Interactions for 7RKF (chain L)
Structure details
- PDB ID: 7RKF open_in_new
- Protein: CX3CL1_HUMAN
- Organism: Homo sapiens
- UniProt ID: P78423 open_in_new
- Method: Cryo-em
- Resolution: 4.0 Å
- Date: Jan. 26, 2022
- Reference: 10.1126/SCIADV.ABL5442 open_in_new
- State: monomer
Chemokine diagram
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Interactions found in structure
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Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
---|---|---|---|---|---|
His 2 | 57 | N-term | PHE 111 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
His 2 | 57 | N-term | PHE 111 | G-protein coupled receptor homolog US28 (R) | PiStacking |
His 2 | 57 | N-term | TYR 40 | G-protein coupled receptor homolog US28 (R) | VdWContact |
His 2 | 57 | N-term | TYR 112 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
His 3 | 58 | N-term | LEU 273 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
Gly 4 | 59 | N-term | ILE 274 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Val 5 | 60 | N-term | LEU 93 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
Val 5 | 60 | N-term | LEU 93 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Thr 6 | 61 | N-term | LEU 29 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Asn 9 | 64 | CX | VAL 24 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
Asn 9 | 64 | CX | VAL 24 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Asn 9 | 64 | CX | PHE 25 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
Asn 9 | 64 | CX | PHE 25 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Cys 12 | 67 | CX | PRO 22 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Lys 14 | 69 | N-loop | ALA 20 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
Pro 20 | 76 | N-loop | ASP 15 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
Leu 23 | 82 | N-loop | ASP 15 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
Ala 32 | 92 | 30s-loop | ASP 170 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
Ser 33 | 94 | 30s-loop | MET 174 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Cys 34 | 95 | 30s-loop | MET 174 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
Cys 34 | 95 | 30s-loop | MET 174 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Arg 37 | 99 | 30s-loop | ASP 178 | G-protein coupled receptor homolog US28 (R) | Cationic |
Arg 37 | 99 | 30s-loop | ASP 178 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Leu 48 | 115 | B3 | PRO 22 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
Phe 49 | 116 | B3 | GLU 18 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |