Interactions for 2Q8R (chain E)
Structure details
- PDB ID: 2Q8R open_in_new
- Protein: CCL14_HUMAN
- Organism: Homo sapiens
- UniProt ID: Q16627 open_in_new
- Method: X-ray
- Resolution: 1.82 Å
- Date: Sept. 11, 2007
- Reference: 10.1021/BI700936W open_in_new
- State: dimer
Chemokine diagram
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Interactions found in structure
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| Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
|---|---|---|---|---|---|
| Gly 1 | 56 | N-term | GLU 7 | CCL14 (G) | VdWContact |
| Pro 2 | 57 | N-term | ILE 40 | CCL14 (G) | Hydrophobic |
| Pro 2 | 57 | N-term | TYR 26 | CCL14 (G) | Hydrophobic |
| Tyr 3 | 58 | N-term | THR 11 | CCL14 (H) | Hydrophobic |
| Tyr 3 | 58 | N-term | THR 11 | CCL14 (H) | VdWContact |
| Tyr 3 | 58 | N-term | TYR 15 | CCL14 (H) | Hydrophobic |
| Tyr 3 | 58 | N-term | TYR 15 | CCL14 (H) | VdWContact |
| Tyr 3 | 58 | N-term | THR 13 | CCL14 (H) | VdWContact |
| Tyr 3 | 58 | N-term | ILE 40 | CCL14 (G) | Hydrophobic |
| Tyr 3 | 58 | N-term | VAL 47 | CCL14 (H) | Hydrophobic |
| Tyr 3 | 58 | N-term | CYS 48 | CCL14 (H) | HBAcceptor |
| Tyr 3 | 58 | N-term | CYS 48 | CCL14 (H) | VdWContact |
| Tyr 3 | 58 | N-term | THR 14 | CCL14 (H) | Hydrophobic |
| Tyr 3 | 58 | N-term | THR 14 | CCL14 (H) | HBAcceptor |
| Tyr 3 | 58 | N-term | THR 14 | CCL14 (H) | VdWContact |
| Tyr 3 | 58 | N-term | ASP 24 | CCL14 (G) | Hydrophobic |
| Tyr 3 | 58 | N-term | ASP 24 | CCL14 (G) | HBDonor |
| Tyr 3 | 58 | N-term | ASP 24 | CCL14 (G) | VdWContact |
| His 4 | 59 | N-term | SER 46 | CCL14 (H) | VdWContact |
| Pro 5 | 60 | N-term | VAL 38 | CCL14 (H) | Hydrophobic |
| Pro 5 | 60 | N-term | CYS 8 | CCL14 (H) | VdWContact |
| Pro 5 | 60 | N-term | GLU 7 | CCL14 (H) | Hydrophobic |
| Ser 6 | 61 | N-term | CYS 8 | CCL14 (H) | HBAcceptor |
| Ser 6 | 61 | N-term | CYS 8 | CCL14 (H) | HBDonor |
| Ser 6 | 61 | N-term | CYS 8 | CCL14 (H) | VdWContact |
| Glu 7 | 62 | N-term | SER 6 | CCL14 (H) | VdWContact |
| Glu 7 | 62 | N-term | PRO 5 | CCL14 (H) | Hydrophobic |
| Glu 7 | 62 | N-term | PRO 5 | CCL14 (H) | VdWContact |
| Glu 7 | 62 | N-term | HIS 45 | CCL14 (F) | Anionic |
| Cys 8 | 63 | CX | SER 6 | CCL14 (H) | HBAcceptor |
| Cys 8 | 63 | CX | SER 6 | CCL14 (H) | HBDonor |
| Cys 8 | 63 | CX | SER 6 | CCL14 (H) | VdWContact |
| Cys 8 | 63 | CX | PRO 5 | CCL14 (H) | VdWContact |
| Phe 10 | 68 | N-loop | SER 6 | CCL14 (H) | VdWContact |
| Phe 10 | 68 | N-loop | GLN 31 | CCL14 (H) | Hydrophobic |
| Thr 11 | 69 | N-loop | PRO 2 | CCL14 (H) | HBDonor |
| Thr 11 | 69 | N-loop | PRO 2 | CCL14 (H) | VdWContact |
| Thr 13 | 71 | N-loop | TYR 3 | CCL14 (H) | VdWContact |
| Met 23 | 84 | B1 | TYR 15 | CCL14 (F) | Hydrophobic |
| Asp 24 | 85 | B1 | TYR 3 | CCL14 (G) | Hydrophobic |
| Asp 24 | 85 | B1 | TYR 3 | CCL14 (G) | HBAcceptor |
| Asp 24 | 85 | B1 | TYR 3 | CCL14 (G) | VdWContact |
| Asp 24 | 85 | B1 | THR 14 | CCL14 (F) | Hydrophobic |
| Tyr 26 | 87 | B1 | PRO 2 | CCL14 (G) | Hydrophobic |
| Gln 31 | 94 | 30s-loop | PHE 10 | CCL14 (H) | Hydrophobic |
| Val 38 | 102 | B2 | PRO 5 | CCL14 (H) | Hydrophobic |
| Ile 40 | 104 | B2 | TYR 3 | CCL14 (G) | Hydrophobic |
| Ile 40 | 104 | B2 | PRO 2 | CCL14 (G) | Hydrophobic |
| Ile 40 | 104 | B2 | TYR 15 | CCL14 (F) | Hydrophobic |
| Gly 44 | 113 | 40s-loop | ARG 21 | CCL14 (F) | HBAcceptor |
| Gly 44 | 113 | 40s-loop | ARG 21 | CCL14 (F) | VdWContact |
| Ser 46 | 115 | B3 | HIS 4 | CCL14 (H) | VdWContact |
| Val 47 | 116 | B3 | TYR 3 | CCL14 (H) | Hydrophobic |
| Cys 48 | 117 | B3 | TYR 3 | CCL14 (H) | HBDonor |
| Cys 48 | 117 | B3 | TYR 3 | CCL14 (H) | VdWContact |
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