Interactions for 4RAL (chain D)
Structure details
- PDB ID: 4RAL open_in_new
- Protein: CCL4_HUMAN
- Organism: Homo sapiens
- UniProt ID: P13236 open_in_new
- Method: X-ray
- Resolution: 3.15 Å
- Date: May 13, 2015
- Reference: 10.1016/J.JMB.2015.01.012 open_in_new
- State: dimer
Chemokine diagram
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Interactions found in structure
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| Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
|---|---|---|---|---|---|
| Val 1 | 125 | Helix | GLY 339 | Insulin-degrading enzyme (A) | VdWContact |
| Val 1 | 125 | Helix | GLU 341 | Insulin-degrading enzyme (A) | VdWContact |
| Val 1 | 125 | Helix | GLY 361 | Insulin-degrading enzyme (A) | HBAcceptor |
| Val 1 | 125 | Helix | GLY 361 | Insulin-degrading enzyme (A) | VdWContact |
| Val 1 | 125 | Helix | LEU 359 | Insulin-degrading enzyme (A) | VdWContact |
| Val 1 | 125 | Helix | VAL 360 | Insulin-degrading enzyme (A) | Hydrophobic |
| Val 1 | 125 | Helix | VAL 360 | Insulin-degrading enzyme (A) | VdWContact |
| Gln 2 | 126 | Helix | GLY 361 | Insulin-degrading enzyme (A) | VdWContact |
| Gln 2 | 126 | Helix | HIS 336 | Insulin-degrading enzyme (A) | VdWContact |
| Gln 2 | 126 | Helix | TYR 609 | Insulin-degrading enzyme (A) | VdWContact |
| Glu 3 | 127 | Helix | ILE 374 | Insulin-degrading enzyme (A) | Hydrophobic |
| Glu 3 | 127 | Helix | LYS 364 | Insulin-degrading enzyme (A) | Hydrophobic |
| Glu 3 | 127 | Helix | LYS 364 | Insulin-degrading enzyme (A) | VdWContact |
| Val 42 | 129 | Helix | ALA 198 | Insulin-degrading enzyme (A) | Hydrophobic |
| Val 42 | 129 | Helix | ALA 198 | Insulin-degrading enzyme (A) | VdWContact |
| Val 42 | 129 | Helix | PHE 202 | Insulin-degrading enzyme (A) | Hydrophobic |
| Val 42 | 129 | Helix | TRP 199 | Insulin-degrading enzyme (A) | Hydrophobic |
| Tyr 43 | 130 | Helix | PHE 141 | Insulin-degrading enzyme (A) | Hydrophobic |
| Asp 44 | 131 | Helix | PHE 141 | Insulin-degrading enzyme (A) | VdWContact |
| Asp 44 | 131 | Helix | HIS 108 | Insulin-degrading enzyme (A) | Hydrophobic |
| Asp 44 | 131 | Helix | THR 220 | Insulin-degrading enzyme (A) | Hydrophobic |
| Asp 44 | 131 | Helix | THR 220 | Insulin-degrading enzyme (A) | VdWContact |
| Asp 44 | 131 | Helix | TRP 199 | Insulin-degrading enzyme (A) | Hydrophobic |
| Asp 44 | 131 | Helix | THR 142 | Insulin-degrading enzyme (A) | HBAcceptor |
| Asp 44 | 131 | Helix | THR 142 | Insulin-degrading enzyme (A) | VdWContact |
| Leu 45 | 132 | Helix | PHE 141 | Insulin-degrading enzyme (A) | Hydrophobic |
| Leu 45 | 132 | Helix | PHE 141 | Insulin-degrading enzyme (A) | VdWContact |
| Leu 45 | 132 | Helix | ALA 140 | Insulin-degrading enzyme (A) | VdWContact |
| Leu 45 | 132 | Helix | GLU 189 | Insulin-degrading enzyme (A) | VdWContact |
| Glu 46 | 133 | Helix | TYR 831 | Insulin-degrading enzyme (A) | VdWContact |
| Glu 46 | 133 | Helix | GLN 111 | Insulin-degrading enzyme (A) | VdWContact |
| Glu 46 | 133 | Helix | ASN 139 | Insulin-degrading enzyme (A) | VdWContact |
| Glu 46 | 133 | Helix | ARG 824 | Insulin-degrading enzyme (A) | HBAcceptor |
| Glu 46 | 133 | Helix | ARG 824 | Insulin-degrading enzyme (A) | VdWContact |
| Glu 46 | 133 | Helix | SER 138 | Insulin-degrading enzyme (A) | HBDonor |
| Glu 46 | 133 | Helix | ALA 140 | Insulin-degrading enzyme (A) | HBDonor |
| Glu 46 | 133 | Helix | ALA 140 | Insulin-degrading enzyme (A) | VdWContact |
| Glu 46 | 133 | Helix | PHE 115 | Insulin-degrading enzyme (A) | CationPi |
| Leu 47 | 134 | Helix | ASN 139 | Insulin-degrading enzyme (A) | HBAcceptor |
| Leu 47 | 134 | Helix | ASN 139 | Insulin-degrading enzyme (A) | HBDonor |
| Leu 47 | 134 | Helix | ASN 139 | Insulin-degrading enzyme (A) | VdWContact |
| Asn 48 | 135 | Helix | TYR 831 | Insulin-degrading enzyme (A) | Hydrophobic |
| Asn 48 | 135 | Helix | TYR 831 | Insulin-degrading enzyme (A) | VdWContact |
| Asn 48 | 135 | Helix | LYS 192 | Insulin-degrading enzyme (A) | VdWContact |
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