Interactions for 1ILQ (chain A)
Structure details
- PDB ID: 1ILQ open_in_new
- Protein: CXCL8_HUMAN
- Organism: Homo sapiens
- UniProt ID: P10145 open_in_new
- Method: Solution nmr
- Resolution: 0.0 Å
- Date: Dec. 23, 1998
- Reference: 10.1016/S0969-2126(99)80022-7 open_in_new
- State: dimer
Chemokine diagram
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Interactions found in structure
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| Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
|---|---|---|---|---|---|
| Gln 8 | 66 | CX | PRO 17 | INTERLEUKIN-8 RECEPTOR A (C) | Hydrophobic |
| Gln 8 | 66 | CX | PRO 17 | INTERLEUKIN-8 RECEPTOR A (C) | HBDonor |
| Gln 8 | 66 | CX | PRO 17 | INTERLEUKIN-8 RECEPTOR A (C) | VdWContact |
| Ile 10 | 68 | N-loop | SER 16 | INTERLEUKIN-8 RECEPTOR A (C) | VdWContact |
| Lys 11 | 69 | N-loop | TYR 15 | INTERLEUKIN-8 RECEPTOR A (C) | Hydrophobic |
| Lys 11 | 69 | N-loop | ASP 14 | INTERLEUKIN-8 RECEPTOR A (C) | Hydrophobic |
| Lys 11 | 69 | N-loop | ASP 14 | INTERLEUKIN-8 RECEPTOR A (C) | VdWContact |
| Tyr 13 | 71 | N-loop | TYR 15 | INTERLEUKIN-8 RECEPTOR A (C) | Hydrophobic |
| Tyr 13 | 71 | N-loop | PRO 10 | INTERLEUKIN-8 RECEPTOR A (C) | Hydrophobic |
| Tyr 13 | 71 | N-loop | PRO 10 | INTERLEUKIN-8 RECEPTOR A (C) | VdWContact |
| Lys 15 | 73 | N-loop | ASP 12 | INTERLEUKIN-8 RECEPTOR A (C) | Cationic |
| Phe 17 | 75 | N-loop | PRO 9 | INTERLEUKIN-8 RECEPTOR A (C) | Hydrophobic |
| Lys 20 | 81 | N-loop | ASP 5 | INTERLEUKIN-8 RECEPTOR A (C) | HBDonor |
| Lys 20 | 81 | N-loop | ASP 5 | INTERLEUKIN-8 RECEPTOR A (C) | Cationic |
| Lys 20 | 81 | N-loop | ASP 5 | INTERLEUKIN-8 RECEPTOR A (C) | VdWContact |
| Phe 21 | 82 | N-loop | ASP 3 | INTERLEUKIN-8 RECEPTOR A (C) | VdWContact |
| Phe 21 | 82 | N-loop | ASP 5 | INTERLEUKIN-8 RECEPTOR A (C) | Hydrophobic |
| Phe 21 | 82 | N-loop | PRO 9 | INTERLEUKIN-8 RECEPTOR A (C) | Hydrophobic |
| Phe 21 | 82 | N-loop | PRO 9 | INTERLEUKIN-8 RECEPTOR A (C) | VdWContact |
| Lys 23 | 84 | B1 | GLU 29 | INTERLEUKIN-8 PRECURSOR (B) | HBAcceptor |
| Lys 23 | 84 | B1 | GLU 29 | INTERLEUKIN-8 PRECURSOR (B) | VdWContact |
| Glu 24 | 85 | B1 | ILE 28 | INTERLEUKIN-8 PRECURSOR (B) | Hydrophobic |
| Glu 24 | 85 | B1 | ILE 28 | INTERLEUKIN-8 PRECURSOR (B) | VdWContact |
| Glu 24 | 85 | B1 | ARG 26 | INTERLEUKIN-8 PRECURSOR (B) | Anionic |
| Leu 25 | 86 | B1 | VAL 27 | INTERLEUKIN-8 PRECURSOR (B) | Hydrophobic |
| Leu 25 | 86 | B1 | VAL 27 | INTERLEUKIN-8 PRECURSOR (B) | HBAcceptor |
| Leu 25 | 86 | B1 | VAL 27 | INTERLEUKIN-8 PRECURSOR (B) | HBDonor |
| Leu 25 | 86 | B1 | VAL 27 | INTERLEUKIN-8 PRECURSOR (B) | VdWContact |
| Arg 26 | 87 | B1 | ARG 26 | INTERLEUKIN-8 PRECURSOR (B) | Hydrophobic |
| Arg 26 | 87 | B1 | ARG 26 | INTERLEUKIN-8 PRECURSOR (B) | VdWContact |
| Arg 26 | 87 | B1 | GLU 24 | INTERLEUKIN-8 PRECURSOR (B) | Cationic |
| Val 27 | 88 | B1 | PHE 65 | INTERLEUKIN-8 PRECURSOR (B) | Hydrophobic |
