Interactions for 7RKM (chain L)


Structure details


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Chemokine diagram


Q A S C G K R A 30s-loop R Q H R 40s-loop D P K E 50s-loopN-term M A P I S L S W L L R L A T F C H L T V L L A G Q H H G V T K C N I T C S K M T S K I P V A L N-termC-term A A A L T R N G G T F E K Q I G E V K P R T T P A A G G M D E S V V L E P E A T G E S S S L E P T P S S Q E A Q R A L G T S P E L P T G V T G S S G T R L P P T P K A Q D G G P V G T E L F R V P P V S T A A T W Q S S A P H Q P G P S L W A E A K T S E A P S T Q D P S T Q A S T A S S P A P E E N A P S E G Q R V W G Q G Q S P R P E N S L E R E E M G P V P A H T D A F Q D W G P G S M A H V S V V P V S S E G T P S R E P V A S G S W T P K A E E P I H A T M D P Q R L G V L I T P V P D A Q A A T R R Q A V G L L A F L G L L F C L G V A M F T Y Q S L Q G C P R K M A G E M A E G L R Y I P R S C G S N S Y V L V P V C-term N Q Q Y H I L I I L E T A C F L Q W V K D A M Q H L D R Q
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Interactions found in structure


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Chemokine Residue Generic number Segment Partner Residue Partner Interaction Type
His 2 57 N-term PHE 281 G-protein coupled receptor homolog US28 (R) Hydrophobic
His 2 57 N-term TRP 89 G-protein coupled receptor homolog US28 (R) Hydrophobic
His 2 57 N-term TRP 89 G-protein coupled receptor homolog US28 (R) PiStacking
His 2 57 N-term PHE 111 G-protein coupled receptor homolog US28 (R) Hydrophobic
His 2 57 N-term TYR 112 G-protein coupled receptor homolog US28 (R) HBAcceptor
His 2 57 N-term TYR 112 G-protein coupled receptor homolog US28 (R) VdWContact
His 2 57 N-term TYR 40 G-protein coupled receptor homolog US28 (R) Hydrophobic
His 2 57 N-term TYR 40 G-protein coupled receptor homolog US28 (R) VdWContact
His 3 58 N-term LEU 273 G-protein coupled receptor homolog US28 (R) Hydrophobic
His 3 58 N-term LYS 270 G-protein coupled receptor homolog US28 (R) VdWContact
His 3 58 N-term LEU 248 G-protein coupled receptor homolog US28 (R) Hydrophobic
His 3 58 N-term GLU 277 G-protein coupled receptor homolog US28 (R) VdWContact
Gly 4 59 N-term ILE 274 G-protein coupled receptor homolog US28 (R) VdWContact
Val 5 60 N-term TRP 89 G-protein coupled receptor homolog US28 (R) Hydrophobic
Val 5 60 N-term TYR 92 G-protein coupled receptor homolog US28 (R) Hydrophobic
Val 5 60 N-term LEU 93 G-protein coupled receptor homolog US28 (R) Hydrophobic
Val 5 60 N-term LEU 93 G-protein coupled receptor homolog US28 (R) VdWContact
Lys 7 62 N-term TYR 92 G-protein coupled receptor homolog US28 (R) HBDonor
Lys 7 62 N-term TYR 92 G-protein coupled receptor homolog US28 (R) CationPi
Lys 7 62 N-term TYR 92 G-protein coupled receptor homolog US28 (R) VdWContact
Lys 7 62 N-term GLN 172 G-protein coupled receptor homolog US28 (R) Hydrophobic
Asn 9 64 CX PHE 25 G-protein coupled receptor homolog US28 (R) HBAcceptor
Asn 9 64 CX PHE 25 G-protein coupled receptor homolog US28 (R) VdWContact
Ile 10 65 CX PRO 22 G-protein coupled receptor homolog US28 (R) Hydrophobic
Ile 10 65 CX VAL 24 G-protein coupled receptor homolog US28 (R) Hydrophobic
Ile 10 65 CX VAL 24 G-protein coupled receptor homolog US28 (R) VdWContact
Thr 11 66 CX CYS 23 G-protein coupled receptor homolog US28 (R) HBAcceptor
Thr 11 66 CX CYS 23 G-protein coupled receptor homolog US28 (R) VdWContact
Thr 11 66 CX PRO 22 G-protein coupled receptor homolog US28 (R) VdWContact
Thr 16 71 N-loop ASP 17 G-protein coupled receptor homolog US28 (R) Hydrophobic
Ile 19 75 N-loop TYR 16 G-protein coupled receptor homolog US28 (R) Hydrophobic
Ala 32 92 30s-loop MET 174 G-protein coupled receptor homolog US28 (R) Hydrophobic
Ala 32 92 30s-loop MET 174 G-protein coupled receptor homolog US28 (R) VdWContact
Ala 32 92 30s-loop GLN 172 G-protein coupled receptor homolog US28 (R) VdWContact
Ser 33 94 30s-loop CYS 173 G-protein coupled receptor homolog US28 (R) HBDonor
Ser 33 94 30s-loop CYS 173 G-protein coupled receptor homolog US28 (R) VdWContact
Ser 33 94 30s-loop GLN 172 G-protein coupled receptor homolog US28 (R) VdWContact
Cys 34 95 30s-loop TYR 177 G-protein coupled receptor homolog US28 (R) VdWContact
Gly 35 96 30s-loop MET 174 G-protein coupled receptor homolog US28 (R) VdWContact
Gly 35 96 30s-loop THR 175 G-protein coupled receptor homolog US28 (R) VdWContact
Ile 40 102 B2 PRO 22 G-protein coupled receptor homolog US28 (R) Hydrophobic
Ile 40 102 B2 PRO 22 G-protein coupled receptor homolog US28 (R) VdWContact
Arg 47 114 40s-loop TYR 16 G-protein coupled receptor homolog US28 (R) VdWContact
Phe 49 116 B3 THR 21 G-protein coupled receptor homolog US28 (R) Hydrophobic
Phe 49 116 B3 TYR 16 G-protein coupled receptor homolog US28 (R) Hydrophobic
Phe 49 116 B3 TYR 16 G-protein coupled receptor homolog US28 (R) VdWContact
Cys 50 117 B3 ALA 20 G-protein coupled receptor homolog US28 (R) HBDonor
Cys 50 117 B3 ALA 20 G-protein coupled receptor homolog US28 (R) VdWContact
Cys 50 117 B3 PRO 22 G-protein coupled receptor homolog US28 (R) VdWContact

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