CCL3_HUMAN

  • Alternate name(s): C-C motif chemokine 3
  • Organism: Homo sapiens
  • UniProt ID: P10147 open_in_new


Wild type sequence

Residue N-term   CX   N-loop   B1   30s-loop   B2   40s-loop   B3   50s-loop   Helix   C-term  
  31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62   63 67   68 69 70 71 72 73 74 75 76 80 81 82   83 84 85 86 87 88 89   90 91 94 95 96 97 99 100   101 102 103 104 105   106 112 113 114   115 116 117 118   119 120 121 122   123 124 125 126 127 128 129 130 131 132 133 134 135   136  
Wild Type M Q V S T A A L A V L L C T M A L C N Q F S A S L A A D T P T A   C C   F S Y T S R Q I P Q N F   I A D Y F E T   S S Q C S K P G   V I F L T   K R S R   Q V C A   D P S E   E W V Q K Y V S D L E L S   A  

Snake Plot

S S Q C S K P G 30s-loop K R S R 40s-loop D P S E 50s-loopC-term M Q V S T A A L A V L L C T M A L C N Q F S A S L A A D T P T A C C F S Y T S R Q I P Q N F N-term T E F Y D A I V I F L T A C V Q E W V Q K Y V S D L E L S A
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List of structures

PDB Method Resolution State Publication date Reference
1B50 - A,B Nmr None Dimer 1999-07-22 10.1074/JBC.274.23.16077 open_in_new
1B53 - A,B Nmr None Dimer 1999-07-22 10.1074/JBC.274.23.16077 open_in_new
3FPU - B X-ray 1.76 Monomer 2010-01-12 10.1371/JOURNAL.PONE.0008514 open_in_new
3H44 - C,D X-ray 3.0 Dimer 2010-04-14 -
4ZKB - B X-ray 2.9 Monomer 2015-07-08 10.1016/J.STR.2015.04.023 open_in_new
7F1Q - R Cryo-em 2.9 Monomer 2021-07-14 10.1038/S41467-021-24438-5 open_in_new
7F1T - A X-ray 2.6 Monomer 2021-07-14 10.1038/S41467-021-24438-5 open_in_new
2X69 - A,B,C,D,E X-ray 2.65 Oligomer 2010-11-03 10.1038/EMBOJ.2010.256 open_in_new
2X6G - M,B,C,E,F,H,I,L,O,A,N,P,R,G,J,K,Q,D X-ray 2.15 Oligomer 2010-11-03 10.1038/EMBOJ.2010.256 open_in_new
5COR - B,C,E,F,H,I,A,G,J,D X-ray 2.55 Oligomer 2016-04-13 10.1073/PNAS.1523981113 open_in_new
3KBX - A,B,C,D,E X-ray 2.65 Oligomer 2010-10-27 -
5D65 - B,C,E,A,D X-ray 3.1 Oligomer 2016-04-20 10.1073/PNAS.1523981113 open_in_new
4RA8 - A,B,C,D,E X-ray 2.6 Oligomer 2014-09-24 10.1016/J.JMB.2015.01.012 open_in_new

Sequence alignment from structures

Generic Number 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 67 68 69 70 71 72 73 74 75 76 80 81 82 83 84 85 86 87 88 89 90 91 94 95 96 97 99 100 101 102 103 104 105 106 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136
Canonical Sequence M Q V S T A A L A V L L C T M A L C N Q F S A S L A A D T P T A C C F S Y T S R Q I P Q N F I A D Y F E T S S Q C S K P G V I F L T K R S R Q V C A D P S E E W V Q K Y V S D L E L S A
 
1B50 - A,B - - - - - - - - - - - - - - - - - - - - - - - S L A A D T P T A C C F S Y T S R Q I P Q N F I A A Y F E T S S Q C S K P G V I F L T K R S R Q V C A D P S E E W V Q K Y V S D L E L S A
1B53 - A,B - - - - - - - - - - - - - - - - - - - - - - - S L A A D T P T A C C F S - T S R Q I P Q N F I A A Y F E T S S Q C S K P G V I F L T K R S R Q V C A D P S E E W V Q K Y V S D L E L S A
3FPU - B - - - - - - - - - - - - - - - - - - - - - - - S L A A D T P T T C C F S Y T S R Q I P Q N F I A D Y F E T S S Q C S K P G V I F L T K R S R Q V C A D P S E E W V Q K Y V S D L E - - -
3H44 - C,D A S L A K R S R Q V - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - A S L A S R Q V
4ZKB - B - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - T A C C F S Y T S R Q I P - - - - - D Y F E T S S Q C S K P G V I F L T - - - R Q V C A D P S E E W V Q K Y V S D - - - - -
7F1Q - R - - - - - - - - - - - - - - - - - - - - - - - S L A A D T P T A C C F S Y C S R Q I P Q N F I A D Y F E T S S Q C S K P G V I F L T K R S R Q V C A D P S E E W V Q K Y V S D L E L S A
7F1T - A - - - - - - - - - - - - - - - - - - - - - - - - - A A D T P T A C C F S Y C S R Q I P Q N F I A D Y F E T S S Q C S K P G V I F L T K R S R Q V C A D P S E E W V Q K Y V S D L E L S A
2X69 - A,B,C,D,E - - - - - - - - - - - - - - - - - - - - - - - - - A A D T P T A C C F S Y T S R Q I P Q N F I A D Y F E T S S Q C S K P G V I F L T K R S R Q V C A D P S E E W V Q K Y V S D L E L S -
2X6G - M,B,C,E,F,H,I,L,O,A,N,P,R,G,J,K,Q,D - - - - - - - - - - - - - - - - - - - - - - - - L A A D T P T A C C F S Y T S R Q I P Q N F I A A Y F E T S S Q C S K P G V I F L T K R S R Q V C A D P S E E W V Q K Y V S D L E L S A
5COR - B,C,E,F,H,I,A,G,J,D - - - - - - - - - - - - - - - - - - - - - - A S L A A D T P T A C C F S Y T S R Q I P Q N F I A D Y F E T S S Q C S K P G V I F L T K R S R Q V C A D P S E E W V Q K Y V S D L E L S A
3KBX - A,B,C,D,E - - - - - - - - - - - - - - - - - - - - - - - - - A A D T P T A C C F S Y T S R Q I P Q N F I A D Y F E T S S Q C S K P G V I F L T K R S R Q V C A D P S E E W V Q K Y - - S D L E L S
5D65 - B,C,E,A,D - - - - - - - - - - - - - - - - - - - - - - A S L A A D T P T A C C F S Y T S R Q I P Q N F I A D Y F E T S S Q C S K P G V I F L T K R S R Q V C A D P S E E W V Q K Y V S D L E L S -
4RA8 - A,B,C,D,E - - - - - - - - - - - - - - - - - - - - - - A S L A A D T A T A C C F S Y T S R Q I P Q N F I A D Y F E T S S Q C S K P G V I F L T K R S R Q V C A D P S E E W V Q K Y V S D L E L S -