Interactions for 7RKM (chain L)
Structure details
- PDB ID: 7RKM open_in_new
- Protein: CX3CL1_HUMAN
- Organism: Homo sapiens
- UniProt ID: P78423 open_in_new
- Method: Cryo-em
- Resolution: 3.5 Å
- Date: Jan. 26, 2022
- Reference: 10.1126/SCIADV.ABL5442 open_in_new
- State: monomer
Chemokine diagram
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Interactions found in structure
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Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
---|---|---|---|---|---|
His 2 | 57 | N-term | PHE 281 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
His 2 | 57 | N-term | TRP 89 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
His 2 | 57 | N-term | TRP 89 | G-protein coupled receptor homolog US28 (R) | PiStacking |
His 2 | 57 | N-term | PHE 111 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
His 2 | 57 | N-term | TYR 112 | G-protein coupled receptor homolog US28 (R) | HBAcceptor |
His 2 | 57 | N-term | TYR 112 | G-protein coupled receptor homolog US28 (R) | VdWContact |
His 2 | 57 | N-term | TYR 40 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
His 2 | 57 | N-term | TYR 40 | G-protein coupled receptor homolog US28 (R) | VdWContact |
His 3 | 58 | N-term | LEU 273 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
His 3 | 58 | N-term | LYS 270 | G-protein coupled receptor homolog US28 (R) | VdWContact |
His 3 | 58 | N-term | LEU 248 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
His 3 | 58 | N-term | GLU 277 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Gly 4 | 59 | N-term | ILE 274 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Val 5 | 60 | N-term | TRP 89 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
Val 5 | 60 | N-term | TYR 92 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
Val 5 | 60 | N-term | LEU 93 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
Val 5 | 60 | N-term | LEU 93 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Lys 7 | 62 | N-term | TYR 92 | G-protein coupled receptor homolog US28 (R) | HBDonor |
Lys 7 | 62 | N-term | TYR 92 | G-protein coupled receptor homolog US28 (R) | CationPi |
Lys 7 | 62 | N-term | TYR 92 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Lys 7 | 62 | N-term | GLN 172 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
Asn 9 | 64 | CX | PHE 25 | G-protein coupled receptor homolog US28 (R) | HBAcceptor |
Asn 9 | 64 | CX | PHE 25 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Ile 10 | 65 | CX | PRO 22 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
Ile 10 | 65 | CX | VAL 24 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
Ile 10 | 65 | CX | VAL 24 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Thr 11 | 66 | CX | CYS 23 | G-protein coupled receptor homolog US28 (R) | HBAcceptor |
Thr 11 | 66 | CX | CYS 23 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Thr 11 | 66 | CX | PRO 22 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Thr 16 | 71 | N-loop | ASP 17 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
Ile 19 | 75 | N-loop | TYR 16 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
Ala 32 | 92 | 30s-loop | MET 174 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
Ala 32 | 92 | 30s-loop | MET 174 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Ala 32 | 92 | 30s-loop | GLN 172 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Ser 33 | 94 | 30s-loop | CYS 173 | G-protein coupled receptor homolog US28 (R) | HBDonor |
Ser 33 | 94 | 30s-loop | CYS 173 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Ser 33 | 94 | 30s-loop | GLN 172 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Cys 34 | 95 | 30s-loop | TYR 177 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Gly 35 | 96 | 30s-loop | MET 174 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Gly 35 | 96 | 30s-loop | THR 175 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Ile 40 | 102 | B2 | PRO 22 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
Ile 40 | 102 | B2 | PRO 22 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Arg 47 | 114 | 40s-loop | TYR 16 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Phe 49 | 116 | B3 | THR 21 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
Phe 49 | 116 | B3 | TYR 16 | G-protein coupled receptor homolog US28 (R) | Hydrophobic |
Phe 49 | 116 | B3 | TYR 16 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Cys 50 | 117 | B3 | ALA 20 | G-protein coupled receptor homolog US28 (R) | HBDonor |
Cys 50 | 117 | B3 | ALA 20 | G-protein coupled receptor homolog US28 (R) | VdWContact |
Cys 50 | 117 | B3 | PRO 22 | G-protein coupled receptor homolog US28 (R) | VdWContact |