Interactions for 3HP3 (chain H)
Structure details
- PDB ID: 3HP3 open_in_new
- Protein: CXCL12_HUMAN
- Organism: Homo sapiens
- UniProt ID: P48061 open_in_new
- Method: X-ray
- Resolution: 2.2 Å
- Date: Jan. 26, 2010
- Reference: 10.1002/PROT.22666 open_in_new
- State: oligomer
Chemokine diagram
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Interactions found in structure
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Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
---|---|---|---|---|---|
Ser 4 | 58 | N-term | GLN 48 | CXCL12 protein (C) | HBDonor |
Ser 4 | 58 | N-term | GLN 48 | CXCL12 protein (C) | VdWContact |
Leu 5 | 59 | N-term | ARG 12 | CXCL12 protein (C) | HBAcceptor |
Leu 5 | 59 | N-term | ARG 12 | CXCL12 protein (C) | VdWContact |
Ser 6 | 60 | N-term | CYS 50 | CXCL12 protein (C) | HBAcceptor |
Ser 6 | 60 | N-term | CYS 50 | CXCL12 protein (C) | VdWContact |
Ser 6 | 60 | N-term | CYS 11 | CXCL12 protein (C) | VdWContact |
Ser 6 | 60 | N-term | GLU 15 | CXCL12 protein (C) | HBDonor |
Ser 6 | 60 | N-term | GLU 15 | CXCL12 protein (C) | VdWContact |
Ser 6 | 60 | N-term | ARG 12 | CXCL12 protein (C) | HBAcceptor |
Ser 6 | 60 | N-term | ARG 12 | CXCL12 protein (C) | VdWContact |
Ser 6 | 60 | N-term | PHE 13 | CXCL12 protein (C) | VdWContact |
Tyr 7 | 61 | N-term | LEU 29 | CXCL12 protein (C) | Hydrophobic |
Tyr 7 | 61 | N-term | GLN 48 | CXCL12 protein (C) | Hydrophobic |
Tyr 7 | 61 | N-term | GLN 48 | CXCL12 protein (C) | VdWContact |
Tyr 7 | 61 | N-term | VAL 39 | CXCL12 protein (C) | Hydrophobic |
Tyr 7 | 61 | N-term | PRO 10 | CXCL12 protein (C) | Hydrophobic |
Tyr 7 | 61 | N-term | PRO 10 | CXCL12 protein (C) | VdWContact |
Arg 8 | 62 | N-term | ARG 8 | CXCL12 protein (C) | VdWContact |
Arg 8 | 62 | N-term | CYS 9 | CXCL12 protein (C) | HBDonor |
Arg 8 | 62 | N-term | CYS 9 | CXCL12 protein (C) | VdWContact |
Arg 8 | 62 | N-term | PRO 10 | CXCL12 protein (C) | HBDonor |
Arg 8 | 62 | N-term | PRO 10 | CXCL12 protein (C) | VdWContact |
Cys 9 | 63 | CX | ARG 8 | CXCL12 protein (C) | HBAcceptor |
Cys 9 | 63 | CX | ARG 8 | CXCL12 protein (C) | VdWContact |
Pro 10 | 66 | CX | ARG 8 | CXCL12 protein (C) | HBAcceptor |
Pro 10 | 66 | CX | ARG 8 | CXCL12 protein (C) | VdWContact |
Pro 10 | 66 | CX | TYR 7 | CXCL12 protein (C) | Hydrophobic |
Pro 10 | 66 | CX | TYR 7 | CXCL12 protein (C) | VdWContact |
Pro 10 | 66 | CX | PRO 10 | CXCL12 protein (C) | Hydrophobic |
Arg 12 | 68 | N-loop | LEU 5 | CXCL12 protein (C) | HBDonor |
Arg 12 | 68 | N-loop | LEU 5 | CXCL12 protein (C) | VdWContact |
Arg 12 | 68 | N-loop | SER 6 | CXCL12 protein (C) | HBDonor |
Arg 12 | 68 | N-loop | SER 6 | CXCL12 protein (C) | VdWContact |
Phe 13 | 69 | N-loop | SER 6 | CXCL12 protein (C) | VdWContact |
Glu 15 | 71 | N-loop | SER 6 | CXCL12 protein (C) | HBAcceptor |
Glu 15 | 71 | N-loop | SER 6 | CXCL12 protein (C) | VdWContact |
Lys 27 | 87 | B1 | ASN 67 | CXCL12 protein (D) | Hydrophobic |
Lys 27 | 87 | B1 | ASN 67 | CXCL12 protein (D) | VdWContact |
Ile 28 | 88 | B1 | LEU 66 | CXCL12 protein (D) | Hydrophobic |
Ile 28 | 88 | B1 | ASN 67 | CXCL12 protein (D) | HBDonor |
Ile 28 | 88 | B1 | ASN 67 | CXCL12 protein (D) | VdWContact |
Ile 28 | 88 | B1 | GLU 63 | CXCL12 protein (D) | Hydrophobic |
