Interactions for 1QE6 (chain D)


Structure details


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Chemokine diagram


E S G P H C A N T E 30s-loop S D G R 40s-loop D P K E 50s-loopN-term M T S K L A V A L L A A F L I S A A L C E G A V L P R S A K E L R C Q C I K T Y S K P F H P K F N-termC-term A E N S C-term I V R L E K I I I V K L L C L E N W V Q R V V E K F L K R
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Interactions found in structure


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Chemokine Residue Generic number Segment Partner Residue Partner Interaction Type
Lys 20 81 N-loop CYS 5 INTERLEUKIN-8 VARIANT (B) Cationic
Lys 23 84 B1 GLU 29 INTERLEUKIN-8 VARIANT (C) HBAcceptor
Lys 23 84 B1 GLU 29 INTERLEUKIN-8 VARIANT (C) VdWContact
Glu 24 85 B1 VAL 27 INTERLEUKIN-8 VARIANT (C) VdWContact
Glu 24 85 B1 ARG 26 INTERLEUKIN-8 VARIANT (C) HBAcceptor
Glu 24 85 B1 ARG 26 INTERLEUKIN-8 VARIANT (C) Anionic
Glu 24 85 B1 ARG 26 INTERLEUKIN-8 VARIANT (C) VdWContact
Glu 24 85 B1 ILE 28 INTERLEUKIN-8 VARIANT (C) Hydrophobic
Glu 24 85 B1 ILE 28 INTERLEUKIN-8 VARIANT (C) VdWContact
Leu 25 86 B1 ARG 26 INTERLEUKIN-8 VARIANT (C) VdWContact
Leu 25 86 B1 VAL 27 INTERLEUKIN-8 VARIANT (C) Hydrophobic
Leu 25 86 B1 VAL 27 INTERLEUKIN-8 VARIANT (C) HBAcceptor
Leu 25 86 B1 VAL 27 INTERLEUKIN-8 VARIANT (C) HBDonor
Leu 25 86 B1 VAL 27 INTERLEUKIN-8 VARIANT (C) VdWContact
Arg 26 87 B1 GLU 24 INTERLEUKIN-8 VARIANT (C) HBDonor
Arg 26 87 B1 GLU 24 INTERLEUKIN-8 VARIANT (C) Cationic
Arg 26 87 B1 GLU 24 INTERLEUKIN-8 VARIANT (C) VdWContact
Arg 26 87 B1 LEU 25 INTERLEUKIN-8 VARIANT (C) VdWContact
Arg 26 87 B1 ARG 26 INTERLEUKIN-8 VARIANT (C) Hydrophobic
Arg 26 87 B1 ARG 26 INTERLEUKIN-8 VARIANT (C) VdWContact
Val 27 88 B1 GLU 24 INTERLEUKIN-8 VARIANT (C) VdWContact
Val 27 88 B1 PHE 65 INTERLEUKIN-8 VARIANT (C) Hydrophobic
Val 27 88 B1 LEU 25 INTERLEUKIN-8 VARIANT (C) Hydrophobic
Val 27 88 B1 LEU 25 INTERLEUKIN-8 VARIANT (C) HBAcceptor
Val 27 88 B1 LEU 25 INTERLEUKIN-8 VARIANT (C) HBDonor
Val 27 88 B1 LEU 25 INTERLEUKIN-8 VARIANT (C) VdWContact
Val 27 88 B1 LEU 66 INTERLEUKIN-8 VARIANT (C) Hydrophobic
Val 27 88 B1 ALA 69 INTERLEUKIN-8 VARIANT (C) Hydrophobic
Ile 28 89 B1 GLU 24 INTERLEUKIN-8 VARIANT (C) Hydrophobic
Ile 28 89 B1 GLU 24 INTERLEUKIN-8 VARIANT (C) VdWContact
Glu 29 90 30s-loop LYS 23 INTERLEUKIN-8 VARIANT (C) HBDonor
Glu 29 90 30s-loop LYS 23 INTERLEUKIN-8 VARIANT (C) VdWContact
Glu 29 90 30s-loop PHE 65 INTERLEUKIN-8 VARIANT (C) Hydrophobic
