRO 17 | C-X-C chemokine receptor type 1 (C) | HBDonor |
Gln 8 | 66 | CX | PRO 17 | C-X-C chemokine receptor type 1 (C) | VdWContact |
Ile 10 | 68 | N-loop | SER 16 | C-X-C chemokine receptor type 1 (C) | VdWContact |
Lys 11 | 69 | N-loop | TYR 15 | C-X-C chemokine receptor type 1 (C) | Hydrophobic |
Lys 11 | 69 | N-loop | ASP 14 | C-X-C chemokine receptor type 1 (C) | Hydrophobic |
Lys 11 | 69 | N-loop | ASP 14 | C-X-C chemokine receptor type 1 (C) | Cationic |
Lys 11 | 69 | N-loop | ASP 14 | C-X-C chemokine receptor type 1 (C) | VdWContact |
Tyr 13 | 71 | N-loop | PRO 10 | C-X-C chemokine receptor type 1 (C) | Hydrophobic |
Tyr 13 | 71 | N-loop | PRO 10 | C-X-C chemokine receptor type 1 (C) | VdWContact |
Tyr 13 | 71 | N-loop | ALA 11 | C-X-C chemokine receptor type 1 (C) | HBAcceptor |
Tyr 13 | 71 | N-loop | ALA 11 | C-X-C chemokine receptor type 1 (C) | VdWContact |
Tyr 13 | 71 | N-loop | TYR 15 | C-X-C chemokine receptor type 1 (C) | Hydrophobic |
Tyr 13 | 71 | N-loop | TYR 15 | C-X-C chemokine receptor type 1 (C) | VdWContact |
Tyr 13 | 71 | N-loop | ASP 12 | C-X-C chemokine receptor type 1 (C) | Hydrophobic |
Tyr 13 | 71 | N-loop | ASP 12 | C-X-C chemokine receptor type 1 (C) | VdWContact |
Lys 15 | 73 | N-loop | PRO 9 | C-X-C chemokine receptor type 1 (C) | HBDonor |
Lys 15 | 73 | N-loop | PRO 9 | C-X-C chemokine receptor type 1 (C) | VdWContact |
Lys 15 | 73 | N-loop | MET 8 | C-X-C chemokine receptor type 1 (C) | VdWContact |
Phe 17 | 75 | N-loop | PRO 10 | C-X-C chemokine receptor type 1 (C) | Hydrophobic |
His 18 | 76 | N-loop | ASP 6 | C-X-C chemokine receptor type 1 (C) | Hydrophobic |
His 18 | 76 | N-loop | ASP 6 | C-X-C chemokine receptor type 1 (C) | VdWContact |
Lys 20 | 81 | N-loop | ASP 5 | C-X-C chemokine receptor type 1 (C) | VdWContact |
Lys 20 | 81 | N-loop | ASP 6 | C-X-C chemokine receptor type 1 (C) | HBDonor |
Lys 20 | 81 | N-loop | ASP 6 | C-X-C chemokine receptor type 1 (C) | Cationic |
Lys 20 | 81 | N-loop | ASP 6 | C-X-C chemokine receptor type 1 (C) | VdWContact |
Lys 20 | 81 | N-loop | PHE 4 | C-X-C chemokine receptor type 1 (C) | Hydrophobic |
Phe 21 | 82 | N-loop | PHE 4 | C-X-C chemokine receptor type 1 (C) | Hydrophobic |
Phe 21 | 82 | N-loop | PRO 9 | C-X-C chemokine receptor type 1 (C) | Hydrophobic |
Lys 23 | 84 | B1 | GLU 29 | Interleukin-8 (precursor) (B) | HBAcceptor |
Lys 23 | 84 | B1 | GLU 29 | Interleukin-8 (precursor) (B) | VdWContact |
Glu 24 | 85 | B1 | ARG 26 | Interleukin-8 (precursor) (B) | Anionic |
Glu 24 | 85 | B1 | ILE 28 | Interleukin-8 (precursor) (B) | Hydrophobic |
Glu 24 | 85 | B1 | ILE 28 | Interleukin-8 (precursor) (B) | VdWContact |
Leu 25 | 86 | B1 | VAL 27 | Interleukin-8 (precursor) (B) | Hydrophobic |
Leu 25 | 86 | B1 | VAL 27 | Interleukin-8 (precursor) (B) | HBAcceptor |
Leu 25 | 86 | B1 | VAL 27 | Interleukin-8 (precursor) (B) | HBDonor |
Leu 25 | 86 | B1 | VAL 27 | Interleukin-8 (precursor) (B) | VdWContact |
Arg 26 | 87 | B1 | ARG 26 | Interleukin-8 (precursor) (B) | Hydrophobic |
