Interactions for 2K01 (chain C)
Structure details
- PDB ID: 2K01 open_in_new
- Protein: CXCL12_HUMAN
- Organism: Homo sapiens
- UniProt ID: P48061 open_in_new
- Method: Solution nmr
- Resolution: 0.0 Å
- Date: Oct. 28, 2008
- Reference: 10.1126/SCISIGNAL.1160755 open_in_new
- State: dimer
Chemokine diagram
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Interactions found in structure
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| Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
|---|---|---|---|---|---|
| Pro 202 | 56 | N-term | HIS 25 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Pro 202 | 56 | N-term | HIS 25 | Stromal cell-derived factor 1 (A) | VdWContact |
| Lys 224 | 84 | B1 | ASN 30 | Stromal cell-derived factor 1 (A) | HBAcceptor |
| Lys 224 | 84 | B1 | ASN 30 | Stromal cell-derived factor 1 (A) | VdWContact |
| His 225 | 85 | B1 | LYS 27 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| His 225 | 85 | B1 | ILE 28 | Stromal cell-derived factor 1 (A) | VdWContact |
| His 225 | 85 | B1 | PRO 2 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Leu 226 | 86 | B1 | LYS 27 | Stromal cell-derived factor 1 (A) | VdWContact |
| Leu 226 | 86 | B1 | ILE 28 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Leu 226 | 86 | B1 | ILE 28 | Stromal cell-derived factor 1 (A) | HBAcceptor |
| Leu 226 | 86 | B1 | ILE 28 | Stromal cell-derived factor 1 (A) | HBDonor |
| Leu 226 | 86 | B1 | ILE 28 | Stromal cell-derived factor 1 (A) | VdWContact |
| Lys 227 | 87 | B1 | HIS 25 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Lys 227 | 87 | B1 | LEU 26 | Stromal cell-derived factor 1 (A) | VdWContact |
| Ile 228 | 88 | B1 | TYR 61 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Ile 228 | 88 | B1 | TYR 61 | Stromal cell-derived factor 1 (A) | HBAcceptor |
| Ile 228 | 88 | B1 | TYR 61 | Stromal cell-derived factor 1 (A) | VdWContact |
| Ile 228 | 88 | B1 | HIS 25 | Stromal cell-derived factor 1 (A) | VdWContact |
| Ile 228 | 88 | B1 | LEU 26 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Ile 228 | 88 | B1 | LEU 26 | Stromal cell-derived factor 1 (A) | HBAcceptor |
| Ile 228 | 88 | B1 | LEU 26 | Stromal cell-derived factor 1 (A) | HBDonor |
| Ile 228 | 88 | B1 | LEU 26 | Stromal cell-derived factor 1 (A) | VdWContact |
| Leu 229 | 89 | B1 | HIS 25 | Stromal cell-derived factor 1 (A) | VdWContact |
| Asn 230 | 90 | 30s-loop | TYR 61 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Asn 230 | 90 | 30s-loop | TYR 61 | Stromal cell-derived factor 1 (A) | VdWContact |
| Asn 230 | 90 | 30s-loop | VAL 23 | Stromal cell-derived factor 1 (A) | VdWContact |
| Asn 230 | 90 | 30s-loop | LYS 24 | Stromal cell-derived factor 1 (A) | HBDonor |
| Asn 230 | 90 | 30s-loop | LYS 24 | Stromal cell-derived factor 1 (A) | VdWContact |
| Asn 230 | 90 | 30s-loop | ARG 20 | Stromal cell-derived factor 1 (A) | HBAcceptor |
| Asn 230 | 90 | 30s-loop | ARG 20 | Stromal cell-derived factor 1 (A) | VdWContact |
| Ala 235 | 97 | 30s-loop | LYS 68 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Ala 235 | 97 | 30s-loop | LYS 68 | Stromal cell-derived factor 1 (A) | VdWContact |
| Leu 236 | 99 | 30s-loop | CYS 65 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Leu 236 | 99 | 30s-loop | CYS 65 | Stromal cell-derived factor 1 (A) | VdWContact |
| Leu 236 | 99 | 30s-loop | LYS 64 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Ile 238 | 101 | B2 | CYS 65 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Pro 253 | 120 | 50s-loop | CYS 65 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Pro 253 | 120 | 50s-loop | CYS 65 | Stromal cell-derived factor 1 (A) | VdWContact |
| Gln 259 | 126 | Helix | CYS 65 | Stromal cell-derived factor 1 (A) | VdWContact |
| Gln 259 | 126 | Helix | ASN 67 | Stromal cell-derived factor 1 (A) | VdWContact |
| Gln 259 | 126 | Helix | LEU 66 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Gln 259 | 126 | Helix | LEU 66 | Stromal cell-derived factor 1 (A) | VdWContact |
| Tyr 261 | 128 | Helix | ASN 30 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Tyr 261 | 128 | Helix | ASN 30 | Stromal cell-derived factor 1 (A) | HBAcceptor |
| Tyr 261 | 128 | Helix | ASN 30 | Stromal cell-derived factor 1 (A) | HBDonor |
| Tyr 261 | 128 | Helix | ASN 30 | Stromal cell-derived factor 1 (A) | VdWContact |
| Tyr 261 | 128 | Helix | ILE 28 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Tyr 261 | 128 | Helix | ILE 28 | Stromal cell-derived factor 1 (A) | VdWContact |
| Leu 262 | 129 | Helix | CYS 65 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Leu 262 | 129 | Helix | LEU 62 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Leu 262 | 129 | Helix | LEU 62 | Stromal cell-derived factor 1 (A) | VdWContact |
| Leu 262 | 129 | Helix | LEU 66 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Leu 262 | 129 | Helix | LEU 66 | Stromal cell-derived factor 1 (A) | VdWContact |
| Ala 265 | 132 | Helix | CYS 36 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Ala 265 | 132 | Helix | CYS 36 | Stromal cell-derived factor 1 (A) | VdWContact |
| Ala 265 | 132 | Helix | PRO 53 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Ala 265 | 132 | Helix | PRO 53 | Stromal cell-derived factor 1 (A) | VdWContact |
| Ala 265 | 132 | Helix | LEU 62 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Ala 265 | 132 | Helix | ILE 38 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Leu 266 | 133 | Helix | LEU 66 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Leu 266 | 133 | Helix | LEU 62 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Leu 266 | 133 | Helix | LEU 62 | Stromal cell-derived factor 1 (A) | VdWContact |
| Leu 266 | 133 | Helix | GLN 59 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Leu 266 | 133 | Helix | GLN 59 | Stromal cell-derived factor 1 (A) | VdWContact |
| Asn 267 | 134 | Helix | GLN 59 | Stromal cell-derived factor 1 (A) | HBDonor |
| Asn 267 | 134 | Helix | GLN 59 | Stromal cell-derived factor 1 (A) | VdWContact |
| Lys 268 | 135 | Helix | ALA 35 | Stromal cell-derived factor 1 (A) | Hydrophobic |
| Lys 268 | 135 | Helix | ALA 35 | Stromal cell-derived factor 1 (A) | VdWContact |
| Lys 268 | 135 | Helix | LYS 54 | Stromal cell-derived factor 1 (A) | HBAcceptor |
| Lys 268 | 135 | Helix | LYS 54 | Stromal cell-derived factor 1 (A) | Anionic |
| Lys 268 | 135 | Helix | LYS 54 | Stromal cell-derived factor 1 (A) | VdWContact |
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