Ile 28 | 88 | B1 | LEU 62 | CXCL12 protein (D) | Hydrophobic |
Leu 29 | 89 | B1 | TYR 7 | CXCL12 protein (C) | Hydrophobic |
Leu 29 | 89 | B1 | TYR 7 | CXCL12 protein (C) | VdWContact |
Leu 29 | 89 | B1 | THR 31 | CXCL12 protein (C) | Hydrophobic |
Leu 29 | 89 | B1 | THR 31 | CXCL12 protein (C) | VdWContact |
Asn 30 | 90 | 30s-loop | GLN 59 | CXCL12 protein (D) | Hydrophobic |
Asn 30 | 90 | 30s-loop | GLU 63 | CXCL12 protein (D) | Hydrophobic |
Asn 30 | 90 | 30s-loop | GLU 63 | CXCL12 protein (D) | HBDonor |
Asn 30 | 90 | 30s-loop | GLU 63 | CXCL12 protein (D) | VdWContact |
Thr 31 | 91 | 30s-loop | LEU 29 | CXCL12 protein (C) | Hydrophobic |
Thr 31 | 91 | 30s-loop | THR 31 | CXCL12 protein (C) | Hydrophobic |
Leu 36 | 99 | 30s-loop | LEU 36 | CXCL12 protein (D) | Hydrophobic |
Leu 36 | 99 | 30s-loop | LEU 62 | CXCL12 protein (D) | Hydrophobic |
Val 39 | 102 | B2 | TYR 7 | CXCL12 protein (C) | Hydrophobic |
Arg 41 | 104 | B2 | ASN 33 | CXCL12 protein (C) | HBDonor |
Arg 41 | 104 | B2 | ASN 33 | CXCL12 protein (C) | VdWContact |
Arg 47 | 114 | 40s-loop | LEU 5 | CXCL12 protein (C) | VdWContact |
Gln 48 | 115 | B3 | ASN 33 | CXCL12 protein (C) | VdWContact |
Gln 48 | 115 | B3 | TYR 7 | CXCL12 protein (C) | Hydrophobic |
Gln 48 | 115 | B3 | PRO 32 | CXCL12 protein (C) | Hydrophobic |
Cys 50 | 117 | B3 | SER 6 | CXCL12 protein (C) | HBDonor |
Cys 50 | 117 | B3 | SER 6 | CXCL12 protein (C) | VdWContact |
Pro 53 | 120 | 50s-loop | LEU 36 | CXCL12 protein (D) | Hydrophobic |
Lys 54 | 121 | 50s-loop | ASN 30 | CXCL12 protein (D) | HBAcceptor |
Lys 54 | 121 | 50s-loop | ASN 30 | CXCL12 protein (D) | VdWContact |
Gln 59 | 126 | Helix | ASN 30 | CXCL12 protein (D) | Hydrophobic |
Gln 59 | 126 | Helix | ASN 30 | CXCL12 protein (D) | HBAcceptor |
Gln 59 | 126 | Helix | ASN 30 | CXCL12 protein (D) | VdWContact |
Gln 59 | 126 | Helix | ILE 28 | CXCL12 protein (D) | Hydrophobic |
Tyr 61 | 128 | Helix | LEU 66 | CXCL12 protein (D) | Hydrophobic |
Tyr 61 | 128 | Helix | LEU 66 | CXCL12 protein (D) | VdWContact |
Leu 62 | 129 | Helix | LEU 66 | CXCL12 protein (D) | Hydrophobic |
Leu 62 | 129 | Helix | LEU 36 | CXCL12 protein (D) | Hydrophobic |
Leu 62 | 129 | Helix | ILE 28 | CXCL12 protein (D) | Hydrophobic |
Leu 62 | 129 | Helix | ILE 28 | CXCL12 protein (D) | VdWContact |
Leu 62 | 129 | Helix | LEU 62 | CXCL12 protein (D) | Hydrophobic |
Glu 63 | 130 | Helix | LYS 27 | CXCL12 protein (D) | Anionic |
Glu 63 | 130 | Helix | ILE 28 | CXCL12 protein (D) | Hydrophobic |
Lys 64 | 131 | Helix | LEU 66 | CXCL12 protein (D) | Hydrophobic |
Ala 65 | 132 | Helix | LEU 66 | CXCL12 protein (D) | Hydrophobic |
Ala 65 | 132 | Helix | LEU 62 | CXCL12 protein (D) | Hydrophobic |
Ala 65 | 132 | Helix | ALA 65 | CXCL12 protein (D) | Hydrophobic |
Leu 66 | 133 | Helix | LEU 26 | CXCL12 protein (D) | Hydrophobic |
Leu 66 | 133 | Helix | LEU 26 | CXCL12 protein (D) | VdWContact |
Leu 66 | 133 | Helix | ILE 28 | CXCL12 protein (D) | Hydrophobic |
Leu 66 | 133 | Helix | ILE 28 | CXCL12 protein (D) | VdWContact |
Leu 66 | 133 | Helix | TYR 61 | CXCL12 protein (D) | Hydrophobic |
Leu 66 | 133 | Helix | TYR 61 | CXCL12 protein (D) | VdWContact |
Leu 66 | 133 | Helix | LEU 62 | CXCL12 protein (D) | Hydrophobic |
Asn 67 | 134 | Helix | LYS 56 | CXCL12 protein (J) | VdWContact |