| Val 27 | 88 | B1 | LEU 25 | INTERLEUKIN-8 PRECURSOR (B) | Hydrophobic |
| Val 27 | 88 | B1 | LEU 25 | INTERLEUKIN-8 PRECURSOR (B) | HBAcceptor |
| Val 27 | 88 | B1 | LEU 25 | INTERLEUKIN-8 PRECURSOR (B) | HBDonor |
| Val 27 | 88 | B1 | LEU 25 | INTERLEUKIN-8 PRECURSOR (B) | VdWContact |
| Ile 28 | 89 | B1 | GLU 24 | INTERLEUKIN-8 PRECURSOR (B) | Hydrophobic |
| Ile 28 | 89 | B1 | GLU 24 | INTERLEUKIN-8 PRECURSOR (B) | VdWContact |
| Glu 29 | 90 | 30s-loop | PHE 65 | INTERLEUKIN-8 PRECURSOR (B) | Hydrophobic |
| Glu 29 | 90 | 30s-loop | PHE 65 | INTERLEUKIN-8 PRECURSOR (B) | VdWContact |
| Glu 29 | 90 | 30s-loop | LYS 23 | INTERLEUKIN-8 PRECURSOR (B) | HBDonor |
| Glu 29 | 90 | 30s-loop | LYS 23 | INTERLEUKIN-8 PRECURSOR (B) | VdWContact |
| Glu 29 | 90 | 30s-loop | ARG 68 | INTERLEUKIN-8 PRECURSOR (B) | Anionic |
| Glu 29 | 90 | 30s-loop | ARG 68 | INTERLEUKIN-8 PRECURSOR (B) | VdWContact |
| Glu 29 | 90 | 30s-loop | ALA 69 | INTERLEUKIN-8 PRECURSOR (B) | Hydrophobic |
| Thr 37 | 99 | 30s-loop | ALA 69 | INTERLEUKIN-8 PRECURSOR (B) | Hydrophobic |
| Thr 37 | 99 | 30s-loop | ALA 69 | INTERLEUKIN-8 PRECURSOR (B) | HBDonor |
| Thr 37 | 99 | 30s-loop | ALA 69 | INTERLEUKIN-8 PRECURSOR (B) | VdWContact |
| Ile 40 | 102 | B2 | PRO 17 | INTERLEUKIN-8 RECEPTOR A (C) | Hydrophobic |
| Leu 43 | 105 | B2 | PRO 9 | INTERLEUKIN-8 RECEPTOR A (C) | Hydrophobic |
| Leu 43 | 105 | B2 | PRO 9 | INTERLEUKIN-8 RECEPTOR A (C) | VdWContact |
| Ser 44 | 106 | 40s-loop | ASP 3 | INTERLEUKIN-8 RECEPTOR A (C) | HBDonor |
| Ser 44 | 106 | 40s-loop | ASP 3 | INTERLEUKIN-8 RECEPTOR A (C) | VdWContact |
| Asp 45 | 112 | 40s-loop | ACE 0 | INTERLEUKIN-8 RECEPTOR A (C) | VdWContact |
| Asp 45 | 112 | 40s-loop | ASP 3 | INTERLEUKIN-8 RECEPTOR A (C) | Hydrophobic |
| Asp 45 | 112 | 40s-loop | ASP 3 | INTERLEUKIN-8 RECEPTOR A (C) | VdWContact |
| Arg 47 | 114 | 40s-loop | GLU 13 | INTERLEUKIN-8 RECEPTOR A (C) | Cationic |
| Glu 48 | 115 | B3 | PRO 17 | INTERLEUKIN-8 RECEPTOR A (C) | Hydrophobic |
| Leu 49 | 116 | B3 | TYR 15 | INTERLEUKIN-8 RECEPTOR A (C) | Hydrophobic |
| Leu 49 | 116 | B3 | PRO 10 | INTERLEUKIN-8 RECEPTOR A (C) | Hydrophobic |
| Leu 49 | 116 | B3 | PRO 10 | INTERLEUKIN-8 RECEPTOR A (C) | VdWContact |
| Phe 65 | 132 | Helix | VAL 27 | INTERLEUKIN-8 PRECURSOR (B) | Hydrophobic |
| Phe 65 | 132 | Helix | GLU 29 | INTERLEUKIN-8 PRECURSOR (B) | Hydrophobic |
| Phe 65 | 132 | Helix | GLU 29 | INTERLEUKIN-8 PRECURSOR (B) | VdWContact |
| Arg 68 | 135 | Helix | GLU 29 | INTERLEUKIN-8 PRECURSOR (B) | Cationic |
| Arg 68 | 135 | Helix | GLU 29 | INTERLEUKIN-8 PRECURSOR (B) | VdWContact |
| Ala 69 | 136 | C-term | GLU 29 | INTERLEUKIN-8 PRECURSOR (B) | Hydrophobic |
| Ala 69 | 136 | C-term | THR 37 | INTERLEUKIN-8 PRECURSOR (B) | Hydrophobic |
| Ala 69 | 136 | C-term | THR 37 | INTERLEUKIN-8 PRECURSOR (B) | HBAcceptor |
| Ala 69 | 136 | C-term | THR 37 | INTERLEUKIN-8 PRECURSOR (B) | VdWContact |
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