Interactions for 2IL8 (chain A)
Structure details
- PDB ID: 2IL8 open_in_new
- Protein: CXCL8_HUMAN
- Organism: Homo sapiens
- UniProt ID: P10145 open_in_new
- Method: Solution nmr
- Resolution: 0.0 Å
- Date: Jan. 15, 1991
- Reference: 10.1021/BI00459A004 open_in_new
- State: dimer
Chemokine diagram
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Interactions found in structure
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| Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
|---|---|---|---|---|---|
| Lys 23 | 84 | B1 | GLU 29 | INTERLEUKIN-8 (B) | HBAcceptor |
| Lys 23 | 84 | B1 | GLU 29 | INTERLEUKIN-8 (B) | VdWContact |
| Glu 24 | 85 | B1 | VAL 27 | INTERLEUKIN-8 (B) | VdWContact |
| Glu 24 | 85 | B1 | ILE 28 | INTERLEUKIN-8 (B) | Hydrophobic |
| Glu 24 | 85 | B1 | ARG 26 | INTERLEUKIN-8 (B) | Anionic |
| Leu 25 | 86 | B1 | VAL 27 | INTERLEUKIN-8 (B) | Hydrophobic |
| Leu 25 | 86 | B1 | VAL 27 | INTERLEUKIN-8 (B) | HBAcceptor |
| Leu 25 | 86 | B1 | VAL 27 | INTERLEUKIN-8 (B) | HBDonor |
| Leu 25 | 86 | B1 | VAL 27 | INTERLEUKIN-8 (B) | VdWContact |
| Arg 26 | 87 | B1 | ARG 26 | INTERLEUKIN-8 (B) | Hydrophobic |
| Arg 26 | 87 | B1 | GLU 24 | INTERLEUKIN-8 (B) | Cationic |
| Val 27 | 88 | B1 | LEU 25 | INTERLEUKIN-8 (B) | Hydrophobic |
| Val 27 | 88 | B1 | LEU 25 | INTERLEUKIN-8 (B) | HBAcceptor |
| Val 27 | 88 | B1 | LEU 25 | INTERLEUKIN-8 (B) | HBDonor |
| Val 27 | 88 | B1 | LEU 25 | INTERLEUKIN-8 (B) | VdWContact |
| Val 27 | 88 | B1 | GLU 24 | INTERLEUKIN-8 (B) | VdWContact |
| Val 27 | 88 | B1 | PHE 65 | INTERLEUKIN-8 (B) | Hydrophobic |
| Ile 28 | 89 | B1 | GLU 24 | INTERLEUKIN-8 (B) | Hydrophobic |
| Glu 29 | 90 | 30s-loop | ALA 69 | INTERLEUKIN-8 (B) | Hydrophobic |
| Glu 29 | 90 | 30s-loop | ALA 69 | INTERLEUKIN-8 (B) | VdWContact |
| Glu 29 | 90 | 30s-loop | LYS 23 | INTERLEUKIN-8 (B) | HBDonor |
| Glu 29 | 90 | 30s-loop | LYS 23 | INTERLEUKIN-8 (B) | VdWContact |
| Glu 29 | 90 | 30s-loop | PHE 65 | INTERLEUKIN-8 (B) | Hydrophobic |
| Glu 29 | 90 | 30s-loop | ARG 68 | INTERLEUKIN-8 (B) | VdWContact |
| Thr 37 | 99 | 30s-loop | ALA 69 | INTERLEUKIN-8 (B) | Hydrophobic |
| Thr 37 | 99 | 30s-loop | ALA 69 | INTERLEUKIN-8 (B) | HBDonor |
| Thr 37 | 99 | 30s-loop | ALA 69 | INTERLEUKIN-8 (B) | VdWContact |
| Phe 65 | 132 | Helix | GLU 29 | INTERLEUKIN-8 (B) | Hydrophobic |
| Phe 65 | 132 | Helix | VAL 27 | INTERLEUKIN-8 (B) | Hydrophobic |
| Arg 68 | 135 | Helix | GLU 29 | INTERLEUKIN-8 (B) | VdWContact |
| Ala 69 | 136 | C-term | GLU 29 | INTERLEUKIN-8 (B) | Hydrophobic |
| Ala 69 | 136 | C-term | GLU 29 | INTERLEUKIN-8 (B) | VdWContact |
| Ala 69 | 136 | C-term | THR 37 | INTERLEUKIN-8 (B) | Hydrophobic |
| Ala 69 | 136 | C-term | THR 37 | INTERLEUKIN-8 (B) | HBAcceptor |
| Ala 69 | 136 | C-term | THR 37 | INTERLEUKIN-8 (B) | VdWContact |
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