Arg 26 | 87 | B1 | ARG 26 | Interleukin-8 (precursor) (B) | VdWContact |
Arg 26 | 87 | B1 | GLU 24 | Interleukin-8 (precursor) (B) | Cationic |
Val 27 | 88 | B1 | LEU 25 | Interleukin-8 (precursor) (B) | Hydrophobic |
Val 27 | 88 | B1 | LEU 25 | Interleukin-8 (precursor) (B) | HBAcceptor |
Val 27 | 88 | B1 | LEU 25 | Interleukin-8 (precursor) (B) | HBDonor |
Val 27 | 88 | B1 | LEU 25 | Interleukin-8 (precursor) (B) | VdWContact |
Val 27 | 88 | B1 | PHE 65 | Interleukin-8 (precursor) (B) | Hydrophobic |
Ile 28 | 89 | B1 | GLU 24 | Interleukin-8 (precursor) (B) | Hydrophobic |
Ile 28 | 89 | B1 | GLU 24 | Interleukin-8 (precursor) (B) | VdWContact |
Glu 29 | 90 | 30s-loop | LYS 23 | Interleukin-8 (precursor) (B) | HBDonor |
Glu 29 | 90 | 30s-loop | LYS 23 | Interleukin-8 (precursor) (B) | VdWContact |
Glu 29 | 90 | 30s-loop | ARG 68 | Interleukin-8 (precursor) (B) | Anionic |
Glu 29 | 90 | 30s-loop | ARG 68 | Interleukin-8 (precursor) (B) | VdWContact |
Glu 29 | 90 | 30s-loop | PHE 65 | Interleukin-8 (precursor) (B) | Hydrophobic |
Glu 29 | 90 | 30s-loop | PHE 65 | Interleukin-8 (precursor) (B) | VdWContact |
Glu 29 | 90 | 30s-loop | ALA 69 | Interleukin-8 (precursor) (B) | Hydrophobic |
Thr 37 | 99 | 30s-loop | ALA 69 | Interleukin-8 (precursor) (B) | Hydrophobic |
Thr 37 | 99 | 30s-loop | ALA 69 | Interleukin-8 (precursor) (B) | HBDonor |
Thr 37 | 99 | 30s-loop | ALA 69 | Interleukin-8 (precursor) (B) | VdWContact |
Ile 40 | 102 | B2 | PRO 17 | C-X-C chemokine receptor type 1 (C) | Hydrophobic |
Leu 43 | 105 | B2 | PRO 9 | C-X-C chemokine receptor type 1 (C) | Hydrophobic |
Leu 43 | 105 | B2 | PRO 10 | C-X-C chemokine receptor type 1 (C) | Hydrophobic |
Arg 47 | 114 | 40s-loop | GLU 13 | C-X-C chemokine receptor type 1 (C) | VdWContact |
Arg 47 | 114 | 40s-loop | TYR 15 | C-X-C chemokine receptor type 1 (C) | HBDonor |
Arg 47 | 114 | 40s-loop | TYR 15 | C-X-C chemokine receptor type 1 (C) | VdWContact |
Glu 48 | 115 | B3 | TYR 15 | C-X-C chemokine receptor type 1 (C) | VdWContact |
Leu 49 | 116 | B3 | PRO 10 | C-X-C chemokine receptor type 1 (C) | Hydrophobic |
Leu 49 | 116 | B3 | PRO 10 | C-X-C chemokine receptor type 1 (C) | VdWContact |
Leu 49 | 116 | B3 | TYR 15 | C-X-C chemokine receptor type 1 (C) | Hydrophobic |
Cys 50 | 117 | B3 | PRO 17 | C-X-C chemokine receptor type 1 (C) | VdWContact |
Phe 65 | 132 | Helix | GLU 29 | Interleukin-8 (precursor) (B) | Hydrophobic |
Phe 65 | 132 | Helix | GLU 29 | Interleukin-8 (precursor) (B) | VdWContact |
Phe 65 | 132 | Helix | VAL 27 | Interleukin-8 (precursor) (B) | Hydrophobic |
Arg 68 | 135 | Helix | GLU 29 | Interleukin-8 (precursor) (B) | Cationic |
Arg 68 | 135 | Helix | GLU 29 | Interleukin-8 (precursor) (B) | VdWContact |
Ala 69 | 136 | C-term | GLU 29 | Interleukin-8 (precursor) (B) | Hydrophobic |
Ala 69 | 136 | C-term | THR 37 | Interleukin-8 (precursor) (B) | Hydrophobic |
Ala 69 | 136 | C-term | THR 37 | Interleukin-8 (precursor) (B) | HBAcceptor |
Ala 69 | 136 | C-term | THR 37 | Interleukin-8 (precursor) (B) | VdWContact |