Interactions for 8K2X (chain L)
Structure details
- PDB ID: 8K2X open_in_new
- Protein: CXCL10_HUMAN
- Organism: Homo sapiens
- UniProt ID: P02778 open_in_new
- Method: Cryo-em
- Resolution: 3.2 Å
- Date: Nov. 29, 2023
- Reference: 10.1038/S41421-023-00617-0 open_in_new
- State: monomer
Chemokine diagram
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Interactions found in structure
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| Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
|---|---|---|---|---|---|
| Lys 1 | 134 | Helix | PHE 131 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Lys 1 | 134 | Helix | PHE 131 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Lys 1 | 134 | Helix | PHE 135 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Lys 1 | 134 | Helix | TYR 271 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Lys 1 | 134 | Helix | TYR 271 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Lys 1 | 134 | Helix | TYR 308 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Lys 1 | 134 | Helix | TYR 308 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Glu 2 | 135 | Helix | PHE 131 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Glu 2 | 135 | Helix | PHE 131 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Glu 2 | 135 | Helix | TRP 109 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Glu 2 | 135 | Helix | TRP 109 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Glu 2 | 135 | Helix | TYR 60 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Glu 2 | 135 | Helix | TYR 60 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Glu 2 | 135 | Helix | TYR 308 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Glu 2 | 135 | Helix | TYR 308 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Arg 3 | 136 | C-term | TRP 109 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Arg 3 | 136 | C-term | TRP 109 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Arg 3 | 136 | C-term | TYR 205 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Arg 3 | 136 | C-term | TYR 205 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Ser 4 | 137 | C-term | LYS 300 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Ser 4 | 137 | C-term | ASP 52 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | HBDonor |
| Ser 4 | 137 | C-term | ASP 52 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Lys 5 | 138 | C-term | GLN 204 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Lys 5 | 138 | C-term | ARG 212 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Lys 5 | 138 | C-term | ARG 216 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Arg 6 | 139 | C-term | GLN 204 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | HBDonor |
| Arg 6 | 139 | C-term | GLN 204 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Ser 7 | 140 | C-term | GLU 293 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Pro 8 | 141 | C-term | GLU 293 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Pro 8 | 141 | C-term | GLU 293 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Cationic |
| Pro 8 | 141 | C-term | CYS 290 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
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