Glu 29 90 30s-loop ARG 68 INTERLEUKIN-8 VARIANT (C) HBAcceptor
Glu 29 90 30s-loop ARG 68 INTERLEUKIN-8 VARIANT (C) Anionic
Glu 29 90 30s-loop ARG 68 INTERLEUKIN-8 VARIANT (C) VdWContact
Glu 29 90 30s-loop ALA 69 INTERLEUKIN-8 VARIANT (C) Hydrophobic
Ser 30 91 30s-loop SER 72 INTERLEUKIN-8 VARIANT (C) HBAcceptor
Ser 30 91 30s-loop SER 72 INTERLEUKIN-8 VARIANT (C) VdWContact
Thr 37 99 30s-loop SER 72 INTERLEUKIN-8 VARIANT (C) HBDonor
Thr 37 99 30s-loop SER 72 INTERLEUKIN-8 VARIANT (C) VdWContact
Thr 37 99 30s-loop ALA 69 INTERLEUKIN-8 VARIANT (C) Hydrophobic
Thr 37 99 30s-loop ALA 69 INTERLEUKIN-8 VARIANT (C) HBDonor
Thr 37 99 30s-loop ALA 69 INTERLEUKIN-8 VARIANT (C) VdWContact
Lys 54 121 50s-loop SER 72 INTERLEUKIN-8 VARIANT (C) Cationic
Lys 54 121 50s-loop SER 72 INTERLEUKIN-8 VARIANT (C) VdWContact
Lys 54 121 50s-loop ASN 71 INTERLEUKIN-8 VARIANT (C) VdWContact
Gln 59 126 Helix GLU 70 INTERLEUKIN-8 VARIANT (C) Hydrophobic
Val 62 129 Helix LEU 66 INTERLEUKIN-8 VARIANT (C) Hydrophobic
Val 62 129 Helix LEU 66 INTERLEUKIN-8 VARIANT (C) VdWContact
Phe 65 132 Helix VAL 27 INTERLEUKIN-8 VARIANT (C) Hydrophobic
Phe 65 132 Helix GLU 29 INTERLEUKIN-8 VARIANT (C) Hydrophobic
Leu 66 133 Helix VAL 62 INTERLEUKIN-8 VARIANT (C) Hydrophobic
Leu 66 133 Helix VAL 27 INTERLEUKIN-8 VARIANT (C) Hydrophobic
Arg 68 135 Helix GLU 29 INTERLEUKIN-8 VARIANT (C) HBDonor
Arg 68 135 Helix GLU 29 INTERLEUKIN-8 VARIANT (C) Cationic
Arg 68 135 Helix GLU 29 INTERLEUKIN-8 VARIANT (C) VdWContact
Ala 69 136 C-term THR 37 INTERLEUKIN-8 VARIANT (C) Hydrophobic
Ala 69 136 C-term THR 37 INTERLEUKIN-8 VARIANT (C) HBAcceptor
Ala 69 136 C-term THR 37 INTERLEUKIN-8 VARIANT (C) VdWContact
Ala 69 136 C-term VAL 27 INTERLEUKIN-8 VARIANT (C) Hydrophobic
Ala 69 136 C-term GLU 29 INTERLEUKIN-8 VARIANT (C) Hydrophobic
Ala 69 136 C-term GLU 29 INTERLEUKIN-8 VARIANT (C) VdWContact
Glu 70 137 C-term LYS 54 INTERLEUKIN-8 VARIANT (C) VdWContact
Ser 72 139 C-term LYS 20 INTERLEUKIN-8 VARIANT (A) HBAcceptor
Ser 72 139 C-term LYS 20 INTERLEUKIN-8 VARIANT (A) Anionic
Ser 72 139 C-term LYS 20 INTERLEUKIN-8 VARIANT (A) VdWContact
Ser 72 139 C-term SER 30 INTERLEUKIN-8 VARIANT (C) VdWContact
Ser 72 139 C-term LYS 54 INTERLEUKIN-8 VARIANT (C) HBAcceptor
Ser 72 139 C-term LYS 54 INTERLEUKIN-8 VARIANT (C) Anionic
Ser 72 139 C-term LYS 54 INTERLEUKIN-8 VARIANT (C) VdWContact

Ligand interaction network


SO4_B_134

SO4_D_101

SO4_D_190

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