Interactions for 4RAL (chain E)
Structure details
- PDB ID: 4RAL open_in_new
- Protein: CCL4_HUMAN
- Organism: Homo sapiens
- UniProt ID: P13236 open_in_new
- Method: X-ray
- Resolution: 3.15 Å
- Date: May 13, 2015
- Reference: 10.1016/J.JMB.2015.01.012 open_in_new
- State: dimer
Chemokine diagram
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Interactions found in structure
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| Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
|---|---|---|---|---|---|
| Met 1 | 30 | N-term | GLY 339 | Insulin-degrading enzyme (B) | VdWContact |
| Met 1 | 30 | N-term | GLY 361 | Insulin-degrading enzyme (B) | HBAcceptor |
| Met 1 | 30 | N-term | GLY 361 | Insulin-degrading enzyme (B) | VdWContact |
| Met 1 | 30 | N-term | LEU 359 | Insulin-degrading enzyme (B) | VdWContact |
| Met 1 | 30 | N-term | VAL 360 | Insulin-degrading enzyme (B) | VdWContact |
| Lys 2 | 31 | N-term | GLY 361 | Insulin-degrading enzyme (B) | VdWContact |
| Lys 2 | 31 | N-term | HIS 336 | Insulin-degrading enzyme (B) | VdWContact |
| Leu 3 | 32 | N-term | ILE 374 | Insulin-degrading enzyme (B) | Hydrophobic |
| Leu 3 | 32 | N-term | ILE 374 | Insulin-degrading enzyme (B) | VdWContact |
| Cys 42 | 33 | N-term | PHE 202 | Insulin-degrading enzyme (B) | Hydrophobic |
| Cys 42 | 33 | N-term | PHE 202 | Insulin-degrading enzyme (B) | VdWContact |
| Cys 42 | 33 | N-term | TRP 199 | Insulin-degrading enzyme (B) | Hydrophobic |
| Cys 42 | 33 | N-term | ALA 198 | Insulin-degrading enzyme (B) | Hydrophobic |
| Val 43 | 34 | N-term | PHE 141 | Insulin-degrading enzyme (B) | Hydrophobic |
| Thr 44 | 35 | N-term | PHE 141 | Insulin-degrading enzyme (B) | VdWContact |
| Thr 44 | 35 | N-term | THR 220 | Insulin-degrading enzyme (B) | Hydrophobic |
| Thr 44 | 35 | N-term | TRP 199 | Insulin-degrading enzyme (B) | Hydrophobic |
| Thr 44 | 35 | N-term | THR 142 | Insulin-degrading enzyme (B) | HBAcceptor |
| Thr 44 | 35 | N-term | THR 142 | Insulin-degrading enzyme (B) | VdWContact |
| Val 45 | 36 | N-term | PHE 141 | Insulin-degrading enzyme (B) | Hydrophobic |
| Val 45 | 36 | N-term | ALA 140 | Insulin-degrading enzyme (B) | VdWContact |
| Val 45 | 36 | N-term | GLU 189 | Insulin-degrading enzyme (B) | VdWContact |
| Leu 46 | 37 | N-term | GLU 182 | Insulin-degrading enzyme (B) | Cationic |
| Leu 46 | 37 | N-term | GLU 182 | Insulin-degrading enzyme (B) | VdWContact |
| Leu 46 | 37 | N-term | TYR 831 | Insulin-degrading enzyme (B) | VdWContact |
| Leu 46 | 37 | N-term | GLN 111 | Insulin-degrading enzyme (B) | VdWContact |
| Leu 46 | 37 | N-term | ASN 139 | Insulin-degrading enzyme (B) | VdWContact |
| Leu 46 | 37 | N-term | ARG 824 | Insulin-degrading enzyme (B) | HBAcceptor |
| Leu 46 | 37 | N-term | ARG 824 | Insulin-degrading enzyme (B) | VdWContact |
| Leu 46 | 37 | N-term | HIS 112 | Insulin-degrading enzyme (B) | VdWContact |
| Leu 46 | 37 | N-term | ALA 140 | Insulin-degrading enzyme (B) | HBDonor |
| Leu 46 | 37 | N-term | ALA 140 | Insulin-degrading enzyme (B) | VdWContact |
| Leu 46 | 37 | N-term | PHE 115 | Insulin-degrading enzyme (B) | Hydrophobic |
| Leu 46 | 37 | N-term | PHE 115 | Insulin-degrading enzyme (B) | CationPi |
| Ser 47 | 38 | N-term | ASN 139 | Insulin-degrading enzyme (B) | HBAcceptor |
| Ser 47 | 38 | N-term | ASN 139 | Insulin-degrading enzyme (B) | HBDonor |
| Ser 47 | 38 | N-term | ASN 139 | Insulin-degrading enzyme (B) | VdWContact |
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