Interactions for 2X6G (chain L)
Structure details
- PDB ID: 2X6G open_in_new
- Protein: CCL3_HUMAN
- Organism: Homo sapiens
- UniProt ID: P10147 open_in_new
- Method: X-ray
- Resolution: 2.15 Å
- Date: Nov. 3, 2010
- Reference: 10.1038/EMBOJ.2010.256 open_in_new
- State: oligomer
Chemokine diagram
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Interactions found in structure
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| Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
|---|---|---|---|---|---|
| Pro 8 | 60 | N-term | ILE 41 | C-C MOTIF CHEMOKINE 3 (K) | Hydrophobic |
| Pro 8 | 60 | N-term | GLN 49 | C-C MOTIF CHEMOKINE 3 (K) | Hydrophobic |
| Thr 9 | 61 | N-term | CYS 11 | C-C MOTIF CHEMOKINE 3 (K) | HBAcceptor |
| Thr 9 | 61 | N-term | CYS 11 | C-C MOTIF CHEMOKINE 3 (K) | VdWContact |
| Thr 9 | 61 | N-term | PHE 13 | C-C MOTIF CHEMOKINE 3 (K) | Hydrophobic |
| Thr 9 | 61 | N-term | PHE 13 | C-C MOTIF CHEMOKINE 3 (K) | VdWContact |
| Ala 10 | 62 | N-term | THR 9 | C-C MOTIF CHEMOKINE 3 (K) | VdWContact |
| Ala 10 | 62 | N-term | PRO 8 | C-C MOTIF CHEMOKINE 3 (K) | Hydrophobic |
| Cys 11 | 63 | CX | THR 9 | C-C MOTIF CHEMOKINE 3 (K) | HBAcceptor |
| Cys 11 | 63 | CX | THR 9 | C-C MOTIF CHEMOKINE 3 (K) | HBDonor |
| Cys 11 | 63 | CX | THR 9 | C-C MOTIF CHEMOKINE 3 (K) | VdWContact |
| Phe 13 | 68 | N-loop | CYS 11 | C-C MOTIF CHEMOKINE 3 (K) | VdWContact |
| Phe 13 | 68 | N-loop | THR 9 | C-C MOTIF CHEMOKINE 3 (K) | Hydrophobic |
| Phe 13 | 68 | N-loop | THR 9 | C-C MOTIF CHEMOKINE 3 (K) | VdWContact |
| Phe 13 | 68 | N-loop | GLN 34 | C-C MOTIF CHEMOKINE 3 (K) | Hydrophobic |
| Phe 13 | 68 | N-loop | GLN 34 | C-C MOTIF CHEMOKINE 3 (K) | VdWContact |
| Ser 14 | 69 | N-loop | ASP 6 | C-C MOTIF CHEMOKINE 3 (K) | VdWContact |
| Tyr 28 | 86 | B1 | ARG 48 | C-C MOTIF CHEMOKINE 3 (N) | VdWContact |
| Glu 30 | 88 | B1 | ARG 48 | C-C MOTIF CHEMOKINE 3 (N) | HBAcceptor |
| Glu 30 | 88 | B1 | ARG 48 | C-C MOTIF CHEMOKINE 3 (N) | Anionic |
| Glu 30 | 88 | B1 | ARG 48 | C-C MOTIF CHEMOKINE 3 (N) | VdWContact |
| Glu 30 | 88 | B1 | THR 16 | C-C MOTIF CHEMOKINE 3 (N) | HBAcceptor |
| Glu 30 | 88 | B1 | THR 16 | C-C MOTIF CHEMOKINE 3 (N) | VdWContact |
| Ser 33 | 91 | 30s-loop | SER 14 | C-C MOTIF CHEMOKINE 3 (N) | HBAcceptor |
| Ser 33 | 91 | 30s-loop | SER 14 | C-C MOTIF CHEMOKINE 3 (N) | VdWContact |
| Ser 33 | 91 | 30s-loop | TYR 15 | C-C MOTIF CHEMOKINE 3 (N) | VdWContact |
| Gln 34 | 94 | 30s-loop | SER 14 | C-C MOTIF CHEMOKINE 3 (N) | VdWContact |
| Gln 34 | 94 | 30s-loop | PHE 13 | C-C MOTIF CHEMOKINE 3 (K) | Hydrophobic |
| Ile 41 | 102 | B2 | PRO 8 | C-C MOTIF CHEMOKINE 3 (K) | Hydrophobic |
| Ile 41 | 102 | B2 | PRO 8 | C-C MOTIF CHEMOKINE 3 (K) | VdWContact |
| Arg 48 | 114 | 40s-loop | ASP 6 | C-C MOTIF CHEMOKINE 3 (K) | Cationic |
| Gln 49 | 115 | B3 | PRO 8 | C-C MOTIF CHEMOKINE 3 (K) | Hydrophobic |
| Cys 51 | 117 | B3 | ASP 6 | C-C MOTIF CHEMOKINE 3 (K) | HBDonor |
| Cys 51 | 117 | B3 | ASP 6 | C-C MOTIF CHEMOKINE 3 (K) | VdWContact |
| Val 63 | 129 | Helix | PHE 24 | C-C MOTIF CHEMOKINE 3 (N) | Hydrophobic |
| Leu 66 | 132 | Helix | ARG 46 | C-C MOTIF CHEMOKINE 3 (N) | Hydrophobic |
| Leu 66 | 132 | Helix | ARG 46 | C-C MOTIF CHEMOKINE 3 (N) | HBAcceptor |
| Leu 66 | 132 | Helix | ARG 46 | C-C MOTIF CHEMOKINE 3 (N) | VdWContact |
| Glu 67 | 133 | Helix | ARG 46 | C-C MOTIF CHEMOKINE 3 (N) | HBAcceptor |
| Glu 67 | 133 | Helix | ARG 46 | C-C MOTIF CHEMOKINE 3 (N) | VdWContact |
| Glu 67 | 133 | Helix | PHE 24 | C-C MOTIF CHEMOKINE 3 (N) | Hydrophobic |
| Glu 67 | 133 | Helix | PHE 24 | C-C MOTIF CHEMOKINE 3 (N) | VdWContact |
| Glu 67 | 133 | Helix | THR 44 | C-C MOTIF CHEMOKINE 3 (N) | HBAcceptor |
| Glu 67 | 133 | Helix | THR 44 | C-C MOTIF CHEMOKINE 3 (N) | VdWContact |
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